CN103285035B - Medicine for treating dry skin chilblain and manufacturing method thereof - Google Patents
Medicine for treating dry skin chilblain and manufacturing method thereof Download PDFInfo
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- CN103285035B CN103285035B CN201310267522.3A CN201310267522A CN103285035B CN 103285035 B CN103285035 B CN 103285035B CN 201310267522 A CN201310267522 A CN 201310267522A CN 103285035 B CN103285035 B CN 103285035B
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- 208000010445 Chilblains Diseases 0.000 title claims abstract description 51
- 239000003814 drug Substances 0.000 title claims abstract description 47
- 206010013786 Dry skin Diseases 0.000 title claims abstract description 41
- 230000037336 dry skin Effects 0.000 title claims abstract description 41
- 238000004519 manufacturing process Methods 0.000 title abstract description 6
- 229940079593 drug Drugs 0.000 title 1
- 239000000843 powder Substances 0.000 claims abstract description 72
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 60
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 25
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000004327 boric acid Substances 0.000 claims abstract description 25
- 241000772415 Neovison vison Species 0.000 claims abstract description 20
- 229940099259 vaseline Drugs 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 19
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 13
- 241001494479 Pecora Species 0.000 claims abstract description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 24
- 241000283898 Ovis Species 0.000 claims description 24
- 229940025250 camphora Drugs 0.000 claims description 24
- 239000010238 camphora Substances 0.000 claims description 24
- 229910052799 carbon Inorganic materials 0.000 claims description 24
- 238000000227 grinding Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 9
- 241000628997 Flos Species 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 241000283690 Bos taurus Species 0.000 claims description 5
- 241000283707 Capra Species 0.000 claims description 5
- 241000283007 Cervus nippon Species 0.000 claims description 5
- 241000219322 Dianthus Species 0.000 claims description 3
- 239000008868 Flower Essence Substances 0.000 claims description 3
- 235000018958 Gardenia augusta Nutrition 0.000 claims description 3
- 241001632576 Hyacinthus Species 0.000 claims description 3
- 235000014443 Pyrus communis Nutrition 0.000 claims description 3
- 241000775848 Syringa oblata Species 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims 3
- 230000000694 effects Effects 0.000 abstract description 5
- 230000000857 drug effect Effects 0.000 abstract description 4
- 241000270295 Serpentes Species 0.000 abstract description 2
- 241000723346 Cinnamomum camphora Species 0.000 abstract 1
- 235000007889 Osmunda cinnamomea Nutrition 0.000 abstract 1
- 244000239204 Plantago lanceolata Species 0.000 abstract 1
- 235000010503 Plantago lanceolata Nutrition 0.000 abstract 1
- 229960000846 camphor Drugs 0.000 abstract 1
- 229930008380 camphor Natural products 0.000 abstract 1
- 238000003889 chemical engineering Methods 0.000 abstract 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 description 5
- 238000000576 coating method Methods 0.000 description 5
- 208000003251 Pruritus Diseases 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000007803 itching Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000000431 third toe Anatomy 0.000 description 2
- 101710186708 Agglutinin Proteins 0.000 description 1
- 108010091326 Cryoglobulins Proteins 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 101710146024 Horcolin Proteins 0.000 description 1
- 101710189395 Lectin Proteins 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 101710179758 Mannose-specific lectin Proteins 0.000 description 1
- 101710150763 Mannose-specific lectin 1 Proteins 0.000 description 1
- 101710150745 Mannose-specific lectin 2 Proteins 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010047115 Vasculitis Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000000910 agglutinin Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 210000000474 heel Anatomy 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 230000000527 lymphocytic effect Effects 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention belongs to the technical field of medicine chemical engineering, and particularly relates to a medicine for treating dry skin chilblain, which is characterized by comprising the following raw materials in parts by weight: 3-5 parts of camphor, 4-6 parts of boric acid, 6-10 parts of glycerol, 70-85 parts of vaseline, 3-6 parts of mink oil or snake oil, 1.5-2.5 parts of sheep horn powder or ox horn powder or buckhorn powder with the fineness of less than 150 meshes, and 0.5-1.5 parts of methyl p-hydroxy benzoate. The invention also discloses a manufacturing method of the medicine for treating dry skin chilblain. The medicine is suitable for treating dry skin chilblain, and can heal the chilblain quickly; the manufacturing method is simple and easy to master; the medicine is fragrant, and the patient does not have any uncomfortable feeling or untoward effect in the application period; the medicine has the advantages of long drug effect keeping quality period and low application frequency, and can heal the patient more conveniently and quickly.
