CN103300446A - Functional blueberry beverage composition - Google Patents

Functional blueberry beverage composition Download PDF

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Publication number
CN103300446A
CN103300446A CN2013101525106A CN201310152510A CN103300446A CN 103300446 A CN103300446 A CN 103300446A CN 2013101525106 A CN2013101525106 A CN 2013101525106A CN 201310152510 A CN201310152510 A CN 201310152510A CN 103300446 A CN103300446 A CN 103300446A
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blueberry
composition
schisandrae chinensis
solution
fructus lycii
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姜波
宋文婷
张华�
包永明
安利佳
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Dalian University of Technology
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Dalian University of Technology
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Abstract

The invention provides a functional blueberry beverage composition which consists of the following components in percentage by volume: 5-40 percent of blueberry juice, 1-20 percent of a medlar extracting solution, 0.5-5 percent of a fructus schizandrae extracting solution, and the balance of water. The blueberry juice is obtained by squeezing fresh blueberries. According to the blueberry functional beverage composition, by using a simple mixing technology, the effects such as oxygen deficit resistance, fatigue resistance, oxidization resistance, and tumor resistance of the blueberries, medlar and fructus schizandrae are enhanced with one another and are better than the pure sum of the effects of single-flavor components on respective aspects. Therefore, the composition is extremely good in mixing effect; animal experiment show that the obvious effects on resisting oxidization resistance, preventing fatigues, improving the immunity and clearing free radicals are achieved; the formula and the preparation technology are simple; the functional blueberry beverage composition is convenient to use and free of toxic and side effects.

