CN103285034B - Medicine for treating chilblain and manufacturing method thereof - Google Patents
Medicine for treating chilblain and manufacturing method thereof Download PDFInfo
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- CN103285034B CN103285034B CN201310267521.9A CN201310267521A CN103285034B CN 103285034 B CN103285034 B CN 103285034B CN 201310267521 A CN201310267521 A CN 201310267521A CN 103285034 B CN103285034 B CN 103285034B
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- 208000010445 Chilblains Diseases 0.000 title claims abstract description 57
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 6
- 229940079593 drug Drugs 0.000 title 1
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims abstract description 87
- 239000000843 powder Substances 0.000 claims abstract description 68
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 63
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims abstract description 42
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- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 21
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims abstract description 21
- 239000005770 Eugenol Substances 0.000 claims abstract description 21
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229960002217 eugenol Drugs 0.000 claims abstract description 21
- 229960001047 methyl salicylate Drugs 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 21
- 229940099259 vaseline Drugs 0.000 claims abstract description 21
- 241001494479 Pecora Species 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 32
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 25
- 241000283898 Ovis Species 0.000 claims description 25
- 229910052799 carbon Inorganic materials 0.000 claims description 25
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 20
- 239000007766 cera flava Substances 0.000 claims description 20
- 229910052740 iodine Inorganic materials 0.000 claims description 20
- 239000011630 iodine Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 16
- 238000000227 grinding Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 13
- 238000009833 condensation Methods 0.000 claims description 8
- 230000005494 condensation Effects 0.000 claims description 8
- 238000001816 cooling Methods 0.000 claims description 8
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- 241000775848 Syringa oblata Species 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 239000004166 Lanolin Substances 0.000 abstract 1
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- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 235000019388 lanolin Nutrition 0.000 abstract 1
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- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 1
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Abstract
The invention belongs to the technical field of medicine chemical engineering, and particularly relates to a medicine for treating chilblain, which is characterized by comprising the following raw materials in parts by weight: 3-5 parts of iodine, 3-5 parts of potassium iodide, 8-12 parts of glycerol, 4-6 parts of lanolin, 4-8 parts of beeswax, 50-70 parts of vaseline, 1.5-5.5 parts of borneol, 0.5-1.5 parts of eugenol, 4-6 parts of methyl salicylate and 1-3 parts of sheep horn powder or ox horn powder or buckhorn powder with the fineness of less than 150 meshes. The invention also discloses a manufacturing method of the medicine for treating chilblain. The invention mainly has the advantages of simple manufacturing process, long storage time, short treatment time and low treatment cost, and is fragrant.
Description
Technical field
The invention belongs to pharmaceutical chemistry technical field, especially relate to a kind of medicine for the treatment of chilblain and preparation method thereof.
Background technology
Chilblain is more common in the low and humid region comparatively of winter temperature: be apt to occur in hands, foot, auricle and nose etc. and locate.Mainly repeatedly be exposed to low temperature environment and protect poor relevant with disease damage position.Finding expression in part has skin purple red color spot, pimple or the nodular lesion of gargalesthesia or distending pain, can accompany edema and water cellulitis.Course of disease mesocuticle is tear-away, hemorrhage, rotten to the corn or occur ulcer finally forming paralysed trace or fibrosis.Chilblain easily recurs, and reduces relevant with chronic vasculitis inflammatory and the skin resistance of ill rear local skin.The medicine of existing treatment chilblain is few and therapeutic effect is good not, and treatment time is long, and medical expense is high, uses inconvenient.
The domestic research for chilblain medicine has for many years and has a large amount of achievements in research, as the patent No. is: 200710168576.9, denomination of invention is: a kind of medicine for external use of anti-treating chilblain; As profit number is: 201110265936.3, denomination of invention is: snake oil liniment for preventing chilblain; And for example the patent No. is: 200810123744.7, denomination of invention is: a kind of medicine for the treatment of chilblain; For another example profit number is: 201210013689.2, denomination of invention is: a kind of Chinese medicine for the treatment of chilblain; Etc. patent of invention, all studied the medicine for the treatment of chilblain, but effect is all undesirable, for this reason, society urgently have treatment speed faster medicine occur.
Summary of the invention
For addressing the above problem, the object of the invention is to disclose a kind of medicine for the treatment of chilblain, it has treatment short treating period, the low texts of medical expense; Further, the present invention also discloses its manufacture method, and the present invention realizes by the following technical solutions.
