CN103392872A - Food-grade health tea soluble granules capable of improving sleep - Google Patents

Abstract

The invention discloses food-grade health tea soluble granules capable of improving sleep, and belongs to the field of nutritional foods. Effects are excellent, and efficacy is quick. The food-grade health tea soluble granules comprise raw materials such as poria cocos, wolfberry, spine date seed, and armillaria mellea; is capable of reinforcing the vital energy and consolidating the constitution, enhancing the immunity, and reinforcing Qi and nourishing blood, and has advantages of excellent effects and quick efficacy.

Description

A kind of food health preserving tea electuary that improves sleep

Technical field

The invention belongs to the nutraceutical field.

Background technology

In actual life, many elderly's sleeps are bad, or difficulty falling asleep, can't fall asleep for a long time; Perhaps easily wake up with a start, after waking up, have difficulty in going to sleep again; Perhaps the length of one's sleep short, do not have enough sleep every night 5 hours.The elderly has a sleepless night for a long time by serious harm health.We know, if serious sleep-disorder has appearred in the people, should go to hospital to see the doctor, the medication treatment of following the doctor's advice.Present considerable the elderly wishes to overcome insomnia by the way of dietotherapy.But the food that improves in the market sleep is also few, and have an effect not obviously, the slower problem that takes effect, everybody does not feel quite pleased this.

For problem set forth above, the invention provides a kind of food health preserving tea electuary that improves sleep, it is obvious not that it can solve in the past in this series products effect, slower problem takes effect, have the righting reinforcing, strengthen immunity, the effect of nourishing qi and blood sleeping, have effective, the advantage of instant effect.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of food health preserving tea electuary that improves sleep, adopt Chinese medicine material and raw-food material preparation, and formula is by weight ratio:

3-5 parts of 4-7 parts of spina date seeds of 4-7 portions of fruits of Chinese wolfberry of Poria cocos

5-9 parts of halimasch

The food health preserving tea electuary of this improvement sleep is made by following method:

(1) by above-mentioned weight proportion, Poria cocos is extracted to pachymaran, and process is: after Poria cocos was pulverized, 1:10 was added to the water with the feed liquid mass ratio, 95 ℃ of stirring and leaching 4h, separate the aqueous solution, residue is carried 1 time again, merging filtrate, with ion-exchange, remove small molecular weight impurity, through the ethanol precipitation, obtain crude product, then dialyse again after pepsin, papain and trypsin treatment, obtain pachymaran extract fine powder;

(2) by above-mentioned weight proportion, the fruit of Chinese wolfberry is extracted to LBP-X, process is: the fruit of Chinese wolfberry is placed in to 60 ℃ of oven dry of drying box, after taking-up, puts into drier 24h; The fruit of Chinese wolfberry after drying is processed grinds, put in common reflux, add under 60 ℃ of the methyl alcohol of 2 times of amounts the backflow degreasing 2 times, each 2h, leach solvent, residue is air-dry rear with 60 ℃ of backflows of concentration 80% appropriate amount of ethanol 2 times, and each 2h, reclaim ethanol, again with 50 ~ 60 ℃ of water extractions 2 times, each 2h of extraction time, solid-to-liquid ratio is 1: 20, merging filtrate is concentrated again with 5 times of ethanol precipitations of measuring concentration 95%, place 24h, suction filtration, gained solid content successively with concentration 95% ethanol, absolute ethyl alcohol, acetone wash successively, vacuum drying, obtain the LBP-X meal;

(3) by above-mentioned weight proportion, halimasch is extracted, process is: Armillaria mellea is put into to the culture medium that corn flour is cooked, and the armillaria mycelium that ferments to obtain, extract water-soluble polysaccharide with the hot water extraction, extraction conditions is: solid-to-liquid ratio 1:5,90 ℃ of temperature, time 2.5h, filter, Vacuum Concentration, drying and crushing obtain the armillaria mellea fine powder;

(4) by above-mentioned weight proportion, often return water extraction process to extract spina date seed, make medicinal extract, oven dry is pulverized, and obtains the extract fine powder, above-mentioned (1), (2), (3) extract fine powder mix, stir, make fine particle, the pouch of packing into, every pouch includes extract 3 grams, makes the food health preserving tea electuary that improves sleep.

