CN103271032A - Bactericide composition containing SYP-1620 - Google Patents
Bactericide composition containing SYP-1620 Download PDFInfo
- Publication number
- CN103271032A CN103271032A CN2013102331998A CN201310233199A CN103271032A CN 103271032 A CN103271032 A CN 103271032A CN 2013102331998 A CN2013102331998 A CN 2013102331998A CN 201310233199 A CN201310233199 A CN 201310233199A CN 103271032 A CN103271032 A CN 103271032A
- Authority
- CN
- China
- Prior art keywords
- alkene oxime
- oxime amine
- amine
- rabcide
- bactericide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention discloses a bactericide composition containing SYP-1620. Effective active ingredients include SYP-1620 and rabcide in a weight ratio of 1:20-20:1. The composition can be prepared into a water dispersible granule, wettable powder, a suspending agent, a suspended seed coating and a granule which are allowed in agriculture. The bactericide composition containing SYP-1620 has reasonable components, good bactericide effect and low medication cost; further, the activity and the bactericide effect are not simple addition of the activity of each component, and compared with conventional single preparations, the bactericide composition containing SYP-1620 has remarkable bactericide effect and synergistic effect, has no pollution to crops and good safety, and meets the safety requirement of pesticide preparations; therefore, the bactericide composition containing SYP-1620 has a remarkable control effect on rice blast.
Description
Technical field
Patent application of the present invention is that invention and created name is a kind of bactericidal composition that contains alkene oxime amine, and application number is 201210173315.7, and the applying date is dividing an application of 20120531 patent applications.
The present invention relates to a kind of bactericidal composition that contains alkene oxime amine, particularly contain alkene oxime amine as first active component a kind of comprising, be selected from the different metsulfovax, ring propionyl bacterium amine, Rabcide, Tebufloquin of control rice blast bactericide as the bactericidal composition of second active component, belong to technical field of compounded pesticide.
Background technology
Alkene oxime amine, chemical name: (E, E, E)-and N-methyl-2-[((((1-methyl-3-(2, the 6-dichlorophenyl)-the 2-acrylic) imino group) the oxygen base) methyl) phenyl]-the 2-methoxyimino acetic amide.Alkene oxime amine is the methoxy acrylic bactericide by Shenyang Chemical Engineering Inst's exploitation, has unique mechanism of action, and it suppresses its mitochondrial respiratory by the electronics transmission between pinning cytochrome b and the c1 and brings into play bacteriostasis.Its fungicidal spectrum is wide, active high, can be used for preventing and treating plurality of plant diseases such as wheat rust, wheat powdery mildew, rice sheath blight disease, false smut, powdery mildew of cucumber, cucumber downy mildew, downy mildew of garpe, alternaria leaf spot of apple, apple mildew, sigatoka, early blight of tomato, pear scab, powdery mildew of strawberry, rust of sunflower.Although this bactericide mechanism of action uniqueness, pathogen is also very fast to the speed that it produces resistance, and the use cost height is promoted the use of so limited the large tracts of land of alkene oxime amine.
Rice blast is one of important disease of paddy rice, can cause the underproduction significantly, the underproduction 40%～50% when serious, even No kernels or seeds are gathered, as in a year of scarcity.All there is generation in each rice district, the world.Introduce several pesticide species that can be used for preventing and treating rice blast below:
Different metsulfovax, English common name isotianil, chemical name: 3,4-two chloro-N-(2-cyano-phenyl)-5-isothiazole formamide are the isothiazole carboxamides that the common research and development of Bayer and Sumitomo Chemical are used for preventing and treating rice blast.Characteristics are that it does not produce direct antibacterial action to pathogen, but by exciting paddy rice self to the natural immunology defense of rice blast, reach the purpose of opposing rice blast.
Ring propionyl bacterium amine, English common name fenhexamid is a kind of acid amide fungicides, belongs to interior suction, protective fungicide.Different with existing bactericide, no bactericidal activity does not suppress the growth of pathogen mycelia.Be mainly used in rice field control rice blast.
