CN103393589A - Bath lotion - Google Patents
Bath lotion Download PDFInfo
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- CN103393589A CN103393589A CN2013102751072A CN201310275107A CN103393589A CN 103393589 A CN103393589 A CN 103393589A CN 2013102751072 A CN2013102751072 A CN 2013102751072A CN 201310275107 A CN201310275107 A CN 201310275107A CN 103393589 A CN103393589 A CN 103393589A
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- bath gel
- bath lotion
- deionized water
- antibacterial
- surfactant
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Abstract
The invention belongs to a sanitation product field, and is intended to provide an efficient and safe sterilization bath lotion product prepared by a modern biology technology. The bath lotion is mainly composed of an anionic surfactant, a nonionic surfactant, an ampholytic surfactant, deionized water, a thickening agent, a nutritive agent, an emollient and glycerin, and the bath lotion is characterized in that the bath lotion contains a bactericide which is a broth extract product of bacillus subtilis. A method for preparing the bath lotion comprises the following steps of: adding deionized water into a reaction vessel, heating, adding the anionic surfactant, then uniformly stirring, regulating pH value until the temperature descends to 40 DEG C, adding the nutrition agent, making up with deionized water, uniformly stirring at 20-30 revolutions per minute, and degassing. The bath lotion not only implements dirt removal function, but also has good sterilization and disinfection effects. The bactericide added in the bath lotion has an anticorrosion function, and has safety and high efficiency characteristics.
Description
Technical field
The invention belongs to field of hygiene products, relate to a kind of special bath gel.
Background technology
On skin, formed dirt together with scurf of people's perspiration and airborne dust and human body etc.On dirt, assembled a large amount of microorganisms, some are wherein just arranged may be sex pheromone, and these health to people are brought certain threat.Especially some outdoor labourers, due to the restriction of sanitary condition, on skin, dirt is more, and the above has assembled a large amount of microorganisms, and some wherein just may be arranged is the microorganisms of causing a disease.At sex pheromones such as hospitals, assemble in more environment, sex pheromone also can be gathered on skin.On skin, temperature relatively is suitable for the breeding of microorganism, and sex pheromone may obtain a large amount of breedings.Bath gel can be removed the dirt of skin, can remove a certain amount of sex pheromone simultaneously, but our common bath gel does not possess sterilizing function, so can't thoroughly remove and pathogenic microbe killing.Therefore may bring threat to our health.Bath gel in the market seldom has sterilizing function.
In bath gel, generally add antiseptic and prevent the putrid and deteriorated of bath gel at present, these antiseptic have certain danger to the mankind's health, may certain stimulation be arranged to skin simultaneously.That in the present invention, adds has the antiseptical function by the pure natural fermentation raw material through the antibacterial that modern biotechnology processes, and has characteristics safely and efficiently.In bath gel without adding again antiseptic.
Summary of the invention
The purpose of this invention is to provide a kind of highly effective and safe, adopt the bath gel product of modern biotechnology product processing.
Key component of the present invention comprises the compositions such as anion surfactant, non-ionic surface active agent, amphoteric surfactant, antibacterial, thickening agent, nutrient, emollient, glycerol, essence, deionized water.
Technical characteristics of the present invention be added have inexpensive, highly effective and safe, the antibacterial through modern biotechnology processing of All Pure Nature.Antibacterial is bacillus subtilis (Bacillussubtilis) fermentation broth extract, this bacterial strain has been preserved in China Committee for Culture Collection of Microorganisms's common micro-organisms center on April 16th, 2012, the preservation address is positioned at Yard 1, BeiChen xi Road, Chaoyang District, Beijing City No. 3, (postcode 100101), deposit number are CGMCCNo.6012.
Fungus characteristic is as follows:
1. somatic cells is Gram-positive living in direct rod shape, spore or that near-end is given birth to.
2. colony characteristics is that white is circular, protuberance, and smooth surface, opaque, moistening, provoke adhesion.
3. can utilize various saccharides, as glucose, galactose, xylose, cellobiose, cottonseed sugar etc.; Produce amylase, protease, can gelatin hydrolysate, V.P, the C.I. 13020. positive.
4. the suitableeest cultivation temperature is 37 ℃, optimum pH 7.0.
This bacterium classification status is as follows: antibacterial territory (Bacteria); Firmicutes (Firmicutes); Bacillus cereus guiding principle (Bacillales); Bacillus cereus order (Bacillaceae); Bacillaceae (Bacillus); Bacillus (Bacillus); Bacillus subtilis strain (Bacillussubtilis).