Description

A kind of blueberry drinks composition
Background technology
Blueberry (blueberry) is Ericaceae (Ericaceae) Vaccinium (Vaccinium spp.) evergreen shrubs, it is a kind of huckleberry berry with higher economic worth that originates in North America, it is blue or black-and-blue so claim blueberry that its pericarp is, and now mostly is cultivation.The blueberry fruits nutrition is abundant, except containing conventional sugar, amino acid, dietary fiber, also be rich in trace elements such as vitamin E, vitamin A and Cobastab and iron, zinc, potassium, manganese, in addition its anthocyanidin that contains have anti-oxidant, eliminate visual fatigue, strengthen cardiac function, improve immunity, remove free radical, delay senility and multiple physiologically active such as anticancer.
The fruit of Chinese wolfberry is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Its flavor is sweet, property is flat has the effect of liver-kidney tonifying, say in the Compendium of Material Medica " obey hard muscles and bones for a long time, it is not old to make light of one's life by commiting suicide, cold-resistant heat ... mend the vital essence various symptims and signs of deficiency, easily color bleaches, and makes eye bright and calms the nerves, and makes us long-lived ".The traditional Chinese medical science commonly used it treat liver-kidney Yin deficiency, soreness and weakness of waist and knees, dizziness, forgetful, dizzy, many tears of blurred vision, quench one's thirst, illness such as seminal emission.Modern pharmacology studies confirm that the fruit of Chinese wolfberry can regulate body's immunity, can effectively suppress tumor growth and cell mutation, have delay senility, the effect of AFL, adjusting blood fat and aspects such as blood sugar, promotion hematopoiesis function, and be applied to clinical.
Fruit of Chinese magnoliavine Schisandra chinensis (Turcz) Ball. is the dry mature fruit of magnoliaceae schisandra, and Shennong's Herbal is classified as top grade, and " the sweet acid of five tastes skin and flesh is worked hard in the nuclear, and saline taste is arranged " carried in Tang " Tang materia medica ", so the name fruit of Chinese magnoliavine.Be the ripening fruits of magnoliaceae schisandra, practise title " fructus schisandrae "; Equal plant schisandra chinensis is practised and is claimed " kadsura longepedunculata ".Li Shizhen (1518-1593 A.D.) meaning: " five tastes the present has the southern product person of the branch in north and south look red, and northern product person look black, and going into tonic must be good with northern product person ".What usually says is " fructus schisandrae ", is famous nourishing Chinese medicine, has multiple efficacies, comprises anti-oxidant, anti-senility anti-fatigue etc.
The functional product of the blueberry of exploitation is many based on anthocyanidin at present.But research is less aspect the health care of blueberry compound, does not also see outstanding product.
Summary of the invention
The object of the invention is to provide a kind of blueberry drinks composition, and is composed of the following components according to percent by volume:
Wherein said blueberry juice is blueberry fresh fruit squeezing gained.
As preferably, described composition is made up of the water of blueberry juice 25~35%, fructus lycii extracted solution 5~15%, Fructus Schisandrae Chinensis extractive solution 1~2% and surplus according to percent by volume.The most preferably, described blueberry drinks composition is made up of the water of blueberry juice 30%, fructus lycii extracted solution 10%, Fructus Schisandrae Chinensis extractive solution 1% and surplus according to percent by volume.
Fructus lycii extracted solution described in the described blueberry drinks of the invention described above composition prepares by following method:
1. matrimony vine and 50% ethanol are pressed solid-liquid ratio 1g:20ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution I of getting;
2. filter residue and 50% ethanol are pressed solid-liquid ratio 1g:10ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution II of getting;
3. merge fructus lycii extracted solution I and fructus lycii extracted solution II is fructus lycii extracted solution.
Fructus Schisandrae Chinensis extractive solution described in the described blueberry drinks of the invention described above composition prepares by following method:
1. the fruit of Chinese magnoliavine and 70% ethanol are pressed solid-liquid ratio 1g:20ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution I of getting;
2. filter residue and 70% ethanol are pressed solid-liquid ratio 1g:10ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution II of getting
3. merge Fructus Schisandrae Chinensis extractive solution I and Fructus Schisandrae Chinensis extractive solution II is Fructus Schisandrae Chinensis extractive solution.
The most preferably, blueberry drinks composition of the present invention is made up of the water of 30% blueberry juice, 10% fructus lycii extracted solution, 1% Fructus Schisandrae Chinensis extractive solution and surplus.Wherein ratio all refers to according to percent by volume.
Blueberry drinks composition of the present invention is by simple complex process, blueberry, matrimony vine and the fruit of Chinese magnoliavine are strengthened mutually in the effect of anti-anoxic, antifatigue, each side such as anti-oxidant, antitumor, surpass single component effect in all fields add merely and.Therefore, above-mentioned composition of the present invention has shown very good composite effect, and zoopery shows, the effect of have anti-oxidant, antifatigue significantly, raising immunity, removing free radical, and prescription and preparation technology are simple, and be easy to use, do not see toxic and side effect.
The specific embodiment
Following embodiment is example with the described blueberry drinks of highly preferred technical scheme of the present invention composition.
Embodiment 1
Blueberry drinks preparation of compositions method:
Blueberry uses commercially available blueberry fresh fruit; Matrimony vine and the fruit of Chinese magnoliavine are used commercially available medicinal material.
1, preparation blueberry juice: the blueberry fresh fruit press juice, with the vivid blue certain kind of berries of 10g: the yield ratio control squeezing degree of 7mL blueberry juice.
2, preparation fructus lycii extracted solution:
1. matrimony vine and 50% ethanol are pressed solid-liquid ratio 1g:20ml mixing soaked overnight (about 12h), and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution I of getting;
2. filter residue and 50% ethanol are pressed solid-liquid ratio 1g:10ml mixing soaked overnight (about 12h), and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution II of getting;
3. merge fructus lycii extracted solution I and fructus lycii extracted solution II is fructus lycii extracted solution.