Rabcide has another name called rabcide, English common name fthalide, chemical name: 4,5,6,7-Rabcide.Being the organochlorine bactericide, is the foliage spray protectant, has impermeabilisation and disturbs melanin biosynthesis effect, is mainly used in preventing and treating rice blast.
Tebufloquin(test code number OK-02, SN4524), chemical name: 6-tert-butyl-8-fluoro-2,3-dimethyl-4-quinolyl acetate, it is the quinoline bactericide by Meiji Pharmaceutial Ltd.'s exploitation, mainly rice blast and banded sclerotial blight there are extraordinary preventive effect, also can be used for the control of soybean and vegetable disease.
Although alkene oxime amine is a kind of disinfectant use in agriculture of high-efficiency broad spectrum, it is as methoxy acrylic ester compounds, and the mechanism of action is single, and germ is reused in the field for a long time can produce resistance, causes preventive effect to reduce, and the use cost height.Exist resistance risk after the different metsulfovax of the bactericide of above-mentioned several control rice blast, ring propionyl bacterium amine, Rabcide, the Tebufloquin listing.The inventor finds by test; the alkene oxime amine that the mechanism of action is different is bactericide compounded with the control rice blast, has obvious synergistic effect, can significantly improve control efficiency, the minimizing dosage for the treatment of, protection; reduce the control cost, to the crop safety height.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, synergistic effect is remarkable, and bactericidal effect is good, and drug cost is low, to the agricultural bactericidal composition of crop safety.
Another object of the present invention is to provide the application of above-mentioned composition on the control rice blast.
In order to overcome the defective of existing unitary agent, technical scheme of the present invention is to solve like this:
A) the first active component alkene oxime amine;
B) second active component is selected from different metsulfovax, ring propionyl bacterium amine, Rabcide, the Tebufloquin of control rice blast bactericide;
The weight ratio of first active component and second active component is 1:20～20:1, is preferably 1:10-10:1, and more preferably 1:5～5:1 most preferably is 1:2～2:1.
The cumulant of first active component and second active component is 5%～90% of described composition total weight, is preferably 8%～75%.
The preparation formulation that bactericidal composition of the present invention can be prepared according to method known in those skilled in the art is water dispersible granules, wetting powder, suspending agent, suspension seed-coating agent, granule.
For water dispersible granules, those skilled in the art are familiar with the corresponding auxiliary agent of use and finish the present invention very much.In dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In disintegrant such as ammonium sulfate, urea, sucrose, the glucose one or more; In binding agent such as diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family one or more; Filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To wetting powder, spendable auxiliary agent has: in dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate (dispersing agent NNO), TERSPERSE 2020(U.S. Huntsman Corporation produce the alkyl naphthalene sulfonic acid salt) in one or more; The polyoxyethylene sorbitan stearate), agricultural newborn 1601#(common name Span60), Tween-60 #(common name alkyl phenol formaldehyde resin polyoxyethylene ether), farming breast 2201, this dish-60#(common name emulsifier such as Nongru-700 #(common name:::: triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer), TERSPERSE 4894(U.S. Huntsman Corporation produces) in one or more; Wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500(U.S. Huntsman Corporation produce) in one or more; In thickener such as xanthans, polyvinyl alcohol, bentonite, the aluminium-magnesium silicate one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; Defoamer such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more; Water is deionized water.
