CN103361209B - Fructus cnidii inflammation diminishing compound perfumed soap - Google Patents
Fructus cnidii inflammation diminishing compound perfumed soap Download PDFInfo
- Publication number
- CN103361209B CN103361209B CN201310193043.1A CN201310193043A CN103361209B CN 103361209 B CN103361209 B CN 103361209B CN 201310193043 A CN201310193043 A CN 201310193043A CN 103361209 B CN103361209 B CN 103361209B
- Authority
- CN
- China
- Prior art keywords
- fructus cnidii
- parts
- soap
- sodium
- perfumed soap
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000344 soap Substances 0.000 title claims abstract description 45
- 206010061218 Inflammation Diseases 0.000 title abstract description 5
- 230000003467 diminishing effect Effects 0.000 title abstract 4
- 230000004054 inflammatory process Effects 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000002994 raw material Substances 0.000 claims abstract description 14
- -1 amino betaine Chemical compound 0.000 claims abstract description 8
- GGXKEBACDBNFAF-UHFFFAOYSA-M sodium;hexadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCC([O-])=O GGXKEBACDBNFAF-UHFFFAOYSA-M 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000011734 sodium Substances 0.000 claims description 11
- 229910052708 sodium Inorganic materials 0.000 claims description 11
- 239000002131 composite material Substances 0.000 claims description 9
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 8
- 239000003352 sequestering agent Substances 0.000 claims description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- PDIZYYQQWUOPPK-UHFFFAOYSA-N acetic acid;2-(methylamino)acetic acid Chemical compound CC(O)=O.CC(O)=O.CNCC(O)=O PDIZYYQQWUOPPK-UHFFFAOYSA-N 0.000 claims description 5
- 125000002252 acyl group Chemical group 0.000 claims description 5
- 239000003921 oil Substances 0.000 claims description 5
- 235000019198 oils Nutrition 0.000 claims description 5
- GRZMEERIPCJGSO-UHFFFAOYSA-N oxalic acid;sodium Chemical compound [Na].[Na].OC(=O)C(O)=O GRZMEERIPCJGSO-UHFFFAOYSA-N 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims description 5
- 235000019864 coconut oil Nutrition 0.000 claims description 4
- 239000003240 coconut oil Substances 0.000 claims description 4
- 239000006260 foam Substances 0.000 abstract description 4
- 230000007794 irritation Effects 0.000 abstract description 2
- 230000001954 sterilising effect Effects 0.000 abstract description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 229940047642 disodium cocoamphodiacetate Drugs 0.000 abstract 1
- 229940080279 sodium cocoate Drugs 0.000 abstract 1
- 229940045870 sodium palmitate Drugs 0.000 abstract 1
- BGEBZHIAGXMEMV-UHFFFAOYSA-N 5-methoxypsoralen Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OC BGEBZHIAGXMEMV-UHFFFAOYSA-N 0.000 description 8
- YRAQEMCYCSSHJG-NSHDSACASA-N (S)-columbianetin Chemical compound C1=CC(=O)OC2=C1C=CC1=C2C[C@@H](C(C)(O)C)O1 YRAQEMCYCSSHJG-NSHDSACASA-N 0.000 description 7
- 235000013399 edible fruits Nutrition 0.000 description 7
- FFCDTHIJWHJUQJ-JZWAJAMXSA-N Edultin Chemical compound C1=CC(=O)OC2=C3[C@@H](OC(=O)C(\C)=C/C)[C@@H](C(C)(C)OC(C)=O)OC3=CC=C21 FFCDTHIJWHJUQJ-JZWAJAMXSA-N 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- DBMJZOMNXBSRED-UHFFFAOYSA-N Bergamottin Natural products O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)CCC=C(C)C DBMJZOMNXBSRED-UHFFFAOYSA-N 0.000 description 4
