CN105918631A - Feed additive for preventing cow subclinical mastitis and preparation method thereof - Google Patents

Abstract

The invention discloses a feed additive for preventing cow subclinical mastitis and a preparation method thereof. The feed additive is prepared from 9-12 parts by weight of fructus forsythia, 15-30 parts by weight of mangosteen shells, 30-40 parts by weight of fresh Malabar spinach, 20-30 parts by weight of fresh enteromorpha prolifera, 2-4 parts by weight of clam powder, 6-9 parts by weight of snake bramble seeds, 6-9 parts by weight of root of root of Polygonum divaricatum L., 4-7 parts by weight of impatiens noli-tangere, 3-5 parts by weight of moutan bark, 9-12 parts by weight of radix angelicae dahuricae, 15-20 parts by weight of fresh purslane, 10-15 parts by weight of fresh ginseng fruits, 5-8 parts by weight of roasted radix licorice, 8-10 parts by weight of jack fruit pulp and 9-12 parts by weight of leaves and fruits of Eucalyptus globules. The feed additive improves a milk yield, reduces cow mastitis morbidity, supplies vitamins and trace elements for cows, effectively prevents antibiotic and hormone use, prevents milk product pollution and ensures milk product eating safety.

Description

A kind of feed additive preventing bovine subclinical mastitis and preparation method thereof

Technical field

The present invention relates to a kind of feed additive, particularly to a kind of feedstuff preventing bovine subclinical mastitis Additive and preparation method thereof.

Background technology

Mastitis is the one common property disease of milch cow, is generally divided into clinic mastitis and latent mammitis Two classes.Owing to latent mammitis symptom is slight, is often ignored by people, not only have a strong impact on ill cattle Milk yield, milk-quality, prolongation post-partum estrus and pregnant time, and easily spread and epidemic in cows, give Dairy causes heavy losses, and milk quality changes simultaneously, goes back entail dangers to human health.Therefore, The meaning that active prevention controls bovine subclinical mastitis is the most great.The economic loss that mastitis causes includes Milk Production declines, succedaneum expense increases, raw material milk abandons, medication expense, veterinary and labour force's expense With increase etc..It is generally believed that in the economic loss that mastitis causes, milk yield reduce the damage caused Mistake accounts for 70%, due to ill eliminated in advance account for 14%, discarded milk accounts for 7%, and treatment and veterinary's expense account for 8%.In cows, the mastitis of about 90% belongs to latent mammitis, the economic loss thus resulted in Account for the 10%-11% of lactating cow yearly productive capacity.According to American National mastitis committee, recessive breast The newborn district of scorching each infection, 636-773kg of giving milk less per lactation period.The nineties in 20th century, the U.S. is because of breast Annual about 185 dollars of economic loss every the cattle that room inflammation causes, the most therefore loss 10.8 hundred million dollars.Hidden Property mastitis not only makes milk yield reduce, and makes the quality of milk decline, valine, methionine, different 6 kinds of TEAAs such as propylhomoserin, leucine, phenylalanine, lysine are also by average 2.238g/100ml (certified milk) is down to 1.759g/100ml, reduces 21%.In addition, lactose, casein, fat, Na, P, etc. the content of beneficiating ingredient all reduce or substantially reduce, heat stability has declined.

At present, dairy farmer's treatment to mammitis of cow, it is common to use antibiotic, although achieve preferably Effect, but the thing followed be drug residue problem, the resistance problems of pathogen, environmental problem with And the series of problems such as human health.

Summary of the invention

It is an object of the invention to provide a kind of feed additive preventing bovine subclinical mastitis and preparation thereof Method, this feed additive can improve milk yield, reduces the sickness rate of mammitis of cow, the most fully Supplement the vitamin needed for milch cow and trace element, be prevented effectively from the use of the material such as antibiotic, hormone, Avoid the pollution of dairy products, it is ensured that the edible safety of dairy products.

To achieve these goals, the technical scheme that the present invention provides is as follows:

A kind of feed additive preventing bovine subclinical mastitis, makes the raw material group of described feed additive Become and parts by weight are: Fructus Forsythiae 9-12 part, mangosteen skin 15-30 part, Herba basellae rubrae fresh goods 30-40 part, waterside Tongue fresh goods 20-30 part, Pulvis concha Mactrae 2-4 part, Semen Caesalpiniae Minacis 6-9 part, Radix polygoni divaricati 6-9 part, Flos seu Radix Impatientis nolitangeris 4-7 part, Cortex Moutan 3-5 part, Radix Angelicae Dahuricae 9-12 part, Herba Portulacae fresh goods 15-20 part；Herba Herminii fresh goods 10-15 Part, Radix Glycyrrhizae Preparata 5-8 part, Fructus Artocarpi Heterophylli sarcocarp 8-10 part, Eucalyptus globulus Labill 9-12 part.