To suspension seed-coating agent, spendable auxiliary agent has: binding agent such as polysaccharose macromolecular compound (soluble starch, polypropylene graft copolymer, xanthan gum, the microorganism mucilage), cellulose derivatives (hydroxypropyl methylcellulose, sodium carboxymethylcellulose, ethyl cellulose), seaweeds such as sodium alginate, agar, rosin, paraffin, gelatin, pectin, polyvinyl alcohol, polyethylene glycol, polyvinyl acetate, polyacrylamide, the water-soluble composite of polyvinylpyrrolidone and polyhydric alcohol polymer, inorganic binder (aluminium-magnesium silicate, clay, waterglass, gypsum) in one or more; Among dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, the TERSPERSE 2020 one or more; The sorbitan monostearate APEO), among agricultural newborn 1601#, the TERSPERSE 4894 one or more emulsifier such as Nongru-700 #, farming breast 2201, this dish-60#, emulsifier T-60(common name:; Among wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, the TERSPERSE 2500 one or more; In thickener such as xanthans, polyvinyl alcohol, the bentonite one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; Defoamer such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more; Water is deionized water.
To granule, spendable auxiliary agent has: carrier such as clay, kaolin, talcum, calcium carbonate, diatomite, corn starch, alumina silicate etc.; In dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In adhesive such as polyvinyl alcohol, dextrin, the polyvinylpyrrolidone one or more.
Component of the present invention is reasonable, and treatment adds protective effect, and bactericidal effect is good, and drug cost is low, and its active and bactericidal effect is not the simple superposition of each composition activity, but significant synergistic effect is arranged, and is good to crop safety, meets the security requirement of pesticidal preparations.The present invention has the better prevention effect to rice blast.
Embodiment
In order to prevent and treat the rice blast in the agricultural production, the inventor has carried out mutual composite synergy research with alkene oxime amine and different metsulfovax, ring propionyl bacterium amine, Rabcide, Tebufloquin, according to medicament mechanism of action difference, adopt pot-culture method and mycelial growth rate method to carry out toxicity test respectively.
Pot-culture method:
Alkene oxime amine and different metsulfovax or ring propionyl bacterium amine this method of employing that is mixed.Being wild sensitive rice Pyricularia oryzae Pyricularia oryzae Cav. bacterial strain for the examination germ, is paddy rice sense rice blast kind for studying thing, and every basin sowing is 20 after the vernalization, selects 10 strains, 3 leaves, the 1 heart stage paddy rice seedling of growing way unanimity wherein standby.To test with pathogen and cultivate at the suitable culture base, behind the spore to be generated, wash spore with sterile water, and with 2 layers～4 layers filtered through gauze, make the suspension that concentration is 1 * 105 spore/milliliter, standby.The medicament for preparing is diluted with water to 1mg/L, 2mg/L, 4mg/L, 8mg/L, 5 concentration of 16mg/L.Soup is evenly sprayed in the blade face to all wetting, treat behind the soup natural air drying standby.Every processing 1 basin repeats for 4 times, and establishes the processing that only contains solvent and surfactant and do not contain effective composition and make blank.Use the spore suspension spray inoculation, inoculate after 3 days in chemicals treatment.Moving to after the inoculation preserves moisture under (relative moisture keeps the blade face dewfall to be arranged, 25 ℃～26 ℃ of temperature more than 95%) dark condition in the humidistat cultivates 24 h.Under 25 ℃～26 ℃, the condition of 12h alternation of light and darkness (intensity of illumination 20000 Lux), relative moisture 85%～90%, cultivated 7 days then.Treat that the sick leaf rate of blank reaches 50% when above, the incidence of strain blade is put in order in the classification investigation, and classification and statistical method are:
0 grade: whole strain is anosis;
1 grade: brown some scab occur;
3 grades: typical spindle scab occurs, lesion area accounts for whole below 5% of leaf area;
5 grades: typical scab, lesion area account for 6%～25% of whole leaf area;
7 grades: typical scab, lesion area account for 26%～50% of whole leaf area;
9 grades: typical scab, lesion area account for whole more than 50% of leaf area.
