CN103301418A - Medicine composition for treating pharyngitis - Google Patents
Medicine composition for treating pharyngitis Download PDFInfo
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- CN103301418A CN103301418A CN2012100664592A CN201210066459A CN103301418A CN 103301418 A CN103301418 A CN 103301418A CN 2012100664592 A CN2012100664592 A CN 2012100664592A CN 201210066459 A CN201210066459 A CN 201210066459A CN 103301418 A CN103301418 A CN 103301418A
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Abstract
The invention discloses a pure Chinese medicine composition for treating pharyngitis and belongs to the human living need department, the medicine department, and the technical field of the curative activity of compounds or medicine preparations, divided according to the International Patent Classification (IPC). The invention aims at providing a pure Chinese medicine composition for treating pharyngitis, which is completely formulated from natural pure Chinese medicines, and free of toxic and side effects. The medicine composition is composed of the natural pure Chinese medicines, namely radix scrophulariae, oroxylum indicum, rhizoma zingiberis, cassia twig, puffball, platycodon grandiflorum, ganoderma lucidum, radix ophiopogonis, blackberry lily and liquorice without toxic and side effects in an optimized proportioning ratio. The pure Chinese medicine composition is characterized by having the effect of treating swollen sore throat, polydipsia, hoarseness and the like, and has no toxic and side effects on human body because the pure Chinese medicine ingredients of the formula have a supplementary effect. According to the novel technical scheme, the medicine composition disclosed by the invention is wide in applications in the technical field of the curative activity of medicine preparations. The pharmaceutically acceptable auxiliary materials of the medicine composition disclosed by the invention can be medicinal carriers, excipients and other additives for conventional preparations.
Description
Technical field
The present invention relates to a kind of medicine of medicine composite for curing pharyngitis, particularly a kind of pure Chinese medicine composition for the treatment of pharyngitis.
Background technology
Pharyngitis is a kind of common disease, a kind of commonly encountered diseases, the frequently-occurring disease of particularly using the too much colony of throat easily to suffer from.Pharyngitis can occur at any age, was by pharyngeal mucosa, the inflammation of submucous tissue, a kind of syndrome that often causes for upper respiratory tract infection.Different according to the length of the course of disease and pathological change character are divided into acute pharyngitis, chronic pharyngitis two large classes.
Acute pharyngitis is pharyngeal mucous membrane, and involves under the mucosa and adenoid acute inflammation, often is secondary to acute rhinitis or acute tonsil inflammation afterwards or is the part of upper respiratory tract infection.Also often be the topical manifestations of general disease or be the prodrome of acute infectious disease.
Chronic pharyngitis is mainly pharynx mucosa chronic inflammatory disease, and diffuse inflammation often is the part of upper respiratory tract chronic catarrhal inflammation, and the limitation inflammation is many inflammation with the pharynx lymphoid tissue then.Chronic pharyngitis is a kind of commonly encountered diseases, frequently-occurring disease clinically, and is relatively more obstinate in the Drug therapy of routine, and repeatedly outbreak.
For many years, the anti-pharyngitis medicine on the medical market mainly is the Western medicine of several treatment pharyngitis seldom, and clinical application is always by antibiotic such as penicillin, cephalosporin, sulfonamides and antiviral agents such as moroxydine, amantadine, moroxydine, interferon etc.Local available 1: 5000 furacillin solution or compound recipe borax solution are gargled, Du Laifen, chlohexidine, Herba Menthae slice or contain containing of iodine tablet, or antibiotic adds the hormone atomizing and sucks.Traditional Chinese medical herbal treatment such as Ephedrae Decoction are for oral administration, cow-bezoar anti-toxic bolus, and the detoxicating, relieving inflammation ball, LIUSHEN WAN is for oral administration, and local available BINGPENG SAN or XILEI SAN are blown in the pharynx.Even acupuncture cheek car, connected valleys, Shaoshang or do angle of mandible sealing.JINSANGZIHOUBAO, Lotrimin Sol Lotrimin, the Herba Pileae Scriptae throat lozenge, Wu is the medicine such as Yanyan slice too, and this class medicine ubiquity is expensive, toxic and side effects large, therapeutic effect is not remarkable.