Further, make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 9 parts, Mangosteen skin 15 parts, Herba basellae rubrae fresh goods 30 parts, Entermorpha fresh goods 20 parts, Pulvis concha Mactrae 2 parts, Semen Caesalpiniae Minacis 6 parts, Radix polygoni divaricati 6 parts, Flos seu Radix Impatientis nolitangeris 4 parts, Cortex Moutan 3 parts, the Radix Angelicae Dahuricae 9 parts, Herba Portulacae fresh goods 15 parts；People Ginseng fruit fresh goods 10 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Artocarpi Heterophylli sarcocarp 8 parts, Eucalyptus globulus Labill 9 parts.

Further, make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 12 parts, Mangosteen skin 30 parts, Herba basellae rubrae fresh goods 40 parts, Entermorpha fresh goods 30 parts, Pulvis concha Mactrae 4 parts, Semen Caesalpiniae Minacis 9 parts, Radix polygoni divaricati 9 parts, Flos seu Radix Impatientis nolitangeris 7 parts, Cortex Moutan 5 parts, the Radix Angelicae Dahuricae 12 parts, Herba Portulacae fresh goods 20 parts； Herba Herminii fresh goods 15 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Artocarpi Heterophylli sarcocarp 10 parts, Eucalyptus globulus Labill 12 parts.

Further, make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 11 parts, Mangosteen skin 22 parts, Herba basellae rubrae fresh goods 35 parts, Entermorpha fresh goods 25 parts, Pulvis concha Mactrae 3 parts, Semen Caesalpiniae Minacis 7 parts, Radix polygoni divaricati 7 parts, Flos seu Radix Impatientis nolitangeris 5 parts, Cortex Moutan 4 parts, the Radix Angelicae Dahuricae 11 parts, Herba Portulacae fresh goods 17 parts； Herba Herminii fresh goods 17 parts, Radix Glycyrrhizae Preparata 6 parts, Fructus Artocarpi Heterophylli sarcocarp 9 parts, Eucalyptus globulus Labill 10 parts.

The preparation method of above-mentioned a kind of feed additive preventing bovine subclinical mastitis, including following step Rapid:

(1) Fructus Forsythiae, Semen Caesalpiniae Minacis, Radix polygoni divaricati, Flos seu Radix Impatientis nolitangeris, Cortex Moutan, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Eucalyptus globulus Labill Pulverizing to obtain 50 mesh mixed-powders, gained mixed-powder adds the water soaking 1 hour of gross mass multiple 5 times, Slow fire boiling 1 hour, crosses 500 mesh drainage screens and obtains filtrate, again add mixed-powder gross mass after decoction The water soaking that multiple is 5 times 0.5 hour, slow fire boiling is crossed 500 mesh drainage screens after 1 hour and is obtained filtrate, closes And twice gained filtrate is cooled to room temperature, standby；

(2) mangosteen skin, Herba basellae rubrae fresh goods, Entermorpha fresh goods, Herba Portulacae fresh goods, Herba Herminii fresh goods, Fructus Ananadis comosi Mamoncillo meat is cleaned, and adds step (1) gained filtrate and grinds pulping；

(3) step (2) gained slurry mixes with Pulvis concha Mactrae, carries out homogeneous in addition homogenizer, homogeneous Temperature 15 ± 2 DEG C, 13 ± 2 minutes time, obtains batch mixing；

(4) step (3) gained batch mixing is carried out vacuum lyophilization and obtain mixed-powder；

(5) to step (4) gained mixed-powder ultraviolet sterilization 25 ± 5 minutes, milch cow must be prevented hidden The feed additive of property mastitis.

Using method: the feed additive of the present invention is added in concentrated feed, each former in described concentrated feed The mass percent of material is: soybean cake 32.7%-35.5%, salt 1%-2%, calcium phosphate 0.8%-1.2%, this Bright feed additive 2.7%-3.6%, surplus is Semen Maydis.

The raw materials used characteristic of the present invention is as follows:

Fructus Forsythiae: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens, modern medicine study confirms, Fructus Forsythiae concentrates Decoct has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bar Bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.；

Mangosteen skin: slightly cool in nature, diminishing inflammation, removing pain, heat-clearing and toxic substances removing, dampness removing and anti-diarrhea effect, mangosteen skin rich in Tannic acid, tannic acid is to clinical common isolated strains such as staphylococcus aureus, staphylococcus epidermidis, molten Blood staphylococcus, enterococcus faecalis, enterococcus faecalis, escherichia coli, Klebsiella Pneumoniae, Aerugo vacation list Born of the same parents bacterium, Acinetobacter bauamnnii etc. have antibacterial action and can affect biomembranous formation, and mangosteen skin is rich in former Anthocyanidin, procyanidin is a kind of bioflavonoids having special molecular structure, is the most in the world The removing maximally effective Natural antioxidant of people's interior free yl generally acknowledged, procyanidin can strengthen blood capillary Pipe, tremulous pulse and vein blood vessel, it has effect that detumescenceization is become silted up, the drag reduction of blood capillary and permeability Improving, make cell be easier to absorb nutrient and get rid of refuse, procyanidin can be with water-soluble in scavenger cell film Property and fat-soluble free radical, therefore, it is suppressed that discharge some enzyme go injure capillary wall process, Procyanidin suppression produces the enzyme that histamine needs, and prevents from generating histamine, thus dephlogistication；

