CN103340956A - External compound preparation for treating burns and scalds and promoting wound healing and preparation method of preparation - Google Patents

External compound preparation for treating burns and scalds and promoting wound healing and preparation method of preparation Download PDF

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Publication number
CN103340956A
CN103340956A CN2013103044187A CN201310304418A CN103340956A CN 103340956 A CN103340956 A CN 103340956A CN 2013103044187 A CN2013103044187 A CN 2013103044187A CN 201310304418 A CN201310304418 A CN 201310304418A CN 103340956 A CN103340956 A CN 103340956A
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preparation
wound healing
external
compound preparation
water extract
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CN2013103044187A
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Chinese (zh)
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杨如会
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Lishui University
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Lishui University
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Priority to CN2013103044187A priority Critical patent/CN103340956A/en
Publication of CN103340956A publication Critical patent/CN103340956A/en
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Abstract

The invention discloses an external-use compound preparation for treating burns and scalds and promoting wound healing. The external compound preparation comprises the following components in percentage by weight: 30%-80% of sesame oil, 6%-40% of antigalactic mouse, 5%-30% of concentrated water extract of jasmine and 1%-20% of borneol. The invention further discloses a preparation method of the external-use compound preparation for treating burns and scalds and promoting wound healing. The preparation method comprises the following steps of: a, preparing the antigalactic mouse; b, preparing the concentrated water extract of jasmine; c, preparing the bornel; and d, mixing the antigalactic mouse, the concentrated water extract of jasmine, the bornel and the sesame oil in the proportion to obtain the external compound preparation for treating burns and scalds and promoting wound healing. The external compound preparation has a better treatment effect on I-level or II-level burns and scalds, and skin mucosa injury.

Description

Compound preparation and the preparation method of external-used burn and scald treating and promotion wound healing
Technical field
The present invention relates to a kind of a variety of causes external-used burn and scald treating that causes and compound preparation that promotes wound healing for the treatment of, also relate to the preparation method of the compound preparation of a kind of external-used burn and scald treating and promotion wound healing.
Background technology
Burn and scald is common unexpected injury in the life, and boiling water, the burn and scald that rolls medicated porridge, deep fat, heat steam are the things that regular meeting takes place.To some burn and scald, if handle in time, just can not cause bad consequence.The treatment of burn and scald mainly is pain relieving, protect from infection, promote the healing of skin histology, if untimely treatment or deal with improperly, can cause the contracture of serious cicatrization and skin histology after the healing, to the life of patient's prognosis with attractive in appearancely cause irremediable injury.
Skin injury, particularly scratch, lacerated wound, incision etc. are common skin or mucosa injuries in the daily life, as deal with improperly, can cause wound infection, cicatrization, pigmentation etc., to patient's organ dysfunction and attractive in appearance making a big impact.
Summary of the invention
The objective of the invention is to solve the skin burn that prior art exists and deal with the technical problem that can cause wound to be difficult to heal improperly.
The invention provides the compound preparation of a kind of external-used burn and scald treating and promotion wound healing, it is characterized in that: comprise that mass percent is: 30%-80% Oleum Sesami, 6%-40% neonatal rat processed, the concentrated water extract of 5-30% Fructus Gardeniae and 1-20% Borneolum Syntheticum.
The present invention also provides a kind of external-used burn and scald treating and promotes the preparation method of the compound preparation of wound healing, it is characterized in that, comprises the steps:
A will newly be born and put to death after the blood-letting of 1-3 days SPF level sterilized rats, and the sterile cryogenic pulverizer is pulverized, and put into Oleum Sesami and soak 20-45 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 20-40 minute, collected the supernatant decoction liquor, filtered the back and concentrated with Rotary Evaporators, obtained the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami are mixed in proportion the compound preparation that obtains external-used burn and scald treating and promote wound healing.
The present invention has curative effect preferably to I degree or II degree burn and scald, mucocutaneous injury.
The specific embodiment
The invention provides the compound preparation of a kind of external-used burn and scald treating and promotion wound healing, comprise that mass percent is: 30%-80% Oleum Sesami, 6%-40% neonatal rat processed, the concentrated water extract of 5-30% Fructus Gardeniae and 1-20% Borneolum Syntheticum.
The present invention also provides a kind of external-used burn and scald treating and promotes the preparation method of the compound preparation of wound healing, comprises the steps:
A will newly be born and put to death after the blood-letting of 1-3 days SPF level sterilized rats, and the sterile cryogenic pulverizer is pulverized, and put into Oleum Sesami and soak 20-45 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 20-40 minute, collected the supernatant decoction liquor, filtered the back and concentrated with Rotary Evaporators, obtained the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami are mixed in proportion the compound preparation that obtains external-used burn and scald treating and promote wound healing.
Operating position of the present invention: I degree or II degree burn and scald, the person does not puncture blister the blister, and get compound preparation of the present invention and be applied to wound surface, thickness such as thin paper, one is for several times, becomes dry as medicine, removes behind the outmoded medicine coating again, does not advise wrapping.
Mucocutaneous injury is got compound preparation of the present invention and is applied to wound, and one is for several times, excessive as wound surface, cross deeply in time debridement and suturing after, effectively behind the infection for this medicine.
Embodiment 1
The preparation method of the compound preparation of a kind of external-used burn and scald treating and promotion wound healing comprises the steps:
A will newly be born and put to death after the blood-letting of 2 days SPF level sterilized rats, and the sterile cryogenic pulverizer is pulverized, and put into Oleum Sesami and soak 30 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 30 minutes, collected the supernatant decoction liquor, filtered the back and concentrated with Rotary Evaporators, obtained the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami by mass percentage the 6%:10%:10%:74% ratio mix the compound preparation that obtains external-used burn and scald treating and promote wound healing.
Embodiment 2
The preparation method of the compound preparation of a kind of external-used burn and scald treating and promotion wound healing comprises the steps:
A will newly be born and put to death after the blood-letting of 1 day SPF level sterilized rat, and the sterile cryogenic pulverizer is pulverized, and put into Oleum Sesami and soak 20 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 20 minutes, collected the supernatant decoction liquor, filtered the back and concentrated with Rotary Evaporators, obtained the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami by mass percentage the 20%:5%:20%:55% ratio mix the compound preparation that obtains external-used burn and scald treating and promote wound healing.
Embodiment 3
The preparation method of the compound preparation of a kind of external-used burn and scald treating and promotion wound healing comprises the steps:
A will newly be born and put to death after the blood-letting of 3 days SPF level sterilized rats, and the sterile cryogenic pulverizer is pulverized, and put into Oleum Sesami and soak 45 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 40 minutes, collected the supernatant decoction liquor, filtered the back and concentrated with Rotary Evaporators, obtained the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami by mass percentage the 40%:29%:1%:30% ratio mix the compound preparation that obtains external-used burn and scald treating and promote wound healing.
Although this paper has used terms such as neonatal rat processed, Fructus Gardeniae, Borneolum Syntheticum, burn and scald, mucocutaneous injury morely, do not get rid of the probability of using other term.Using these terms only is in order to describe and explain essence of the present invention more easily; They are construed to any additional restriction all is contrary with spirit of the present invention.

