Summary of the invention
The invention provides a kind of medicine and the preparation method that are used for the treatment of dysmenorrhea, medicine of the present invention has depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, enriches blood and adjust effect of blood, menstruction regulating and pain relieving, be applicable to treatment because of all types of dysmenorrheas caused by qi depression to blood stasis, congealing cold with blood stasis, preparation technology is simple, cheap, good effect, instant effect, have no side effect, can all symptoms of relieving dysmenorrhea rapidly, reach the therapeutic effect of warm palace pain relieving.
For achieving the above object, being implemented as follows of technical scheme of the present invention:
Be used for the treatment of a medicine for dysmenorrhea, raw material composition and the parts by weight of making described effective ingredient are:
Radix Berchemiae Giraldianae 50 ~ 83 parts of Herba Iresines Herbstiis 49 ~ 80 portions of jasmines 49 ~ 75 portions of Herba Bidentis Bipinnatae 45 ~ 70 parts
Chicken feet 7 40 ~ 69 parts of salvia bowleyana Dunns 35 ~ 65 parts of Ovisammon Linnaeus. 32 ~ 60 portions of Rhizoma Rodgersiae 30 ~ 58 parts
Radix Ribis Viridiflori 28 ~ 55 parts of Wasabia japonic (Euterma Wasabi)s 25 ~ 54 parts of Serpentis pimples 24 ~ 50 parts of Flos jasmini 20 ~ 47 parts
Rhizoma Cyperi 19 ~ 45 parts of Radix Tylophorae Yunnanensis 15 ~ 40 parts of moccasin trees 12 ~ 34 parts of Folium Rhododendri Micranthi 10 ~ 30 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Berchemiae Giraldianae 55 ~ 80 parts of Herba Iresines Herbstiis 53 ~ 75 portions of jasmines 52 ~ 70 portions of Herba Bidentis Bipinnatae 48 ~ 67 parts
Chicken feet 7 45 ~ 65 parts of salvia bowleyana Dunns 38 ~ 60 parts of Ovisammon Linnaeus. 35 ~ 57 portions of Rhizoma Rodgersiae 33 ~ 55 parts
Radix Ribis Viridiflori 31 ~ 51 parts of Wasabia japonic (Euterma Wasabi)s 28 ~ 50 parts of Serpentis pimples 27 ~ 45 parts of Flos jasmini 25 ~ 43 parts
Rhizoma Cyperi 22 ~ 40 parts of Radix Tylophorae Yunnanensis 18 ~ 37 parts of moccasin trees 15 ~ 31 parts of Folium Rhododendri Micranthi 13 ~ 25 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Berchemiae Giraldianae 60 ~ 75 parts of Herba Iresines Herbstiis 56 ~ 70 portions of jasmines 55 ~ 67 portions of Herba Bidentis Bipinnatae 51 ~ 64 parts
Chicken feet 7 50 ~ 62 parts of salvia bowleyana Dunns 45 ~ 57 parts of Ovisammon Linnaeus. 40 ~ 54 portions of Rhizoma Rodgersiae 36 ~ 52 parts
Radix Ribis Viridiflori 34 ~ 50 parts of Wasabia japonic (Euterma Wasabi)s 31 ~ 45 parts of Serpentis pimples 30 ~ 42 parts of Flos jasmini 28 ~ 40 parts
Rhizoma Cyperi 25 ~ 37 parts of Radix Tylophorae Yunnanensis 21 ~ 35 parts of moccasin trees 18 ~ 28 parts of Folium Rhododendri Micranthi 16 ~ 20 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Berchemiae Giraldianae 68 parts of Herba Iresines Herbstiis 63 portions of jasmines 61 portions of Herba Bidentis Bipinnatae 57 parts
Chicken feet 7 56 parts of salvia bowleyana Dunns 51 parts of Ovisammon Linnaeus. 47 portions of Rhizoma Rodgersiae 44 parts
Radix Ribis Viridiflori 42 parts of Wasabia japonic (Euterma Wasabi)s 38 parts of Serpentis pimples 36 parts of Flos jasmini 34 parts
Rhizoma Cyperi 31 parts of Radix Tylophorae Yunnanensis 28 parts of moccasins set 23 parts of Folium Rhododendri Micranthi 18 parts.
