CN103301251B - Traditional Chinese medicine composition for preventing and cow treating mastitis - Google Patents
Traditional Chinese medicine composition for preventing and cow treating mastitis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating cow mastitis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-15 parts of chrysanthemum, 2-4 parts of red flower, 3-5 parts of folium isatidis, 3-7 parts of moutan bark, 1-3 parts of Cacumen biotae, 3-5 parts of mint, 3-5 parts of folium artemisiae argyi, 5-8 parts of chitosan and 2-3 parts of fresh carrot. By utilizing the traditional Chinese medicine composition provided by the invention, the occurrence of cow mastitis is effectively prevented, the health situation of cows is improved, the influence of diseases such as mastitis to milk output and milk quality is avoided, and the composition has certain curative effect on the mastitis, and in particular recessive mastitis. By utilizing the traditional Chinese medicine composition, the economic benefits in cow breeding are greatly increased, and the unbeneficial influence of antibiotic use to the milk quality and the cow health is avoided.
Description
Technical field
The invention belongs to drug world, relate to a kind of Chinese medicine composition for preventing milk cattle cultivating process mastitis to occur.
Background technology
Mastitis, particularly recessive mastitis is a kind of cystic hyperplasia of breast that Lactation of Dairy Cow phase sickness rate is very high, can make to suffer from bovine lactation function and give milk sharply to decline, and causes the imbalance of milch cow Reproductive Performance, the commonly encountered diseases and the frequently-occurring disease that become vast cattle farm, seriously restricting the development of dairy.According to statistics, there is a mastitis in milch cow, and milk yield on average declines 8%, and the lighter declines 5%, and severe one can reach 25%～40%.Have at least Yi Geru district infected the cow of the U.S. 30% ~ 70%, because of the generation of primary disease, lose approximately 2,000,000,000 dollars every year, Japan reaches 500,000,000 dollars.The incidence rate of China's mammitis of cow is higher, and the survey showed that for Yuan Yonglong etc., clinic mastitis sickness rate average out to 33.41%, and latent mammitis average positive rate is 73.91%, newborn chamber prevalence is 44.74%.Antibiotic is listed in decades in to the choice drug for the treatment of mastitis all over the world, due to prolonged and repeated use, bring series of problems, as Resistant strain increases, endocrine dysfunction, antibiotic remains and residue of veterinary drug exceed standard etc., badly influence human health.Along with China joined WTO, consumers in general require more and more higher to milk quality, propose the requirement of antibiotic-free milk, noresidue milk.
For the generation of mastitis, conventional Therapeutic Method has at present: for Su Jie, penicillin, streptomycin breast chamber are injected in conjunction with GONGYINGSAN for oral administration and Adlerika hot compress breast affected part, and treatment Mammitis of cattle, has obtained good therapeutic effect.The thin sulfur cream of the use Chinese-western medicine preparation breast applicationes such as Li Peilin are treated acute mammitis of cow and are all cured.Ma Shudong etc. are for oral administration with breast Sweeling-eliminating medicine powder, first treat 153 examples in conjunction with specially good effect rice, and cure rate is 85.6%.Xie Caifeng etc. adopt and pour in conjunction with gentamycin, 654-2 acupoint injection therapy with propolis nipple clinic mastitis, and 5% levamisole hydrochloride is main Comprehensive Treatment test, result test group clinic mastitis breast district cure rate 91.67%, total effective rate 100%; Matched group total effective rate 42.86%; Latent mammitis breast district cure rate 66.67%, total effective rate 66.67%.Lin Zhenxiang adopts the anti-Fructus Arctii soup of chaste tree for oral administration, externally applied herbal medicine, method treatment milch cow clinic mastitis 66 examples such as papillary duct injection of antibiotics, and cure rate 84.3%, effective percentage is 95.3%.The discovery Chinese-western medicine preparations such as Gu Huijuan " powerful raw " are better than single levamisole to the therapeutic effect of bovine subclinical mastitis.Chinese medicine compound, single Herba Taraxaci, gentamycin sulfate and procaine hydrochloride for Zhu Guangdao etc., Houhai acupoint injection and levamisole hydrochloride coordinate 4 kinds of method treatment latent mammitises of Herba Houttuyniae injectio intramuscular injection, and result shows that it is this sick best approach for the treatment of that levamisole coordinates Herba Houttuyniae injectio intramuscular injection and Chinese medicine compound.