Raw material in this formula is all that medicine-food two-purpose kind and the food that the Ministry of Public Health announces can be used kind.

The present invention develops meticulously according to the folk tradition formula.The traditional Chinese medical science thinks, difficulty falling asleep, that sleep is bad is deficient with the human righteousness, qi and blood lose foster have important associated.Control when the righting reinforcing, strengthen immunity of organisms, nourishing qi and blood sleeping.This theory with " sleep is a kind of immunologic process " of Harvard University's proposition in 1984 is consistent, namely " along with the enhancing process of immunity, human body is generated heat and start dark the dormancy ".Among we, Poria cocos, matrimony vine are all the righting good merchantable brands, Poria cocos blood-enrich, mental-tranquilization, and pachymaran energy activated lymphocyte T cell and the B cell of its Poria cocos extraction, anti-atrophy of thymus gland, strengthen the phagocytic activity of macrophage etc.; The LBP-X passage, nourishing blood, nourishing liver and kidney, promote the human body hematopoiesis function; Poria cocos and fruit of Chinese wolfberry mutual reinforcement between are for using, righting reinforcing, the prosperous hemapodium of gas, to strengthen immunity of organisms more remarkable, too much " rubbish " such as lipids in blood is removed in " removing " effect of immunity, make blood clean, stickiness descends, and mobility improves, the cranial nerve blood supply is full, impaired cranial nerve is repaired in " reparation " effect of immunity, makes it to recover original sleep function, and this is to overcome people's difficulty falling asleep, the not dark key of sleep.Minister all is improved the effect of sleep with spina date seed, halimasch, the spina date seed water extract all has sedative-hypnotic effect to mouse, cavy, cat, rabbit, dog, can defend the effect of barbital sodium to mouse sleep time by significant prolongation; Armillaria mellea can extend the length of one's sleep, 10 mouse of zoopery Meizu, after injection halimasch water formulation 15 ~ 30min, defend barbital sodium 46mg/kg, the length of one's sleep between extremely recovering from righting reflex loss is as evaluation criteria, control group is 109min, aqua 10 g/kg are 152min(P<0.05), aqua 20g/kg is 414min(P<0.001), show the obvious effect that extends the length of one's sleep; Spina date seed is use with halimasch phase 5, and the former has sedation, and the latter extends the length of one's sleep, effect stack, better effects if.Make a general survey of full side's compatibility, complement each other, bring out the best in each other, play altogether the righting reinforcing, strengthen immunity, the merit of nourishing qi and blood sleeping, have effective, the advantage of instant effect.

 

The specific embodiment

By following embodiment, the present invention is done and illustrates:

1, get following formula (weight is unit by gram):

The Poria cocos 4000 gram fruit of Chinese wolfberry 4000 gram spina date seed 3000 grams

Halimasch 5000 grams

Press afore mentioned rules weight, with the way of content of the present invention (1), (2), (3), (4), respectively Poria cocos, the fruit of Chinese wolfberry, halimasch, spina date seed are extracted, be total to obtain extract fine powder 960 grams; Mix, stir, make fine particle, the pouch of packing into, every pouch include extract 3 grams, make food health preserving tea electuary 320 pouches that improve sleep.

2, get following formula (weight is unit by gram)

The Poria cocos 7000 gram fruit of Chinese wolfberry 7000 gram spina date seed 5000 grams

Halimasch 9000 grams

By above-mentioned same method, make food health preserving tea electuary 560 pouches that improve sleep, every pouch includes extract 3 grams.

3, get following formula (by weight):

4 parts of 5 parts of spina date seeds of 5 portions of fruits of Chinese wolfberry of Poria cocos

6 parts of halimasch

By above-mentioned same method, make the food health preserving tea electuary that improves sleep, every pouch includes extract 3 grams.

4, get following formula (by weight):

4 parts of 6 parts of spina date seeds of 6 portions of fruits of Chinese wolfberry of Poria cocos

8 parts of halimasch

By above-mentioned same method, make the food health preserving tea electuary that improves sleep, every pouch includes extract 3 grams.

