CN103349690B - Comprehensive lactation-promotion medicine and preparation method thereof - Google Patents
Comprehensive lactation-promotion medicine and preparation method thereof Download PDFInfo
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- CN103349690B CN103349690B CN201310232688.1A CN201310232688A CN103349690B CN 103349690 B CN103349690 B CN 103349690B CN 201310232688 A CN201310232688 A CN 201310232688A CN 103349690 B CN103349690 B CN 103349690B
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Abstract
The invention relates to a lactation-promotion medicine and a preparation method thereof. The medicine is prepared from Mongolian milkvetch root, red ginseng, banksian rose, common jujube, rice paper plant pith, cowherb seed, pangolin, Chinese thorowax root, white peony root, largehead atractylodes rhizome, ligusticum, and licorice root. The medicine is prepared according to a specific ratio. Through the steps of high-temperature leaching, filtering, heating and concentration, soft material preparation, granulation, drying, screening, packaging, and the like, instant granules are obtained. The medicine provides a comprehensive effect of qi nourishing, blood nourishing, liver soothing, and qi depression relieving. The medicine has a good lactation-promotion effect. With an average of 3 months of administration, milk secretion is adequate, and is enough for 12-18 months of feeding. The medicine is safe and reliable to human body.
Description
Technical field
The present invention relates to the medicinal preparation field of animals and plants material, particularly a kind of Lactogenic medicine and preparation method thereof.
Background technology
Research shows breast milk comprehensive nutrition, not only has the various materials needed for infants growth and development, and is easy to digest and assimilate, and in breast milk, also containing many immune factors, baby can improve immunity after absorbing.Breast milk is best Infants'feeding product, and in addition, breast milk also has special effect to the immunity of baby and psychology, and visible, breast milk plays vital effect to neonatal growth.
But, the symptom on some healths is often there is in puerpera in puerperal, for the puerpera that some bodies are thin, because postpartum hemorrhage is too much, cause puerpera's QI and blood deficiency, be embodied in degradation symptom under weak, pale complexion, hyperhidrosis, appetite, after this have impact on puerpera's production, the change of milk is raw, causes puerpera's milk little, does not even have.For the puerpera of QI and blood deficiency, need to adopt qi and blood tonifying method, promote that the change of puerpera's milk is raw.
In addition for the partially fat puerpera of some bodily forms, occur stagnation of QI due to depression of the liver symptom puerperal, lose blood puerperal less, have rosy cheeks, appetite extreme difference although be embodied in, with dyspepsia, depressed emotion, functional activity of QI being not smooth, this change that can affect milk is equally raw.For the puerpera of this class stagnation of QI due to depression of the liver, need to adopt dispersing the stagnated live-QI to relieve the stagnation of QI method, reach the effect of lactogenic.
For other puerperas, then there will be the summary symptom of QI and blood deficiency and stagnation of QI due to depression of the liver, the change having influence on puerpera's milk is raw.One of them reason is: puerperal QI and blood deficiency, cause puerpera's inappetence, depressed, melancholy for a long time, finally result in functional activity of QI being not smooth, stagnation of QI due to depression of the liver.At this time, solely adopt qi and blood tonifying method, or dispersing the stagnated live-QI to relieve the stagnation of QI method is nursed one's health to puerpera, does not have very good effect.
Summary of the invention
Technical problem to be solved by this invention is: puerpera produces rear appearance, the symptomes complice of QI and blood deficiency and stagnation of QI due to depression of the liver, the change having influence on puerpera's milk is raw, and solely adopts qi and blood tonifying method, or dispersing the stagnated live-QI to relieve the stagnation of QI method is nursed one's health puerpera, do not have very good effect.
For solving this technical problem: the technical solution used in the present invention is:
The invention provides a kind of Lactogenic medicine, this medicine contributes to, the symptomes complice of the QI and blood deficiency that conditioning puerpera causes puerperal and stagnation of QI due to depression of the liver, and play the effect that good promotion milkization is raw, the composition of this Lactogenic medicine, counts by weight
The Radix Astragali 38 ~ 42 parts, Radix Ginseng Rubra 19 ~ 21 parts, the Radix Aucklandiae 4.5 ~ 5.5 parts, 28.5 ~ 31.5 parts, Fructus Jujubae, Medulla Tetrapanacis 9.5 ~ 10.5 parts, Semen Vaccariae (stir-fry) 28.5 ~ 31.5 parts, Squama Manis (cannon) 14 ~ 16 parts, Radix Bupleuri 9.5 ~ 10.5 parts, the Radix Paeoniae Alba 19 ~ 21 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 19 ~ 21 parts, Radix Angelicae Sinensis 19 ~ 21 parts and 9.5 ~ 10.5 parts, Radix Glycyrrhizae
As preferably: the composition of Lactogenic medicine, count by weight: the Radix Astragali 40 parts, Radix Ginseng Rubra 20 parts, the Radix Aucklandiae 5 parts, 30 parts, Fructus Jujubae, Medulla Tetrapanacis 10 parts, Semen Vaccariae (stir-fry) 30 parts, Squama Manis (cannon) 15 parts, Radix Bupleuri 10 parts, the Radix Paeoniae Alba 20 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 20 parts, Radix Angelicae Sinensis 20 parts and 10 parts, Radix Glycyrrhizae
Above-described raw material, all needs the measured Chinese medicine of matter, can not use succedaneum.