3, preparation Fructus Schisandrae Chinensis extractive solution:
1. the fruit of Chinese magnoliavine and 70% ethanol are pressed solid-liquid ratio 1g:20ml mixing soaked overnight (about 12h), and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution I of getting;
2. filter residue and 70% ethanol are pressed solid-liquid ratio 1g:10ml mixing soaked overnight (about 12h), and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution II of getting
3. merge Fructus Schisandrae Chinensis extractive solution I and Fructus Schisandrae Chinensis extractive solution II is Fructus Schisandrae Chinensis extractive solution.
4, composition is composite: according to volume parts, 1 part of 10 parts of 30 parts in blueberry juice, fructus lycii extracted solutions, Fructus Schisandrae Chinensis extractive solution and 59 parts of fully mixing of water with above-mentioned preparation namely get blueberry drinks composition.
Embodiment 2
The anti-anoxic effect experiment of blueberry drinks composition (embodiment 1 makes):
(1) experimental technique
80 of kunming mices, male and female half and half are divided into 4 groups at random, 20 every group, are made as negative control group, positive controls, low dosage test group and high dose test group respectively.
Environmental condition unanimity of living in is organized in all tests, 25 ± 1 ℃ of temperature, relative humidity 70%, natural lighting, mouse freely ingest (standard feed, GB14924.3-2001) and drinking-water, gastric infusion, the administration condition is:
Negative control group: physiological saline 20ml/kg;
Positive controls: commercially available red drink heavily material 20ml/kg;
The blueberry drinks composition 20ml/kg that high dose test group: embodiment 1 is prepared;
The blueberry drinks composition 10ml/kg that low dosage test group: embodiment 1 is prepared.
(2) detect hypoxia endurance time: every group of mouse got 10 at random, and fasting is 4 hours after administration in the 14th day, and every group of mouse placed the airtight wide-mouth bottle of 250ml that soda lime 15 grams are housed respectively, and the vaseline sealing is observed mouse and ceased breathing the time.The results are shown in following table 1:
Table 1 blueberry composition to the influence of anti-anoxic time-to-live of mouse normal pressure (X ± SD, n=10)
Figure BDA00003118133600031
Figure BDA00003118133600041
Annotate: compare * * P<0.01 with negative control group, compare with positive controls P<0.05
From the result of table 1 as seen: blueberry drinks composition high and low dose group of the present invention all can effectively prolong the mouse normal pressure anti-anoxic time-to-live.Compare with positive control, have statistical significance.
(3) detect biochemical indicator: the fasting 4 hours after administration in the 14th day of every group of remaining mouse, every group of mouse placed the airtight wide-mouth bottle of 250ml that soda lime 15 grams are housed respectively, the vaseline sealing is plucked eyeball after 10 minutes and is got blood, measures blood-sugar content; Centrifuging and taking serum is pressed the kit specification and is measured mouse blood lactic acid content, serum urea nitrogen content.The result is as shown in table 2.
Table 2 blueberry composition to the anti-anoxic of mouse normal pressure after biochemical indicator influence (X ± SD, n=10)
Figure BDA00003118133600042
Annotate: compare * P<0.05 with negative control group, compare with positive controls * * P<0.01 P<0.05, △ △P<0.01
From the testing result of table 2 as seen: compare with negative control group, blueberry drinks composition high and low dose group of the present invention all can reduce blood lactic acid after the anti-anoxic of mouse normal pressure, serum urea nitrogen and blood sugar effectively, and statistical significance (P<0.01) is arranged; With positive control relatively, high dose and low dose group can reduce blood lactic acid and blood sugar (P<0.05) after the anti-anoxic of mouse normal pressure, high dose can reduce mice serum urea nitrogen (P<0.01).
Embodiment 3
The antifatigue measure of merit of blueberry drinks composition (embodiment 1 makes)
1, the influence of mouse grip is tested
(1) experimental technique:
60 of kunming mices, male and female half and half, be divided into 6 groups at random, 10 every group, be respectively negative control group, positive controls, composition test group, blueberry juice test group, fructus lycii extracted solution test group, Fructus Schisandrae Chinensis extractive solution test group, each organizes the environmental condition unanimity, 25 ± 1 ℃ of temperature, relative humidity 70%, natural lighting, mouse freely ingest (standard feed, GB14924.3-2001) and drinking-water.Gastric infusion, the administration condition is:
Negative control group: physiological saline 20ml/kg;
Positive controls: commercially available red drink heavily material 20ml/kg;
The blueberry drinks composition 10ml/kg that composition test group: embodiment 1 is prepared;
Blueberry juice test group: the blueberry juice 10ml/kg that embodiment 1 step 1 is prepared;
Fructus lycii extracted solution test group: the fructus lycii extracted solution 10ml/kg that embodiment 1 step 2 is prepared;
Fructus Schisandrae Chinensis extractive solution test group: the Fructus Schisandrae Chinensis extractive solution 10ml/kg that embodiment 1 step 3 is prepared
3d before the administration, be placed on 2 little fore paws on the cord of the high 0.5m in ground, long 1.2m and train mouse every day.After the drug withdrawal the 24th hour, mouse is placed on the cord, record its power and exhaust the time of landing.
(2) experimental result, testing result is as shown in table 3:
Table 3 blueberry composition to the effect of mouse grip (X ± SD, n=10)
Annotate: compare * * P<0.01 with negative control group, compare with positive controls △ △P<0.01, P<0.05.
From the testing result of table 3 as seen: blueberry composition group of the present invention all can effectively prolong mouse lands the time, compares with negative control group, positive control and each single component, all has statistical significance.
2, mouse power is exhausted the influence of swimming time
(1) experimental technique:
60 of kunming mices, male and female half and half, be divided into 6 groups at random, 10 every group, be respectively negative control group, positive controls, blueberry composition test group, blueberry juice test group, fructus lycii extracted solution test group, Fructus Schisandrae Chinensis extractive solution test group, each organizes the environmental condition unanimity, 25 ± 1 ℃ of temperature, relative humidity 70%, natural lighting, mouse freely ingest (standard feed, GB14924.3-2001) and drinking-water.Gastric infusion, the administration condition is:
Negative control group: physiological saline 20ml/kg;
Positive controls: commercially available red drink heavily material 20ml/kg;
The blueberry drinks composition 10ml/kg that composition test group: embodiment 1 is prepared;