Herba basellae rubrae: nutrient content is the abundantest, the especially constituent content such as calcium, ferrum is the highest, raw rich in dimension Element A, vitamin C, vitamin B group and protein, and heat is low, lean, and the most edible have fall Blood pressure, the liver benefiting, clearing away heat and cooling blood, diuresis, preventing the effects such as constipation, the calcium content of Herba basellae rubrae is the highest, and Oxalic acid content is extremely low, is the preferred economic dish replenished the calcium, simultaneously rich in a kind of mucus in Herba basellae rubrae dish leaf, right Anti-cancer and cancer-preventing has well effect；

Entermorpha: be a kind of large-scale chlorella, be commonly called as Enteromorpha clathrata (Roth) Greville, green laver etc., for Chlorophyta Ulvales Ulvaceae The algae of Enteromorpha, common are Enteromorpha linza, Enteromorpha compressa(L.) Grev., Enteromorpha clathrata (Roth) Greville, intestinal Entermorpha etc..Entermorpha For the wild chlorella in the beach of coastal waters, its natural propagation ability is strong especially, and yield is huge.China sea Chlorella (mainly Entermorpha) resource of territory particularly Area of The East China Sea is the abundantest.Entermorpha frond is dark green, taste Road is delicious, nutritious, also has higher medical value, and developing and utilizingpotentiality is huge.: Entermorpha is rich Carbohydrate containing, protein, crude fibre and mineral, simultaneously possibly together with fat and vitamin.At waterside In tongue protein, amino acid classes is complete, it is necessary to amino acid content is higher, wherein the restriction of Enteromorpha linza Aminoacid is lysine；The limiting amino acid of Enteromorpha clathrata (Roth) Greville is methionine.In the fatty acid composition of Entermorpha, many The content of unsaturated fatty acid, monounsaturated fatty acid and satisfied fatty acid is respectively 50.5%, 12.7% With 36.8%, including the odd carbon fatty acid of nearly 4%.Therefore Entermorpha is high protein, high meals Food fiber, low fat, low-yield, and the natural ideal nutritional food of rich in mineral substances and vitamin is former Material, China cures mat and experience among the people is thought, large-scale chlorella not only has abundant nutritive value, and has There are heat-clearing and toxic substances removing, anti-inflammation, cholesterol reducing, enhancing human body immunity power, hard masses softening and resolving, swelling diuretic And change effect of disease.According to " with breath occupy diet spectrum " record: Entermorpha " gallbladder that disappears, the scrofula goiter that disappears, let out swollen, Reduce phlegm, control being not acclimatized "；Compendium of Material Medica note have Entermorpha " burn end nasal insufflation and stop epistaxis, soup is unrestrained smash deposited The back of the hand swells and ache "；Coastal spreading so far controls acute and chronic gastroenteritis with ulva class decoction, and Guangdong is then by Entermorpha Relieve summer heat detoxification beverage.Entermorpha, rich in polysaccharide, accounts for Sargassum dry weight more than 50%, has biological widely living Property and medicinal function (blood fat reducing, antitumor, antiviral, antibacterial, regulation immunity, antioxidation, anti- Fatigue and blood sugar lowering etc.), can be widely applied to medicine, health food and bread and cheese；

Pulvis concha Mactrae: salty in the mouth, cold in nature, there is heat clearing away, reduce phlegm dampness removing, effect of softening the hard mass, is usually used in stomachache, Phlegm retention is breathed with cough, aqueous vapor edema, urinary obstruction, seminal emission, nebulousurine, metrorrhagia, leukorrhagia, carbuncle, goiter, Scalding, Pulvis concha Mactrae is also rich in calcareous and mineral；

Semen Caesalpiniae Minacis: property is bitter, taste is trembled with fear, and dissipating blood stasis, pain relieving, heat clearing away, dries, with controlling hiccup, dysentery, pouring Turbid, hematuria, traumatic injury；

Radix polygoni divaricati: acid is sweet, temperature, cold relieving, the kidney warming, control colic of cold type, scrotum is perspired, to golden yellow Fructus Vitis viniferae In coccus, Bacillus typhi, paratyphoid bacillus A, Bacillus paratyphosus B, escherichia coli O88B7, Song Shigella flexneri, bacterium flexneri all have fungistatic effect；

Flos seu Radix Impatientis nolitangeris: sweet in the mouth, warm in nature, promoting blood flow to regulate menstruation, relaxing muscles and tendons and activating QI and blood in the collateral, for menoxenia, dysmenorrhea；