This Lactogenic medicine is said solid preparation on pharmaceutics, specifically, is dissolved granule.
Present invention also offers a kind of preparation method of said medicine dissolved granule, specifically have the following steps
(1) preparation of raw material: take the raw material Radix Astragali, Radix Ginseng Rubra, the Radix Aucklandiae, Fructus Jujubae, Medulla Tetrapanacis, Semen Vaccariae (stir-fry), Squama Manis (cannon), Radix Bupleuri, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Angelicae Sinensis and Radix Glycyrrhizae by weight, put into extractor to be uniformly mixed, add the water soaking 30 minutes of 5-20 times amount;
(2) high-temp extracting and filtration: the raw material prepared in heating decoction step (1) 2-3 hours, leaching decocting liquid, its slag adds the water of 5-10 times amount again, heating decoction 1.5-2 hours, leaching decocting liquid, add the water of 4-6 times amount again toward its slag, heating decoction 1-1.5 hours, merges these three gained filtrates after filtering;
(3) heating is concentrated: by the filtrate of last for step (2) gained, heating is concentrated into paste, makes moisture be down to 28-31%;
(4) make soft material: by the thick paste of step (3) gained, add the starch of 2.5-3.5 times of volumes, stir, and then add the ethanol that volume ratio accounts for 70-90%, stir into uniform soft material;
(5) granulating is dry: soft material step (4) obtained, and makes granule through 12 mesh sieves, then by gained granule in 60-90 DEG C of Uniform Ventilation dryings;
(6) granule is screened: by the granule of step (5) gained; through 12 mesh sieve screenings; after suitably pulverizing without the granule of sieve; again again through 12 mesh sieve screenings; after being gathered by granule under twice screening, then sieve the fine powder gone wherein with 40 mesh sieves, obtain finished product electuary granule; not by the granule of 12 mesh sieves and the production that be can be used for next batch by the dust of 40 mesh sieves, be used for regulating the humidity of soft material.
(7) pack: by quantitative electuary granule being packed of often wrapping.
Be diagnosed as and suffer from the syndromic of QI and blood deficiency and stagnation of QI due to depression of the liver, hypogalactia type puerpera (in 24 hours puerperal, namely diagnosable go out result), can, within 24-36 hours puerperal, start to take lactagogue of the present invention, one day 3 times, a 10g 7 days is a course for the treatment of
When taking Lactogenic medicine electuary of the present invention, taboo and tobacco and wine, the mixed clothes of numb, peppery, raw, cold food;
When taking Lactogenic medicine electuary of the present invention, various Western medicine is taken in taboo;
During puerpera suffers from other diseases, forbid taking;
Take a period of time, after milk is unimpeded, needs timing by milk sucking-off, guarantee unblocked.
The invention has the beneficial effects as follows: lactagogue of the present invention is safe and reliable, instructions of taking is simple, and have the comprehensive function of qi and blood tonifying and dispersing the stagnated live-QI to relieve the stagnation of QI, the mechanism of action of medicine can promote that the second time hypertrophy of mammary glandular cell is grown, and produces good lactogenic effect.
Detailed description of the invention
Embodiment 1:
In the present embodiment, the composition of Lactogenic medicine, counts: the Radix Astragali 38 parts, Radix Ginseng Rubra 21 parts, the Radix Aucklandiae 4.5 parts, 28.5 parts, Fructus Jujubae, Medulla Tetrapanacis 10.5 parts, Semen Vaccariae (stir-fry) 31.5 parts, Squama Manis (cannon) 14 parts, Radix Bupleuri 10.5 parts, the Radix Paeoniae Alba 21 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 21 parts, Radix Angelicae Sinensis 19 parts and 10.5 parts, Radix Glycyrrhizae by weight.
The preparation method of dissolved granule as used in the description.