- GIJHDGJRTUSBJR-UHFFFAOYSA-N Bergaptol Natural products O1C(=O)C=CC2=C1C=C1OC=CC1=C2O GIJHDGJRTUSBJR-UHFFFAOYSA-N 0.000 description 4
- RNKZFOIQKCQOAQ-UHFFFAOYSA-N Isopimpinellin Natural products COC1CC(=O)Oc2c(OC)c3occc3cc12 RNKZFOIQKCQOAQ-UHFFFAOYSA-N 0.000 description 4
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- YXCORZFYRFZUOV-UHFFFAOYSA-N Xanthotoxol Natural products COc1c2OC(O)C=Cc2cc3ccoc13 YXCORZFYRFZUOV-UHFFFAOYSA-N 0.000 description 4
- 229960002045 bergapten Drugs 0.000 description 4
- KGZDKFWCIPZMRK-UHFFFAOYSA-N bergapten Natural products COC1C2=C(Cc3ccoc13)C=CC(=O)O2 KGZDKFWCIPZMRK-UHFFFAOYSA-N 0.000 description 4
- DFMAXQKDIGCMTL-UHFFFAOYSA-N isopimpinellin Chemical compound O1C(=O)C=CC2=C1C(OC)=C1OC=CC1=C2OC DFMAXQKDIGCMTL-UHFFFAOYSA-N 0.000 description 4
- 238000004898 kneading Methods 0.000 description 4
- 238000007493 shaping process Methods 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- JWVYQQGERKEAHW-UHFFFAOYSA-N xanthotoxol Chemical compound C1=CC(=O)OC2=C1C=C1C=COC1=C2O JWVYQQGERKEAHW-UHFFFAOYSA-N 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- IQTTZQQJJBEAIM-UHFFFAOYSA-N O-Acetyl-columbianetin Natural products C1=CC(=O)OC2=C1C=CC1=C2CC(C(C)(C)OC(=O)C)O1 IQTTZQQJJBEAIM-UHFFFAOYSA-N 0.000 description 3
- 244000296102 Selinum monnieri Species 0.000 description 3
- YRAQEMCYCSSHJG-UHFFFAOYSA-N Tetrahydro-oroselol Natural products C1=CC(=O)OC2=C1C=CC1=C2CC(C(C)(O)C)O1 YRAQEMCYCSSHJG-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- DQISGWRLCDLKJI-UHFFFAOYSA-N columbianetin Natural products C1=CC(=O)OC2=C(C(C(C(C)(O)C)O3)O)C3=CC=C21 DQISGWRLCDLKJI-UHFFFAOYSA-N 0.000 description 3
- IQTTZQQJJBEAIM-ZDUSSCGKSA-N columbianetin acetate Chemical compound C1=CC(=O)OC2=C1C=CC1=C2C[C@@H](C(C)(C)OC(=O)C)O1 IQTTZQQJJBEAIM-ZDUSSCGKSA-N 0.000 description 3
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- CRPUJAZIXJMDBK-BDAKNGLRSA-N (-)-camphene Chemical compound C1C[C@H]2C(=C)C(C)(C)[C@@H]1C2 CRPUJAZIXJMDBK-BDAKNGLRSA-N 0.000 description 2
- 229930006714 (-)-camphene Natural products 0.000 description 2
- DTGKSKDOIYIVQL-MRTMQBJTSA-N (-)-isoborneol Chemical compound C1C[C@@]2(C)[C@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-MRTMQBJTSA-N 0.000 description 2
- JBQHVGSHZLWWDC-AWEZNQCLSA-N 2-[(8S)-2-oxo-8,9-dihydrofuro[2,3-h]chromen-8-yl]propan-2-yl 2-methylpropanoate Chemical compound CC(C)C(=O)OC(C)(C)[C@@H]1Cc2c(O1)ccc1ccc(=O)oc21 JBQHVGSHZLWWDC-AWEZNQCLSA-N 0.000 description 2
- KPLBOWKEQXYXSD-UHFFFAOYSA-N Athamantin Natural products C1=CC(=O)OC2=C3C(OC(=O)CC(C)C)C(C(C)(C)OC(=O)CC(C)C)OC3=CC=C21 KPLBOWKEQXYXSD-UHFFFAOYSA-N 0.000 description 2
- JBQHVGSHZLWWDC-UHFFFAOYSA-N Cnidiadin Natural products C1=CC(=O)OC2=C1C=CC1=C2CC(C(C)(C)OC(=O)C(C)C)O1 JBQHVGSHZLWWDC-UHFFFAOYSA-N 0.000 description 2
- 241000125183 Crithmum maritimum Species 0.000 description 2
- 229940120146 EDTMP Drugs 0.000 description 2
- FFCDTHIJWHJUQJ-UHFFFAOYSA-N Gibanotin Natural products C1=CC(=O)OC2=C3C(OC(=O)C(C)=CC)C(C(C)(C)OC(C)=O)OC3=CC=C21 FFCDTHIJWHJUQJ-UHFFFAOYSA-N 0.000 description 2
- HPUXDMUGCAWDFW-UHFFFAOYSA-N Osthole Natural products COc1ccc2CCC(=O)Oc2c1C=CC(=O)C HPUXDMUGCAWDFW-UHFFFAOYSA-N 0.000 description 2
