CN103349690A - Comprehensive lactation-promotion medicine and preparation method thereof - Google Patents
Comprehensive lactation-promotion medicine and preparation method thereof Download PDFInfo
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- CN103349690A CN103349690A CN2013102326881A CN201310232688A CN103349690A CN 103349690 A CN103349690 A CN 103349690A CN 2013102326881 A CN2013102326881 A CN 2013102326881A CN 201310232688 A CN201310232688 A CN 201310232688A CN 103349690 A CN103349690 A CN 103349690A
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Abstract
The invention relates to a lactation-promotion medicine and a preparation method thereof. The medicine is prepared from Mongolian milkvetch root, red ginseng, banksian rose, common jujube, rice paper plant pith, cowherb seed, pangolin, Chinese thorowax root, white peony root, largehead atractylodes rhizome, ligusticum, and licorice root. The medicine is prepared according to a specific ratio. Through the steps of high-temperature leaching, filtering, heating and concentration, soft material preparation, granulation, drying, screening, packaging, and the like, instant granules are obtained. The medicine provides a comprehensive effect of qi nourishing, blood nourishing, liver soothing, and qi depression relieving. The medicine has a good lactation-promotion effect. With an average of 3 months of administration, milk secretion is adequate, and is enough for 12-18 months of feeding. The medicine is safe and reliable to human body.
Description
Technical field
The present invention relates to the medicinal preparation field of animals and plants material, particularly a kind of Lactogenic medicine and preparation method thereof.
Background technology
Studies show that the breast milk comprehensive nutrition, the required various materials of infants growth and development are not only arranged, and be easy to digest and assimilate, in breast milk, also contain many immune factors, the baby can improve immunity after absorbing.Breast milk is best Infants'feeding product, and in addition, breast milk also has special effect to baby's immunity and psychology, and as seen, breast milk plays vital effect to neonatal growth.
Yet, the puerpera tends to occur symptom on some healths in puerperal, for the thin puerpera of some bodies, because postpartum hemorrhage is too much, cause puerpera's QI and blood deficiency, be embodied in degradation symptom under weak, pale complexion, hyperhidrosis, the appetite, after this has affected puerpera's production, the change of milk is given birth to, and causes puerpera's milk seldom, even does not have.For the puerpera of QI and blood deficiency, need to adopt the qi and blood tonifying method, promote the change of puerpera's milk to give birth to.
For the partially fat puerpera of some bodily forms, puerperal occurs the stagnation of QI due to depression of the liver symptom in addition, lose blood puerperal lessly although be embodied in, have rosy cheeks, the appetite extreme difference, with dyspepsia, depressed emotion, functional activity of QI being not smooth, this change that can affect equally milk is given birth to.For the puerpera of this class stagnation of QI due to depression of the liver, need to adopt the dispersing the stagnated live-QI to relieve the stagnation of QI method, reach the effect of lactogenic.
For other puerperas, the comprehensive symptom of QI and blood deficiency and stagnation of QI due to depression of the liver then can appear, and the change that has influence on puerpera's milk is given birth to.One of them reason is: puerperal QI and blood deficiency, cause puerpera's inappetence, depressed, melancholy for a long time, caused at last functional activity of QI being not smooth, stagnation of QI due to depression of the liver.At this time, solely adopt the qi and blood tonifying method, perhaps the dispersing the stagnated live-QI to relieve the stagnation of QI method is come the puerpera is nursed one's health, and does not have very good effect.
Summary of the invention
Technical problem to be solved by this invention is: the puerpera produces rear appearance, the symptomes complice of QI and blood deficiency and stagnation of QI due to depression of the liver, the change that has influence on puerpera's milk is given birth to, and solely adopts the qi and blood tonifying method, perhaps the dispersing the stagnated live-QI to relieve the stagnation of QI method is come the puerpera is nursed one's health, and does not have very good effect.
For solving this technical problem: the technical solution used in the present invention is:
The invention provides a kind of Lactogenic medicine, this medicine helps, and the QI and blood deficiency that the conditioning puerpera causes puerperal and the symptomes complice of stagnation of QI due to depression of the liver play the effect that good promotion milkization is given birth to, and the composition of this Lactogenic medicine is counted by weight
9.5～10.5 parts in 38～42 parts of the Radixs Astragali, 19～21 parts of Radix Ginseng Rubra, 4.5～5.5 parts of the Radix Aucklandiae, 28.5～31.5 parts in Fructus Jujubae, 9.5～10.5 parts of Medulla Tetrapanaciss, 28.5～31.5 parts of Semen Vaccariae (stir-fry), 14～16 parts of Squama Maniss (cannon), 9.5～10.5 parts of Radix Bupleuri, 19～21 parts of the Radix Paeoniae Albas, 19～21 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 19～21 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae
As preferably: the composition of Lactogenic medicine, count by weight: 10 parts in 40 parts of the Radixs Astragali, 20 parts of Radix Ginseng Rubra, 5 parts of the Radix Aucklandiae, 30 parts in Fructus Jujubae, 10 parts of Medulla Tetrapanaciss, 30 parts of Semen Vaccariae (stir-fry), 15 parts of Squama Maniss (cannon), 10 parts of Radix Bupleuri, 20 parts of the Radix Paeoniae Albas, 20 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 20 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae
Above-described raw material all needs the measured Chinese medicine of matter, can not use succedaneum.
