CN103393590A - Nano ganoderma spore oil and production process and application thereof - Google Patents

Nano ganoderma spore oil and production process and application thereof Download PDF

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Publication number
CN103393590A
CN103393590A CN2013103441158A CN201310344115A CN103393590A CN 103393590 A CN103393590 A CN 103393590A CN 2013103441158 A CN2013103441158 A CN 2013103441158A CN 201310344115 A CN201310344115 A CN 201310344115A CN 103393590 A CN103393590 A CN 103393590A
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ganoderma spore
spore oil
nano
glossy ganoderma
lecithin
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CN2013103441158A
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CN103393590B (en
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李卫国
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Abstract

The invention discloses nano ganoderma spore oil, and a production process and an application thereof. The nano ganoderma spore oil comprises the following components by weight ratio: 15 to 30 parts of ganoderma spore oil, 15 to 35 parts of lysolecithin, and 3 to 8 parts of propylene glycol or isopropanol, wherein the lysolecithin can be replaced with lecithin, lauric fatty acid ester, polyoxyethylene sorbitan monooleate or sucrose fatty acid ester. The nano ganoderma spore oil can also comprise vitamin C, butyl hydroxy anisd, butylated hydroxytoluene, enhanceparaben or sodium paraben. The above components are stirred and mixed in a water bath according to the proportion, after initial homogenization and high pressure homogenization are carried out, the nano ganoderma spore oil can be obtained, wherein the particle size distribution of the ganoderma spore oil is 30 to 50 nm. The nano ganoderma spore oil product has good stability and good absorption effect, so that the ganoderma spore oil allows efficacies to be exerted normally, can be used for preparation of health-care products or cosmetics, and is especially suitable for preparation of health-care oral liquid or externally applied cosmetics.