Blueberry juice test group: the blueberry juice 10ml/kg that embodiment 1 step 1 is prepared;
Fructus lycii extracted solution test group: the fructus lycii extracted solution 10ml/kg that embodiment 1 step 2 is prepared;
Fructus Schisandrae Chinensis extractive solution test group: the Fructus Schisandrae Chinensis extractive solution 10ml/kg that embodiment 1 step 3 is prepared
After 1 hour, be the sheet lead of its body weight 10% at afterbody at the 14th day mouse last gastric infusion, put into diameter 120cm, in the water tank of height 40cm, sink to all with mouse head that to continue can not emerge in 10 seconds be that power exhausts swimming time.
(2) experimental result, as table 4:
Table 4 composition to mouse power exhaust swimming time influence (X ± SD, n=10)
Figure BDA00003118133600061
Annotate: compare * * P<0.01 with negative control group, compare with positive controls △ △P<0.01
From table 4 result as seen: blueberry composition test group of the present invention can effectively prolong the mouse swimming time, compares with negative control group, positive control and each single component, all has statistical significance.
Embodiment 4
The antioxidant effect test of blueberry drinks composition (embodiment 1 makes)
(1) experimental technique:
Take out 15 days kunming mice embryo of gestational age under the sterile working, isolate the both sides cerebral cortex, machinery is blown and beaten with the fragmentation tissue in DMEM/F12 then.Cell suspension 10min after the 1000r centrifugal machine separates removes the histocyte fragment.Abandon supernatant, count the cell after resuspended and be inoculated into poly-D-lysine (20 μ g/ml) and wrap in advance in 24 well culture plates of quilt, the cell inoculum density is 1 * 10 5/ hole.This research selects for use DMEM/F12 to add 10% inactivated fetal bovine serum, 100U/ml penicillin, and the 100U/ml streptomysin is as cell culture fluid.Cell was cultivated after 48 hours, added 10 μ M β-arabinose furanosides (β-D-arabinofuranoside) breed to suppress spongiocyte.After 48 hours, displace old nutrient solution with fresh cell culture fluid.Cultivate the 7th day, cell was used for experiment (pure neuron cultivating system deutocerebrum cortical neuron purity 〉=95%).Add different samples respectively in culture medium, each concentration is established 6 holes, detects endogenous polyphenoils glutathione peroxidase (GSH-PX), content or the activity of superoxide dismutase (SOD) and glutathione (GSH) behind the cultivation 48h.Concrete every group of cell administration condition is as follows:
Negative control group: physiological saline 50 μ l/ holes;
Positive controls: commercially available red drink heavily material 50 μ l/ holes;
The blueberry drinks composition 50 μ l/ holes that composition test group: embodiment 1 is prepared;
Blueberry juice test group: the blueberry juice 50 μ l/ holes that embodiment 1 step 1 is prepared;
Fructus lycii extracted solution test group: the fructus lycii extracted solution 50 μ l/ holes that embodiment 1 step 2 is prepared;
Fructus Schisandrae Chinensis extractive solution test group: the Fructus Schisandrae Chinensis extractive solution 50 μ l/ holes that embodiment 1 step 3 is prepared
(2) experimental result:
Blueberry drinks composition sees Table 5 to the antioxidant effect of mouse nerve cell.
Table 5 composition is to the influence of the antioxidation of mouse nerve cell
Figure BDA00003118133600071
Annotate: compare * P<0.05 with negative control group, compare with positive controls * * P<0.01 △ △P<0.01
From the result of table 5 as seen: compare with positive controls, the composition GSH-PX that can raise, SOD and GSH, effect is (P<0.01) extremely significantly; Blueberry juice has statistical significance (P<0.05) to the action effect of GSH-PX and GSH; The no obvious antioxidant effect of other each groups.
Embodiment 5
The antitumous effect experiment of blueberry composition
(1) experimental technique:
With the inhibiting rate of mtt assay test sample to tumour cell: cell is with 1 * 10 5The concentration of individual/ml is inoculated in 24 orifice plates, and every hole 1000 μ l add different samples respectively in culture medium behind the cultivation 24h, and every kind of sample adds 50 μ l, and test sample is to the inhibiting rate of following 4 kinds of growth of tumour cell behind the cultivation 48h.Adopt the MTT colorimetric method to detect.MTT is a kind of tetramethyl azo azoles salt, after being taken in by living cells, forms bluish violet crystallization first a ceremonial jade-ladle, used in libation in cell.The first a ceremonial jade-ladle, used in libation dissolves with DMSO, carries out colorimetric at ELIASA, the power of the big I reflection cell metabolic activity of the OD value that detects.To add 10 μ l MTT(final concentrations be 0.5mg/ml in every hole during detection) in 5%CO 2, cultivate 3h in 37 ℃ of incubators.Nutrient solution is removed in suction, and every Kong Zhongzai adds 100 μ l dimethyl sulfoxide (DMSO)s (DMSO) dissolving bluish violet crystal, and the thing to be crystallized that vibrates fully dissolves the back measures 570nm with ELIASA, and reference wavelength is the OD value of 630nm, the inhibiting rate of calculation sample cell growth.Concrete every group of cell administration condition is as follows:
Negative control group: physiological saline 50 μ l/ holes;
Positive controls: commercially available red drink heavily material 50 μ l/ holes;
The blueberry drinks composition 50 μ l/ holes that composition test group: embodiment 1 is prepared;
Blueberry juice test group: the blueberry juice 50 μ l/ holes that embodiment 1 step 1 is prepared;
Fructus lycii extracted solution test group: the fructus lycii extracted solution 50 μ l/ holes that embodiment 1 step 2 is prepared;
Fructus Schisandrae Chinensis extractive solution test group: the Fructus Schisandrae Chinensis extractive solution 50 μ l/ holes that embodiment 1 step 3 is prepared.
Inhibiting rate=(OD Blank-OD Dosing)/OD Blank* 100%
Table 6 composition is to the inhibiting rate % of tumour cell
Figure BDA00003118133600081
Annotate: compare * P<0.05 with negative control group, compare with positive controls * * P<0.01 △ △P<0.01, P<0.05
From the result of table 6 as can be seen, positive controls does not have obvious antitumous effect, and different test sample and tumor cell culture be after 48 hours, and the growth of tumour cell is had different inhibitions.Wherein, composition is to the NCI-H446(human small cell lung carcinoma), SMMC-7721(people's liver cancer), MCF-7(breast cancer) and BGC-823(people's cancer of the stomach) tangible antitumor activity effect is all arranged, and medlar extract liquid does not have obvious active function to three kinds of cells; Blueberry juice and Fructus Schisandrae Chinensis extractive solution have 15.0% and 12.2% inhibiting rate to the SMMC-7721 cell, and other tumour cells are not had obvious inhibitory action.