A kind of medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
In first embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts.
In second embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part.
In the 3rd embodiment of the present invention, a kind of medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts.
The medicine for the treatment of chilblain described above, wherein said Cornu Caprae seu Ovis powder is the powder that the angle of goat or sheep or Saigae Tataricae is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
The medicine of above-mentioned treatment chilblain, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
The medicine of above-mentioned treatment chilblain, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
The medicine of above-mentioned treatment chilblain, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
Using method of the present invention: the present invention is coated in to chilblain position, and every 12～13 hours once, and at least continuous coating is 8 times, for rotten position, must not contact tap water during coating.
The present invention have make simple, long shelf-life, the advantage such as treatment time is short, medicine of the present invention has fragrance, during patient applies without uncomfortable sensation and untoward reaction; The present invention has long-time drug effect retention, applies number of times still less, and patient cures more convenient and quick.
Therefore, the present invention has following main beneficial effect: make simple, long shelf-life, treatment time is short, have fragrance, treatment cost is low.
The specific embodiment
embodiment 1
A kind of medicine for the treatment of chilblain, by weight, it includes following raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts; The medicine of described treatment chilblain, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: for 160 patients, test, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; In each age bracket, men and women half and half.According to < < combination of Chinese and Western medicine dermatological > > the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314), judge chilblain.In each age bracket, have half to fester, and the number men and women of festering equate; Through clinical use, apply after 10 times the whole rehabilitations of personnel of not festering; Apply after 16 times, in the people of festering, have 80% rehabilitation; Apply after 20 times all rehabilitations; Therefore, the present embodiment has good therapeutic effect.
embodiment 2
A kind of medicine for the treatment of chilblain, by weight, it includes following raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part; The medicine of described treatment chilblain, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: for 160 patients, test, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; In each age bracket, men and women half and half.According to < < combination of Chinese and Western medicine dermatological > > the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314), judge chilblain.In each age bracket, have half to fester, and the number men and women of festering equate; Through clinical use, apply after 12 times the whole rehabilitations of personnel of not festering; Apply after 16 times, in the people of festering, have 70% rehabilitation; Apply after 22 times all rehabilitations; Therefore, the present embodiment has good therapeutic effect.
embodiment 3
A kind of medicine for the treatment of chilblain, by weight, it includes following raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts; The medicine of described treatment chilblain, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
This embodiment is by following clinical trial: for 160 patients, test, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; In each age bracket, men and women half and half.According to < < combination of Chinese and Western medicine dermatological > > the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314), judge chilblain.In each age bracket, have half to fester, and the number men and women of festering equate; Through clinical use, apply after 8 times the whole rehabilitations of personnel of not festering; Apply after 14 times, in the people of festering, have 90% rehabilitation; Apply after 18 times all rehabilitations; Therefore, the present embodiment has good therapeutic effect.
The medicine of the treatment chilblain described in above-mentioned arbitrary embodiment, wherein said Cornu Caprae seu Ovis powder is the powder that the angle of goat or sheep or Saigae Tataricae is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
Repetition test through applicant, and clinical practice, find to adopt the medicine of following formula, can reach the application's object: a kind of medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
Above-mentioned formula is by following clinical trial: for 160 patients, test, age be 1-9 year be 20 people, age be 10-19 year be 20 people, age be 20-29 year be 20 people, age be 30-39 year be 20 people, the age be 40-49 year be 20 people, the age be 50-59 year be 20 people, age be 60-69 year be 20 people, the age be 70-79 year be 20 people; In each age bracket, men and women half and half.According to < < combination of Chinese and Western medicine dermatological > > the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314), judge chilblain.Through clinical use, apply 24 times after the whole rehabilitations of all personnel; Therefore, medicine of the present invention has good therapeutic effect.
Certainly, the medicine of the treatment chilblain described in above-mentioned arbitrary embodiment, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
Certainly, the medicine of the treatment chilblain while having essence, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
Using method of the present invention: the present invention is coated in to chilblain position, and every 12～13 hours once, and at least continuous coating is 6 times, for rotten position, must not contact tap water during coating.
The present invention have make simple, long shelf-life, the advantage such as treatment time is short, medicine of the present invention has fragrance, during patient applies without uncomfortable sensation and untoward reaction; The present invention has long-time drug effect retention, applies number of times still less, and patient cures more convenient and quick.