Description

A kind of nano glossy ganoderma spore oil and production technology and application
Technical field
The present invention relates to a kind of nano glossy ganoderma spore oil and production technology and application.
Background technology
In China, since ancient times, just Ganoderma is regarded as to Herba mesonae chinensis, be the elixir of life of life lengthening.Chinese Pharmacopoeia 2010 editions publishes: the function of Ganoderma with cure mainly: " invigorating QI and tranquilization, relieving cough and asthma.For malaise, insomnia cardiopalmus, cough and asthma due to lung deficiency, asthenia is losed heart, anorexia." therefore, at present, a lot of people, taking ganoderma lucidum product, with invigorating QI and tranquilization, improve immunity, regain one's strength of body etc.
Loving beauty is part of human nature.Utilize lucid ganoderma beautifying, Gu exists.In Compendium of Material Medica, put down in writing Ganoderma: " its bitter in the mouth is flat, nontoxic, invigorating the spleen and replenishing QI, increase wisdom, good color, food is made light of one's life by commiting suicide not oldly for a long time, the angle prolongs life." at this, the beauty treatment that good color relation refers to.
In fact, though ancient times, the modern times, utilize lucid ganoderma beautifying, be all that to take be main, or take lucidum soaked juice or direct edible glossy ganoderma, the function of regulating health by Ganoderma, reach the purpose of beauty treatment.Almost do not act directly on the product on skin, particularly Ganoderma spore oil is not used for to cosmetics.
Ganoderma spore oil is through what extraction obtained, a kind of to have a highly active material from Ganoderma spore powder, is considered to the elite in elite in ganoderma lucidum product.It contains the fatsoluble vitamin of abundant Ganodenic acid, ganoderan, ganoderma lucidum triterpene, organic germanium and trace.Above-mentioned substance has different effects.In fact Ganoderma spore oil belongs to the mixture of these materials.
Although Ganoderma spore oil can have various purposes,, result of use is also not obvious.Its successful ground is limited by the characteristic of itself: fat-soluble.Owing to being fat-soluble (oils) material, oil does not dissolve in water for Ganoderma spore, in digestive system, be difficult to absorb, after taking, need to enter liver and carry out metabolism, absorption, and then bring into play its physiological function, like this, there is unavoidably the Ganoderma spore oil of considerable part just to be drained at digestive system, even enter the part Ganoderma spore oil of liver, also can't guarantee whole absorptions.In addition, for those weakly patient, particularly patients with liver deficiency, take Ganoderma spore oil and more increased the weight of burden of liver.
Equally, be used on cosmetics, because human skin is a natural cover for defense, it can stop that all external materials enter health, undressed Ganoderma spore oil, and its active substance also is difficult to transdermal, and the corium that enters into deep layer plays a role.Therefore, utilize lucid ganoderma beautifying, except oral, what be directly used in skin surface is empty talk substantially.
As can be seen here, in the use, obviously still there is very large defect in above-mentioned existing Ganoderma spore oil, and urgently is further improved.
Summary of the invention
The object of the present invention is to provide a kind of nano glossy ganoderma spore oil of good absorbing effect, can, so that the Ganoderma spore oil effect is able to normal performance, improve the utilization rate of Ganoderma spore oil.
Second purpose of the present invention is to provide the production technology of above-mentioned nano glossy ganoderma spore oil.
The 3rd purpose of the present invention is to provide the application of above-mentioned nano glossy ganoderma spore oil.
To achieve these goals, the present invention adopts following technical scheme:
A kind of nano glossy ganoderma spore oil, comprise each component of following weight proportion: Ganoderma spore oil 15-30 part, LYSOLECITHIN SUNLECITHIN A 15-35 part, propylene glycol or isopropyl alcohol 3-8 part.
Further, described LYSOLECITHIN SUNLECITHIN A replaces with lecithin, lauric fats acid esters, polyoxyethylenesorbitan sorbitan monooleate or sucrose fatty acid ester.
Further, described lecithin adopts modified lecithin, refined lecithin, purification lecithin; Described lauric fats acid esters adopts Tween-20 or polyglycereol monolaurate.
Further, also comprise vitamin C, Butylated hydroxyanisole, dibenzylatiooluene, Nipagin ester or Sodium Paraben, wherein, ascorbic content≤0.2g/kg, content≤the 0.4g/kg of Butylated hydroxyanisole or dibenzylatiooluene, the content≤0.5g/kg of Nipagin ester or Sodium Paraben.
Further, described each component all meets the food stage standard.
The production technology of above-mentioned nano glossy ganoderma spore oil comprises following steps: (1) takes each component according to described weight proportion; (2) water-bath, stir and make each component fully mix and mix; (3) by the material after miscible, be placed in homogenizer for liquid temperature 30-50 ℃, pressure 50-100mPa, carry out preliminary homogenizing; (4) mixed liquor after preliminary homogenizing is carried out to high pressure homogenize, temperature 30-50 ℃, pressure 150-200mPa, namely make nano glossy ganoderma spore oil, and wherein, the particle size distribution of Ganoderma spore oil is 30-50nm.
Further, in described step (2), first Ganoderma spore oil is placed in reactor, the water-bath still, be heated to 40 ℃-60 ℃, then adds successively all the other components, water-bath 10-60 minute, and mixing speed is 200-400rpm/min; In described step (3), preliminary homogenizing time is 20-40 minute.