The present invention is secret prescription handed down in the family from generation to generation, provides a kind of pharyngitis for the treatment of remarkable to the patient who suffers the pharyngitis pain constricted, has no side effect, and is cheap, and medication is convenient, for a kind of new selection has improved in consumer.
Summary of the invention
The object of the present invention is to provide a kind of pure Chinese medicine composition for the treatment of pharyngitis, prescription is reasonable in design, and medicament sources is the general medicine cheap and easy to get of clinical long-term extensive application, and is safe and effective, quality controllable.
The object of the present invention is achieved like this: prescription (taking three days with potion, the single medication amount that count more than 3 times every day) and optimum ratio are as follows:
Various compositions in this prescription spread in the market common Chinese all extensive sale, and wherein Radix Scrophulariae is clearing away heat and cooling blood; Nourishing YIN to lower pathogenic fire; Detoxicating and resolving stagnation of pathogens; Cure mainly laryngopharynx swelling and pain, excessive thirst.Semen Oroxyli property of medicine mildly bitter flavor; Sweet; Cold nature is returned through returning lung; Liver; Stomach is through the lung moistening of effect sore-throat relieving; Dispersing the stagnated liver-QI for regulating the stomach; Effect classification antitussive; The lung moistening medicine; Cure mainly the pharyngalgia sore throat; Hoarseness; Cough.Lasiosphaera Seu Calvatia is " not Lu " 1.: " acrid in the mouth is flat, nontoxic." function cures mainly: removing heat from the lung and relieving sorethroat, detoxifcation.Control the sore throat pharyngalgia, the cough with aphonia.4. " detailed outline ": " lung heat clearing, loose heat in blood, detoxifcation." can cough sore throat, epistaxis, all diseases of aphonia by clearing away lung-heat.″。Ganoderma [source] is the sporophore of On Polyporaceae Ganoderma, Ganoderma etc.[property of medicine] sweet in the mouth, property is flat.Return lung, the heart, spleen channel.[function with cure mainly] replenishing QI and blood, tranquilizing mind.Cure mainly asthenia, insomnia, dizziness, spiritlessness and weakness, chronic cough asthma.Ramulus Cinnamomi [nature and flavor] Xin Gan, temperature.1. " medicine origin ": " gas heat, acrid-sweet flavor." 2. " herbal classic is met former ": " suffering, sweet, tepor, nontoxic.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, thoracic obstruction phlegm retention.2. " medicine origin ": " " curing mainly secret formula ": loosing the interspaces of skin and muscles, induce sweat." 3. " Bencao Jingshu ": " real table is eliminating evil.Main benefitting liver and lung gas.Rhizoma Belamcandae [function cures mainly] pathogenic fire reducing, detoxifcation, loose blood, expectorant.Control the sore throat pharyngalgia, cough with dyspnea, accumulation and obstruction of sputum, carbuncle sore tumefacting virus.Radix Platycodonis [function cures mainly] is opened lung qi dispersing gas, the evacuation of pus of eliminating the phlegm.Control the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain.Radix Ophiopogonis GUIXIN, lung, stomach warp.[function with cure mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, the chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, pharyngeal diphtheria.The cards such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat.Radix Glycyrrhizae [meridian distribution of property and flavor] is sweet, and is flat.GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Especially remarkable to the curative effect of pharyngitis according to this prescription gained medicine.Several pure Chinese medicine ingredients of this prescription has complementary action, so very little to the human injury.
This medicine is natural pure Chinese medicine formula fully, has no side effect, and makes simple, easy to use.The patient just can receive good effect several times as long as slowly swallow.Be particularly suitable for the pharyngitis of using throat excessively to bring out.Clinical verification is the significant oral liquid for the treatment of pharyngitis.