Be used for the treatment of a preparation method for the medicine of dysmenorrhea, comprise following processing step:
(1) Radix Berchemiae Giraldianae and Herba Iresines Herbstii are cleaned, chopping, strand juice, filter impurity, stays juice for subsequent use;
(2) get jasmine, Herba Bidentis Bipinnatae, chicken feet seven, salvia bowleyana Dunn, Ovisammon Linnaeus., Rhizoma Cyperi, Radix Ribis Viridiflori, Wasabia japonic (Euterma Wasabi), Flos jasmini and Folium Rhododendri Micranthi to clean, put into container, add the distilled water of 6-8 times amount, soak after 2-3 hour, boil 3-4 hour, extract; Again add 3-5 times amount distilled water, boil 2-3 hour, extract; Finally, add 2-3 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(3) get Rhizoma Rodgersiae to clean, section, dries, puts into mortar, grind into powder, crosses 120 order fine powders, for subsequent use;
(4) get moccasin tree and Radix Tylophorae Yunnanensis clean, immerse the alcohol solution dipping 2-3 hour of 65% of 5 times amount, heated and boiled 1-2 hour, extract, filtration, obtain filtrate for subsequent use;
(5) Serpentis pimple is pulverized, grind into powder, cross 200 order fine powders, for subsequent use;
(6) by juice made for above-mentioned steps (1)-(5), filtrate and fine powder mixing, make capsule through modern science technique, obtain medicine of the present invention.
The property of medicine of the present invention's medicine used is as follows:
Radix Berchemiae Giraldianae: sweet in the mouth, micro-puckery, slightly warm in nature.Spleen reinforcing dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral, menstruction regulating and pain relieving.Wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral, relieving cough and resolving phlegm, invigorating the spleen and benefiting QI.Dispelling the wind and dampness pathogens arthralgia, lumbago, dysmenorrhea, pulmonary tuberculosis, scrofula, infantile malnutrition, hepatitis, biliary tract ascarid, venom, traumatic injury.
Herba Iresines Herbstii: sweet in the mouth, micro-hardship, cool in nature.Return liver, large intestine channel.Cooling blood for hemostasis, clearing away heat-damp and promoting diuresis, removing toxic substances.Cure mainly haematemesis, epistaxis, hemoptysis, have blood in stool, metrorrhagia, dysentery, have loose bowels, damp-heat vaginal discharge, carbuncle." mountain of papers Chinese herbal medicine " carries: " relaxing muscles and tendons to promote blood circulation, menstruction regulating and pain relieving.Control menoxenia, epistaxis, dysmenorrhea, fracture.”
Jasmine: acrid in the mouth, sweet, property is put down.Modern medicine study confirms, jasmine has dispersing the stagnated live-QI to relieve the stagnation of QI, invigorating the spleen and regulating the stomach, effect of regulating QI to relieve pain.Be applicable to the pain in chest and hypochondrium that depression of liver-QI causes, lose arthralgia pain between the side of body after chronic hepatitis, the diseases such as dysmenorrhes.
Herba Bidentis Bipinnatae: sweet in the mouth, micro-pungent, flat.Antiinflammatory, sterilization, menstruction regulating and pain relieving.Cure mainly uterine prolapse, proctoptosis, stomachache, amenorrhea, psoriasis, neurodermatitis.Modern medicine study confirms, Herba Bidentis Bipinnatae has the effect of antiinflammatory, sterilization, menstruction regulating and pain relieving.
Chicken feet seven: bitter in the mouth is flat.Expelling wind and activating blood circulation, strengthening the spleen and stomach, menstruction regulating and pain relieving.For lumbago, skelalgia of rheumatism, traumatic injury, dyspepsia, menoxenia, leucorrhea.
