CN103272187A - Agent for curing liver cancer - Google Patents
Agent for curing liver cancer Download PDFInfo
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- CN103272187A CN103272187A CN2013102412764A CN201310241276A CN103272187A CN 103272187 A CN103272187 A CN 103272187A CN 2013102412764 A CN2013102412764 A CN 2013102412764A CN 201310241276 A CN201310241276 A CN 201310241276A CN 103272187 A CN103272187 A CN 103272187A
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Abstract
The invention relates to an agent for curing a liver cancer. The agent contains the following materials in ratio by weight: 50-70 parts of carapax trionycis, 10-15 parts of radix paeoniae rubra, 10-15 parts of radix curcumae, 20-30 parts of radix salviae miltiorrhizae, 5-7 parts of paris polyphylla, 20-30 parts of barbed skullcap herb, 20-25 parts of whitebackleaf mallotus root, 7-10 parts of common sage herb, 10-15 parts of cortex lycii radicis, 3-5 parts of leech, 20-30 parts of pungent oleaster root, 10-15 parts of capillary wormwood herb, 15-25 parts of hypericum japonicum, 7-13 parts of rheum officinale, 7-10 parts of fructus aurantii, 10-15 parts of hemsley rockvine root, 15-20 parts of stenoloma chusana, 7-10 parts of radix scutellariae, 25-30 parts of euonymus bungeanus, 15-25 parts of goldhair hedyotis herb, 100-150 parts of red date, 10-30 parts of schisandra chinensis and 1-10 parts of liquorice. The agent for curing the liver cancer has the characteristics of low cost, easy preparation, small toxic and side effects and significant effect.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicament for the treatment of hepatocarcinoma.
Background technology
Tumor is one of current medical circle the most thorny persistent ailment of generally acknowledging, the sickness rate height is to people's life and health harm and big.At present, the method for clinical treatment malignant tumor has five kinds usually: operation, radiotherapy, chemotherapy, Biotherapeutics, traditional Chinese medical herbal treatment.Wherein, operation, radiotherapy all are topical therapeutics, and the patient with advanced cancer that shifts, is diffused into its internal organs organ is not just had too big therapeutical effect; Though chemotherapy is the treatment of general, can only eliminate a certain proportion of tumor cell, the part tumor cell that left behind is very fast again can growth and breeding.And chemotherapeutics also can kill and wound a large amount of human normal cells when killing tumor cell, and the vitals functions such as internal organs of human body are badly damaged, and suppresses or destroy the immune system of human body simultaneously again.Biotherapeutics can be eliminated remaining tumor cell, but must be to this medicaments insensitive, is not a lot of but also require tumor cell quantity; Common traditional Chinese medical herbal treatment, medication is used for the not enough system of medication and simple Chinese herbal medicine great majority all are water miscible medicines, after they are absorbed by body, be difficult to arrive the tumor focus core, (fat is exactly oils and fats more to be difficult to permeate, wear out the after birth of the tumor cell that protein and membrane lipid constitute, because " water oil is immiscible "), so traditional Chinese herbal treatment tumor efficiency is poor.And the formation cause of disease of tumor is very complicated, both can be poisoning intrusion, can be again the long-time stimulus of chronic inflammatory disease, also has other factors to cause cell mutation etc., thus must Synergistic treatment in treatment clinical course, just can obtain better therapeutic effect.The generation mechanism of hepatic ascites, hydrothorax is very complicated, and common reason is hypoproteinemia, and medical science Therapeutic Method commonly used is exactly filler albumen, takes or inject diuretic now, perhaps draws water.These Therapeutic Method are often all cured the symptoms, not the disease, even can cause more complication.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of hepatocarcinoma.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of hepatocarcinoma, it comprises following materials by weight: Carapax Trionycis 50-70 part, Radix Paeoniae Rubra 10-15 part, Radix Curcumae 10-15 part, Radix Salviae Miltiorrhizae 20-30 part, Rhizoma Paridis 5-7 part, Herba Scutellariae Barbatae 20-30 part, Folium Malloti Apeltae 20-25 part, Herba Salviae Plebeiae 7-10 part, Cortex Lycii 10-15 part, Hirudo 3-5 part, Radix Elaeagni 20-30 part, Herba Artemisiae Scopariae 10-15 part, Herba Hyperici Japonici 15-25 part, Radix Et Rhizoma Rhei 7-13 part, Fructus Aurantii 7-10 part, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 10-15 part, Folium Stenolomatis 15-20 part, Radix Scutellariae 7-10 part, Herba Euonymi Bungeani 25-30 part, Herba Hedyotidis Chrysotrichae 15-25 part, Fructus Jujubae 100-150 part, Fructus Schisandrae Chinensis 10-30 part and Radix Glycyrrhizae 1-10 part.