Disease index=[Σ (the sick numbers of sheets at different levels * relative level numerical value)/investigate total number of sheets * 9] * 100%
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100
The EC of each medicament is obtained in linear regression analysis between probit value by preventive effect and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
The mycelial growth rate method:
Alkene oxime amine and Rabcide or Tebufloquin are mixed and adopt this method.Subjects is Pyricularia oryzae (Pyriculariagrisea).Former medicine is mixed with the test medicine that needs, and test method is with reference to " the agricultural industry criteria NY/T1156.2-2006 of the People's Republic of China (PRC) ".At first single agent and each Mixed Pharmacy are arranged 5 variable concentrations gradients (0.25 mg/L, 0.5 mg/L, 1 mg/L, 2 mg/L, 4 mg/L).If the clear water contrast repeats 3 times.Adopting the mycelial growth rate method, with cultured pathogen, is the 5mm card punch with diameter under aseptic condition, cuts the bacterium cake from colony edge, with transfer needle the bacterium cake is connected on the culture medium flat plate of different drug concentrations, puts in 26 ℃ of incubators and cultivates 72h; Check colony diameter, calculate the percentage that each chemicals treatment suppresses mycelial growth, the EC of each medicament is obtained in the linear regression analysis between the probit value by inhibiting rate and the logarithm value of series concentration
50Value with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, is estimated reagent agent to the activity of germ with this.
The co-toxicity coefficient of complex preparation (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Toxicity Determination result shows: a kind of among alkene oxime amine and different metsulfovax, ring propionyl bacterium amine, Rabcide, the Tebufloquin is that 1:20～20:1 uses with rice blast fungus is had virulence preferably with the weight ratio, and significant synergistic effect is all arranged.
Below in conjunction with FORMULATION EXAMPLE and biological Examples content of the present invention is described further.
FORMULATION EXAMPLE 1
Take by weighing 6% alkene oxime amine, 60% different metsulfovax, 4% Morwet D-425(alkyl naphthalene sulfonic acid condensation polymer sodium salt, Akzo Nobel N.V. produces), 3% dispersing agent NNO, 2% Nekal BX, 2% K-12(lauryl sodium sulfate), 2% corn starch, 2% sucrose, kaolin add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, the different metsulfovax water dispersible granules of 66% alkene oxime amine is produced in the pulverizing of ultra micro air-flow, mixing, granulation step.
FORMULATION EXAMPLE 2
Take by weighing 25% alkene oxime amine, 25% ring propionyl bacterium amine, 4% TERSPERSE 2700,2% dispersing agent NNO, 2% Nekal BX (nekal), 2%K-12,3% corn starch, 5% ammonium sulfate, attapulgite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, 50% alkene oxime amine ring propionyl bacterium amine water dispersible granules is produced in the pulverizing of ultra micro air-flow, mixing, granulation step.
FORMULATION EXAMPLE 3
Take by weighing 15% alkene oxime amine, 75% Rabcide, 1% TERSPERSE 2700,1% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 1% Nekal BX, 1%K-12,1% carboxymethyl cellulose, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, 90% alkene oxime amine Rabcide water dispersible granules is produced in the pulverizing of ultra micro air-flow, mixing, granulation step.
FORMULATION EXAMPLE 4
Take by weighing 50% alkene oxime amine, 2.5%Tebufloquin, 3% TERSPERSE 2700,3% dispersing agent NNO, 2% Nekal BX, 2%K-12,1% carboxymethyl cellulose, 5% urea, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule is namely mixed, 52.5% alkene oxime amine Tebufloquin water dispersible granules is produced in the pulverizing of ultra micro air-flow, mixing, granulation step.
FORMULATION EXAMPLE 5
Take by weighing 3% alkene oxime amine, 60% different metsulfovax, 5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials is through mixing, and air-flow makes the different metsulfovax wetting powder of 63% alkene oxime amine after pulverizing.
FORMULATION EXAMPLE 6
Take by weighing 5% alkene oxime amine, 70% ring propionyl bacterium amine, 4% calcium lignosulfonate, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2% Nekal BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate add to 100% weight portion.Above-mentioned raw materials is through mixing, and air-flow makes 75% alkene oxime amine ring propionyl bacterium amine wetting powder after pulverizing.