Description
Technical field
The invention belongs to pharmaceutical chemistry technical field, especially relate to a kind of medicine for the treatment of dry skin chilblain and preparation method thereof.
Background technology
Chilblain is limitation, the infringement of erythema inflammation causing owing to being exposed to subzero cold environment.Chilblain is that the upper confirmation of histology chilblain is a kind of lymphocytic vasculitis to abnormal inflammatory reaction cold, moist, non-freezing environment.Be exposed to cold, moist environment and be and send out frostbitten Major Risk Factors, mostly occur in autumn and winter, especially temperate climate area lowers the temperature sharply and when humid environment, chilblain is more common winter.Not having, the area of central-heating is the most common.Women, child and old man often get involved, and child may be relevant with cryoglobulin or cold agglutinin.Show as single or multiple swelling scarlet or kermesinus macule, pimple or tuberosity, the visible vesicle of severe patient and ulcer.Conventionally companion's pruritus or burn feeling, predilection site is finger, toes, heel, thigh, nose and ear.Natural history can continue several weeks, has self limiting.
The domestic research for chilblain medicine has for many years and has a large amount of achievements in research, as the patent No. is: 200710168576.9, denomination of invention is: a kind of medicine for external use of anti-treating chilblain; For another example profit number is: 201110265936.3, denomination of invention is: snake oil liniment for preventing chilblain; Etc., still, not very good really for the therapeutic effect of chilblain, and be not to customize for the personnel of dry skin, therefore, effect is not good enough.
Summary of the invention
For addressing the above problem, the object of the invention is to disclose a kind of medicine for the treatment of dry skin chilblain, it is very suitable for the personnel of dry skin, and therapeutic effect is fairly good, and treatment time is short; Further, the present invention also discloses its manufacture method, and the present invention realizes by the following technical solutions.
A kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 3～5 parts, boric acid: 4～6 parts, glycerol: 6～10 parts, vaseline: 70～85 parts, mink oil or Adeps Serpentis: 3～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5～2.5 parts, methyl hydroxybenzoate: 0.5～1.5 part.
In first embodiment of the present invention, a kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 4 parts, boric acid: 5 parts, glycerol: 8 parts, vaseline: 75 parts, mink oil or Adeps Serpentis: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts, methyl hydroxybenzoate: 1 part.
In second embodiment of the present invention, a kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 3 parts, boric acid: 4 parts, glycerol: 6 parts, vaseline: 70 parts, mink oil or Adeps Serpentis: 3 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5 parts, methyl hydroxybenzoate: 0.5 part.
In the 3rd embodiment of the present invention, a kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 5 parts, boric acid: 6 parts, glycerol: 10 parts, vaseline: 85 parts, mink oil or Adeps Serpentis: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2.5 parts, methyl hydroxybenzoate: 1.5 parts.
The medicine for the treatment of dry skin chilblain described above, wherein said Cornu Caprae seu Ovis powder is the powder that the angle of goat or sheep or Saigae Tataricae is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
The medicine of above-mentioned treatment dry skin chilblain, it is characterized in that by weight, it also includes 1-3 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
The medicine of above-mentioned treatment dry skin chilblain, is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (5) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product.
The medicine of above-mentioned treatment dry skin chilblain, is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (6), while being cooled to 45 ± 5 DEG C, add essence to stir; (6) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product.
Using method of the present invention: the present invention is coated in to chilblain position, and every 10～12 hours once, at least continuous coating 6 times, for rotten position, must not contact tap water during coating.
The present invention has following main beneficial effect: be applicable to the treatment of dry skin chilblain, healing speed is fast, and manufacture method simply, easily grasp; And medicine has fragrance, during applying, patient feels and untoward reaction without uncomfortable; The present invention has long-time drug effect retention, applies number of times few, and patient cures more convenient and quick.