Therefore, the present invention has following main beneficial effect: make simple, long shelf-life, treatment time is short, have fragrance, treatment cost is low.
The present invention is not limited to above-mentioned preferred forms, should be appreciated that design of the present invention can be by other various forms enforcement utilizations, and they drop in protection scope of the present invention equally.
Claims (10)
1. a medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 3～5 parts, potassium iodide: 3～5 parts, glycerol: 8～12 parts, lanoline: 4～6 parts, Cera Flava: 4～8 parts, vaseline: 50～70 parts, Borneolum Syntheticum: 1.5～5.5 parts, eugenol: 0.5～1.5 part, methyl salicylate: 4～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1～3 part.
2. a medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 4 parts, potassium iodide: 4 parts, glycerol: 10 parts, lanoline: 5 parts, Cera Flava: 6 parts, vaseline: 60 parts, Borneolum Syntheticum: 3 parts, eugenol: 1 part, methyl salicylate: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts.
3. a medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 3 parts, potassium iodide: 3 parts, glycerol: 8 parts, lanoline: 4 parts, Cera Flava: 4 parts, vaseline: 50 parts, Borneolum Syntheticum: 1.5 parts, eugenol: 0.5 part, methyl salicylate: 4 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1 part.
4. a medicine for the treatment of chilblain, it is characterized in that by weight, it includes following raw material: iodine: 5 parts, potassium iodide: 5 parts, glycerol: 12 parts, lanoline: 6 parts, Cera Flava: 8 parts, vaseline: 70 parts, Borneolum Syntheticum: 5.5 parts, eugenol: 1.5 parts, methyl salicylate: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 3 parts.
5. the medicine to any one treatment chilblain described in claim 4 according to claim 1, is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
According to claim 1 to described in claim 4 any one treatment chilblain medicine, it is characterized in that by weight, it also includes 0.5-1.5 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
7. the medicine to any one treatment chilblain described in claim 4 according to claim 1, is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
8. the manufacture method of the medicine for the treatment of chilblain according to claim 7, is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
9. treat according to claim 6 the medicine of chilblain, it is characterized in that it makes by the following method: (1) takes each raw material by weight; (2) Cera Flava, vaseline, methyl salicylate are mixed and heat fused, and be constantly stirred to condensation, obtain base material mixture; (3) get that potassium iodide, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon, Borneolum Syntheticum mixes and carry out porphyrize, add glycerol to grind potassium iodide is dissolved, add iodine to grind it is dissolved, add lanoline to grind well, obtain medicinal mixture; (4) base material mixture is joined in medicinal mixture, and add eugenol and essence, with adding with stirring, stir, cooling, weighing and bagging is obtained the medicine of finished product treatment chilblain.
10. the manufacture method of the medicine for the treatment of chilblain according to claim 9, is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
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| CN201310267521.9A CN103285034B (en) | 2013-07-01 | 2013-07-01 | Medicine for treating chilblain and manufacturing method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067817A (en) * | 1992-05-09 | 1993-01-13 | 朱乃军 | Chilblain spirit ointment, cream and preparation technology thereof |
| CN1204512A (en) * | 1998-07-15 | 1999-01-13 | 湖南省劳动卫生职业病防治研究所 | Medicine for prevention and cure of chilblain |
| CN1977849A (en) * | 2005-12-02 | 2007-06-13 | 天津市世雄科技发展有限公司 | Kibe ointment with bactericidal-bacteriostasis function |
| CN102764417A (en) * | 2012-07-03 | 2012-11-07 | 夏义深 | Chinese materia medica frostbite cream |
-
2013
- 2013-07-01 CN CN201310267521.9A patent/CN103285034B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067817A (en) * | 1992-05-09 | 1993-01-13 | 朱乃军 | Chilblain spirit ointment, cream and preparation technology thereof |
| CN1204512A (en) * | 1998-07-15 | 1999-01-13 | 湖南省劳动卫生职业病防治研究所 | Medicine for prevention and cure of chilblain |
| CN1977849A (en) * | 2005-12-02 | 2007-06-13 | 天津市世雄科技发展有限公司 | Kibe ointment with bactericidal-bacteriostasis function |
| CN102764417A (en) * | 2012-07-03 | 2012-11-07 | 夏义深 | Chinese materia medica frostbite cream |
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