FORMULATION EXAMPLE 7
Take by weighing 15% alkene oxime amine, 30% Rabcide, 2% calcium lignosulfonate, 2% dispersing agent NNO, 1% Nekal BX, 1%K-12, attapulgite and add to 100% weight portion.Above-mentioned raw materials is through mixing, and air-flow makes 45% alkene oxime amine Rabcide wetting powder after pulverizing.
FORMULATION EXAMPLE 8
Take by weighing 50% alkene oxime amine, 5%Tebufloquin, 4% calcium lignosulfonate, 4% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% White Carbon black, attapulgite and add to 100% weight portion.Above-mentioned raw materials is through mixing, and air-flow makes 55% alkene oxime amine Tebufloquin wetting powder after pulverizing.
FORMULATION EXAMPLE 9
Taking by weighing 6% alkene oxime amine, 30% different metsulfovax, 4%TERSPERSE 4894(U.S. Huntsman Corporation produces), 1.5%TERSPERSE 2500(U.S. Huntsman Corporation produces), 2%TERSPERSE 2020(U.S. Huntsman Corporation produces), 1% aluminium-magnesium silicate, 0.2% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces), deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making the different metsulfovax suspending agent of 36% alkene oxime amine behind the sand mill sand milling.
FORMULATION EXAMPLE 10
Take by weighing 7% alkene oxime amine, 28% ring propionyl bacterium amine, 5%TERSPERSE 4894,2%TERSPERSE 2500,3%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 35% alkene oxime amine ring propionyl bacterium amine suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 11
Take by weighing 30% alkene oxime amine, 10% Rabcide, 2%TERSPERSE 2020,2% this dish-60#, 2% Tween-60 #, 1%TERSPERSE 2500,0.5% white carbon, 0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 40% alkene oxime amine Rabcide suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 12
Take by weighing 20% alkene oxime amine, 10%Tebufloquin, 1%TERSPERSE 2020,3% agricultural newborn 1601#, 2% agricultural newborn 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 30% alkene oxime amine Tebufloquin suspending agent behind the sand mill sand milling.
FORMULATION EXAMPLE 13
Take by weighing 20% alkene oxime amine, 5% different metsulfovax, 1%TERSPERSE 2700,1%TERSPERSE 2500,3% TERSPERSE 4894,5.0% polyvinylpyrrolidone, 0.2% xanthans, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making the different metsulfovax suspension seed-coating agent of 25% alkene oxime amine behind the sand mill sand milling.
FORMULATION EXAMPLE 14
Take by weighing 8% alkene oxime amine, 24% ring propionyl bacterium amine, 3%TERSPERSE 4894,2%TERSPERSE 2500,1%TERSPERSE 2020,4.0% hydroxypropyl methylcellulose, 0.5% bentonite, 5% ethylene glycol, 0.3% Sodium Benzoate, 0.5% silicone defoaming agent deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 32% alkene oxime amine ring propionyl bacterium amine suspension seed-coating agent behind the sand mill sand milling.
FORMULATION EXAMPLE 15
Take by weighing 6% alkene oxime amine, 2% Rabcide, 1%TERSPERSE 2700,1%TERSPERSE 2500,3% TERSPERSE 4894,5.0% polyvinylpyrrolidone, 0.2% xanthans, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 8% alkene oxime amine Rabcide suspension seed-coating agent behind the sand mill sand milling.
FORMULATION EXAMPLE 16
Take by weighing 2% alkene oxime amine, 3%Tebufloquin, 3%TERSPERSE 4894,2%TERSPERSE 2500,1%TERSPERSE 2020,6.0% hydroxypropyl methylcellulose, 0.5% bentonite, 5% ethylene glycol, 0.3% Sodium Benzoate, 0.5% silicone defoaming agent deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 5% alkene oxime amine Tebufloquin suspension seed-coating agent behind the sand mill sand milling.