Claims (5)

1. blueberry drinks composition, composed of the following components according to percent by volume:
Figure FDA00003118133500011
Wherein said blueberry juice is blueberry fresh fruit squeezing gained.
2. the described blueberry drinks of claim 1 composition is characterized in that described composition is made up of the water of blueberry juice 25~35%, fructus lycii extracted solution 5~15%, Fructus Schisandrae Chinensis extractive solution 1~2% and surplus according to percent by volume.
3. the described blueberry drinks of claim 2 composition is characterized in that, is made up of the water of blueberry juice 30%, fructus lycii extracted solution 10%, Fructus Schisandrae Chinensis extractive solution 1% and surplus according to percent by volume.
4. claim 1,2 or 3 described blueberry drinks compositions is characterized in that described fructus lycii extracted solution prepares by following method:
1. matrimony vine and 50% ethanol are pressed solid-liquid ratio 1g:20ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution I of getting;
2. filter residue and 50% ethanol are pressed solid-liquid ratio 1g:10ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure fructus lycii extracted solution II of getting;
3. merge fructus lycii extracted solution I and fructus lycii extracted solution II is fructus lycii extracted solution.
5. claim 1,2 or 3 described blueberry drinks compositions is characterized in that described Fructus Schisandrae Chinensis extractive solution prepares by following method:
1. the fruit of Chinese magnoliavine and 70% ethanol are pressed solid-liquid ratio 1g:20ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution I of getting;
2. filter residue and 70% ethanol are pressed solid-liquid ratio 1g:10ml mixing immersion 8~24h, and behind the suction filtration, filtrate is revolved and steamed except the pure Fructus Schisandrae Chinensis extractive solution II of getting
3. merge Fructus Schisandrae Chinensis extractive solution I and Fructus Schisandrae Chinensis extractive solution II is Fructus Schisandrae Chinensis extractive solution.
CN2013101525106A 2013-04-27 2013-04-27 Functional blueberry beverage composition Pending CN103300446A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104643219A (en) * 2015-03-05 2015-05-27 临沂大学 Health blueberry and bitter gourd composite fruit juice beverage and preparation method thereof
CN105707591A (en) * 2014-12-05 2016-06-29 钟虹光 Blueberry and Chinese wolfberry fruit beverage having effect of improving eyesight
CN105918714A (en) * 2016-04-08 2016-09-07 沈阳农业大学 Blueberry-black wolfberry pulp juice and manufacturing method thereof
CN107048377A (en) * 2017-06-20 2017-08-18 哈尔滨工业大学 Spacefarer flies antifatigue chewable tablets and preparation method thereof for a long time
CN107303004A (en) * 2016-04-19 2017-10-31 东北农业大学 A kind of preparation method of anti-oxidation health beverage
CN108740617A (en) * 2018-06-09 2018-11-06 河南九术医药科技有限公司 A kind of health beverages improving immunity
CN109170888A (en) * 2018-09-18 2019-01-11 广东时代食品与生命健康研究有限公司 A kind of anti-oxidant, anti-Fatigue Composition and preparation method thereof
CN109663021A (en) * 2019-03-05 2019-04-23 通化禾韵现代农业股份有限公司 Composition, preparation method and application with anti-oxidation function
CN111557400A (en) * 2020-05-20 2020-08-21 吉林省自然蓝现代农业科技有限公司 Preparation method of blueberry composite beverage