- KGEKLUUHTZCSIP-HOSYDEDBSA-N [(1s,4s,6r)-1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl] acetate Chemical compound C1C[C@]2(C)[C@H](OC(=O)C)C[C@H]1C2(C)C KGEKLUUHTZCSIP-HOSYDEDBSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- JRIBPWOXWIRQOQ-GHAIFCDISA-N columbianadin Chemical compound C1=CC(=O)OC2=C1C=CC1=C2C[C@@H](C(C)(C)OC(=O)C(\C)=C/C)O1 JRIBPWOXWIRQOQ-GHAIFCDISA-N 0.000 description 2
- XACHIBLJLSNFHL-UHFFFAOYSA-N columbianadin Natural products CC=C(C)/C(=O)OC(C)(C)C1CC2=C(O1)C=CC3C=CC(=O)OC23 XACHIBLJLSNFHL-UHFFFAOYSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- NFDRPXJGHKJRLJ-UHFFFAOYSA-N edtmp Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CCN(CP(O)(O)=O)CP(O)(O)=O NFDRPXJGHKJRLJ-UHFFFAOYSA-N 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- GWYFCOCPABKNJV-UHFFFAOYSA-M isovalerate Chemical compound CC(C)CC([O-])=O GWYFCOCPABKNJV-UHFFFAOYSA-M 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- MBRLOUHOWLUMFF-UHFFFAOYSA-N osthole Chemical compound C1=CC(=O)OC2=C(CC=C(C)C)C(OC)=CC=C21 MBRLOUHOWLUMFF-UHFFFAOYSA-N 0.000 description 2
- 235000019633 pungent taste Nutrition 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 239000004408 titanium dioxide Substances 0.000 description 2
- OHOTVSOGTVKXEL-WJXVXWFNSA-K trisodium;(2s)-2-[bis(carboxylatomethyl)amino]propanoate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)[C@H](C)N(CC([O-])=O)CC([O-])=O OHOTVSOGTVKXEL-WJXVXWFNSA-K 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- BPSYZMLXRKCSJY-UHFFFAOYSA-N 1,3,2-dioxaphosphepan-2-ium 2-oxide Chemical compound O=[P+]1OCCCCO1 BPSYZMLXRKCSJY-UHFFFAOYSA-N 0.000 description 1
- LIKMAJRDDDTEIG-UHFFFAOYSA-N 1-hexene Chemical compound CCCCC=C LIKMAJRDDDTEIG-UHFFFAOYSA-N 0.000 description 1
- XYHKNCXZYYTLRG-UHFFFAOYSA-N 1h-imidazole-2-carbaldehyde Chemical compound O=CC1=NC=CN1 XYHKNCXZYYTLRG-UHFFFAOYSA-N 0.000 description 1
- PRUMMFPRJSEJJL-UHFFFAOYSA-N 4-morpholin-4-yl-3-nitroaniline Chemical compound [O-][N+](=O)C1=CC(N)=CC=C1N1CCOCC1 PRUMMFPRJSEJJL-UHFFFAOYSA-N 0.000 description 1
- KDXVVZMYSLWJMA-UHFFFAOYSA-N Alloimperatorin Chemical compound O1C(=O)C=CC2=C1C(O)=C1OC=CC1=C2CC=C(C)C KDXVVZMYSLWJMA-UHFFFAOYSA-N 0.000 description 1
- BEYIWVKWKJROGZ-UHFFFAOYSA-N Alloimperatorin Natural products O1C(=O)C=CC2=C1C(O)=C1OC=CC1=C2OCC=C(C)C BEYIWVKWKJROGZ-UHFFFAOYSA-N 0.000 description 1
- 244000061520 Angelica archangelica Species 0.000 description 1
- RVGGCRQPGKFZDS-ODRFPHDWSA-N Archangelicin Natural products O=C(OC(C)(C)[C@@H]1[C@H](OC(=O)/C(=C/C)/C)c2c3OC(=O)C=Cc3ccc2O1)/C(=C/C)/C RVGGCRQPGKFZDS-ODRFPHDWSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000212948 Cnidium Species 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- RPNUMPOLZDHAAY-UHFFFAOYSA-N Diethylenetriamine Chemical compound NCCNCCN RPNUMPOLZDHAAY-UHFFFAOYSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical group [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- MPYYVGIJHREDBO-UHFFFAOYSA-N Isovaleriansaeure-isobornylester Natural products C1CC2(C)C(OC(=O)CC(C)C)CC1C2(C)C MPYYVGIJHREDBO-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 241001647091 Saxifraga granulata Species 0.000 description 1
- 235000019084 Selinum monnieri Nutrition 0.000 description 1
- 206010040914 Skin reaction Diseases 0.000 description 1
- 208000007074 Trichomonas Vaginitis Diseases 0.000 description 1