Cortex Moutan: bitter, pungent, is slightly cold, GUIXIN, liver, kidney channel, clearing away heat and cooling blood, and blood circulation promoting and blood stasis dispelling is used for Maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters wound Bitterly；

The Radix Angelicae Dahuricae: expelling wind and cold, sensible pain relieving, detumescence and apocenosis, dampness leukorrhagia stopping, profit blood vessels, expelling wind and cold, Eliminating dampness and dredging channels, modern medicine study confirms, the Radix Angelicae Dahuricae is to escherichia coli, dysentery bacterium, Bacillus proteus, wound Cold bacillus, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc. all have inhibitory action；

Herba Portulacae: cold in nature, sweet in the mouth acid, enter the heart, liver, spleen, large intestine channel, have that removing dampness is antipruritic, heat clearing away Detumescence, heat-clearing and toxic substances removing, diuretic dries, and dissipates blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, and stop blooding removing heat from blood Effect.Herba Portulacae has stronger inhibitory action to dysentery bacterium, Bacillus typhi and escherichia coli, can be used for The auxiliary treatment of various inflammation, have the title of " natural antibiotics ", and Herba Portulacae is also rich in vitamin C simultaneously, Vitamin C has good antioxidation can be with whitening nourishes rough skin, and modern medicine finds, Herba Portulacae There are higher nutritive value and medical value, except containing conventional proteins,vitamins,and minerals etc. Outside nutrient, Herba Portulacae is possibly together with unique bioactive ingredients, it is possible to strengthen Human Epithelial Cells Activity, help lend some impetus to ulcer and healing；

Herba Herminii: sweet in the mouth, warm in nature, kidney and spleen invigorating, regulating menstruation and activating blood, removing toxic substances, main dizzy insomnia, irritated Thirsty, anorexia, menoxenia, venom, Herba Herminii has low sugar, high protein and rich in many Kind of vitamin, aminoacid and the feature of trace element, the height of its selenium constituent content, China's Vegetable, In fruit variety, exception is the most rare；

Radix Glycyrrhizae Preparata: containing multiple chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, have anti- Inflammation and anti-allergy action, scalable body's immunity, antitumor and analgesic effect, therefore process sweet The primary efficacy of grass is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription；

Fructus Artocarpi Heterophylli: have quench the thirst, lactogenesis, invigorating the spleen and replenishing QI effect, local blood circulation can be improved, to gas Guan Yan, bronchial asthma, acute pneumonia, pharyngolaryngitis, retinitis, mastitis, engorgement of breasts in puerperal, The diseases such as postpartum thrombophlebitis, arthritis, periarthritis, cellulitis, ulcus cruris are equal Effective in cure, research finds that Fructus Artocarpi Heterophylli has antioxidation, antibacterial, antiinflammatory, adjunct antineoplastic, suppression melanin The modern medicinal efficacy such as generation and auxiliary hyperglycemic；

Eucalyptus globulus Labill: the micro-hardship pungent, micro-of taste, property is flat, and dispelling wind is antipyretic, inhibiting bacteria and diminishing inflammation, and anticorrosion is antipruritic, for pre- Anti-influenza, epidemic cerebrospinal meningitis, control upper respiratory tract infection, pharyngolaryngitis, bronchitis, Pneumonia, Acute and chronic pyelonephritis, enteritis, dysentery, filaricide, external controls burn and scald, cellulitis, Mastitis, furuncle and phyma, erysipelas, paddy-field dermatitis, skin eczema, tinea pedis, skin degerming.