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Publication number Priority date Publication date Assignee Title
CN1410006A (en) * 2002-09-09 2003-04-16 王惠忠 Wild schisandra chinensis wolfberry juice
CN101496605A (en) * 2009-03-02 2009-08-05 昆明添宝生物技术开发有限公司 Blueberry oral liquid
CN102389135A (en) * 2011-11-08 2012-03-28 杭州秀山美地农业科技有限公司 Anthocyanidin beverage formula and its production technology

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1410006A (en) * 2002-09-09 2003-04-16 王惠忠 Wild schisandra chinensis wolfberry juice
CN101496605A (en) * 2009-03-02 2009-08-05 昆明添宝生物技术开发有限公司 Blueberry oral liquid
CN102389135A (en) * 2011-11-08 2012-03-28 杭州秀山美地农业科技有限公司 Anthocyanidin beverage formula and its production technology

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105707591A (en) * 2014-12-05 2016-06-29 钟虹光 Blueberry and Chinese wolfberry fruit beverage having effect of improving eyesight
CN104643219A (en) * 2015-03-05 2015-05-27 临沂大学 Health blueberry and bitter gourd composite fruit juice beverage and preparation method thereof
CN105918714A (en) * 2016-04-08 2016-09-07 沈阳农业大学 Blueberry-black wolfberry pulp juice and manufacturing method thereof
CN107303004A (en) * 2016-04-19 2017-10-31 东北农业大学 A kind of preparation method of anti-oxidation health beverage
CN107048377A (en) * 2017-06-20 2017-08-18 哈尔滨工业大学 Spacefarer flies antifatigue chewable tablets and preparation method thereof for a long time
CN108740617A (en) * 2018-06-09 2018-11-06 河南九术医药科技有限公司 A kind of health beverages improving immunity
CN109170888A (en) * 2018-09-18 2019-01-11 广东时代食品与生命健康研究有限公司 A kind of anti-oxidant, anti-Fatigue Composition and preparation method thereof
CN109663021A (en) * 2019-03-05 2019-04-23 通化禾韵现代农业股份有限公司 Composition, preparation method and application with anti-oxidation function
CN109663021B (en) * 2019-03-05 2021-08-10 通化禾韵现代农业股份有限公司 Composition with antioxidant function, preparation method and application
CN111557400A (en) * 2020-05-20 2020-08-21 吉林省自然蓝现代农业科技有限公司 Preparation method of blueberry composite beverage

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Application publication date: 20130918