In the present invention, the preparation method of fermentation broth extract is as follows:
The seed culture medium of bacterial strain is broth bouillon, Carnis Bovis seu Bubali cream 2g wherein, peptone 8g, NaCl5g, water 1000ml, pH value 7.0～7.2, high pressure steam sterilization.
The seed liquor condition of culture: cultivation temperature is 33 ℃, and shaking speed is 140 rev/mins, and fermentation time is 13 hours.
Inoculum concentration is 8%, is conducive to the formation of antibacterial substance.
The fermentation fermentation medium consists of: glucose 0.3%, peptone 1%, NaCl0.5%, MgSO
4.7H
2O0.7%, KH
2PO
40.7%, pH8.0.
Fermentation culture conditions is: cultivation temperature is 33 ℃, and shaking speed is 140 rev/mins, and fermentation time is about 24 hours.
From fermentation liquid, extracting the antibacterial substance method, it is organic solvent precipitation method.
At first by the fermentation liquid high speed centrifugation, temperature 0-4 ℃, rotating speed are 8000 rev/mins, centrifugal ten minutes, keep supernatant.
(methanol: ethanol=1:6), fully dissolving is placed in there-necked flask, and 40 degrees centigrade of temperature are controlled in water-bath, and mixing speed is 60rpm, and the time is 5 hours, collects organic facies, adopts vacuum distillation method to remove organic solvent in supernatant, to add the equal-volume organic solvent.Vapo(u)rizing temperature 30-60 ℃, distilled 20 minutes, and organic solvent is removed.The collecting precipitation material.Obtain antibacterial.
The crude extract of Fungicidal substance, with after water dissolution, concentration is the 1%(mass volume ratio).Lysate can kill common pathogenic bacterium effectively.For example not only can effectively kill escherichia coli, Salmonella, the pathogenic microorganism that golden yellow common coccus etc. are common, and can kill the common coccus of methicillin-resistant staphylococcus.
This bactericidal liquid has high safety, in the emergency toxicology experiment, we gavage 5 groups of 200 mouse with this bactericidal liquid, and the mouse of experimental group none occur dead, and bacillus subtilis is present in occurring in nature widely, and many important industrial bacterial strains are exactly bacillus subtilis.Substantially can conclude that this bactericidal liquid is safe for user, can relievedly use.
bath gel method for making of the present invention is simple, adding the part deionized water enters in reactor, its temperature is heated to 60-70 ℃ and adds man-hour by anion surfactant 1-10%, non-ionic surface active agent 1-5%, amphoteric surfactant 1-5%, glycerol 3-6%, antilubricant 1-10%, emollient 0.5-3% and deionized water and stirring are even, cool the temperature to 40 ℃, with citric acid, the pH value of solution is transferred to 6.5-7.0, add nutrient 0.5-3%, antibacterial 0.01-1%, essence 0.0001-0.0004%, thickening agent 1-4%, insufficient section deionized water polishing, stir, speed of agitator can be controlled in 20-30 rev/min, carry out the feed liquid that is stirred degassed, adopt vacuum outgas, negative pressure can be controlled in 5Mpa, removal forms in the stirring and dissolving process bubble, reduce the air content of material, mixed liquor is carried out to packing, can obtain bath gel.Ratio accounts for the percentage by weight of product gross weight for each component herein.
Anion surfactant is sodium lauryl sulphate, and is at least a in Sodium Alcohol Ether Sulphate.
Non-ionic surface active agent can be alkylphenol polyoxyethylene, and is at least a in fatty alcohol-polyoxyethylene ether.
Amphoteric surfactant is dodecyldimethylammonium hydroxide inner salt, and is at least a in dodecayl dimethyl amine oxide.
Thickening agent is polyethylene glycol mono stearate
Glycerol, as wetting agent, can prevent reduced water content in skin, and can improve the tolerance to cold of product, when product is used, can not produce the variation of form.
Nutrient comprises one or more in vitamin or collagen protein.
Emollient comprises in water-soluble modified silicone oil, cation-modified silicone oil or amino-modified silicone oil at least a.
Essence used can add according to the odor type of product, makes product have different odor types, meets the needs of different consumers.
The invention has the beneficial effects as follows: the present invention, not only realize the function of bath gel removal dirt, and possessed the function of good sterilization and sterilization, particularly can kill the characteristic of methicillin-resistant staphylococcus aureus.The emergency toxicology experiment has also verified the antibacterial that adds in this detergent people and animals to be had to very high safety.Scientist has found methicillin-resistant staphylococcus aureus in 1961, find that at present it spreads all over the world, and becomes important infectious bacteria, has brought great threat for people's health.The production of the antibacterial that adds in bath gel, utilize fermentation raw material with low cost, adopts modern biotechnology, and technique is simple, and is with low cost.Make the present invention, become a kind of sterilizing power strong, safety, cheapness, bath gel with high content of technology.