The traditional Chinese medical science thinks the pathogenic factor of mastitis, how by wet nurse's nipple deformity, cave in, be difficult to suckling or breast Juice is difficult to be emptied manylyly and newbornly, causes galactostasis, loses breast accumulation pyogenesis；Additionally feelings age of sucking will internal injury Depression of liver-QI, the liver failing to maintain the normal flow of QI bar reaches, and makes milk discharge not smooth or eating and drinking without temperance, positive bright accumulated heat, causes meridians Blocking, pathogenic heat are pented up for pus；Also can infect evil poison due to nipple ulceration, enter inner heat-transformation, meat corruption becomes pus. For the pathogeny of bovine subclinical mastitis, the raw material that the feed additive of the present invention is used not only is sought Support abundant, can fully supplement needed for milch cow the nutrient substance such as vitamin, mineral, trace element, also There is the effect of anti-inflammation, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, milk cow recessive breast can well be prevented Scorching, it is ensured that milk products quality, improve milk yield, in raw material, Fructus Forsythiae, Entermorpha, mangosteen skin, the Radix Angelicae Dahuricae, horse Bitterroot, Eucalyptus globulus Labill, Radix polygoni divaricati, Semen Caesalpiniae Minacis, Radix Glycyrrhizae Preparata, Fructus Artocarpi Heterophylli sarcocarp can well play antibacterial The effect of antiinflammatory, effectively suppression are killed such as the mammitis of cow such as staphylococcus aureus, staphylococcus epidermidis Pathogenic bacterium, reduce the sickness rate of mammitis of cow, thus reduce the use of antibiotic, wherein, Garcinia mangostana In skin rich in tannic acid pathogenic bacterium such as staphylococcus aureus, staphylococcus epidermidis to mammitis of cow Etc. there being antibacterial action, biomembranous formation can be affected；Mangosteen skin and Fructus Forsythiae, Herba basellae rubrae, Entermorpha, clam Clam powder, Cortex Moutan, Herba Portulacae, Semen Caesalpiniae Minacis, Herba Herminii, Eucalyptus globulus Labill share, and can well remove milch cow Internal accumulated heat heresy poison, nurses one's health milch cow body thus prevents latent mammitis；Meanwhile, raw material mangosteen skin is also Rich in procyanidin, procyanidin can strengthen blood capillary, tremulous pulse and vein blood vessel, and it has detumescenceization The effect become silted up, the drag reduction of blood capillary and permeability improve, and make cell be easier to absorb nutrient and row Except refuse, procyanidin can be with water solublity in scavenger cell film and fat-soluble free radical, it is suppressed that release Some enzyme goes to injure the process of capillary wall, and procyanidin suppression produces the enzyme that histamine needs, and prevents raw Become histamine, thus dephlogistication, with Fructus Forsythiae, Pulvis concha Mactrae, Flos seu Radix Impatientis nolitangeris, Cortex Moutan, the Radix Angelicae Dahuricae, Semen Caesalpiniae Minacis, Herba Herminii, Fructus Artocarpi Heterophylli sarcocarp act on the effect that can play good blood circulation promoting and blood stasis dispelling, lactogenesis jointly, preventing and treating The generation of recessive mammitis of cow, increases milk yield；The comprehensive synergism of each raw material, can effectively prevent and treat milk Cattle latent mammitis, improves milk yield.Herba basellae rubrae, mangosteen skin, Entermorpha, Herba Portulacae also have diuresis row The effect of poison, can promote that drug residue composition and toxin are discharged by urine in Contents in Cows, it is ensured that it is produced The food safety of milk.

The invention have the benefit that provide a kind of feed additive preventing bovine subclinical mastitis and Its preparation method, this feed additive can improve milk yield, reduces the sickness rate of mammitis of cow, with Time fully supplement the vitamin needed for milch cow and trace element, be prevented effectively from the material such as antibiotic, hormone Use, it is to avoid the pollution of dairy products, it is ensured that the edible safety of dairy products.Specifically:

(1) for the pathogeny of bovine subclinical mastitis, what the feed additive of the present invention was used raises Feed additives is the most nutritious, can fully supplement vitamin, mineral, trace element needed for milch cow Deng nutrient substance, also there is the effect of anti-inflammation, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, can well be pre- Anti-bovine subclinical mastitis, it is ensured that milk products quality, improves milk yield, in raw material, Fructus Forsythiae, Entermorpha, mountain Bamboo skin, the Radix Angelicae Dahuricae, Herba Portulacae, Eucalyptus globulus Labill, Radix polygoni divaricati, Semen Caesalpiniae Minacis, Radix Glycyrrhizae Preparata, Fructus Artocarpi Heterophylli sarcocarp are permissible Well playing the effect of anti-inflammation, effectively suppression is killed such as staphylococcus aureus, epidermis Fructus Vitis viniferae ball The pathogenic bacterium of the mammitis of cow such as bacterium, reduce the sickness rate of mammitis of cow, thus reduce making of antibiotic With, wherein, in mangosteen skin rich in tannic acid to the pathogenic bacterium such as staphylococcus aureus of mammitis of cow, Staphylococcus epidermidiss etc. have antibacterial action, can affect biomembranous formation；Mangosteen skin and Fructus Forsythiae, Auricularia Dish, Entermorpha, Pulvis concha Mactrae, Cortex Moutan, Herba Portulacae, Semen Caesalpiniae Minacis, Herba Herminii, Eucalyptus globulus Labill share, can be very The good accumulated heat heresy removed in Contents in Cows poison, nurses one's health milch cow body thus prevents latent mammitis；Meanwhile, Raw material mangosteen skin is also rich in procyanidin, and procyanidin can strengthen blood capillary, tremulous pulse and vein blood vessel, It has effect that detumescenceization is become silted up, and the drag reduction of blood capillary and permeability improve, and makes cell be easier to inhale Adopt point and get rid of refuse, procyanidin can with water solublity in scavenger cell film and fat-soluble free radical, Inhibiting some enzyme of release to go to injure the process of capillary wall, procyanidin suppression produces what histamine needed Enzyme, prevents from generating histamine, thus dephlogistication, with Fructus Forsythiae, Pulvis concha Mactrae, Flos seu Radix Impatientis nolitangeris, Cortex Moutan, white The root of Dahurian angelica, Semen Caesalpiniae Minacis, Herba Herminii, Fructus Artocarpi Heterophylli sarcocarp jointly act on and can play good blood circulation promoting and blood stasis dispelling, lactogenesis Effect, the generation of the recessive mammitis of cow of preventing and treating, increase milk yield；The comprehensive synergism of each raw material, Can effectively prevent and treat bovine subclinical mastitis, improve milk yield.Herba basellae rubrae, mangosteen skin, Entermorpha, Herba Portulacae Also there is the effect of diuresis toxin expelling, can promote that drug residue composition and toxin are discharged by urine in Contents in Cows, Guarantee the food safety of its produced milk.