Claims (6)

1. the compound preparation of external-used burn and scald treating and promotion wound healing is characterized in that: comprise that mass percent is: 30%-80% Oleum Sesami, 6%-40% neonatal rat processed, the concentrated water extract of 5%-30% Fructus Gardeniae and 1%-20% Borneolum Syntheticum.
2. the compound preparation of external-used burn and scald treating according to claim 1 and promotion wound healing is characterized in that: comprise that mass percent is: 74% Oleum Sesami, 6% neonatal rat processed, the concentrated water extract of 10% Fructus Gardeniae and 10% Borneolum Syntheticum.
3. the preparation method of the compound preparation of external-used burn and scald treating and promotion wound healing is characterized in that, comprises the steps:
A will newly be born and put to death after the blood-letting of 1-3 days SPF level sterilized rats, and pulverizer is pulverized, and put into Oleum Sesami and soak 20-45 days, obtain neonatal rat processed;
B Chinese medicine Fructus Gardeniae decocted 20-40 minute, collected the supernatant decoction liquor, filtered the back and concentrated the concentrated water extract of Fructus Gardeniae;
C grinds the Chinese medicine Borneolum Syntheticum back and places;
D will neonatal rat processed, the concentrated water extract of Fructus Gardeniae, Borneolum Syntheticum, Oleum Sesami are mixed in proportion the compound preparation that obtains external-used burn and scald treating and promote wound healing.
4. the preparation method of the compound preparation of external-used burn and scald treating according to claim 3 and promotion wound healing is characterized in that pulverizer is the sterile cryogenic pulverizer among the described step a.
5. the preparation method of the compound preparation of external-used burn and scald treating according to claim 3 and promotion wound healing is characterized in that, concentrates among the described step b and adopts Rotary Evaporators to concentrate.
6. external-used burn and scald treating according to claim 3 and promote the preparation method of the compound preparation of wound healing, it is characterized in that the concentrated water extract of neonatal rat processed, Fructus Gardeniae, Borneolum Syntheticum, the Oleum Sesami ratio mixing of 6%-40%:5%-30%:1%-20%:30%-80% by mass percentage in the steps d.
CN2013103044187A 2013-07-17 2013-07-17 External compound preparation for treating burns and scalds and promoting wound healing and preparation method of preparation Pending CN103340956A (en)

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CN2013103044187A CN103340956A (en) 2013-07-17 2013-07-17 External compound preparation for treating burns and scalds and promoting wound healing and preparation method of preparation

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Application Number Priority Date Filing Date Title
CN2013103044187A CN103340956A (en) 2013-07-17 2013-07-17 External compound preparation for treating burns and scalds and promoting wound healing and preparation method of preparation

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902669A (en) * 2016-04-29 2016-08-31 张萌 Compound preparation promoting tumor compression post-operation healing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘益华等: "《栀子有效成分栀子苷的现代研究进展》", 《中国药学杂志》 *
李丰良: "《自制复方蜜唧油治疗烧伤》", 《基层医学论坛》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902669A (en) * 2016-04-29 2016-08-31 张萌 Compound preparation promoting tumor compression post-operation healing

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Application publication date: 20131009