The pharmaceutically acceptable adjuvant that pharmaceutical composition of the present invention comprises can be pharmaceutical carrier, excipient and other additive that conventional formulation is used.If necessary, the present invention can also comprise other active component.Pharmaceutical composition of the present invention can the dosage unit preparations oral administration, but the applicable form that orally uses can have tablet, capsule dispersed powders or granule.Can be by any known method preparation in the prior art, such compositions can comprise the reagent of one or more free sweeting agents, correctives, coloring agent and antiseptic, so that pharmaceutically attractive in appearance and agreeable to the taste preparation to be provided.But tablet comprises active component and is suitable for the nontoxic medicine excipient of tablet manufacturing.These excipient can be inert diluents, such as calcium carbonate, sodium carbonate, lactose, calcium phosphate or sodium phosphate, cellulose etc.; Granulating agent and disintegrating agent are such as corn starch or bath acid etc.; Binding agent is such as starch, gelatin or arabic gum etc.; Lubricant is such as magnesium stearate, stearic acid or Pulvis Talci etc.; Tablet can be coating not, perhaps can adopt known technology to carry out coating.Oral formulations can be hard gelatin capsule, wherein, active component and inert solid diluent, for example calcium carbonate, calcium phosphate or starch mix, and can add sweeting agent and correctives so that agreeable to the taste oral formulations to be provided.These compositionss can add antioxidant, carry out anticorrosion such as ascorbic acid, but dispersed powders is that active component is mixed with dispersant or wetting agent, suspending agent and one or more antiseptic, be suitable for preparing suitable water slurry by adding water, but also can comprise other excipient for example sweeting agent, correctives and coloring agent in the dispersed powders.
The specific embodiment
1. drug oral formula of liquid of the present invention and method for making (making 1000 milliliters)
Above-mentioned raw materials is put into decoction vessel, add water and decoct, the time got final product after boiling in 20～30 minutes, then, pour medicinal liquid into sterilization container, add again the appropriate amount of auxiliary materials sodium benzoate, mix, after the cooling, under aseptic condition, bottle, 10 milliliters every bottle, one time 10～20 milliliters, 5 times on the one.Time spent shakes up.The course for the treatment of: a week is a course for the treatment of.
2. medicinal tablet prescription of the present invention and preparation (making 1000)
Above-mentioned raw materials is put into decoction vessel, decoct, the time got final product after boiling in 20～30 minutes, leach medicinal liquid, add again decocting and endured 30～40 minutes, leach medicinal liquid, merge medicinal liquid twice, dehydration is concentrated into the silk fabric paste, adds 15% capacitive amylodextrin, mixing, 60 ℃ of oven dry are pulverized, add 1% magnesium stearate mixing, cross 20 mesh sieve granulate, tabletting, sheet weigh 0.5 gram.Instructions of taking: each 2～3, three times on the one.The course for the treatment of: a week is a course for the treatment of.
3. make tea agent prescription and preparation (making 50 bags) of medicinal bag of the present invention
Get following prescription:
With pulverizing medicinal materials, fully mix homogeneously is crossed the 60-80 mesh sieve, packs into teabag with filter paper at bag tea machine by every bag 5 gram.Instructions of taking: three bags of every days, early, middle and late each one bag.Teabag is put into thermos cup, drink after water brews 20-30 minute with sealing off.This teabag is light sweet good to eat, can drink throughout the year.The course for the treatment of: a week is a course for the treatment of.
4. medicine water decoction prescription of the present invention and preparation (making 1000 milliliters)
Above-mentioned raw materials is put into decoction vessel, add water and decoct, the time got final product after boiling in 20～30 minutes, leached medicinal liquid, added decocting again and endured 30～40 minutes, leached medicinal liquid, merged medicinal liquid twice, made 1000 milliliters.Instructions of taking: slowly take for early, middle and late minute three times, each 100 milliliters, for three days on end.The pharmaceutical factory produces, and through sterilization, sealing can be prepared into the bottled specification of cough syrup and carry out market sale.Instructions of taking: slowly take for early, middle and late minute three times, each 100 milliliters, for three days on end.The course for the treatment of: a week is a course for the treatment of.
5. medicament capsule agent prescription of the present invention and preparation (making 1000)
Above-mentioned raw materials is put into decoction vessel, add water and decoct, the time got final product after boiling in 20～30 minutes, leached medicinal liquid, add decocting again and endured 30～40 minutes, leach medicinal liquid, merge medicinal liquid twice, dehydration is concentrated into the silk fabric paste, add 20% order crude drug powder, mixing, 60 ℃ of oven dry are pulverized.This medicated powder is restrained into capsule by every explosive payload 0.4.Instructions of taking: each 2～3, three times on the one.The course for the treatment of: a week is a course for the treatment of.