That in the present invention, adds has the antiseptical function by the pure natural fermentation raw material through the antibacterial that modern biotechnology processes, and has characteristics safely and efficiently.In bath gel without adding again antiseptic.
The specific embodiment
Induction mutation of bacterium
Take the ultraviolet mutagenesis method: take CICC10023 as starting strain, make bacteria suspension, coat on the culture medium plate, after ultra-vioket radiation 90s, in 37 ℃ of incubators, cultivate.
Bacterial screening
From the 90s plate, choose 30 single bacterium colonies of looking strong, be inoculated on inclined-plane, in 37 ℃ of incubators, cultivated 0--4 ℃ of stored refrigerated 24 hours; With original strain in contrast, adopt the conventional herd breeding condition, sodium carboxymethyl cellulose is as carbon source and Proteolytic enzyme circle method screening cellulase-producing and the strong bacterial strain of protease, screening obtains cellulase-producing and strong bacterial strain bacillus subtilis (Bacillus subtilis) L1 of protease, this bacterial strain cellulase-producing energy force rate original strain has improved 25%, produces protease energy force rate original strain and has improved 52%.In the center preservation of Chinese common micro-organisms culture presevation administration committee's common micro-organisms, deposit number is CGMCCNo6012 by this strain.
This product bacillus subtilis used (Bacillus subtilis) strain, this bacterial strain has been preserved in China Committee for Culture Collection of Microorganisms's common micro-organisms center on April 16th, 2012, the preservation address is positioned at Yard 1, BeiChen xi Road, Chaoyang District, Beijing City No. 3, (postcode 100101), deposit number are CGMCC No6012.
Research shows by experiment: antibacterial have good inhibition escherichia coli, staphylococcus aureus, etc. the characteristics of pathogenic bacterium.
The invention will be further described below in conjunction with specific embodiment, but be not limited to embodiment.
Embodiment 1
prepare 100 kilograms of products, 60 kilograms of deionized waters are added in reactor, its temperature is heated to 70 ℃, then add successively the 4.5kg Sodium Alcohol Ether Sulphate, 3.2kg fatty alcohol-polyoxyethylene ether, the 2kg dodecyldimethylammonium hydroxide inner salt, 3kg glycerol, the 4kg antilubricant, then add the water-soluble modified silicone oil of 0.5kg to stir, speed of agitator is unsuitable too high, can be controlled in 20-30 rev/min, after stirring, cool the temperature to 40 ℃, with citric acid, the pH value of solution is transferred to 6.5, add the 1kg collagen protein, 0.2kg antibacterial, rose essence 0.0001%, the 2kg polyethylene glycol mono stearate, insufficient section adds the deionized water polishing, stir, speed of agitator can be controlled in 20-30 rev/min, carry out the feed liquid that is stirred degassed, adopt vacuum outgas, negative pressure can be controlled in 5Mpa, removal forms in the stirring and dissolving process bubble, reduce the air content of material, mixed liquor is carried out to packing, can obtain bath gel.
This product and Safeguard product adopt conventional microorganism detection bactericidal effect, and result of the test shows, product of the present invention under equal conditions bactericidal effect improves 60-80% than Safeguard, and bactericidal effect is obvious.Escherichia coli, Salmonella, golden yellow common coccus are selected in microorganism.
Embodiment 2
prepare 100 kilograms of products, 70 kilograms of deionized waters are added in reactor, its temperature is heated to 60 ℃, then add successively the 6kg sodium lauryl sulphate, the 4kg alkylphenol polyoxyethylene, the 4kg dodecayl dimethyl amine oxide, 5kg glycerol, the 6kg antilubricant, then add the water-soluble modified silicone oil of 1kg to stir, speed of agitator is unsuitable too high, can be controlled in 20-30 rev/min, after stirring, cool the temperature to 40 ℃, with citric acid, the pH value of solution is transferred to 7, add the 0.5kg collagen protein, 0.01kg antibacterial, rose essence 0.0002%, the 1kg polyethylene glycol mono stearate, insufficient section adds the deionized water polishing, stir, speed of agitator can be controlled in 20-30 rev/min, carry out the feed liquid that is stirred degassed, adopt vacuum outgas, negative pressure can be controlled in 5Mpa, removal forms in the stirring and dissolving process bubble, reduce the air content of material, mixed liquor is carried out to packing, can obtain bath gel.