Further, the bath temperature in described step (2) is 50 ℃, water-bath 30 minutes, and mixing speed is 300rpm/min; In described step (3), preliminary homogenizing time is 30 minutes; Described step (4) mesohigh homogenizing 3 times, every all over 30 minutes.
Above-mentioned nano glossy ganoderma spore oil can be used for preparing health product or cosmetics, is particularly useful for preparing health care oral liquid or cosmetics for external use.
Compared with prior art, the present invention has following beneficial effect:
Nano glossy ganoderma spore oil of the present invention, the fat-soluble characteristics of Ganoderma spore oil have thoroughly been changed, make it become water miscible material, thereby, improve the absorbance of oral Ganoderma spore oil, make every physiological function of Ganoderma spore oil normally to utilize comprehensively, improved the utilization rate of Ganoderma spore oil.During as cosmetics for external use, its active substance is easy transdermal also, and the corium that can enter into deep layer plays a role.
Below by embodiment, technical scheme of the present invention is described in further detail.
The specific embodiment
Below the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein, only for description and interpretation the present invention, is not intended to limit the present invention.
In the following embodiments, each component of nano glossy ganoderma spore oil all meets the food stage standard.
Embodiment 1
A kind of nano glossy ganoderma spore oil, comprise each component of following weight proportion: 15 parts of Ganoderma spore oils, 15 parts of LYSOLECITHIN SUNLECITHIN A, 3 parts of propylene glycol.
Embodiment 2
A kind of nano glossy ganoderma spore oil, comprise each component of following weight proportion: 20 parts of Ganoderma spore oils, 25 parts of LYSOLECITHIN SUNLECITHIN A, 5 parts of propylene glycol.
Embodiment 3
A kind of nano glossy ganoderma spore oil, comprise each component of following weight proportion: 30 parts of Ganoderma spore oils, 35 parts of LYSOLECITHIN SUNLECITHIN A, 8 parts of propylene glycol.
Embodiment 4
On any basis of embodiment 1-3, difference is: LYSOLECITHIN SUNLECITHIN A replaces with lecithin (modified lecithin, refined lecithin, purification lecithin), lauric fats acid esters, polyoxyethylenesorbitan sorbitan monooleate or sucrose fatty acid ester, and wherein the lauric fats acid esters can adopt Tween-20 or polyglycereol monolaurate.
Embodiment 5
On any basis of embodiment 1-3, difference is: propylene glycol replaces with isopropyl alcohol.
Embodiment 6
on any basis of embodiment 1-3, also can comprise vitamin C, Butylated hydroxyanisole, dibenzylatiooluene, Nipagin ester (ethylparaben) or Sodium Paraben (Sodium Methyl Hydroxybenzoate or nipagin A sodium), wherein, ascorbic content≤0.2g/kg(200ppm), preferred 50ppm-100ppm, the content of Butylated hydroxyanisole or dibenzylatiooluene≤0.4g/kg(400ppm), preferred 50ppm-300ppm, the content of Nipagin ester or Sodium Paraben≤0.5g/kg(500ppm), preferred 50ppm-300ppm.
Through experiment confirm, the nano glossy ganoderma spore pick up the oil rate of embodiment 1-6 can reach more than 95%, and existing Ganoderma spore oil is as oral liquid, and absorbance is generally less than 60%.
Embodiment 7
The production technology of the nano glossy ganoderma spore oil in above-described embodiment 1-6 comprises: said components is mixed in described ratio stirring in water bath, then can make nano glossy ganoderma spore oil through preliminary homogenizing, high pressure homogenize.Specifically comprise following steps:
(1) according to described weight proportion, take each component.
(2) Ganoderma spore oil is placed in reactor, the water-bath still, be heated to 40 ℃-60 ℃, the best is 50 ℃, then adds successively all the other components, water-bath 10-60 minute, best 30 minutes, mixing speed is 200-400rpm/min, and best 300rpm/min makes each component fully mix and mix.
(3) by the material after miscible, be placed in homogenizer for liquid temperature 30-50 ℃, pressure 50-100mPa, carry out preliminary homogenizing, 20-40 minute, the best is 30 minutes.
(4) mixed liquor after preliminary homogenizing is carried out to high pressure homogenize, temperature 30-50 ℃, pressure 150-200mPa, high pressure homogenize process circulation 3 times, each circulation is 30 minutes, namely makes nano glossy ganoderma spore oil, wherein, the particle size distribution of Ganoderma spore oil is 30-50nm.
Embodiment 8
The present embodiment is mainly the application example of nano glossy ganoderma spore oil, take the nano glossy ganoderma spore oil of embodiment 1-6 as substrate, can prepare health product or cosmetics, as nano glossy ganoderma spore oil health care oral liquid, nano glossy ganoderma spore oil Antifatigue oral liquid, nano glossy ganoderma spore pasta film, nano glossy ganoderma spore pasta frost etc., below as an example of nano glossy ganoderma spore oil health care oral liquid and nano glossy ganoderma spore pasta film example, illustrate:
(1) nano glossy ganoderma spore oil health care oral liquid, wherein, the quality percentage composition of nano glossy ganoderma spore oil is 10-30%, all the other are deionized water.
(2) nano glossy ganoderma spore pasta film, wherein, add vitamin E, vitamin A, vitamin C and deionized water again on the basis of nano glossy ganoderma spore oil, this facial film can play and brighten, speckle dispelling, antioxidative effect, increases skin elasticity.
Finally it should be noted that: the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment, the present invention is had been described in detail, for a person skilled in the art, it still can be modified to the technical scheme that previous embodiment is put down in writing, or part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (10)