Clinical efficacy data and model case:
1. Wang, the woman 23 years old, engages in educational work.Because serve as the main subject teacher of several graduating class, teaching task is very busy, and is excessive with throat, gets pharyngitis.After failing to respond to any medical treatment in hospital and clinic, took this medicine oral liquid prescription 2 days, feeling relaxed is many; Continue to take this medicine oral liquid prescription after 7 days, throat itches, feel bad transference cure uncomfortable in chest as dry as terribly hot.
2. Shandong, the man 36 years old, engages in educational work.Because will promptly train for training class suddenly, the upper time be long, and task is heavy; Physical fatigue adds with throat excessive, gets pharyngitis.After failing to respond to any medical treatment in hospital and clinic, took this liquid medicine decoct prescription 2 days, feeling relaxed is many; After continuing to take this medicine 7 water decoctions prescription day, throat itches, feel bad transference cure uncomfortable in chest as dry as terribly hot.
3. Lu, the woman, 40 years old, from art performance work.Because serve as main subject teacher's teaching of several graduating class
Task is very busy; Add to participate in and sing match, excessive with throat, got pharyngitis.After failing to respond to any medical treatment in hospital and clinic, take make tea agent prescription 2 days of this medicated bag, feeling relaxed is many; Continue to take this medicated bag and make tea agent prescription after 7 days, throat itches, feel bad transference cure uncomfortable in chest as dry as terribly hot.
4. Yin, the man 45 years old, often goes on business from sale.Since very busy fatigue, the pharyngitis of having a low resistance.Through the treatment of hospital and clinic without obvious effect, after took this tablet prescription 2 days, sensory effect is obvious; Continue to take this tablet prescription after 7 days, throat itches, feel bad transference cure uncomfortable in chest as dry as terribly hot.
5. Lee, woman, 58 years old, the administrator of the unit of being engaged in work.Although work is not very busy; But will have office hours at storeroom, move at ordinary times less, run into abrupt change of climate, throat is uncomfortable, gets on inspection pharyngitis.After failing to respond to any medical treatment in hospital and clinic, took this Drug Capsule agent prescription 2 days, feel comfortable; Continue to take this Drug Capsule agent prescription after 7 days, throat itches, feel bad transference cure uncomfortable in chest as dry as terribly hot.
Claims (6)
1. the medicine of a medicine composite for curing pharyngitis, it is characterized in that described medicine belongs to pure Chinese medicine composition, prescription is reasonable in design, and medicament sources is the general medicine cheap and easy to get of clinical long-term extensive application, and is safe and effective, quality controllable, the treatment pharyngitis is remarkable, has no side effect, and is cheap, medication is convenient, for a kind of new selection has improved in consumer.
2. the pure Chinese medicine composition for the treatment of pharyngitis as claimed in claim 1, it is characterized in that described formula range Radix Scrophulariae be the 10-30 gram, optimum ratio is that the 15-25 gram is better, Semen Oroxyli is the 10-30 gram, optimum ratio is that the 15-25 gram is better, and Rhizoma Zingiberis is the 10-30 gram, and optimum ratio is that the 15-25 gram is better, Ramulus Cinnamomi is the 10-30 gram, optimum ratio is that the 15-25 gram is better, and Lasiosphaera Seu Calvatia is the 10-20 gram, and optimum ratio is that the 15-20 gram is better, Radix Platycodonis is the 10-30 gram, optimum ratio is that the 15-25 gram is better, and Ganoderma is the 10-30 gram, and optimum ratio is that the 15-25 gram is better, be the 10-30 gram Radix Ophiopogonis, optimum ratio is that the 15-20 gram is better, and Rhizoma Belamcandae is the 10-30 gram, and optimum ratio is that the 15-20 gram is better, Radix Glycyrrhizae is the 5-15 gram, and optimum ratio is that the 6-8 gram is better.(take three days with potion, the single medication amount of counting more than 3 times every day is calculated).