Salvia bowleyana Dunn: bitter in the mouth, cold nature.Blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving.Cure mainly thoracic obstruction angor, vexed, cardiopalmus, epigastric pain, menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, metrorrhagia, tripe splenomegaly, arthralgia, colicky, skin ulcer swells.
Ovisammon Linnaeus.: bitter in the mouth, warm in nature.Return lung, liver, kidney three warp.Menstruction regulating and pain relieving.Cure mainly dysmenorrhea, leucorrhoea grow in quantity." Medical Animals In China will " carries: " have effect of menstruction regulating and pain relieving.Cure mainly the lower abdominal pain that menoxenia causes.”
Rhizoma Rodgersiae: bitter in the mouth, puckery, cool in nature.Clearing away heat and cooling blood, menstruction regulating and pain relieving.For enteritis, dysentery, dysmenorrhea, menorrhagia, rheumatic arthritis, traumatic injury, traumatic hemorrhage is controlled in external, eczema scrotum." choosing of Yunnan Chinese herbal medicine " carries: " antiinflammatory, convergence, alunite of dispeling the wind, pain relieving.Control knife injury hemorrhage, traumatic injury, rheumatic arthritis, dysentery, diarrhoea.”
Radix Ribis Viridiflori: sweet in the mouth, hardship, flat.Enter the heart, spleen two warp.Heat clearing and blood cooling, regulating menstruation.Main deficiency-heat is weak, menoxenia, dysmenorrhea." will planted by Tianmu Mountains of Zhejiang Province medicine " carries: " control women's dysphoria with feverish sensation in the chest palms and soles, limbs fatigue, or menoxenia, menalgia.”
Wasabia japonic (Euterma Wasabi): bitter in the mouth is pungent, property is put down.Menstruction regulating and pain relieving, dispelling wind to relieve the exterior syndrome.Control menoxenia, dysmenorrhea, flu, cardiac and abdominal pain.Blood stasis dispelling, separates sore.Control skin mange, sore, pulmonary tuberculosis cough, fracture bruise." choosing of Simao, Yunnan Chinese herbal medicine " carries: " menstruction regulating and pain relieving, dispelling wind to relieve the exterior syndrome.Control menoxenia, dysmenorrhea, flu, cardiac and abdominal pain.”
Serpentis pimple: bitter in the mouth, micro-sweet, puckery, property is put down.Anti-inflammtory anti-dysentery, menstruction regulating and pain relieving, hemostasis.For enteritis, bacillary dysentery, menoxenia, dysmenorrhea, rheumatalgia, fracture, traumatic injury swelling and pain due to blood stasis.
Flos jasmini: mildly bitter flavor, property is put down.Return Liver Channel.Soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain.The side of body rib gastral cavity abdomen cured mainly caused by stagnation of QI due to depression of the liver is had a pain, and dysentery is suffered from abdominal pain.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " treating the liver hepatic region that is scorching, liver cirrhosis is sick, and costa sternales does not relax, heart peratodynia, and dysentery is suffered from abdominal pain.”
Rhizoma Cyperi: acrid in the mouth, micro-hardship, micro-sweet, property is put down.Return liver, spleen, tri-jiao channel.To regulate the flow of vital energy resolving depression, pain relieving regulating menstruation.Treating the liver discomfort in the stomach, depression of QI, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea." detailed outline " carries: " loose seasonal epidemic pathogens is trembled with fear epidemic disease, and profit three is burnt, and separate six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot; abdominal distention, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, and ulcer sores is spitted blood; hematochezia, hematuria, married woman's bleeding not during menses, and the moon waits uncomfortable, before tire puerperal all kinds of diseases and ailments.”
Radix Tylophorae Yunnanensis: bitter in the mouth, pungent, slightly warm in nature.Return liver, spleen channel.Kuai, a state in the Zhou Dynasty dish dredging collateral, promoting blood circulation and stopping pain.Cure mainly rheumatic ostalgia, hepatitis, gastric ulcer, poliomyelitis sequela, traumatic injury." Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons to promote blood circulation, menstruction regulating and pain relieving.Control traumatic injury, rheumatic ostalgia, hepatitis, gastric ulcer, chronic consumptive disease, pernicious malaria.”
