CN103328513B - 抗ccr4抗体及其应用 - Google Patents

抗ccr4抗体及其应用 Download PDF

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Publication number
CN103328513B
CN103328513B CN201180066005.9A CN201180066005A CN103328513B CN 103328513 B CN103328513 B CN 103328513B CN 201180066005 A CN201180066005 A CN 201180066005A CN 103328513 B CN103328513 B CN 103328513B
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antibody
ccr4
antibodies
cells
seq
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Expired - Fee Related
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CN103328513A (zh
Inventor
U·B·哈格曼
R·A·格里普
H·雷厄瑟夫
S·M·基普里亚诺夫
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Oofy Technology Co ltd
Cancer Research Technology Ltd
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Affitech Research AS
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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CN201180066005.9A 2010-12-07 2011-12-07 抗ccr4抗体及其应用 Expired - Fee Related CN103328513B (zh)

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GB1020738.9 2010-12-07
GB201020738A GB201020738D0 (en) 2010-12-07 2010-12-07 Antibodies
PCT/GB2011/052421 WO2012076883A1 (en) 2010-12-07 2011-12-07 Anti ccr4 antibodies and uses thereof

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CN103328513B true CN103328513B (zh) 2016-04-27

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GB2512857A (en) 2013-04-09 2014-10-15 Cancer Res Technology Cancer biomarker
WO2015191997A1 (en) * 2014-06-12 2015-12-17 The General Hospital Corporation Anti-human chemokine (c-c motif) receptor 4 immunotoxins
AU2015282627B2 (en) 2014-06-30 2020-04-02 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
WO2016057488A1 (en) * 2014-10-06 2016-04-14 Dana-Farber Cancer Institute, Inc. Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof
PE20180774A1 (es) 2015-07-23 2018-05-07 Boehringer Ingelheim Int Compuesto que se dirige a il-23a y al factor de activacion de linfocitos b (baff) y usos de estos
CA3026474A1 (en) 2016-06-20 2017-12-28 Kymab Limited Anti-pd-l1 and il-2 cytokines
CN110494563A (zh) * 2017-01-30 2019-11-22 奥菲尔·努斯鲍姆 适用于治疗的化学实体
JP6811480B2 (ja) * 2017-02-28 2021-01-13 日本全薬工業株式会社 イヌ皮膚ｔ細胞リンパ腫細胞株
EP3626269A4 (en) 2017-05-19 2021-03-03 Shingo Maeda Method for inhibiting regulatory t cell infiltration using ccr4 inhibition and method for treating canine neoplastic disease
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