Preferably, the medicament for the treatment of hepatocarcinoma of the present invention comprises following materials by weight: 5 parts in 60 parts of Carapax Trionycis, 13 parts of Radix Paeoniae Rubra, 13 parts of Radix Curcumaes, 25 parts of Radix Salviae Miltiorrhizaes, 6 parts of Rhizoma Paridis, 25 parts of Herba Scutellariae Barbataes, 23 parts of Folium Malloti Apeltaes, 8 parts of Herba Salviae Plebeiaes, 12 parts of Cortex Lycii, 4 parts of Hirudos, 25 parts of Radix Elaeagnis, 13 parts of Herba Artemisiae Scopariaes, 20 parts of Herba Hyperici Japonici, 10 parts of Radix Et Rhizoma Rhei, 8 parts of Fructus Aurantiis, 12 parts of Radix Apioris Fortunei (Radix Lespedezae Buergeri)s, 18 parts of Folium Stenolomatiss, 9 parts of Radix Scutellariaes, 28 parts of Herba Euonymi Bungeani, 20 parts of Herba Hedyotidis Chrysotrichaes, 120 parts of Fructus Jujubaes, 20 parts of Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
More preferably, the medicament for the treatment of hepatocarcinoma of the present invention also comprises following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
More preferably, described medicament can be tablet, dispersible tablet, decoction or capsule.
In the present invention:
Folium Malloti Apeltae
Source: for Euphorbiaceae Mallotus plant Folium Malloti Apeltae Mallotusapelta (Lour.) Muell.Arg. is used as medicine with root and leaf.Root can be adopted the whole year, cleans, and section is dried.The many using fresh herbs of leaf, or summer, autumn gather, dry levigation.
Nature and flavor: little hardship, puckery, flat.
Function cures mainly: root: easing the affected liver is invigorated blood circulation, invigorating the spleen for eliminating dampness, and convergence is taken off admittedly.Be used for chronic hepatitis, hepatosplenomegaly, uterine prolapse, proctoptosis, leucorrhea, edema during pregnancy.Leaf: anti-inflammation hemostasia.Otitis media is controlled in external, furuncle and phyma, traumatic injury, traumatic hemorrhage.
Herba Salviae Plebeiae
Latin formal name used at school: Saluia plebeia R.Br.
Boundary: plant kingdom
Section: lip
Belong to: Salvia japonica Thunb.
(English) Common Sage Herb
[source]: be the aerial parts of labiate Herba Salviae Plebeiae Salvia plebeia.Gather 6～July, cleans, and chops up using fresh herb or dry.
Radix Elaeagni is the root of Fructus Elaeagni, wherein
Chinese: Fructus Elaeagni
Foreign language title: E.pungens
Boundary: plant kingdom
Door: Angiospermae
Guiding principle: Dicotyledoneae
Order: Rosales
Section: Elaeagnaceae
Belong to: Elaeagnus Elaeagnus
Herba Hyperici Japonici
[plant name] Herba Hyperici Japonici Hypericum japonicum Thunb.ex Murray (Hypericaceae)
[meridian distribution of property and flavor] sweet, little hardship, cold.Return Liver Channel.