This Lactogenic medicine is said solid preparation on the pharmaceutics, specifically, is dissolved granule.
The present invention also provides a kind of preparation method of said medicine dissolved granule, specifically has the following steps
(1) preparation of raw material: take by weighing by weight the raw material Radix Astragali, Radix Ginseng Rubra, the Radix Aucklandiae, Fructus Jujubae, Medulla Tetrapanacis, Semen Vaccariae (stir-fry), Squama Manis (cannon), Radix Bupleuri, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Angelicae Sinensis and Radix Glycyrrhizae, put into extractor and mix, the water soaking of 5-20 times of amounts of adding 30 minutes;
(2) high-temp extracting and filtration: the raw material for preparing in the heating decoction step (1) 2-3 hours, the leaching decocting liquid, its slag adds the water of 5-10 times of amounts again, heating decocted 1.5-2 hours, the leaching decocting liquid, add the water of 4-6 times of amounts toward its slag, heating decocted 1-1.5 hours again, merged these three gained filtrates after filtering;
(3) heating is concentrated: with the filtrate of the last gained of step (2), heating is concentrated into the thick paste shape, makes moisture be down to 28-31%;
(4) make soft material: with the thick paste of step (3) gained, add the starch of 2.5-3.5 times of volumes, stir, and then add volume ratio and account for 70-90% ethanol, stir into uniform soft material;
(5) granulating is dry: the soft material that step (4) is obtained, through 12 mesh sieve granulations, again with the gained granule in 60-90 ℃ of Uniform Ventilation dryings;
(6) screening granule: with the granule of step (5) gained; screen through 12 mesh sieves; after the suitable pulverizing of the granule of sifting out; again screen through 12 mesh sieves again; after granule under twice screening gathered, remove wherein fine powder with 40 mesh sieves sieve again, obtain finished product electuary granule; the granule by 12 mesh sieves and can be used for the production of next batch by the dust of 40 mesh sieves is not used for regulating the humidity of soft material.
(7) pack: by quantitatively the electuary granule being packed of every bag.
Be diagnosed as and suffer from the syndromic of QI and blood deficiency and stagnation of QI due to depression of the liver, hypogalactia type puerpera (in 24 hours puerperal, namely diagnosable go out the result), can within 24-36 hours puerperal, begin to take lactagogue of the present invention, one day 3 times, a 10g, 7 days is a course for the treatment of
When taking Lactogenic medicine electuary of the present invention, taboo and tobacco and wine, the mixed clothes of numb, peppery, living, cold food;
When taking Lactogenic medicine electuary of the present invention, various Western medicine are taken in taboo;
The puerpera suffers from during the other diseases, forbids taking;
Take a period of time, after milk is unimpeded, need timing with the milk sucking-off, guarantee unblocked.
The invention has the beneficial effects as follows: lactagogue of the present invention is safe and reliable, and instructions of taking is simple, has the comprehensive function of qi and blood tonifying and dispersing the stagnated live-QI to relieve the stagnation of QI, and the mechanism of action of medicine can promote the hypertrophy second time of mammary glandular cell to grow, and produces good lactogenic effect.
The specific embodiment
Embodiment 1:
In the present embodiment, the composition of Lactogenic medicine is counted: 10.5 parts in 38 parts of the Radixs Astragali, 21 parts of Radix Ginseng Rubra, 4.5 parts of the Radix Aucklandiae, 28.5 parts in Fructus Jujubae, 10.5 parts of Medulla Tetrapanaciss, 31.5 parts of Semen Vaccariae (stir-fry), 14 parts of Squama Maniss (cannon), 10.5 parts of Radix Bupleuri, 21 parts of the Radix Paeoniae Albas, 21 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 19 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae by weight.
The preparation method of dissolved granule is as described in the description.
Embodiment 2:
In the present embodiment, the composition of Lactogenic medicine is counted: 10 parts in 40 parts of the Radixs Astragali, 20 parts of Radix Ginseng Rubra, 5 parts of the Radix Aucklandiae, 30 parts in Fructus Jujubae, 10 parts of Medulla Tetrapanaciss, 30 parts of Semen Vaccariae (stir-fry), 15 parts of Squama Maniss (cannon), 10 parts of Radix Bupleuri, 20 parts of the Radix Paeoniae Albas, 20 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 20 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae by weight.