3. the pure Chinese medicine composition for the treatment of pharyngitis as claimed in claim 1 or 2 is characterized in that described pure Chinese medicine composition system employing has clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, detoxicating and resolving stagnation of pathogens cures mainly laryngopharynx swelling and pain, the Radix Scrophulariae of excessive thirst, has the sore-throat relieving lung moistening, dispersing the stagnated liver-QI for regulating the stomach, relieving cough and moistening lung medicine, cure mainly the pharyngalgia sore throat, cracked Semen Oroxyli has removing heat from the lung and relieving sorethroat, detoxifcation is controlled the sore throat pharyngalgia, the Lasiosphaera Seu Calvatia that the cough with aphonia makes, have replenishing QI and blood, tranquilizing mind cures mainly asthenia, insomnia, dizziness, spiritlessness and weakness, the Ganoderma of chronic cough asthma has the diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, control exterior syndrome due to wind-cold, the Ramulus Cinnamomi of thoracic obstruction phlegm retention has pathogenic fire reducing, detoxifcation, loose blood, expectorant, control the sore throat pharyngalgia, cough with dyspnea, accumulation and obstruction of sputum, the Rhizoma Belamcandae of carbuncle sore tumefacting virus has out lung qi dispersing gas, the evacuation of pus of eliminating the phlegm.Control the exogenous cough, laryngopharynx swelling and pain, the lung abscess vomiting pus has invigorating the spleen and replenishing QI the Radix Ophiopogonis of fullness in the chest and hypochondriac pain, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong Radix Glycyrrhizae, especially remarkable to the curative effect of pharyngitis according to this prescription gained medicine.Several pure Chinese medicine ingredients of this prescription has complementary action, so very little to the human injury.
4. the pure Chinese medicine composition for the treatment of pharyngitis as claimed in claim 1 or 2, it is characterized in that described pure Chinese medicine composition system adopts natural pure Chinese medicine formula, have no side effect, cheap, medication easily Chinese medicine rational formula is made, and the patient just can receive good effect several times as long as slowly swallow.Be particularly suitable for the pharyngitis of using throat excessively to bring out.Clinical verification is the significant oral liquid for the treatment of pharyngitis.
5. the pure Chinese medicine composition for the treatment of pharyngitis as claimed in claim 1 or 2 is characterized in that the described pharmaceutically acceptable adjuvant that comprises can be pharmaceutical carrier, excipient and other additive that conventional formulation is used.If necessary, the present invention can also comprise other active component.Pharmaceutical composition of the present invention can the dosage unit preparations oral administration, but the applicable form that orally uses can have tablet, capsule dispersed powders or granule.
6. the pure Chinese medicine composition for the treatment of pharyngitis as claimed in claim 1 or 2, can be by any known method preparation in the prior art, such compositions can comprise the reagent of one or more free sweeting agents, correctives, coloring agent and antiseptic, so that pharmaceutically attractive in appearance and agreeable to the taste preparation to be provided.But tablet comprises active component and is suitable for the nontoxic medicine excipient of tablet manufacturing.These excipient can be inert diluents, such as calcium carbonate, sodium carbonate, lactose, calcium phosphate or sodium phosphate, cellulose etc.; Granulating agent and disintegrating agent are such as corn starch or bath acid etc.; Binding agent is such as starch, gelatin or arabic gum etc.; Lubricant is such as magnesium stearate, stearic acid or Pulvis Talci etc.; Tablet can be coating not, perhaps can adopt known technology to carry out coating.Oral formulations can be hard gelatin capsule, wherein, active component and inert solid diluent, for example calcium carbonate, calcium phosphate or starch mix, and can add sweeting agent and correctives so that agreeable to the taste oral formulations to be provided.These compositionss can add antioxidant, carry out anticorrosion such as ascorbic acid, but dispersed powders is that active component is mixed with dispersant or wetting agent, suspending agent and one or more antiseptic, be suitable for preparing suitable water slurry by adding water, but also can comprise other excipient for example sweeting agent, correctives and coloring agent in the dispersed powders.
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| CN2012100664592A CN103301418A (en) | 2012-03-13 | 2012-03-13 | Medicine composition for treating pharyngitis |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101167947A (en) * | 2007-09-20 | 2008-04-30 | 吴月 | Traditional Chinese medicine for treating acute pharyngitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101167947A (en) * | 2007-09-20 | 2008-04-30 | 吴月 | Traditional Chinese medicine for treating acute pharyngitis |
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Application publication date: 20130918 |