[function cures mainly] herb: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, eliminating stasis to stop pain is used for hepatitis, early stage liver cirrhosis, appendicitis, eye conjunctivitis, tonsillitis.Carbuncle furuncle and phyma poison, herpes zoster, venom, traumatic injury are controlled in external.
Radix Apioris Fortunei (Radix Lespedezae Buergeri)
Boundary: plant kingdom
Door: Angiospermae (Magnoliophyta)
Guiding principle: Dicotyledoneae (Magnoliopsida)
Subclass: Rosidae (Rosidae)
Order: the Fructus Vitis viniferae order also has data to be classified as Rhamnales
Section: Vitaceae (Vitaceae)
Belong to: Calamus (Albertisia Becc.) is climbed on the precipice
Kind: for climbing Calamus plant Radix Apioris Fortunei (Radix Lespedezae Buergeri) in the Vitaceae precipice
Folium Stenolomatis
Latin formal name used at school: Stenoloma chusanum Ching
Boundary: plant kingdom
Door: Pteridophyta
Guiding principle: thin capsule Filicopsida
Order: Rhizoma Polypodiodis Nipponicae order
Section: Lindsaeaceae
Belong to: Xiao crow Cyclosorus
Kind: Folium Stenolomatis
Chinese Plants will: 2:275
Herba Euonymi Bungeani
Binomial nomenclature: Euonymus bungeanus
Boundary: plant kingdom
Door: Angiospermae
Guiding principle: Dicotyledoneae
Subclass: Rosidae
Order: Celastrales
Section: Celastraceae
Belong to: Euonymus
Kind: Herba Euonymi Bungeani
Herba Hedyotidis Chrysotrichae
[English name] Goldhair Hedyotis Herb
[latin name] Herba Hedyotidis Chrysotrichae
The herb of [source] Rubiaceae cerastium plant Herba Hedyotidis Chrysotrichae Hedyotis chrysotricha (Palib.) Merr..Can adopt the whole year.Clean using fresh herb or dry.
[meridian distribution of property and flavor] hardship, cold.
The medicament for the treatment of hepatocarcinoma of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
The specific embodiment
Embodiment 1:
Take by weighing Carapax Trionycis 60 grams, Radix Paeoniae Rubra 13 grams, Radix Curcumae 13 grams, Radix Salviae Miltiorrhizae 25 grams, Rhizoma Paridis 6 grams, Herba Scutellariae Barbatae 25 grams, Folium Malloti Apeltae 23 grams, Herba Salviae Plebeiae 8 grams, Cortex Lycii 12 grams, Hirudo 4 grams, Radix Elaeagni 25 grams, Herba Artemisiae Scopariae 13 grams, Herba Hyperici Japonici 20 grams, Radix Et Rhizoma Rhei 10 grams, Fructus Aurantii 8 grams, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 12 grams, Folium Stenolomatis 18 grams, Radix Scutellariae 9 grams, Herba Euonymi Bungeani 28 grams, Herba Hedyotidis Chrysotrichae 20 grams, Fructus Jujubae 120 grams, Fructus Schisandrae Chinensis 20 grams and Radix Glycyrrhizae 5 grams, add water 5000 milliliters, heating is 5 hours under the condition of reflux, filter, filtrate is concentrated into 800 milliliters, be cooled to room temperature, namely get decoction of the present invention.
