CN103298927B - 使结缔组织的损伤和毛病加速痊愈的方法 - Google Patents

使结缔组织的损伤和毛病加速痊愈的方法 Download PDF

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CN103298927B
CN103298927B CN201280004911.0A CN201280004911A CN103298927B CN 103298927 B CN103298927 B CN 103298927B CN 201280004911 A CN201280004911 A CN 201280004911A CN 103298927 B CN103298927 B CN 103298927B
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CN103298927A (zh
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G·L·辛
D·L·斯蒂德
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Stemnion LLC
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
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    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
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    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/27—Endoribonucleases producing 3'-phosphomonoesters (3.1.27)

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  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Cell Biology (AREA)
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  • Biotechnology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN201280004911.0A 2011-01-10 2012-01-07 使结缔组织的损伤和毛病加速痊愈的方法 Active CN103298927B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161460913P 2011-01-10 2011-01-10
US61/460,913 2011-01-10
PCT/US2012/000017 WO2012096796A1 (en) 2011-01-10 2012-01-07 Methods for accelerating the healing of connective tissue injuries and disorders

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CN103298927A CN103298927A (zh) 2013-09-11
CN103298927B true CN103298927B (zh) 2016-03-09

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US (3) US8642547B2 (enExample)
EP (1) EP2663637B1 (enExample)
JP (1) JP6041812B2 (enExample)
CN (1) CN103298927B (enExample)
CA (1) CA2823689C (enExample)
ES (1) ES2646438T3 (enExample)
WO (1) WO2012096796A1 (enExample)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
WO2015171880A1 (en) * 2014-05-08 2015-11-12 The University Of Florida Research Foundation, Inc. Sustained release angiogenesis modulating compositions and methods for induction and modulation of angiogenesis
WO2018123628A1 (ja) * 2016-12-28 2018-07-05 ロート製薬株式会社 細胞医薬組成物、疾患治療用キット及び細胞懸濁用溶液
BR112022000502A2 (pt) * 2019-08-09 2022-03-15 Axolotl Biologix Inc Método para preparar uma composição derivada de âmnion humano acelular configurada para uso terapêutico, método para tratar um sujeito sofrendo de doença articular degenerativa, e composição derivada de âmnion humano

Citations (1)

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WO2008088738A2 (en) * 2007-01-17 2008-07-24 Stemnion, Inc. Novel methods for modulating inflammatory and/or immune responses

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GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
DE69714035T2 (de) * 1997-08-14 2003-03-06 Sulzer Innotec Ag, Winterthur Zusammensetzung und Vorrichtung zur Reparatur von Knorpelgewebe in vivo bestehend aus Nanokapseln mit osteoinduktiven und/oder chondroinduktiven Faktoren
AU2002251935B2 (en) * 2001-02-14 2007-11-29 Celularity Inc. Post-partum mammalian placenta, its use and placental stem cells therefrom
GB0113697D0 (en) * 2001-06-06 2001-07-25 Smith & Nephew Fixation devices for tissue repair
US7473816B2 (en) * 2004-05-18 2009-01-06 Lohmann & Rauscher, Inc. Multilayer moisture management fabric
US20060222634A1 (en) 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof
US8153430B2 (en) 2005-03-31 2012-04-10 Stemnion, Inc. Methods related to surgery
US8241902B2 (en) 2006-01-11 2012-08-14 Technion Research & Development Foundation Ltd. Preparation of adult stem cell-derived connective tissue progenitors
US8871198B2 (en) * 2006-03-29 2014-10-28 Stemnion, Inc. Methods related to wound healing
US8475788B2 (en) * 2006-06-14 2013-07-02 Stemnion, Inc. Methods of treating spinal cord injury and minimizing scarring
JPWO2008102568A1 (ja) * 2007-02-22 2010-05-27 株式会社Ｐｇリサーチ 骨軟骨形成促進剤
EP2139497B1 (en) * 2007-04-13 2013-11-06 Stemnion, INC. Methods for treating nervous system injury and disease
US20080279825A1 (en) * 2007-05-10 2008-11-13 Malinin Theodore I Cartilage material
JP2010536851A (ja) 2007-08-22 2010-12-02 ステムニオン，インコーポレイテッド 新規の細胞性因子含有溶液組成物
WO2010012025A1 (en) * 2008-07-28 2010-02-04 Monash University Amnion epithelial cells for the treatment of degenerative disc disease
US20100215731A1 (en) * 2009-02-20 2010-08-26 Maastricht University Method for improving cartilage repair and/or preventing cartilage degeneration in a joint

Patent Citations (1)

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WO2008088738A2 (en) * 2007-01-17 2008-07-24 Stemnion, Inc. Novel methods for modulating inflammatory and/or immune responses

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US8883136B2 (en) 2014-11-11
ES2646438T3 (es) 2017-12-13
US20130183285A1 (en) 2013-07-18
CA2823689A1 (en) 2012-07-19
JP2014501778A (ja) 2014-01-23
WO2012096796A1 (en) 2012-07-19
JP6041812B2 (ja) 2016-12-14
US8642547B2 (en) 2014-02-04
US20160114008A1 (en) 2016-04-28
US20120177633A1 (en) 2012-07-12
CA2823689C (en) 2019-10-08
EP2663637A4 (en) 2014-08-06
CN103298927A (zh) 2013-09-11
EP2663637A1 (en) 2013-11-20
US9623089B2 (en) 2017-04-18
EP2663637B1 (en) 2017-09-27

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