Claims (7)
1. bath gel, by anion surfactant, non-ionic surface active agent, amphoteric surfactant, deionized water, thickening agent, nutrient, emollient and glycerol, formed, it is characterized in that, in described bath gel, contain antibacterial, described antibacterial is the fermentation broth extract of bacillus subtilis CGMCC6012.
2. bath gel according to claim 1, is characterized in that, the interpolation part by weight of described antibacterial is 0.01～1%.
3. bath gel according to claim 1, is characterized in that, described anion surfactant is at least a in sodium lauryl sulphate or Sodium Alcohol Ether Sulphate.
4. bath gel according to claim 1, is characterized in that described non-ionic surface active agent is at least a in alkylphenol polyoxyethylene or fatty alcohol-polyoxyethylene ether.
5. bath gel according to claim 1, is characterized in that described amphoteric surfactant is at least a in dodecyldimethylammonium hydroxide inner salt or dodecayl dimethyl amine oxide.
6. bath gel according to claim 1, is characterized in that described thickening agent is polyethylene glycol mono stearate.
7. bath gel preparation method according to claim 1, it is characterized in that, comprise the steps: to add deionized water in reactor, be heated to 60-70 ℃, add anion surfactant 1～10%, non-ionic surface active agent 1～5%, amphoteric surfactant 1～5%, glycerol 3～6%, antilubricant 1～10%, emollient 0.5～3% stirs, temperature is down to 40 ℃, adjust pH value to transfer to 6.5～7.0, add nutrient 0.5～3%, antibacterial 0.01～1%, essence 0.0001-0.0004%, thickening agent 1～4%, the deionized water polishing, stir, speed of agitator is at 20～30 rev/mins, degassed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102751072A CN103393589A (en) | 2012-07-14 | 2013-07-03 | Bath lotion |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210245130.2 | 2012-07-14 | ||
| CN 201210245130 CN103142454A (en) | 2012-07-14 | 2012-07-14 | Shower gel |
| CN2013102751072A CN103393589A (en) | 2012-07-14 | 2013-07-03 | Bath lotion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103393589A true CN103393589A (en) | 2013-11-20 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210245130 Pending CN103142454A (en) | 2012-07-14 | 2012-07-14 | Shower gel |
| CN2013102751072A Pending CN103393589A (en) | 2012-07-14 | 2013-07-03 | Bath lotion |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201210245130 Pending CN103142454A (en) | 2012-07-14 | 2012-07-14 | Shower gel |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104823971A (en) * | 2015-03-21 | 2015-08-12 | 威海翔宇环保科技股份有限公司 | Sterilization synergist used for non-oxidative bactericide |
| CN108066228A (en) * | 2018-02-09 | 2018-05-25 | 杭州纳美智康科技有限公司 | A kind of moisturizing antibacterial bath cream and preparation method thereof |
| CN108498447A (en) * | 2018-03-15 | 2018-09-07 | 广州佳静健康产业有限公司 | A kind of plant enzyme cleaning bubble liquid preparation |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106473940A (en) * | 2016-11-29 | 2017-03-08 | 佛山市芊茹化妆品有限公司 | A kind of multiple-effect bath gel and preparation method thereof |
| CN111110580A (en) * | 2020-02-12 | 2020-05-08 | 常德集智生物科技有限公司 | Green antibacterial and bactericidal shower gel |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101507700A (en) * | 2008-03-12 | 2009-08-19 | 北京绿岛缘蜂产品有限公司 | High-efficiency sterilization shower cream |
-
2012
- 2012-07-14 CN CN 201210245130 patent/CN103142454A/en active Pending
-
2013
- 2013-07-03 CN CN2013102751072A patent/CN103393589A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101507700A (en) * | 2008-03-12 | 2009-08-19 | 北京绿岛缘蜂产品有限公司 | High-efficiency sterilization shower cream |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104823971A (en) * | 2015-03-21 | 2015-08-12 | 威海翔宇环保科技股份有限公司 | Sterilization synergist used for non-oxidative bactericide |
| CN108066228A (en) * | 2018-02-09 | 2018-05-25 | 杭州纳美智康科技有限公司 | A kind of moisturizing antibacterial bath cream and preparation method thereof |
| CN108498447A (en) * | 2018-03-15 | 2018-09-07 | 广州佳静健康产业有限公司 | A kind of plant enzyme cleaning bubble liquid preparation |
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| Publication number | Publication date |
|---|---|
| CN103142454A (en) | 2013-06-12 |
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Application publication date: 20131120 |