- 208000025206 Trichomonas vaginitis urogenital infection Diseases 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- RVGGCRQPGKFZDS-AKRYRNCVSA-N [(8s,9r)-8-[2-[(z)-2-methylbut-2-enoyl]oxypropan-2-yl]-2-oxo-8,9-dihydrofuro[2,3-h]chromen-9-yl] (z)-2-methylbut-2-enoate Chemical compound C1=CC(=O)OC2=C3[C@@H](OC(=O)C(\C)=C/C)[C@@H](C(C)(C)OC(=O)C(\C)=C/C)OC3=CC=C21 RVGGCRQPGKFZDS-AKRYRNCVSA-N 0.000 description 1
- QILXPCHTWXAUHE-UHFFFAOYSA-N [Na].NCCN Chemical compound [Na].NCCN QILXPCHTWXAUHE-UHFFFAOYSA-N 0.000 description 1
- OQRDSLOUOFIGSC-UHFFFAOYSA-N [Na].[Na].[Na].[Na].[Na].NCCNCCN Chemical compound [Na].[Na].[Na].[Na].[Na].NCCNCCN OQRDSLOUOFIGSC-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 125000004423 acyloxy group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 229940076810 beta sitosterol Drugs 0.000 description 1
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 1
- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- ZFXVRMSLJDYJCH-UHFFFAOYSA-N calcium magnesium Chemical compound [Mg].[Ca] ZFXVRMSLJDYJCH-UHFFFAOYSA-N 0.000 description 1
- 238000006757 chemical reactions by type Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- RWIGWWBLTJLKMK-UHFFFAOYSA-N diethoxyphosphorylmethanol Chemical compound CCOP(=O)(CO)OCC RWIGWWBLTJLKMK-UHFFFAOYSA-N 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000019439 ethyl acetate Nutrition 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000004345 fruit ripening Effects 0.000 description 1
- 239000008233 hard water Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- OLOOJGVNMBJLLR-UHFFFAOYSA-N imperatorin Chemical compound C1=CC(=O)OC2=C1C=C1C=COC1=C2OCC=C(C)C OLOOJGVNMBJLLR-UHFFFAOYSA-N 0.000 description 1
- XKVWLLRDBHAWBL-UHFFFAOYSA-N imperatorin Natural products CC(=CCOc1c2OCCc2cc3C=CC(=O)Oc13)C XKVWLLRDBHAWBL-UHFFFAOYSA-N 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- HPEUEJRPDGMIMY-IFQPEPLCSA-N molybdopterin Chemical compound O([C@H]1N2)[C@H](COP(O)(O)=O)C(S)=C(S)[C@@H]1NC1=C2N=C(N)NC1=O HPEUEJRPDGMIMY-IFQPEPLCSA-N 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000009919 sequestration Effects 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 230000035483 skin reaction Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- WHNXAQZPEBNFBC-UHFFFAOYSA-K trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(2-hydroxyethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].OCCN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O WHNXAQZPEBNFBC-UHFFFAOYSA-K 0.000 description 1
- FHGJYTNPLCNRLG-UHFFFAOYSA-K trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(2-hydroxyethyl)amino]acetate;hydrate Chemical compound O.[Na+].[Na+].[Na+].OCCN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O FHGJYTNPLCNRLG-UHFFFAOYSA-K 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a fructus cnidii inflammation diminishing compound perfumed soap which is prepared from the following raw materials in parts by weight: 0.05-0.15 parts of a fructus cnidii extract, 15-25 parts of sodium cocoate, 50-70 parts of sodium palmitate, 3-5 parts of amino betaine cocoamphopropinate, 3-5 parts of disodium cocoamphodiacetate and 20 parts of water. The fructus cnidii inflammation diminishing compound perfumed soap disclosed by the invention is fine and stable in foam, mild in performance and low in irritation to skin, and can be used for diminishing inflammation and sterilizing after being especially added with the fructus cnidii extract.