But, at present for this disease of mastitis, be main mainly with treatment, but in the time that this disease occurs, the health on milch cow and lactogenic produced important impact, seldom sees the Chinese medicine composition for preventing mammitis of cow.
Summary of the invention
For the above-mentioned problems in the prior art, the present invention aims to provide a kind of Chinese medicine composition that prevents mammitis of cow.It is primary raw material that this Chinese medicine composition is selected multiple Chinese herbal medicine, determines the proportion relation between each Chinese herbal medicine through repetition test, and mastitis is had to good preventive effect, and selected raw material is natural harmless, can not exert an influence to dairy food quality and health.
For solving the problems of the technologies described above, the present invention adopts following technological means:
A Chinese medicine composition that prevents mammitis of cow, is characterized in that, is made up of the raw material of following weight portion: Flos Chrysanthemi 10-15 part, Flos Carthami 2-4 part, Folium Isatidis 3-5 part, Cortex Moutan 3-7 part, Cacumen Platycladi 1-3 part, Herba Menthae 3-5 part, Folium Artemisiae Argyi 3-5 part, chitosan 5-8 part, fresh carrot 2-3 part.
Preferably, made by the raw material of following weight portion: 13 parts of Flos Chrysanthemis, 3 parts, Flos Carthami, 4 parts of Folium Isatidiss, 5 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 4 parts of Herba Menthaes, 4 parts of Folium Artemisiae Argyis, 7 parts of chitosans, 2 parts of fresh carrots.
All right, preferably, made by the raw material of following weight portion: 15 parts of Flos Chrysanthemis, 2 parts, Flos Carthami, 3 parts of Folium Isatidiss, 4 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 5 parts of Herba Menthaes, 3 parts of Folium Artemisiae Argyis, 6 parts of chitosans, 3 parts of fresh carrots.
A method of preparing the Chinese medicine composition of described prevention mammitis of cow, comprises the following steps:
(1) take by weight raw material;
(2) Flos Chrysanthemi taking in step (1), Flos Carthami, Folium Isatidis, Cortex Moutan, Cacumen Platycladi, Herba Menthae and Folium Artemisiae Argyi are mixed, add the water of 3 ~ 5 times of quality of mixture, decoct 1-3 hour, filtration, the cooling decoction liquor that obtains, be concentrated into 30% of decoction liquor volume, obtain concentrated solution;
(3) by the chitosan taking in step (1), join in 50-65 DEG C of warm water of its 3 times of quality and dissolve, make the chitosan solution that concentration is 25wt%;
(4) the fresh carrot beater taking in step (1) is pulled an oar, obtain fresh carrot juice;
(5) the fresh carrot juice of concentrated solution step (2) being made, the chitosan solution that step (3) obtains, step (4) acquisition mixes, and stirs, and packs, and makes the Chinese medicine composition of prevention mammitis of cow of the present invention.
The application process of the Chinese medicine composition of prevention mammitis of cow of the present invention is: the Chinese medicine composition of prevention mammitis of cow of the present invention is evenly applied at every turn after adopting milk to the cow breast surface cleaning up; it can form protecting film in breast surface, long-term continuous and effective.
The Chinese medicine composition tool of prevention mammitis of cow of the present invention has the following advantages and beneficial effect:
First, in Chinese medicine composition of the present invention, be added with chitosan, it has good film property, this Chinese medicine composition that contains chitosan can be in cow breast surface film forming effectively, form long-effective protection, and selected Chinese medicine ingredients is common Chinese medicine in the present invention, can cause residual and affect the mankind's health; Further, this Chinese medicine composition can maintain a period of time after being coated in cow breast surface, be conducive to absorption and the utilization of effective ingredient, and chitosan has certain facilitation for the absorption of effective ingredient; In addition, fresh carrot juice not only has multivitamin composition, and its color is vivid, can effectively indicate the breast of smearing medicine, effectively avoid medicine repeat smear, increase work efficiency.