Embodiment 2:
Take by weighing Carapax Trionycis 60 grams, Radix Paeoniae Rubra 13 grams, Radix Curcumae 13 grams, Radix Salviae Miltiorrhizae 25 grams, Rhizoma Paridis 6 grams, Herba Scutellariae Barbatae 25 grams, Folium Malloti Apeltae 23 grams, Herba Salviae Plebeiae 8 grams, Cortex Lycii 12 grams, Hirudo 4 grams, Radix Elaeagni 25 grams, Herba Artemisiae Scopariae 13 grams, Herba Hyperici Japonici 20 grams, Radix Et Rhizoma Rhei 10 grams, Fructus Aurantii 8 grams, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 12 grams, Folium Stenolomatis 18 grams, Radix Scutellariae 9 grams, Herba Euonymi Bungeani 28 grams, Herba Hedyotidis Chrysotrichae 20 grams, Fructus Jujubae 120 grams, Fructus Schisandrae Chinensis 20 grams, Radix Glycyrrhizae 5 grams, Fructus Broussonetiae 5 grams, RADIX PEUCEDANI 3 gram Herba Thlaspiss 6 grams, Rhizoma Smilacis Chinensis 5 grams, Herba Cichorii 7 gram Rhizoma Dioscoreae Septemlobaes 4 gram Herba Siegesbeckiaes 6 grams, Herba Gendarussae 3 grams, Cortex Syingae Amurensis 5 grams, Herba pterocephali 3 grams, Nodus Nelumbinis Rhizomatis 3 grams, Medulla Stachyuri (Medulla Helwingiae) 7 grams, Flos Bombacis Malabarici 4 grams, Concha Arcae 5 grams, Caulis Mahoniae 3 grams, Folium Sauropi 6 grams, Semen Lablab Album 7 grams, Retinervus Luffae Fructus 3 grams, Herba Polygoni cymosi 5 grams, Semen Celosiae 3 grams and Fructus Litseae 5 grams, add water 8000 milliliters, heating is 5 hours under the condition of reflux, filter, filtrate is concentrated into 800 milliliters, be cooled to room temperature, namely get decoction of the present invention.
Experimental example
1.1 physical data by the diagnosis of primary hepatocarcinoma in " Chinese common cancer diagnosis and treatment standard " and domestic clinical stages standard, select be II, III phase by stages, Karnofsky scoring 〉=60 minutes, Patients with Primary 30 examples of expectation life cycle 〉=3.All case is inpatient, all wears pathologic finding through liver and makes a definite diagnosis.Male 25 examples wherein, women 5 examples; Age 34-67 year, average 51.3 years old.Be divided into two groups, every group of 15 routine patients, two groups of there was no significant differences (P＞0.05) in side such as sex, age, the course of disease, state of an illness scoring and relatively have comparability.
The decoction of first group of oral embodiment 1 preparation of patient, every day twice, each oral 100 milliliters.Took continuously 6 months.
The decoction of second group of oral embodiment 2 preparation of patient, every day twice, each oral 100 milliliters.Took continuously 6 months.
Criterion of therapeutical effect
The objective efficacy assessment standard of solid tumor: the objective therapeutic evaluation standard of formulating according to WHO of solid tumor (the Sun Yan chief editor. medical oncology. Beijing: the People's Health Publisher, 2001.994-996).Clinical primary symptom integration evaluation criteria: produce effects: treatment rear section transference cure, the Karnofsky integration reduces 〉=2/3; Effectively: treatment back symptom takes a turn for the better, and the Karnofsky integration reduces 〉=1/3, but＜2/3; Invalid: treatment back symptom does not have obvious improvement, the constant or Karnofsky integration reduction＜1/3 of Karnofsky integration.Karnofsky scoring according to " situation score standard in the body " (the Sun Yan chief editor. medical oncology. Beijing: the People's Health Publisher, 2001.994-996) calculate.
Therapeutic outcome
Among first group of patient, produce effects 5 examples, effective 7 examples, invalid 3 examples; Among second group of patient, produce effects 9 examples, effective 6 examples.
Claims (4)
1. a medicament for the treatment of hepatocarcinoma is characterized in that it comprises following materials by weight: Carapax Trionycis 50-70 part, Radix Paeoniae Rubra 10-15 part, Radix Curcumae 10-15 part, Radix Salviae Miltiorrhizae 20-30 part, Rhizoma Paridis 5-7 part, Herba Scutellariae Barbatae 20-30 part, Folium Malloti Apeltae 20-25 part, Herba Salviae Plebeiae 7-10 part, Cortex Lycii 10-15 part, Hirudo 3-5 part, Radix Elaeagni 20-30 part, Herba Artemisiae Scopariae 10-15 part, Herba Hyperici Japonici 15-25 part, Radix Et Rhizoma Rhei 7-13 part, Fructus Aurantii 7-10 part, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 10-15 part, Folium Stenolomatis 15-20 part, Radix Scutellariae 7-10 part, Herba Euonymi Bungeani 25-30 part, Herba Hedyotidis Chrysotrichae 15-25 part, Fructus Jujubae 100-150 part, Fructus Schisandrae Chinensis 10-30 part and Radix Glycyrrhizae 1-10 part.