Description
Technical field:
The present invention relates to a kind of perfumed soap, particularly a kind of Fructus Cnidii anti-inflammatory composite soap.
Background technology:
Perfumed soap (soap) is one of skin, hair washing and nursing article, is a kind of daily necessities.Perfumed soap is with sodium soap and other tensio-active agents for main raw material, adds quality improver and appearance modifying agents, the product made after machine-shaping.
Perfumed soap is requisite washing and nursing article in daily life, with sodium soap and other tensio-active agents for main raw material, adds quality improver and appearance modifying agents, the product made after machine-shaping.The function of perfumed soap is clean washing, to be used in above skin that yes removes earth dirt, skin secretion, movement, chemical substance or bacterium etc., in the today stressing cosmetic result, removing the makeup of skin surface, skin care products or medicine is also one of its main purposes.
In the prior art, the Cake-shape soap of the many insights of perfumed soap to be fatty acid sodium salt be soap base, although have good cleaning force, whipability and easy washability, but not resistance to hard water, can produce incrustation scale during washing, form calcium magnesium soap, degreasing power is strong, the soap of human body life-time service meta-alkalescence can make skin feel dry and astringent, has excitement.
Fructus Cnidii, another name Daucus carota L. is samphire cnidium monnieri Cnidium monnieri(L.) dry mature fruit of Cuss..Gather when summer, autumn two season fruit maturation, removing impurity, dries.Nature and flavor: warm in nature, taste is pungent, bitter.Function cures mainly: warming the kidney to invigorate YANG, and eliminating dampness is dispeled the wind, desinsection.For under impotence, Gong Leng, cold-dampness band, arthritis with fixed pain caused by dampness pain in the back; Control vulval eczema, married woman's pruritus vulvae, trichomonal vaginitis outward.
Chemical composition of Chinese materia medica: fruit is containing volatile oil 1.3%, and main component is firpene (l-Pine-ne), amphene (l-Camphene), different one-tenth acid borneol acetate (Bornyl isovale-rate), isocamphol (Isoborneol).Again containing Osthole (Ostho-le), cnidimine (Cnidimine, i.e. Edultin), different saxifrage case (IsoPiBrpinelline), bergapton, columbianetin (Dihydroo-roselol, Columbianetin) and angelate (ColuInbianadin), acetic ester (o-Acetyl columbianetin); Mouth isopentanoate, cnidiadin (Cnidiadiu), isobutyl acyloxy o-acetylcolumbianetin.Root is containing cnidium monnieri cloudy element, Isopimpinellin, alloimperatorin (Alloimperatorine), xanthotoxol (Xanthotoxol), ammidin (Imperatorine).Fruit is containing volatile oil about 1.3%, and wherein principal constituent is 1 firpene (l-pinene), 1-amphene (l-camphene), isovaleric acid borneol acetate (bornylisovalerare) and 7-Osthole (osthole) etc.From fruit alcohol extract except obtaining 7-Osthole, still obtain palmitinic acid (palmitic acid)), β-sitosterol, bergapten (bergapten), Isopimpinellin (isopimpinellin) and xanthotoxol (xanthotoxol) etc.It is reported, Chinese commodity Fructus Cnidii fruit is containing columbianadin (columbianadin) 0.20%, circle root of Dahurain angelica element (archangelicin), cnidimine (edultin), bergapten, Isopimpinellin, O-acetyl Columbianedin (O-acetyl-columbianetin), Columbianedin (columbianetin), O-isovaleryl Columbianedin (O-islvaleryl-columbianetin), 3'-isobutyl acyl-oxygen-O-acetyl Columbianedin (3'-isobutyloxy-O-acetylcolumbianetin) and O-isobutyryl Columbianedin (O-isobutylcolumbianetin, cnidiadin).Seed is containing bergapten, Europe orecselon (orosclol) and cnidimine.