Secondly, Chinese medicine composition of the present invention has mainly been selected natural, safe medicinal herb components, follow the preparation principle of " monarch ", kind and the optimum amount of Chinese herbal medicine have finally been determined through repetition test and checking, make wherein Synergistic between various Chinese medicine ingredients, mutually promote, reached the technique effect of fabulous prevention mammitis of cow.Wherein selected Flos Chrysanthemi, has effect of heat-clearing and toxic substances removing, dispelling wind improving eyesight, and its external is inhibited for staphylococcus aureus, beta hemolytic streptococcus, in the situation of high concentration, uses and also has certain antivirus action; Flos Carthami, has another name called Flos Carthami, has effect of the lactogenesis of invigorating blood circulation, stasis-dispelling and pain-killing, can be for the treatment of the diseases such as congestion pain relieving, carbuncle, traumatic injury; Folium Isatidis, has effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, its decocting liquid to multiple pathogenic microorganism such as dysentery bacterium, meningococcus, spirillums by suppressing and killing action; Cortex Moutan, has effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, and its water extract has antibacterial action to White staphylococcus, bacillus subtilis, Bacillus typhi, escherichia coli, bacillus pyocyaneus etc.; Cacumen Platycladi, has effect of cooling blood for hemostasis, and various pathogens is had to good inhibition and killing action; Herba Menthae, contains multiple volatile oil, has wind-dispelling heat-dissipating, wards off effect of dirty removing toxic substances, and external can be benumbed teleneuron, anti-inflammatory analgetic; Folium Artemisiae Argyi, has effect of expelling cold and dampness, hemostasis, also has certain bacteriostasis, and being used in conjunction with of its ZHONGJUHUA, Herba Menthae and Folium Artemisiae Argyi, has greatly played the effect of Synergistic.
Adopt Chinese medicine composition of the present invention can effectively prevent the generation of mammitis of cow, improve the health status of milch cow, avoid generation because of diseases such as the mastitiss impact on milk yield and dairy food quality, and to a certain extent mastitis is had to certain therapeutical effect, particularly latent mammitis.Adopt Chinese medicine composition of the present invention, greatly improved the economic benefit of milk cattle cultivating, and can avoid antibiotic to use the adverse effect to dairy food quality and milk cow health generation.
Detailed description of the invention
embodiment 1: a kind of Chinese medicine composition that prevents mammitis of cow, it is characterized in that, made by the raw material of following weight portion: 13 parts of Flos Chrysanthemis, 3 parts, Flos Carthami, 4 parts of Folium Isatidiss, 5 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 4 parts of Herba Menthaes, 4 parts of Folium Artemisiae Argyis, 7 parts of chitosans, 2 parts of fresh carrots.Its preparation method comprises the following steps:
(1) take by weight raw material;
(2) Flos Chrysanthemi taking in step (1), Flos Carthami, Folium Isatidis, Cortex Moutan, Cacumen Platycladi, Herba Menthae and Folium Artemisiae Argyi are mixed, add the water of 3 ~ 5 times of quality of mixture, decoct 1-3 hour, filtration, the cooling decoction liquor that obtains, be concentrated into 30% of decoction liquor volume, obtain concentrated solution;
(3) by the chitosan taking in step (1), join in 50-65 DEG C of warm water of its 3 times of quality and dissolve, make the chitosan solution that concentration is 25wt%;
(4) the fresh carrot beater taking in step (1) is pulled an oar, obtain fresh carrot juice;
(5) the fresh carrot juice of concentrated solution step (2) being made, the chitosan solution that step (3) obtains, step (4) acquisition mixes, and stirs, and packs, and makes the Chinese medicine composition of prevention mammitis of cow of the present invention.
embodiment 2: a kind of Chinese medicine composition that prevents mammitis of cow, it is characterized in that, made by the raw material of following weight portion: 15 parts of Flos Chrysanthemis, 2 parts, Flos Carthami, 3 parts of Folium Isatidiss, 4 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 5 parts of Herba Menthaes, 3 parts of Folium Artemisiae Argyis, 6 parts of chitosans, 3 parts of fresh carrots.Preparation method is with embodiment 1.