Moccasin is set: sweet in the mouth, pungent, and slightly warm in nature is slightly poisonous.Expelling wind and removing dampness, menstruction regulating and pain relieving.Cure mainly rheumatic numbness, bones and muscles pain, traumatic injury, epilepsy, menoxenia, dysmenorrhea, trick in menstrual period cold type of pain." China's book on Chinese herbal medicine " carries: " wind-expelling pain-stopping, promoting blood flow to regulate menstruation.Main air pain of dampness syndrome, traumatic injury, menoxenia, dysmenorrhea, furuncle furuncle and phyma.”
Folium Rhododendri Micranthi: sour in the mouth, pungent, warm in nature.Very toxic.Dispelling wind and removing obstruction in the collateral, menstruction regulating and pain relieving, preventing phlegm from forming and stopping coughing.For chronic tracheitis, rheumatic arthralgia, lumbago, dysmenorrhea, puerperal arthralgia." plateau Chinese herbal treatment handbook " carries: " control bronchitis, dysentery, analgesia, external application is fractured.”
The present invention compared with prior art, has following beneficial effect:
Medicine of the present invention has depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, enriches blood and adjust effect of blood, menstruction regulating and pain relieving, be applicable to treatment because of all types of dysmenorrheas caused by qi depression to blood stasis, congealing cold with blood stasis, preparation technology is simple, cheap, good effect, instant effect, has no side effect, can all symptoms of relieving dysmenorrhea rapidly, reach the therapeutic effect of warm palace pain relieving.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Radix Berchemiae Giraldianae 80g Herba Iresines Herbstii 75g jasmine 70g Herba Bidentis Bipinnatae 67g
Chicken feet seven 65g salvia bowleyana Dunn 60g Ovisammon Linnaeus. 57g Rhizoma Rodgersiae 55g
Radix Ribis Viridiflori 51g Wasabia japonic (Euterma Wasabi) 50g Serpentis pimple 45g Flos jasmini 43g
Rhizoma Cyperi 40g Radix Tylophorae Yunnanensis 37g moccasin tree 31g Folium Rhododendri Micranthi 25g.
Be used for the treatment of a preparation method for the medicine of dysmenorrhea, comprise following processing step:
(1) Radix Berchemiae Giraldianae and Herba Iresines Herbstii are cleaned, chopping, strand juice, filter impurity, stays juice for subsequent use;
(2) get jasmine, Herba Bidentis Bipinnatae, chicken feet seven, salvia bowleyana Dunn, Ovisammon Linnaeus., Rhizoma Cyperi, Radix Ribis Viridiflori, Wasabia japonic (Euterma Wasabi), Flos jasmini and Folium Rhododendri Micranthi to clean, put into container, add the distilled water of 6-8 times amount, soak after 2-3 hour, boil 3-4 hour, extract; Again add 3-5 times amount distilled water, boil 2-3 hour, extract; Finally, add 2-3 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(3) get Rhizoma Rodgersiae to clean, section, dries, puts into mortar, grind into powder, crosses 120 order fine powders, for subsequent use;
(4) get moccasin tree and Radix Tylophorae Yunnanensis clean, immerse the alcohol solution dipping 2-3 hour of 65% of 5 times amount, heated and boiled 1-2 hour, extract, filtration, obtain filtrate for subsequent use;
(5) Serpentis pimple is pulverized, grind into powder, cross 200 order fine powders, for subsequent use;
(6) by juice made for above-mentioned steps (1)-(5), filtrate and fine powder mixing, make capsule through modern science technique, obtain medicine of the present invention.