(2) mangosteen skin in the raw material chosen of the present invention, Herba basellae rubrae fresh goods, Entermorpha fresh goods, Pulvis concha Mactrae, Herba Portulacae fresh goods, Herba Herminii fresh goods, Fructus Artocarpi Heterophylli sarcocarp are rich in multivitamin, mineral, trace element With the nutrient substance needed for the milch cow health such as aminoacid, use vacuum lyophilization to obtain method and prepare this feedstuff Fully maintain in raw material easily by nutrient substance such as the procyanidin of high temperature, vitamin, in feedstuff Nutritional labeling can be that milch cow provides sufficient vitamin, trace element, it is not necessary to extra other vitamin of interpolation Additive and trace mineral supplement, can fully meet its nutritional need, improves milk crop.

(3) feed additive of the present invention is using fruit and vegerable and Chinese herbal medicine as raw material, with milk cow forage homology with Body, can play the effect of preventing and treating mammitis of cow, contributes to again growing and growing up, and milch cow easily absorbs, Easily getting rid of, ejection can be as the fertilizer of crops, will not be to environment, with rear without medicine Thing remains, nuisanceless to human body, has important economy and social value.

Detailed description of the invention

According to following embodiment, the present invention be may be better understood.But, those skilled in the art holds Readily understood, concrete material proportion, process conditions and result thereof described by embodiment are merely to illustrate this Invention and should be without limitation on the present invention described in detail in claims yet.

Embodiment 1

A kind of feed additive preventing bovine subclinical mastitis, makes the raw material group of described feed additive Become and parts by weight are: Fructus Forsythiae 9 parts, mangosteen skin 15 parts, Herba basellae rubrae fresh goods 30 parts, Entermorpha fresh goods 20 Part, Pulvis concha Mactrae 2 parts, Semen Caesalpiniae Minacis 6 parts, Radix polygoni divaricati 6 parts, Flos seu Radix Impatientis nolitangeris 4 parts, Cortex Moutan 3 parts, The Radix Angelicae Dahuricae 9 parts, Herba Portulacae fresh goods 15 parts；Herba Herminii fresh goods 10 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Artocarpi Heterophylli sarcocarp 8 Part, Eucalyptus globulus Labill 9 parts.

The preparation method of the feed additive of above-mentioned prevention bovine subclinical mastitis, comprises the following steps:

(1) Fructus Forsythiae, Semen Caesalpiniae Minacis, Radix polygoni divaricati, Flos seu Radix Impatientis nolitangeris, Cortex Moutan, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Eucalyptus globulus Labill Pulverizing to obtain 50 mesh mixed-powders, gained mixed-powder adds the water soaking 1 hour of gross mass multiple 5 times, Slow fire boiling 1 hour, crosses 500 mesh drainage screens and obtains filtrate, again add mixed-powder gross mass after decoction The water soaking that multiple is 5 times 0.5 hour, slow fire boiling is crossed 500 mesh drainage screens after 1 hour and is obtained filtrate, closes And twice gained filtrate is cooled to room temperature, standby；

(2) mangosteen skin, Herba basellae rubrae fresh goods, Entermorpha fresh goods, Herba Portulacae fresh goods, Herba Herminii fresh goods, Fructus Ananadis comosi Mamoncillo meat is cleaned, and adds step (1) gained filtrate and grinds pulping；

(3) step (2) gained slurry mixes with Pulvis concha Mactrae, carries out homogeneous in addition homogenizer, homogeneous Temperature 15 ± 2 DEG C, 13 ± 2 minutes time, obtains batch mixing；

(4) step (3) gained batch mixing is carried out vacuum lyophilization and obtain mixed-powder；

(5) to step (4) gained mixed-powder ultraviolet sterilization 25 ± 5 minutes, milch cow must be prevented hidden The feed additive of property mastitis.