Clinical data:

The present invention is take traditional Chinese medical science insomnia as example, through 25 routine clinical observation experiments.Selecting the tcm diagnosis insomnia is standard: difficulty falling asleep, sleep not deeply, easily wake up with a start, early awakening, dreaminess, non-the sleeping of sleeping seemingly; Every night the length of one's sleep less than 6 hours; After sleep finished, health was tired, limb is soft unable.As above symptom, can make a definite diagnosis.In making a definite diagnosis the object of observation, the male sex's 13 examples, women's 12 examples, without other serious disease, the age is 35 ~ 72 years old, the mean age is 50.7 years old.

Efficacy determination:

1, produce effects: fall asleep fast, sleep is dark, easily wakes up with a start, early awakening significantly improves; Sleep every night more than 7 hours; Tiredly after sleep finishes eliminate, with it energetically.

2, effective: difficulty falling asleep, sleep do not make moderate progress deeply; The length of one's sleep is more than 6 hours every night.

3, invalid: symptom is unchanged.

During clinical testing, withdraw other medicines and health nutrient, take the food health preserving tea electuary of the improvement sleep of the specific embodiment of the invention 2 making, observing 3 months is a course for the treatment of.Instructions of taking: every day 1 time, each 1 pouch, every pouch include extract 3 grams, warm boiled water after meal, and after 1 month, symptom namely has alleviation, and after taking 3 months, symptom is obviously improved.In 25 people of clinical trial, produce effects 12 people, effective 10 people, invalid 3 people, total effective rate 88%.

Claims (1)

1. food health preserving tea electuary that improves sleep is characterized in that: described health preserving tea is to adopt Chinese medicine material and raw-food material preparation, and the weight proportion of Chinese medicine material and raw-food material is:

3-5 parts of 4-7 parts of spina date seeds of 4-7 portions of fruits of Chinese wolfberry of Poria cocos

5-9 parts of halimasch

The food health preserving tea electuary of this improvement sleep is made by following method:

(1) by above-mentioned weight proportion, Poria cocos is extracted to pachymaran, and process is: after Poria cocos was pulverized, 1:10 was added to the water with the feed liquid mass ratio, 95 ℃ of stirring and leaching 4h, separate the aqueous solution, residue is carried 1 time again, merging filtrate, with ion-exchange, remove small molecular weight impurity, through the ethanol precipitation, obtain crude product, then dialyse again after pepsin, papain and trypsin treatment, obtain pachymaran extract fine powder;

(2) by above-mentioned weight proportion, the fruit of Chinese wolfberry is extracted to LBP-X, process is: the fruit of Chinese wolfberry is placed in to 60 ℃ of oven dry of drying box, after taking-up, puts into drier 24h; The fruit of Chinese wolfberry after drying is processed grinds, put in common reflux, add under 60 ℃ of the methyl alcohol of 2 times of amounts the backflow degreasing 2 times, each 2h, leach solvent, residue is air-dry rear with 60 ℃ of backflows of concentration 80% appropriate amount of ethanol 2 times, and each 2h, reclaim ethanol, again with 50 ~ 60 ℃ of water extractions 2 times, each 2h of extraction time, solid-to-liquid ratio is 1: 20, merging filtrate is concentrated again with 5 times of ethanol precipitations of measuring concentration 95%, place 24h, suction filtration, gained solid content successively with concentration 95% ethanol, absolute ethyl alcohol, acetone wash successively, vacuum drying, obtain the LBP-X meal;

(3) by above-mentioned weight proportion, halimasch is extracted, process is: Armillaria mellea is put into to the culture medium that corn flour is cooked, and the armillaria mycelium that ferments to obtain, extract water-soluble polysaccharide with the hot water extraction, extraction conditions is: solid-to-liquid ratio 1:5,90 ℃ of temperature, time 2.5h, filter, Vacuum Concentration, drying and crushing obtain the armillaria mellea fine powder;

(4) by above-mentioned weight proportion, often return water extraction process to extract spina date seed, make medicinal extract, oven dry is pulverized, and obtains the extract fine powder, above-mentioned (1), (2), (3) extract fine powder mix, stir, make fine particle, the pouch of packing into, every pouch includes extract 3 grams, makes the food health preserving tea electuary that improves sleep.