embodiment 3: zoopery
In milk cattle cultivating base, Tianjin, choose 60 of milch cows that suffer from latent mammitis through being accredited as, it is slightly red and swollen that wherein said milch cow all shows as breast, and in milk, cyton cell number is higher, and milk yield is relatively low.Above-mentioned milch cow is divided into 6 groups at random, wherein organizes 1 for blank group, it is not carried out to any processing; Group 2,3 is experimental group, smears respectively the Chinese medicine composition of embodiment 1,2 on cow breast surface, smears after adopting milk at every turn; Group 4,5 is contrast experiment's group, smears respectively the Chinese medicine composition of embodiment 1,2 on cow breast surface, smears after adopting milk at every turn; Group 6 is medication therapy groups, adopts traditional penicillin, streptomycin breast chamber to inject in conjunction with the method for GONGYINGSAN for oral administration and Adlerika hot compress breast affected part and treat, until disease disappears.Whole duration of experiment 25 days, has studied the parameter index such as average daily milk yield, Ruzhong somatic number of duration of test, and the state of development of disease, and concrete outcome sees the following form 1.
table 1 milch cow animal test results
A. comparative experimental example 1: a kind of Chinese medicine composition, made by the raw material of following weight portion: 13 parts of Flos Chrysanthemis, 3 parts, Flos Carthami, 4 parts of Folium Isatidiss, 5 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 3 parts of chitosans, 2 parts of fresh carrots.Preparation method is with embodiment 1.
B. comparative experimental example 2: a kind of Chinese medicine composition that prevents mammitis of cow, it is characterized in that, made by the raw material of following weight portion: 5 parts of Flos Chrysanthemis, 3 parts, Flos Carthami, 1 part of Folium Isatidis, 1 part of Cortex Moutan, 1 part of Cacumen Platycladi, 7 parts of Herba Menthaes, 2 parts of Folium Artemisiae Argyis, 3 parts of chitosans, 1 part of fresh carrot.Its preparation method is with embodiment 1.
Shown by above zooperal result, herbal composite of the present invention further develops, worsens as serious mastitis disease has certain preventive effect for mammitis of cow initial stage disease, namely can prevent further developing of mastitis; In addition, this Chinese medicine composition has certain healing effect for latent mammitis, and compare traditional method, it can't affect the quality of milk, and avoid the long-term decline of the milk yield that the destruction of pouring-in therapeutic modality to breast tissue and traditional treatment mode cause.
In addition, the present invention also chooses large-scale milch cow colony, random point two groups, wherein smear the Chinese medicine composition of the embodiment of the present invention 1 for one group, another group, for blank, does not process, through long-term observation surface, the mammitis of cow sickness rate that is coated with the embodiment of the present invention 1 Chinese medicine composition is only 5%, and the sickness rate of blank group is up to 45%, and particularly hot sickness rate in summer is very high.It illustrates that Chinese medicine composition of the present invention can prevent the generation of mastitis effectively to a certain extent.
In Hebei, Inner Mongol and Pekinese's scale dairy cow farm test, and also all obtained extraordinary effect, the economic benefit of milk cattle cultivating has improved 5 ~ 10% left and right.
Raw material of the present invention all can be bought from the market.Disclosed is above only specific embodiments of the invention, but the present invention is not limited thereto, and the changes that any person skilled in the art can think of, within all should dropping on protection scope of the present invention.
Claims (5)
1. a Chinese medicine composition that prevents mammitis of cow, is characterized in that, is made up of the raw material of following weight portion: Flos Chrysanthemi 10-15 part, Flos Carthami 2-4 part, Folium Isatidis 3-5 part, Cortex Moutan 3-7 part, Cacumen Platycladi 1-3 part, Herba Menthae 3-5 part, Folium Artemisiae Argyi 3-5 part, chitosan 5-8 part, fresh carrot 2-3 part;
The preparation method of the Chinese medicine composition of described prevention mammitis of cow comprises the following steps:
(1) take by weight raw material;
(2) Flos Chrysanthemi taking in step (1), Flos Carthami, Folium Isatidis, Cortex Moutan, Cacumen Platycladi, Herba Menthae and Folium Artemisiae Argyi are mixed, add the water of 3 ~ 5 times of quality of mixture, decoct 1-3 hour, filtration, the cooling decoction liquor that obtains, be concentrated into 30% of decoction liquor volume, obtain concentrated solution;
(3) by the chitosan taking in step (1), join in 50-65 DEG C of warm water of its 3 times of quality and dissolve, make the chitosan solution that concentration is 25wt%;
(4) the fresh carrot beater taking in step (1) is pulled an oar, obtain fresh carrot juice;
(5) the fresh carrot juice of concentrated solution step (2) being made, the chitosan solution that step (3) obtains, step (4) acquisition mixes, stirs, and packaging, the Chinese medicine composition of the prevention mammitis of cow described in making.