2. the medicament for the treatment of hepatocarcinoma according to claim 1 is characterized in that it comprises following materials by weight: 5 parts in 60 parts of Carapax Trionycis, 13 parts of Radix Paeoniae Rubra, 13 parts of Radix Curcumaes, 25 parts of Radix Salviae Miltiorrhizaes, 6 parts of Rhizoma Paridis, 25 parts of Herba Scutellariae Barbataes, 23 parts of Folium Malloti Apeltaes, 8 parts of Herba Salviae Plebeiaes, 12 parts of Cortex Lycii, 4 parts of Hirudos, 25 parts of Radix Elaeagnis, 13 parts of Herba Artemisiae Scopariaes, 20 parts of Herba Hyperici Japonici, 10 parts of Radix Et Rhizoma Rhei, 8 parts of Fructus Aurantiis, 12 parts of Radix Apioris Fortunei (Radix Lespedezae Buergeri)s, 18 parts of Folium Stenolomatiss, 9 parts of Radix Scutellariaes, 28 parts of Herba Euonymi Bungeani, 20 parts of Herba Hedyotidis Chrysotrichaes, 120 parts of Fructus Jujubaes, 20 parts of Fructus Schisandrae Chinensis and Radix Glycyrrhizae.
3. the medicament for the treatment of hepatocarcinoma according to claim 1 and 2 is characterized in that also comprising following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
4. according to the medicament of each described treatment hepatocarcinoma in the claim 1 to 3, it is characterized in that described medicament can be tablet, dispersible tablet, decoction or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310241276.4A CN103272187B (en) | 2013-06-19 | 2013-06-19 | Agent for curing liver cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310241276.4A CN103272187B (en) | 2013-06-19 | 2013-06-19 | Agent for curing liver cancer |
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| Publication Number | Publication Date |
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| CN103272187A true CN103272187A (en) | 2013-09-04 |
| CN103272187B CN103272187B (en) | 2014-10-08 |
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| CN201310241276.4A Active CN103272187B (en) | 2013-06-19 | 2013-06-19 | Agent for curing liver cancer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853816A (en) * | 2016-06-15 | 2016-08-17 | 马德亮 | Pharmaceutical preparation for treating liver cancer and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1160559A (en) * | 1996-11-30 | 1997-10-01 | 李泽良 | Hepatitis B curing toxin-dissipating pill |
| CN1559576A (en) * | 2004-02-25 | 2005-01-05 | 陈绍先 | Chinese herbal medicine prescription for treating liver cancer, lung cancer, blood cancer, stomach cancer and cardia cancer and its formulating method |
-
2013
- 2013-06-19 CN CN201310241276.4A patent/CN103272187B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1160559A (en) * | 1996-11-30 | 1997-10-01 | 李泽良 | Hepatitis B curing toxin-dissipating pill |
| CN1559576A (en) * | 2004-02-25 | 2005-01-05 | 陈绍先 | Chinese herbal medicine prescription for treating liver cancer, lung cancer, blood cancer, stomach cancer and cardia cancer and its formulating method |
Non-Patent Citations (1)
| Title |
|---|
| 陈永武等: "清肝解毒汤配合甘利欣治疗慢性乙型肝炎的疗效观察", 《中国热带医学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853816A (en) * | 2016-06-15 | 2016-08-17 | 马德亮 | Pharmaceutical preparation for treating liver cancer and application thereof |
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| CN103272187B (en) | 2014-10-08 |
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