Summary of the invention:
For prior art above shortcomings, technical problem to be solved by this invention is to provide a kind of Fructus Cnidii anti-inflammatory composite soap.
Technical problem of the present invention, is achieved by following technical proposals:
A kind of Fructus Cnidii anti-inflammatory composite soap, comprises the raw material of following weight part: Fructus cnidii extract 0.05-0.15 part, coconut oil sodium 15-25 part, Sodium pentadecanecarboxylate 50-70 part, coco betaine amide group both sexes base propionic salt 3-5 part, cocounut oil acyl both sexes base oxalic acid disodium 3-5 part, 20 parts, water.
Preferably, a kind of Fructus Cnidii anti-inflammatory composite soap, comprise the raw material of following weight part: Fructus cnidii extract 0.05-0.15 part, sequestrant 0.5-1.5 part, coco betaine amide group both sexes base propionic salt 3-5 part, cocounut oil acyl both sexes base oxalic acid disodium 3-5 part, coconut oil sodium 15-25 part, Sodium pentadecanecarboxylate 50-70 part, 20 parts, water.
Described sequestrant is disodium EDTA, tetrasodium salt of EDTA, ethylenediamine tetramethylene phosphonic acid, hydroxymethyl phosphonic acid diethyl ester, diethylenetriamine penta sodium, hexapotassium, two hexene triamine five methylenephosphonic acids, diethylenetriamine pentamethylenophosphonic acid(DTPP) seven sodium salt, EDTMP six sodium salt, sodium ethylenediamine tetramethylenephosphonate, one in methyl-glycine diacetate tri-sodium and hydroxyethyl diamine tetraacethyl trisodium salt or its mixture.
Optimally, described sequestrant, is made up of by weight following component: methyl-glycine diacetate tri-sodium 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
Below, simple declaration is made to part material involved in the present invention:
Fructus Cnidii English name: Fructus Cnidii (drawing); Common cnidium fruit defines: the dry mature fruit of samphire cnidium monnieri Cnidium monnieri (L.) Cuss..Fructus cnidii extract of the present invention can pass through commercially available and obtain, as the Fructus cnidii extract that Shenzhen BoDun spice Co., Ltd produces.This Fructus cnidii extract also can adopt following method prepare and obtain: after Fructus Cnidii is pulverized, add the deionized water of 6-10 times of weight, soak 1-3 hour, ultrasonic extraction 10-15 minute, filter, centrifugal, discard precipitation by supernatant concentration, obtained Fructus cnidii extract, controls Fructus cnidii extract density at 1.05g/cm
3left and right.
Coco betaine amide group both sexes base propionic salt, CAS accession number: 100085-64-1.
Cocounut oil acyl both sexes base oxalic acid disodium, CAS accession number: 68650-39-5.
Described methyl-glycine diacetate tri-sodium, CAS accession number: 170492-24-7, its English name: L-Alanine, N, N-bis (carboxymethyl)-, sodium salt (1:3).It has better biological degradability than conventional sequestrant EDTA, NTA, and under wider PH scope and high temperature, more stable, have higher calcium sequestration capacity, and have higher solubility property to inorganic sediment, heavy metal has good sequestering power.BASF AG is selected to produce in the present invention
.
Described hydroxyethyl diamine tetraacethyl trisodium salt, CAS accession number: 207386-87-6, its English name: Glycine, N-[2-[bis (carboxymethyl) amino] ethyl]-N-(2-hydroxyethyl)-, trisodium salt, hydrate (9CI).
In addition, in the present invention, other functional ingredient conventional in conventional toilet soaps can also be added, such as: antiseptic-germicide, pigment, essence, oxidation inhibitor, titanium dioxide etc., to realize corresponding function respectively.As added antiseptic-germicide, the antioxidant of 0.05-0.20 weight part, the sanitas of 0.02-0.2 weight part of 0.2-0.8 weight part on formula basis of the present invention, the essence of the titanium dioxide of 0.02-2 weight part, the white dyes of 0.001-0.05 weight part or 0.2-1.2 weight part.