Detailed description of the invention
embodiment 1
A kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 4 parts, boric acid: 5 parts, glycerol: 8 parts, vaseline: 75 parts, mink oil or Adeps Serpentis: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts, methyl hydroxybenzoate: 1 part.
embodiment 2
A kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 3 parts, boric acid: 4 parts, glycerol: 6 parts, vaseline: 70 parts, mink oil or Adeps Serpentis: 3 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5 parts, methyl hydroxybenzoate: 0.5 part.
embodiment 3
A kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 5 parts, boric acid: 6 parts, glycerol: 10 parts, vaseline: 85 parts, mink oil or Adeps Serpentis: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2.5 parts, methyl hydroxybenzoate: 1.5 parts.
Described in above-mentioned arbitrary embodiment, treat the medicine of dry skin chilblain, wherein said Cornu Caprae seu Ovis powder is the powder that the angle of goat or sheep or Saigae Tataricae is pulverized and formed after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
Described in above-mentioned arbitrary embodiment, treat the medicine of dry skin chilblain, it is characterized in that by weight, it also includes 1-3 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
The applicant is through repeated tests and clinical practice, find to adopt the medicine of following formula, can reach the application's object: a kind of medicine for the treatment of dry skin chilblain, it is characterized in that by weight, it includes following raw material: Camphora: 3～5 parts, boric acid: 4～6 parts, glycerol: 6～10 parts, vaseline: 70～85 parts, mink oil or Adeps Serpentis: 3～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5～2.5 parts, methyl hydroxybenzoate: 0.5～1.5 part.
The medicine of above-mentioned treatment dry skin chilblain, is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (5) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product.
The medicine of above-mentioned treatment dry skin chilblain, is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (6), while being cooled to 45 ± 5 DEG C, add essence to stir; (6) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product.
Using method of the present invention: the present invention is coated in to chilblain position, and every 10～12 hours once, at least continuous coating 6 times, for rotten position, must not contact tap water during coating.
The present invention has following main beneficial effect: be applicable to the treatment of dry skin chilblain, healing speed is fast, and manufacture method simply, easily grasp; And medicine has fragrance, during applying, patient feels and untoward reaction without uncomfortable; The present invention has long-time drug effect retention, applies number of times few, and patient cures more convenient and quick.
The present invention is by following clinical trial: tests for 240 patients, and points two groups, wherein first group of 120 male by name, second group of 120 women by name; In every group the age be 7-15 year be 20 people, the age be 16-25 year be 20 people, the age be 26-35 year be 20 people, the age be 36-45 year be 20 people, the age be 46-55 year be 20 people, the age be 56-80 year be 20 people.Judge chilblain according to " combination of Chinese and Western medicine dermatological " the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996, the 313-314).In first group, that fester is 15 people, and other is the swollen pain of itching, be all hands, face, middle toe and sufficient heel, applying what entirely heal afterwards for 6 times is 114 people, and applying what entirely heal afterwards for 8 times is 118 people, applying what entirely heal afterwards for 10 times is 120 people, fester be 15 people apply before the 11st time all complete; In second group, that fester is 20 people, and other is the swollen pain of itching, be all hands, face, middle toe and sufficient heel, applying what entirely heal afterwards for 6 times is 106 people, and applying what entirely heal afterwards for 8 times is 115 people, applying what entirely heal afterwards for 10 times is 120 people, fester be 20 people apply before the 11st time all complete.Therefore, in 5 days, patient has all obtained recovery, and total effective rate has reached 100%, has reached good clinical effectiveness.
In addition, adopt embodiment 1 to test for other three crowdes of 240 patients respectively to embodiment 3, result of the test is in 5 days, and patient has all obtained recovery.
In the present invention, owing to having vaseline, glycerol etc., therefore medicine is had to good drug effect retention effect, the interval of twice coating has reached 12 hours.
Cornu Caprae seu Ovis powder in the present invention or horn powder or harts horn carbon have the loose pain that swells, unstings, go the effect of itching.
Mink oil in the present invention or Adeps Serpentis have good resisting cold effect.