Embodiment 2

A kind of feed additive preventing bovine subclinical mastitis, makes the raw material group of described feed additive Become and parts by weight are: Fructus Forsythiae 12 parts, mangosteen skin 30 parts, Herba basellae rubrae fresh goods 40 parts, Entermorpha fresh goods 30 Part, Pulvis concha Mactrae 4 parts, Semen Caesalpiniae Minacis 9 parts, Radix polygoni divaricati 9 parts, Flos seu Radix Impatientis nolitangeris 7 parts, Cortex Moutan 5 parts, The Radix Angelicae Dahuricae 12 parts, Herba Portulacae fresh goods 20 parts；Herba Herminii fresh goods 15 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Artocarpi Heterophylli sarcocarp 10 parts, Eucalyptus globulus Labill 12 parts.

The preparation method of the feed additive of embodiment 2 is same as in Example 1.

Embodiment 3

A kind of feed additive preventing bovine subclinical mastitis, makes the raw material group of described feed additive Become and parts by weight are: Fructus Forsythiae 11 parts, mangosteen skin 22 parts, Herba basellae rubrae fresh goods 35 parts, Entermorpha fresh goods 25 Part, Pulvis concha Mactrae 3 parts, Semen Caesalpiniae Minacis 7 parts, Radix polygoni divaricati 7 parts, Flos seu Radix Impatientis nolitangeris 5 parts, Cortex Moutan 4 parts, The Radix Angelicae Dahuricae 11 parts, Herba Portulacae fresh goods 17 parts；Herba Herminii fresh goods 17 parts, Radix Glycyrrhizae Preparata 6 parts, Fructus Artocarpi Heterophylli sarcocarp 9 parts, Eucalyptus globulus Labill 10 parts.

The preparation method of the feed additive of embodiment 3 is same as in Example 1.

Embodiment 4 feed additive is on milk yield and the impact of milk products quality

Select the holstein cow 100 that clinical health, lactation period are identical, be randomly divided into 1 matched group With three experimental grouies, often organize 25 cow heads, with roughage (Leymus chinensis (Trin.) Tzvel.) and the 30wt% concentrated feed of 70wt% Coordinating and raise 60, every day, every cow head was raised by 12 kg diet, the raw material of each group concentrated feed used Mass percent be:

Matched group: Semen Maydis 64.8%, soybean cake 33%, salt 1.2%, calcium phosphate 1%；

Experimental group A: Semen Maydis 61.6%, soybean cake 33%, salt 1.2%, calcium phosphate 1%, the feedstuff of embodiment 1 Additive 3.2%；

Experimental group B: Semen Maydis 61.6%, soybean cake 33%, salt 1.2%, calcium phosphate 1%, the feedstuff of embodiment 2 Additive 3.2%；

Experimental group 3: Semen Maydis 61.6%, soybean cake 33%, salt 1.2%, calcium phosphate 1%, the feedstuff of embodiment 3 Additive 3.2%.

Adding up the average daily milk yield of each group of milch cow, acquired results is as follows:

	Matched group	Experimental group A	Experimental group B	Experimental group C
					Average daily milk yield (kg)	27.8	29.5	31.2	30.4

As can be seen from the above results, the feed additive of the present invention can be effectively improved milk production of cow.

Respectively adopt milk sample once before experiment and at the end of experiment, take early, middle and late in 4: 3: 3 ratios Three aggregate samples of milking.On-the-spot adding preservative agent 1-2 drips, 4 DEG C of preservations.Milk composition automatic analyzer is used to survey Determine the conventional ingredients in milks such as butterfat percnetage (Fat), lactoprotein (Pro), lactose (Lac), milk dry matter (DM), Before and after gained experiment, each group milk conventional index statistical table is following (%):

The above results shows that the feed additive of the present invention can ensure the nutrient composition content in milk.

Embodiment 5 latent mammitis morbidity statistics (CMT method)

Before feeding and after feeding 60, each newborn district organizing milch cow in embodiment 4 is used CMT method inspection Mastitis sickness rate.CMT is a kind of method of indirect determination somatic number, be the most commonly used reliability relatively The high latent mammitis method of inspection.Its principle is: with surfactant alkyl base sulphur (sulfur) Hydrochlorate makes various leukocyte in milk expand degeneration, and caustic soda (NaOH) accelerates the change of cell electric charge. So, in the case of gap between leukocyte and electric charge thereof change, degenerating cell is each other There will be condensation.Thus judge Somatic Cells Content in milk by condensation degree approximation, and then understanding should The order of severity that the mastitis in breast district has that it's too late.Statistics milch cow CMT checks the ratio (subclinical mastitis that is positive Ill ratio) following (%):

	Before experiment	After experiment
			Matched group	40%	44%
Experimental group A	36%	20%
			Experimental group B	40%	16%
Experimental group C	44%	20%

By the above results it can be seen that the feed additive of the present invention, can effectively reduce recessive milk Lac Bovis seu Bubali The sickness rate that room is scorching, effectively prevents and treats mammitis of cow.

Embodiment of above only for technology design and the feature of the present invention are described, its object is to allow and is familiar with this The people of item technology understands present invention and is carried out, and can not limit the scope of the invention with this, All equivalence changes done according to spirit of the invention or modification, all should contain the protection model in the present invention In enclosing.