Embodiment 2:
In the present embodiment, the composition of Lactogenic medicine, counts: the Radix Astragali 40 parts, Radix Ginseng Rubra 20 parts, the Radix Aucklandiae 5 parts, 30 parts, Fructus Jujubae, Medulla Tetrapanacis 10 parts, Semen Vaccariae (stir-fry) 30 parts, Squama Manis (cannon) 15 parts, Radix Bupleuri 10 parts, the Radix Paeoniae Alba 20 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 20 parts, Radix Angelicae Sinensis 20 parts and 10 parts, Radix Glycyrrhizae by weight.
The preparation method of dissolved granule as used in the description.
Embodiment 3:
In the present embodiment, the composition of Lactogenic medicine, counts: the Radix Astragali 42 parts, Radix Ginseng Rubra 19 parts, the Radix Aucklandiae 5.5 parts, 31.5 parts, Fructus Jujubae, Medulla Tetrapanacis 9.5 parts, Semen Vaccariae (stir-fry) 28.5 parts, Squama Manis (cannon) 16 parts, Radix Bupleuri 9.5 parts, the Radix Paeoniae Alba 19 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 19 parts, Radix Angelicae Sinensis 21 parts and 9.5 parts, Radix Glycyrrhizae by weight.
The preparation method of dissolved granule as used in the description.
In order to verify the actual effect of medicine of the present invention, the hypogalactia puerpera 240 routine inventors being participated in person to clinical treatment has done clinical trial, and these 240 puerperas are diagnosed as the symptomes complice suffering from QI and blood deficiency and stagnation of QI due to depression of the liver puerperal.
240 puerperas are divided into 4 groups at random, are respectively A group, B group, C group, D group, often organize 60 people,
A, B, C these 3 groups, 36 hours puerperal, takes the Lactogenic medicine dissolved granule of embodiment 1, embodiment 2 and embodiment 3 respectively, one day 3 times, a 10g, within 7 days, is a course for the treatment of; D group as a control group, accepts routine obstetric Primary Care.
Therapeutic effect formulates clinical observation according to " traditional Chinese medical science medical diagnosis on disease criterion of therapeutical effect " and " new drug (Chinese medicine) guideline of clinical investigations ":
(1) clinical criteria: puerperal hypogalactia is women's postpartum breastfeeding phase, galactopoiesis amount few or completely without, the needs of feeding infant can not be met.
(2) tcm syndrome standard:
QI and blood deficiency: puerperal, breast was few, very less or completely without, milk is rare clearly, without swollen sense.Companion's lustreless complexion, mental fatigue with loss of appetite.Light red tongue, few tongue, deficient and thready pulse.
Stagnation of QI due to depression of the liver: puerperal, breast was few, very less or completely without, distending pain of the breast or slight fever.The breast side of body is unhappy.Irritated at heart, diet reduces, tongue fur BOHUANG, stringy pulse.
(3) curative effect judging standard:
Effective: galactopoiesis increases, but inadequate feeding infant;
Effective: galactopoiesis is more, but still inadequate feeding infant;
Good effect: galactopoiesis is a lot, normally can feed baby;
Invalid: galactopoiesis is without change.
Take the puerpera of drug particles electuary of the present invention, after having taken a course for the treatment of, the transference cure of deficient qi and blood and stagnation of QI due to depression of the liver, tongue fur and pulse condition have recovered normal, and complexion is improved, and appetite increases, and milk increases, and mammary gland Rana guadranus increases gradually.
Estimating curative effect is carried out by the galactopoiesis amount after taking a course for the treatment of, concrete as described in table 1-4:
Show the curative effect statistics after the lactagogue dissolved granule of 60 routine maternity clothing embodiments 1 in 1A group
Show the curative effect statistics after the lactagogue dissolved granule of 60 routine maternity clothing embodiments 2 in 2B group
Show the curative effect statistics after the lactagogue dissolved granule of 60 routine maternity clothing embodiments 3 in 3C group
Curative effect after 60 routine puerperas accept routine obstetric Primary Care in table 4D group is added up
For 180 puerperas taking lactagogue of the present invention, effect occurs after taking 1-3 days, within 4-6 days, reaches remarkable result taking, puerpera's QI and blood is sufficient, and milk obviously increases, and breast fills, produce swelling sense, after 7 days, the transference cure of QI and blood deficiency and stagnation of QI due to depression of the liver.
For 180 puerperas taking lactagogue of the present invention, after taking 3 courses for the treatment of, galactopoiesis is sufficient, enough baby clothes breast milks more than 1 year.Take above-mentioned 180 puerperas of lactagogue of the present invention, not yet find the generation of a routine breast cancer case, this medicine is safe and reliable as seen.