Fructus Cnidii anti-inflammatory composite soap of the present invention can adopt the general soapmaking step of industry conventional toilet soaps to be prepared, as:
A () kneads spice: taken in proportion in the kneading machine joining conventional soapmaking by the various raw materials of said components, knead and be uniformly mixed.
B () grinds: the material after being uniformly mixed kneading, enters in shredder, carries out soap body grinding.
(c) vacuum press strip: by the soap body after grinding, enter vacuum plodder, carry out vacuum press strip.
D () prints: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains shaping soap body.
Fructus Cnidii anti-inflammatory composite soap of the present invention, foam exquisiteness is stable, and performance is gentle, low to the pungency of skin, after special interpolation Fructus cnidii extract, more can anti-inflammation and sterilization.Especially, stronger killing action is had to trichomonas vaginitis.
Embodiment:
Embodiment further illustrates of the present invention below, instead of limit the scope of the invention.In the present invention, if no special instructions, each raw material all in working substance content for 100%.
Embodiment 1
Each raw material is taken by embodiment 1 data of table 1 correspondence.
A () kneads spice: joined in soap kneading machine by various raw material, knead and be uniformly mixed.
B () grinds: the material after being uniformly mixed kneading, enters in shredder, carries out soap body grinding.
(c) vacuum press strip: by the soap body after grinding, enter vacuum plodder, carry out vacuum press strip.
D () prints: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains shaping soap body.
Embodiment 2
Each raw material is taken by embodiment 2 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Embodiment 3
Each raw material is taken by embodiment 3 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Embodiment 4
Each raw material is taken by embodiment 4 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Comparative example 1
Each raw material is taken by comparative example 1 data of table 1 correspondence.Perfumed soap is prepared by the method for embodiment 1.
Table 1: fancy soap formula list position: kilogram
Test case 1:
Experiment soap lye concentration is 5wt%, and when consumption is 0.3ml, by HET VAM measurements determination skin reaction classification (relative values classification), intense stimulus > 2.0, stimulates 1.2-2.0, medium stimulation 0.8-1.2, minimal irritation 0.0-0.8.
Use Roche Latherometer to carry out foaming properties test, soap lye concentration is 2.5wt%, tests the foam height of 0 minute and 5 minutes respectively.
Table 2: test data table
The test data of experiment of associative list 2, the present invention selects coco betaine amide group both sexes base propionic salt and cocounut oil acyl both sexes base oxalic acid disodium built-up soap fundamental mode anion surfactant coconut oil sodium and Sodium pentadecanecarboxylate initiatively, effectively can reduce the pungency of perfumed soap; Select the composite interpolation of sequestrant methyl-glycine diacetate tri-sodium and hydroxyethyl diamine tetraacethyl trisodium salt initiatively, foaming power and the foam stability of perfumed soap can be promoted further.Above-mentioned difference technical characteristic did not have open in the prior art, was not common practise yet.