The preparation method of dissolved granule is as described in the description.
Embodiment 3:
In the present embodiment, the composition of Lactogenic medicine is counted: 9.5 parts in 42 parts of the Radixs Astragali, 19 parts of Radix Ginseng Rubra, 5.5 parts of the Radix Aucklandiae, 31.5 parts in Fructus Jujubae, 9.5 parts of Medulla Tetrapanaciss, 28.5 parts of Semen Vaccariae (stir-fry), 16 parts of Squama Maniss (cannon), 9.5 parts of Radix Bupleuri, 19 parts of the Radix Paeoniae Albas, 19 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 21 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae by weight.
The preparation method of dissolved granule is as described in the description.
In order to verify the actual effect of medicine of the present invention, the hypogalactia puerpera who 240 routine inventors is participated in person clinical treatment has done clinical trial, and these 240 puerperas are diagnosed as the symptomes complice of suffering from QI and blood deficiency and stagnation of QI due to depression of the liver puerperal.
240 puerperas are divided into 4 groups at random, are respectively A group, B group, C group, D group, every group of 60 people,
These 3 groups of A, B, C took respectively the Lactogenic medicine dissolved granule of embodiment 1, embodiment 2 and embodiment 3 36 hours puerperal, and one day 3 times, a 10g, 7 days is a course for the treatment of; The D group is group in contrast, accepts the Primary Care of conventional obstetrics.
Therapeutic effect is formulated clinical observation according to " traditional Chinese medical science medical diagnosis on disease criterion of therapeutical effect " and " new drug (Chinese medicine) guideline of clinical investigations ":
(1) clinical criteria: puerperal hypogalactia is women's postpartum breastfeeding phase, the galactopoiesis amount few or completely without, can not satisfy the needs of feeding infant.
(2) tcm syndrome standard:
QI and blood deficiency: puerperal breast is few, very less or completely without, milk is rare clearly, without swollen sense.Companion's lustreless complexion, mental fatigue with loss of appetite.Light red tongue, few tongue, deficient and thready pulse.
Stagnation of QI due to depression of the liver: puerperal breast is few, very less or completely without, distending pain of the breast or slight fever.The breast side of body is unhappy.Irritated at heart, diet reduces, tongue fur BOHUANG, stringy pulse.
(3) curative effect judging standard:
Produce effects: galactopoiesis increases, but inadequate feeding infant;
Effectively: galactopoiesis is more, but still inadequate feeding infant;
Good effect: galactopoiesis is a lot, can normally feed the baby;
Invalid: galactopoiesis is without change.
Take the puerpera of drug particles electuary of the present invention, after having taken a course for the treatment of, the transference cure of deficient qi and blood and stagnation of QI due to depression of the liver, tongue fur and pulse condition recover normal, and complexion is improved, and appetite increases, and milk increases, and mammary gland protuberance degree increases gradually.
Come Estimating curative effect by taking a galactopoiesis amount after the course for the treatment of, specifically as described in the table 1-4:
60 routine maternity clothings are added up with the curative effect behind the lactagogue dissolved granule of embodiment 1 in the table 1A group
60 routine maternity clothings are added up with the curative effect behind the lactagogue dissolved granule of embodiment 2 in the table 2B group
60 routine maternity clothings are added up with the curative effect behind the lactagogue dissolved granule of embodiment 3 in the table 3C group
60 routine puerperas accept the curative effect statistics after the Primary Care of conventional obstetrics in the table 4D group
For 180 puerperas that take lactagogue of the present invention, effect occurred taking in 1-3 days afterwards, reached remarkable result in 4-6 days taking, puerpera's QI and blood is sufficient, and milk obviously increases, and breast is full, produce the swelling sense, after 7 days, the transference cure of QI and blood deficiency and stagnation of QI due to depression of the liver.
For 180 puerperas that take lactagogue of the present invention, take 3 courses for the treatment of after, galactopoiesis is sufficient, enough baby clothes are with breast milk more than 1 year.Take above-mentioned 180 puerperas of lactagogue of the present invention, not yet find the generation of a routine breast carcinoma case, as seen this medicine is safe and reliable.
Claims (5)
1. comprehensive Lactogenic medicine is characterized in that: the composition of described Lactogenic medicine, count by weight
9.5～10.5 parts in 38～42 parts of the Radixs Astragali, 19～21 parts of Radix Ginseng Rubra, 4.5～5.5 parts of the Radix Aucklandiae, 28.5～31.5 parts in Fructus Jujubae, 9.5～10.5 parts of Medulla Tetrapanaciss, 28.5～31.5 parts of Semen Vaccariae (stir-fry), 14～16 parts of Squama Maniss (cannon), 9.5～10.5 parts of Radix Bupleuri, 19～21 parts of the Radix Paeoniae Albas, 19～21 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 19～21 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae.