Claims (5)
1. a comprehensive lactation-promotion medicine, is characterized in that: the composition of described Lactogenic medicine, counts by weight
The Radix Astragali 38 ~ 42 parts, Radix Ginseng Rubra 19 ~ 21 parts, the Radix Aucklandiae 4.5 ~ 5.5 parts, 28.5 ~ 31.5 parts, Fructus Jujubae, Medulla Tetrapanacis 9.5 ~ 10.5 parts, Semen Vaccariae (stir-fry) 28.5 ~ 31.5 parts, Squama Manis (cannon) 14 ~ 16 parts, Radix Bupleuri 9.5 ~ 10.5 parts, the Radix Paeoniae Alba 19 ~ 21 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 19 ~ 21 parts, Radix Angelicae Sinensis 19 ~ 21 parts and 9.5 ~ 10.5 parts, Radix Glycyrrhizae.
2. Lactogenic medicine as claimed in claim 1, is characterized in that: the composition of described Lactogenic medicine, counts by weight
The Radix Astragali 40 parts, Radix Ginseng Rubra 20 parts, the Radix Aucklandiae 5 parts, 30 parts, Fructus Jujubae, Medulla Tetrapanacis 10 parts, Semen Vaccariae (stir-fry) 30 parts, Squama Manis (cannon) 15 parts, Radix Bupleuri 10 parts, the Radix Paeoniae Alba 20 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 20 parts, Radix Angelicae Sinensis 20 parts and 10 parts, Radix Glycyrrhizae.
3. Lactogenic medicine as claimed in claim 1, is characterized in that: described Lactogenic medicine is said solid preparation on pharmaceutics.
4. Lactogenic medicine as claimed in claim 3, is characterized in that: described Lactogenic medicine is dissolved granule.
5. the preparation method of the Lactogenic medicine as described in any one of Claims 1-4, is characterized in that: said method comprising the steps of:
(1) preparation of raw material: take the raw material Radix Astragali, Radix Ginseng Rubra, the Radix Aucklandiae, Fructus Jujubae, Medulla Tetrapanacis, Semen Vaccariae (stir-fry), Squama Manis (cannon), Radix Bupleuri, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Angelicae Sinensis and Radix Glycyrrhizae by weight, put into extractor to be uniformly mixed, add the water soaking 30 minutes of 5-20 times amount;
(2) high-temp extracting and filtration: the raw material prepared in heating decoction step (1) 2-3 hours, leaching decocting liquid, its slag adds the water of 5-10 times amount again, heating decoction 1.5-2 hours, leaching decocting liquid, add the water of 4-6 times amount again toward its slag, heating decoction 1-1.5 hours, merges these three gained filtrates after filtering;
(3) heating is concentrated: by the filtrate of last for step (2) gained, heating is concentrated into paste, makes moisture be down to 28-31%;
(4) make soft material: by the thick paste of step (3) gained, add the starch of 2.5-3.5 times of volumes, stir, and then add the ethanol that volume ratio accounts for 70-90%, stir into uniform soft material;
(5) granulating is dry: soft material step (4) obtained, and makes granule through 12 mesh sieves, then by gained granule in 60-90 DEG C of Uniform Ventilation dryings;
(6) granule is screened: by the granule of step (5) gained; through 12 mesh sieve screenings; after suitably pulverizing without the granule of sieve; again again through 12 mesh sieve screenings; after being gathered by granule under twice screening, then sieve the fine powder gone wherein with 40 mesh sieves, obtain finished product electuary granule; not by the granule of 12 mesh sieves and the production that be can be used for next batch by the dust of 40 mesh sieves, be used for regulating the humidity of soft material.
(7) pack: by quantitative electuary granule being packed of often wrapping.
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| CN104740174A (en) * | 2013-12-27 | 2015-07-01 | 常州渝继医药科技有限公司 | Drug for comprehensive conditioning of puerpera and preparation method thereof |
| CN108420860A (en) * | 2018-05-31 | 2018-08-21 | 刘玉华 | A kind of Chinese medicine composition of gynemetrics pregnant woman postpartum promoting lactation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695524A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Galactopoietic medicament and preparation method thereof |
| CN101695523A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Lactation qi and blood tonifying medicament and preparation method thereof |
| CN102579907A (en) * | 2012-03-18 | 2012-07-18 | 闫秋菊 | Lactation promoting soup |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695524A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Galactopoietic medicament and preparation method thereof |
| CN101695523A (en) * | 2009-10-23 | 2010-04-21 | 王继 | Lactation qi and blood tonifying medicament and preparation method thereof |
| CN102579907A (en) * | 2012-03-18 | 2012-07-18 | 闫秋菊 | Lactation promoting soup |
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