1. a nano glossy ganoderma spore oil, is characterized in that, comprises each component of following weight proportion: Ganoderma spore oil 15-30 part, LYSOLECITHIN SUNLECITHIN A 15-35 part, propylene glycol or isopropyl alcohol 3-8 part.
2. nano glossy ganoderma spore oil according to claim 1, is characterized in that, described LYSOLECITHIN SUNLECITHIN A replaces with lecithin, lauric fats acid esters, polyoxyethylenesorbitan sorbitan monooleate or sucrose fatty acid ester.
3. nano glossy ganoderma spore oil according to claim 2, is characterized in that, described lecithin adopts modified lecithin, refined lecithin or purification lecithin; Described lauric fats acid esters adopts Tween-20 or polyglycereol monolaurate.
4. the described nano glossy ganoderma spore oil of according to claim 1-3 any one, it is characterized in that, also comprise vitamin C, Butylated hydroxyanisole, dibenzylatiooluene, Nipagin ester or Sodium Paraben, wherein, ascorbic content≤0.2g/kg, content≤the 0.4g/kg of Butylated hydroxyanisole or dibenzylatiooluene, the content≤0.5g/kg of Nipagin ester or Sodium Paraben.
5. nano glossy ganoderma spore oil according to claim 4, is characterized in that, described each component all meets the food stage standard.
6. the production technology of the described nano glossy ganoderma spore oil of claim 1-5 any one, is characterized in that, comprises following steps:
(1) according to described weight proportion, take each component;
(2) water-bath, stir and make each component fully mix and mix;
(3) by the material after miscible, be placed in homogenizer for liquid temperature 30-50 ℃, pressure 50-100mPa, carry out preliminary homogenizing;
(4) mixed liquor after preliminary homogenizing is carried out to high pressure homogenize, temperature 30-50 ℃, pressure 150-200mPa, namely make nano glossy ganoderma spore oil, and wherein, the particle size distribution of Ganoderma spore oil is 30-50nm.
7. the production technology of nano glossy ganoderma spore oil according to claim 6, it is characterized in that, in described step (2), first Ganoderma spore oil is placed in reactor, the water-bath still, be heated to 40 ℃-60 ℃, then adds successively all the other components, water-bath 10-60 minute, mixing speed is 200-400rpm/min; In described step (3), preliminary homogenizing time is 20-40 minute.
8. the production technology of nano glossy ganoderma spore oil according to claim 7, is characterized in that, the bath temperature in described step (2) is 50 ℃, water-bath 30 minutes, and mixing speed is 300rpm/min; In described step (3), preliminary homogenizing time is 30 minutes; Described step (4) mesohigh homogenizing 3 times, every all over 30 minutes.
9. the application of the described nano glossy ganoderma spore oil of claim 1-5 any one in preparing health product or cosmetics.
10. the application of nano glossy ganoderma spore oil according to claim 9 in preparing health product or cosmetics is characterized in that described nano glossy ganoderma spore oil is for the preparation of health care oral liquid or cosmetics for external use.
CN201310344115.8A 2013-08-08 2013-08-08 A kind of production technology of nano ganoderma spore oil Expired - Fee Related CN103393590B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853286A (en) * 2016-04-29 2016-08-17 山东复大生物科技有限公司 Skin care product containing ganoderma lucidum spore oil and preparation method for ganoderma lucidum spores oil of skin care product
CN108117926A (en) * 2018-02-27 2018-06-05 江苏金洲粮油食品有限公司 A kind of fit-keeping flax seed oil extractant

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903228A (en) * 2006-07-03 2007-01-31 李颖 Prepn. of self-emulsion of glossy ganoderma spore oil, and its prepn. method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903228A (en) * 2006-07-03 2007-01-31 李颖 Prepn. of self-emulsion of glossy ganoderma spore oil, and its prepn. method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙万成: "溶血磷脂制备含沙棘油微乳液的研究", 《现代食品科技》, vol. 22, no. 04, 31 December 2006 (2006-12-31), pages 42 - 45 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853286A (en) * 2016-04-29 2016-08-17 山东复大生物科技有限公司 Skin care product containing ganoderma lucidum spore oil and preparation method for ganoderma lucidum spores oil of skin care product
CN108117926A (en) * 2018-02-27 2018-06-05 江苏金洲粮油食品有限公司 A kind of fit-keeping flax seed oil extractant

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