2. Lactogenic medicine as claimed in claim 1 is characterized in that: the composition of described Lactogenic medicine, count by weight
10 parts in 40 parts of the Radixs Astragali, 20 parts of Radix Ginseng Rubra, 5 parts of the Radix Aucklandiae, 30 parts in Fructus Jujubae, 10 parts of Medulla Tetrapanaciss, 30 parts of Semen Vaccariae (stir-fry), 15 parts of Squama Maniss (cannon), 10 parts of Radix Bupleuri, 20 parts of the Radix Paeoniae Albas, 20 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 20 parts of Radix Angelicae Sinensis and Radix Glycyrrhizae.
3. Lactogenic medicine as claimed in claim 1, it is characterized in that: described Lactogenic medicine is said solid preparation on the pharmaceutics.
4. Lactogenic medicine as claimed in claim 3, it is characterized in that: described Lactogenic medicine is dissolved granule.
5. such as the preparation method of each described Lactogenic medicine of claim 1 to 4, it is characterized in that: said method comprising the steps of:
(1) preparation of raw material: take by weighing by weight the raw material Radix Astragali, Radix Ginseng Rubra, the Radix Aucklandiae, Fructus Jujubae, Medulla Tetrapanacis, Semen Vaccariae (stir-fry), Squama Manis (cannon), Radix Bupleuri, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Angelicae Sinensis and Radix Glycyrrhizae, put into extractor and mix, the water soaking of 5-20 times of amounts of adding 30 minutes;
(2) high-temp extracting and filtration: the raw material for preparing in the heating decoction step (1) 2-3 hours, the leaching decocting liquid, its slag adds the water of 5-10 times of amounts again, heating decocted 1.5-2 hours, the leaching decocting liquid, add the water of 4-6 times of amounts toward its slag, heating decocted 1-1.5 hours again, merged these three gained filtrates after filtering;
(3) heating is concentrated: with the filtrate of the last gained of step (2), heating is concentrated into the thick paste shape, makes moisture be down to 28-31%;
(4) make soft material: with the thick paste of step (3) gained, add the starch of 2.5-3.5 times of volumes, stir, and then add volume ratio and account for 70-90% ethanol, stir into uniform soft material;
(5) granulating is dry: the soft material that step (4) is obtained, through 12 mesh sieve granulations, again with the gained granule in 60-90 ℃ of Uniform Ventilation dryings;
(6) screening granule: with the granule of step (5) gained; screen through 12 mesh sieves; after the suitable pulverizing of the granule of sifting out; again screen through 12 mesh sieves again; after granule under twice screening gathered, remove wherein fine powder with 40 mesh sieves sieve again, obtain finished product electuary granule; the granule by 12 mesh sieves and can be used for the production of next batch by the dust of 40 mesh sieves is not used for regulating the humidity of soft material.
(7) pack: by quantitatively the electuary granule being packed of every bag.
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| CN201310232688.1A CN103349690B (en) | 2013-06-09 | 2013-06-09 | Comprehensive lactation-promotion medicine and preparation method thereof |
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| CN201310232688.1A CN103349690B (en) | 2013-06-09 | 2013-06-09 | Comprehensive lactation-promotion medicine and preparation method thereof |
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| CN103349690B CN103349690B (en) | 2015-01-07 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740174A (en) * | 2013-12-27 | 2015-07-01 | 常州渝继医药科技有限公司 | Drug for comprehensive conditioning of puerpera and preparation method thereof |
| CN108420860A (en) * | 2018-05-31 | 2018-08-21 | 刘玉华 | A kind of Chinese medicine composition of gynemetrics pregnant woman postpartum promoting lactation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695524A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Galactopoietic medicament and preparation method thereof |
| CN101695523A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Lactation qi and blood tonifying medicament and preparation method thereof |
| CN102579907A (en) * | 2012-03-18 | 2012-07-18 | 闫秋菊 | Lactation promoting soup |
-
2013
- 2013-06-09 CN CN201310232688.1A patent/CN103349690B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695524A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Galactopoietic medicament and preparation method thereof |
| CN101695523A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Lactation qi and blood tonifying medicament and preparation method thereof |
| CN102579907A (en) * | 2012-03-18 | 2012-07-18 | 闫秋菊 | Lactation promoting soup |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740174A (en) * | 2013-12-27 | 2015-07-01 | 常州渝继医药科技有限公司 | Drug for comprehensive conditioning of puerpera and preparation method thereof |
| CN108420860A (en) * | 2018-05-31 | 2018-08-21 | 刘玉华 | A kind of Chinese medicine composition of gynemetrics pregnant woman postpartum promoting lactation |
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| CN103349690B (en) | 2015-01-07 |
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