The present invention is not limited to above-mentioned preferred forms, should be appreciated that design of the present invention can be by other various forms enforcement utilizations, and they drop in protection scope of the present invention equally.
Claims (8)
1. treat the medicine of dry skin chilblain for one kind, it is characterized in that by weight, it includes following raw material: Camphora: 3～5 parts, boric acid: 4～6 parts, glycerol: 6～10 parts, vaseline: 70～85 parts, mink oil or Adeps Serpentis: 3～6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5～2.5 parts, methyl hydroxybenzoate: 0.5～1.5 part.
2. treat the medicine of dry skin chilblain for one kind, it is characterized in that by weight, it includes following raw material: Camphora: 4 parts, boric acid: 5 parts, glycerol: 8 parts, vaseline: 75 parts, mink oil or Adeps Serpentis: 5 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2 parts, methyl hydroxybenzoate: 1 part.
3. treat the medicine of dry skin chilblain for one kind, it is characterized in that by weight, it includes following raw material: Camphora: 3 parts, boric acid: 4 parts, glycerol: 6 parts, vaseline: 70 parts, mink oil or Adeps Serpentis: 3 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 1.5 parts, methyl hydroxybenzoate: 0.5 part.
4. treat the medicine of dry skin chilblain for one kind, it is characterized in that by weight, it includes following raw material: Camphora: 5 parts, boric acid: 6 parts, glycerol: 10 parts, vaseline: 85 parts, mink oil or Adeps Serpentis: 6 parts, fineness are less than 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon: 2.5 parts, methyl hydroxybenzoate: 1.5 parts.
5. the medicine to any one treatment dry skin chilblain described in claim 4 according to claim 1, is characterized in that described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
6. the medicine to any one treatment dry skin chilblain described in claim 4 according to claim 1, it is characterized in that by weight, it also includes 1-3 part essence, and described essence is jasmin essence or Syringa oblata Lindl. essence or orange taste essence or Dianthus carryophyllus essence or hyacinth essence or Flos Mume essence or Flos persicae essence or pear flower essence.
7. the medicine to any one treatment dry skin chilblain described in claim 4 according to claim 1, is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (5) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product; Wherein, described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
8. treat according to claim 6 the medicine of dry skin chilblain, it is characterized in that it makes by the following method: (1) each raw material of weighing by weight; (2) Camphora, boric acid are ground into fineness and are less than 150 object fine powders; (3) Camphora, boric acid, fineness being less than to 150 object Cornu Caprae seu Ovis powder or horn powder or harts horn carbon and glycerol mixes; (4) mink oil or Adeps Serpentis, vaseline added and stirred, being warmed up to 80 ± 5 DEG C, continuing to stir; (6), while being cooled to 45 ± 5 DEG C, add essence to stir; (6) the cool to room temperature time packaging medicine for the treatment of dry skin chilblain that gets product; Wherein, described Cornu Caprae seu Ovis powder is the angle pulverizing of goat or sheep or Saigae Tataricae the powder forming after grinding; Described horn powder is the powder that the angle of Babalus bubalis L. or cattle is pulverized and formed after grinding; Described harts horn carbon is the powder that the angle of elk or Cervus nippon Temminck is pulverized and formed after grinding.
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| CN201310267522.3A CN103285035B (en) | 2013-07-01 | 2013-07-01 | Medicine for treating dry skin chilblain and manufacturing method thereof |
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| CN201310267522.3A CN103285035B (en) | 2013-07-01 | 2013-07-01 | Medicine for treating dry skin chilblain and manufacturing method thereof |
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| CN1105559A (en) * | 1993-04-27 | 1995-07-26 | 宁波市倍的福日化总厂 | Marten oil frost-proof chap-curing skin-care cream and preparation method thereof |
| CN102370777A (en) * | 2011-11-26 | 2012-03-14 | 王成斌 | Medicament for treating non-ulcerated chilblains |
| CN102416064A (en) * | 2011-11-26 | 2012-04-18 | 王成斌 | Medicine for treating ulcerated chilblain |
| CN102670781A (en) * | 2012-04-17 | 2012-09-19 | 杨泽田 | Hand-protecting snake oil liniment |
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