Claims (5)

1. the feed additive preventing bovine subclinical mastitis, it is characterised in that: make described feedstuff and add Add agent raw material composition and parts by weight be: Fructus Forsythiae 9-12 part, mangosteen skin 15-30 part, Herba basellae rubrae fresh goods 30-40 Part, Entermorpha fresh goods 20-30 part, Pulvis concha Mactrae 2-4 part, Semen Caesalpiniae Minacis 6-9 part, Radix polygoni divaricati 6-9 part, water Gold phoenix 4-7 part, Cortex Moutan 3-5 part, Radix Angelicae Dahuricae 9-12 part, Herba Portulacae fresh goods 15-20 part；Herba Herminii fresh goods 10-15 part, Radix Glycyrrhizae Preparata 5-8 part, Fructus Artocarpi Heterophylli sarcocarp 8-10 part, Eucalyptus globulus Labill 9-12 part.

A kind of feed additive preventing bovine subclinical mastitis the most as claimed in claim 1, its feature exists In: make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 9 parts, mangosteen skin 15 parts, Herba basellae rubrae fresh goods 30 parts, Entermorpha fresh goods 20 parts, Pulvis concha Mactrae 2 parts, Semen Caesalpiniae Minacis 6 parts, Radix polygoni divaricati 6 parts, Flos seu Radix Impatientis nolitangeris 4 parts, Cortex Moutan 3 parts, the Radix Angelicae Dahuricae 9 parts, Herba Portulacae fresh goods 15 parts；Herba Herminii fresh goods 10 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Artocarpi Heterophylli sarcocarp 8 parts, Eucalyptus globulus Labill 9 parts.

A kind of feed additive preventing bovine subclinical mastitis the most as claimed in claim 1, its feature exists In: make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 12 parts, mangosteen skin 30 parts, Herba basellae rubrae fresh goods 40 parts, Entermorpha fresh goods 30 parts, Pulvis concha Mactrae 4 parts, Semen Caesalpiniae Minacis 9 parts, Radix polygoni divaricati 9 parts, Flos seu Radix Impatientis nolitangeris 7 parts, Cortex Moutan 5 parts, the Radix Angelicae Dahuricae 12 parts, Herba Portulacae fresh goods 20 parts；Herba Herminii fresh goods 15 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Artocarpi Heterophylli sarcocarp 10 parts, Eucalyptus globulus Labill 12 parts.

A kind of feed additive preventing bovine subclinical mastitis the most as claimed in claim 1, its feature exists In: make described feed additive raw material composition and parts by weight be: Fructus Forsythiae 11 parts, mangosteen skin 22 parts, Herba basellae rubrae fresh goods 35 parts, Entermorpha fresh goods 25 parts, Pulvis concha Mactrae 3 parts, Semen Caesalpiniae Minacis 7 parts, Radix polygoni divaricati 7 parts, Flos seu Radix Impatientis nolitangeris 5 parts, Cortex Moutan 4 parts, the Radix Angelicae Dahuricae 11 parts, Herba Portulacae fresh goods 17 parts；Herba Herminii fresh goods 17 parts, Radix Glycyrrhizae Preparata 6 parts, Fructus Artocarpi Heterophylli sarcocarp 9 parts, Eucalyptus globulus Labill 10 parts.

5. the preparation of a kind of feed additive preventing bovine subclinical mastitis as described in Claims 1-4 Method, it is characterised in that comprise the following steps:

(1) Fructus Forsythiae, Semen Caesalpiniae Minacis, Radix polygoni divaricati, Flos seu Radix Impatientis nolitangeris, Cortex Moutan, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Eucalyptus globulus Labill powder The broken 50 mesh mixed-powders that obtain, the water soaking of gained mixed-powder addition gross mass multiple 5 times 1 hour, slow fire Decoct 1 hour, cross 500 mesh drainage screens after decoction and obtain filtrate, again add mixed-powder gross mass multiple 5 Water soaking again 0.5 hour, slow fire boiling is crossed 500 mesh drainage screens after 1 hour and is obtained filtrate, merges twice institute Obtain filtrate and be cooled to room temperature, standby；

(2) mangosteen skin, Herba basellae rubrae fresh goods, Entermorpha fresh goods, Herba Portulacae fresh goods, Herba Herminii fresh goods, Fructus Artocarpi Heterophylli Sarcocarp is cleaned, and adds step (1) gained filtrate and grinds pulping；

(3) step (2) gained slurry mixes with Pulvis concha Mactrae, carries out homogeneous, homogeneous temperature in addition homogenizer Spend 15 ± 2 DEG C, 13 ± 2 minutes time, obtain batch mixing；

(4) step (3) gained batch mixing is carried out vacuum lyophilization and obtain mixed-powder；

(5) to step (4) gained mixed-powder ultraviolet sterilization 25 ± 5 minutes, prevention milk cow recessive is obtained The feed additive of mastitis.