Claims (1)
1. a Fructus Cnidii anti-inflammatory composite soap, it is characterized in that, comprise the raw material of following weight part: Fructus cnidii extract 0.05-0.15 part, sequestrant 0.5-1.5 part, coco betaine amide group both sexes base propionic salt 3-5 part, cocounut oil acyl both sexes base oxalic acid disodium 3-5 part, coconut oil sodium 15-25 part, Sodium pentadecanecarboxylate 50-70 part, 20 parts, water, described sequestrant, is made up of by weight following component: methyl-glycine diacetate tri-sodium 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310193043.1A CN103361209B (en) | 2013-05-22 | 2013-05-22 | Fructus cnidii inflammation diminishing compound perfumed soap |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310193043.1A CN103361209B (en) | 2013-05-22 | 2013-05-22 | Fructus cnidii inflammation diminishing compound perfumed soap |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103361209A CN103361209A (en) | 2013-10-23 |
| CN103361209B true CN103361209B (en) | 2014-12-17 |
Family
ID=49363479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310193043.1A Active CN103361209B (en) | 2013-05-22 | 2013-05-22 | Fructus cnidii inflammation diminishing compound perfumed soap |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103361209B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104263569B (en) * | 2014-10-14 | 2017-10-20 | 淄博职业学院 | A kind of centipedaplant herb anti-inflammatory perfumed soap and preparation method thereof |
| CN105462727A (en) * | 2015-12-11 | 2016-04-06 | 梁文成 | Wormwood mixed soap |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743395A (en) * | 1986-09-12 | 1988-05-10 | The Drackett Company | Thickened acid cleaner compositions containing quaternary ammonium germicides and having improved thermal stability |
| CN1050381C (en) * | 1995-05-18 | 2000-03-15 | 高秀云 | Functional perfumed soap made from traditional Chinese herbal medicines |
| CN100547063C (en) * | 2006-08-22 | 2009-10-07 | 乔爱娴 | Semen Litchi extract is killed application in the soap of acarid in preparation |
| CN102363740B (en) * | 2010-12-10 | 2012-09-12 | 江南大学 | Low-irritation and high-foaminess fancy soap formula |
-
2013
- 2013-05-22 CN CN201310193043.1A patent/CN103361209B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103361209A (en) | 2013-10-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2013131307A1 (en) | Transparent beauty soap composition | |
| JP2011153167A (en) | Detergent | |
| CN103387894B (en) | Beautifying gynostemma pentaphylla composite perfumed soap | |
| CN104173250B (en) | Skin-nourishing liquid soap containing natural bacteriostatic components and preparation method thereof | |
| CN105476950B (en) | Moisturizing foam mildy wash and preparation method thereof | |
| CN103194340B (en) | Bacteria resisting amur corktree bark compound soap | |
| CN103361209B (en) | Fructus cnidii inflammation diminishing compound perfumed soap | |
| CN103361211B (en) | Mint cool and refreshing compound perfumed soap | |
| CN103194342B (en) | Skin whitening platycodon root compound soap | |
| CN103361213B (en) | Asparagus fern whitening compound perfumed soap | |
| CN103666886B (en) | Pseudo-ginseng low-irritation skin care soap | |
| KR101395218B1 (en) | Soap comprising wood-cultivated ginseng and manufacturing method thereof | |
| KR100862586B1 (en) | Preparation method of extracts from and soap with sulfur salts produced the Himalayas | |
| CN103361212B (en) | Selfheal revitalizing compound perfumed soap | |
| CN103361199B (en) | Body odor removing rhizoma alismatis composite fancy soap | |
| CN103387896B (en) | Ginkgo leaf whitening composite perfumed soap | |
| CN103666885B (en) | Herba rhodiolae low-irritation skincare fancy soap | |
| CN103666888B (en) | Dandelion low-irritation skincare perfumed soap | |
| CN103666884B (en) | Sanguisorba antibacterial compound soap | |
| CN103361210B (en) | Rehmannia oil-inhibiting compound perfumed soap | |
| JP2004284964A (en) | Solid detergent | |
| CN103695215B (en) | Licorice low-irritation skin-care perfumed soap | |
| CN103387895B (en) | Kudzu vine root nourishing composite perfumed soap | |
| CN107441001B (en) | A method of hand cleanser is prepared using ginger and camellia seed | |
| CN103194341B (en) | Low-irritation baical skullcap root skin care soap |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Pan Tingbo Inventor after: Yao Jianfeng Inventor after: Wang Ya Inventor after: Zhang Xiaoping Inventor before: Huang Meirong |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: HUANG MEIRONG TO: PAN TINGBO YAO JIANFENG WANG YA ZHANG XIAOPING |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20181218 Address after: 201111 E2128 first, 5500 Yuanjiang Road, Minhang District, Shanghai. Patentee after: Shanghai Yanzi Chemical Technology Co., Ltd. Address before: 201604 219, room 2, Lane 1000, Tower Road, Shek Hu Town, Songjiang District, Shanghai Patentee before: Shanghai Bafang Fine Chemical Engineering Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190919 Address after: 233010 Incubation Workshop, 414 Changle Road, Yuhui District, Bengbu City, Anhui Province Patentee after: Bengbu Xingshi Intellectual Property Operations Co., Ltd. Address before: 201111 Shanghai city Minhang District Yuanjiang Road No. 5500 building first room E2128 Patentee before: Shanghai Yanzi Chemical Technology Co., Ltd. |