Usage and dosage: oral, menstrual period or through first three sky, a 2-3 grain, 3 times on the one; Through after can continue to take, a 2-3 grain, 2-3 time on the one, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Radix Berchemiae Giraldianae 75g Herba Iresines Herbstii 70g jasmine 67g Herba Bidentis Bipinnatae 64g
Chicken feet seven 62g salvia bowleyana Dunn 57g Ovisammon Linnaeus. 54g Rhizoma Rodgersiae 52g
Radix Ribis Viridiflori 50g Wasabia japonic (Euterma Wasabi) 45g Serpentis pimple 42g Flos jasmini 40g
Rhizoma Cyperi 37g Radix Tylophorae Yunnanensis 35g moccasin tree 28g Folium Rhododendri Micranthi 20g.
The present embodiment process for preparing medicine processing step and using method identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Radix Berchemiae Giraldianae 68g Herba Iresines Herbstii 63g jasmine 61g Herba Bidentis Bipinnatae 57g
Chicken feet seven 56g salvia bowleyana Dunn 51g Ovisammon Linnaeus. 47g Rhizoma Rodgersiae 44g
Radix Ribis Viridiflori 42g Wasabia japonic (Euterma Wasabi) 38g Serpentis pimple 36g Flos jasmini 34g
Rhizoma Cyperi 31g Radix Tylophorae Yunnanensis 28g moccasin tree 23g Folium Rhododendri Micranthi 18g.
The present embodiment process for preparing medicine processing step and using method identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Radix Berchemiae Giraldianae 60g Herba Iresines Herbstii 58g jasmine 57g Herba Bidentis Bipinnatae 52g
Chicken feet seven 50g salvia bowleyana Dunn 45g Ovisammon Linnaeus. 40g Rhizoma Rodgersiae 38g
Radix Ribis Viridiflori 37g Wasabia japonic (Euterma Wasabi) 33g Serpentis pimple 32g Flos jasmini 29g
Rhizoma Cyperi 27g Radix Tylophorae Yunnanensis 23g moccasin tree 19g Folium Rhododendri Micranthi 16g.
The present embodiment process for preparing medicine processing step and using method identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Radix Berchemiae Giraldianae 55g Herba Iresines Herbstii 53g jasmine 52g Herba Bidentis Bipinnatae 48g
Chicken feet seven 45g salvia bowleyana Dunn 38g Ovisammon Linnaeus. 35g Rhizoma Rodgersiae 33g
Radix Ribis Viridiflori 31g Wasabia japonic (Euterma Wasabi) 28g Serpentis pimple 27g Flos jasmini 25g
Rhizoma Cyperi 22g Radix Tylophorae Yunnanensis 18g moccasin tree 15g Folium Rhododendri Micranthi 13g.
The present embodiment process for preparing medicine processing step and using method identical with embodiment 1.
Clinical data:
1, case selection:
Select the routine clinical observation of I institute Out-patient Clinic of Department of Gynecology dysmenorrhea patient 400.Patient is divided into treatment group and matched group at random, treatment group 200 example, 13 ~ 32 years old age, 21.3 years old mean age, average 4.5 years of the course of disease; Matched group 200 example, 14 ~ 31 years old age, 20.9 years old mean age, average 4.7 years of the course of disease.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, menstrual period or through first three sky, a 2-3 grain, 3 times on the one; Through after can continue to take, a 2-3 grain, 2-3 time on the one, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes Tongjinglin Granules, and boiled water is taken after mixing it with water, and menstrual onset starts to take medicine with the first five sky, the next day clothes, each serving with 1 ~ 2 bag, 2 times on the one; Serve on two after starting menstrual period, two to three menstrual period are a course for the treatment of; Severe patient is usually invalid.
3, efficacy determination:
(1) effective: pain symptom obviously disappears, body constitution recovers normal, observes 1 year without recurrence;
(2) effective: pain symptom makes moderate progress, and body constitution is progressively recovered;
(3) invalid: pain symptom, without change, does not reach analgesic effect.
4, therapeutic outcome (seeing the following form):
Show result as can be seen from the table, the total effective rate for the treatment of group is apparently higher than the effective percentage of matched group.