2. the Chinese medicine composition of prevention mammitis of cow according to claim 1, is characterized in that, is made up of the raw material of following weight portion: 13 parts of Flos Chrysanthemis, 3 parts, Flos Carthami, 4 parts of Folium Isatidiss, 5 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 4 parts of Herba Menthaes, 4 parts of Folium Artemisiae Argyis, 7 parts of chitosans, 2 parts of fresh carrots.
3. the Chinese medicine composition of prevention mammitis of cow according to claim 1, is characterized in that, is made up of the raw material of following weight portion: 15 parts of Flos Chrysanthemis, 2 parts, Flos Carthami, 3 parts of Folium Isatidiss, 4 parts of Cortex Moutans, 2 parts of Cacumen Platycladis, 5 parts of Herba Menthaes, 3 parts of Folium Artemisiae Argyis, 6 parts of chitosans, 3 parts of fresh carrots.
4. the Chinese medicine composition of prevention mammitis of cow claimed in claim 1, it is characterized in that, the using method of this Chinese medicine composition is: the Chinese medicine composition of described prevention mammitis of cow is evenly applied at every turn after adopting milk to the cow breast surface cleaning up.
5. a method of preparing the Chinese medicine composition of the prevention mammitis of cow described in claim 1 ~ 3 any one, is characterized in that, comprises the following steps:
(1) take by weight raw material;
(2) Flos Chrysanthemi taking in step (1), Flos Carthami, Folium Isatidis, Cortex Moutan, Cacumen Platycladi, Herba Menthae and Folium Artemisiae Argyi are mixed, add the water of 3 ~ 5 times of quality of mixture, decoct 1-3 hour, filtration, the cooling decoction liquor that obtains, be concentrated into 30% of decoction liquor volume, obtain concentrated solution;
(3) by the chitosan taking in step (1), join in 50-65 DEG C of warm water of its 3 times of quality and dissolve, make the chitosan solution that concentration is 25wt%;
(4) the fresh carrot beater taking in step (1) is pulled an oar, obtain fresh carrot juice;
(5) the fresh carrot juice of concentrated solution step (2) being made, the chitosan solution that step (3) obtains, step (4) acquisition mixes, stirs, and packaging, the Chinese medicine composition of the prevention mammitis of cow described in making.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2613470C2 (en) * | 2015-06-30 | 2017-03-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Южно-Уральский государственный аграрный университет"(ФГБОУ ВО Южно-Уральский ГАУ) | Method of reduction of heavy metal content of cow's milk |
| CN105918631A (en) * | 2016-04-28 | 2016-09-07 | 青岛海之星生物科技有限公司 | Feed additive for preventing cow subclinical mastitis and preparation method thereof |
| CN105998323A (en) * | 2016-05-27 | 2016-10-12 | 青岛绿曼生物工程有限公司 | Film-forming pharmaceutical composition for preventing and treating cow mastitis as well as application and preparation method of pharmaceutical composition |
| CN108653487A (en) * | 2018-06-27 | 2018-10-16 | 张家口万全区科泰生物科技有限公司 | It is a kind of enhancing milk cow immunity active peptide and its application |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1883552A (en) * | 2006-05-20 | 2006-12-27 | 姜川 | A Chinese medicine for treating mastopathy and method for preparing same |
| CN101134080B (en) * | 2006-08-30 | 2011-09-07 | 瑞普（天津）生物药业有限公司 | Compound traditional Chinese powder medicine for treating acute mastitis for cows |
| CN101057858A (en) * | 2007-04-24 | 2007-10-24 | 史义林 | Protecting agent for preventing and curing cow and goat mastitis and its preparation method |
| KR101156082B1 (en) * | 2010-02-09 | 2012-06-20 | 주식회사 제일바이오 | Composition for treating bovine mastitis |
| AU2013100016A4 (en) * | 2013-01-08 | 2013-02-07 | Meredith Claire Patten | Composition For Alleviating The Symptoms Of Mastitis |
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