FORMULATION EXAMPLE 17
Take by weighing 5% alkene oxime amine, 10% different metsulfovax, 3% sodium lignin sulfonate, 2% neopelex, 3% polyvinyl alcohol, kaolin and add to 100% weight portion.Mentioned component is added water mediate, use and pinch out comminutor and pinch out and is shaped, afterwards with the particle fluid-bed drying, the adjustment particle size makes the different metsulfovax granule of 15% alkene oxime amine.
FORMULATION EXAMPLE 18
Take by weighing 7.5% alkene oxime amine, 7.5% ring propionyl bacterium amine, 2% sodium lignin sulfonate, 3% TERSPERSE 2700,3% polyvinylpyrrolidone, clay and add to 100% weight portion.Above-mentioned raw materials is mediated through mixing and water adding, uses to pinch out comminutor and pinch out and is shaped, afterwards particle is used fluid-bed drying, and the adjustment particle size makes 15% alkene oxime amine ring propionyl bacterium amine granule.
FORMULATION EXAMPLE 19
Take by weighing 7% alkene oxime amine, 14% Rabcide, 2% neopelex, 3% dispersing agent NNO, 3% polyvinylpyrrolidone, kaolin and add to 100% weight portion.Above-mentioned raw materials is mediated through mixing and water adding, uses to pinch out comminutor and pinch out and is shaped, afterwards particle is used fluid-bed drying, and the adjustment particle size makes 21% alkene oxime amine ring propionyl bacterium amine granule.
FORMULATION EXAMPLE 20
Take by weighing 15% alkene oxime amine, 5% Tebufloquin, 3% lauryl sodium sulfate, 3% dispersing agent NNO, 4% dextrin, diatomite and add to 100% weight portion.Above-mentioned raw materials is mediated through mixing and water adding, uses to pinch out comminutor and pinch out and is shaped, afterwards particle is used fluid-bed drying, and the adjustment particle size makes 20% alkene oxime amine Tebufloquin granule.
Biological Examples 1: control rice blast field trial (spraying)
Carried out the different metsulfovax suspending agent of FORMULATION EXAMPLE 9(36% alkene oxime amine at Shaanxi Province's Hanzhong City in 2011), FORMULATION EXAMPLE 2(50% alkene oxime amine ring propionyl bacterium amine water dispersible granules), FORMULATION EXAMPLE 7(45% alkene oxime amine Rabcide wetting powder), FORMULATION EXAMPLE 12(30% alkene oxime amine Tebufloquin suspending agent) control rice blast field trial, verify that this medicament is to the control efficiency of rice blast, effective dose and to the safety of paddy rice.Trial crops is paddy rice, and controlling object is rice blast (Pyricularia oryzae Cav.).Test is located at the Hanzhong City Hantai District, and test medicine and dosage see table 5 for details.Other establishes blank, and every processing 4 times repeats, every residential quarter area 30 ㎡, and totally 72 residential quarters, district's group is arranged at random.Adopt conventional spray-on process, mu dispenser liquid 50kg evenly sprays the paddy rice complete stool.Altogether dispenser is 2 times, paddy rice booting latter stage and each dispenser of full heading time 1 time.
Investigation and statistical method:
Investigation in 14 days after the 2nd dispenser, investigation method is 5 samplings in every residential quarter, every some investigation 50 fringes, grade scale is as follows:
0 grade: anosis;
1 grade: every fringe loss is (morbidity of indivedual branch stalk) below 5%;
3 grades: every fringe loss 6%-20% (branch stalk morbidity about 1/3);
5 grades: every fringe loss 21%-50% (fringe neck or main shaft morbidity, grain half is flat);
7 grades: every fringe loss 51%-70% (morbidity of fringe neck, most of shrivelled kernel);
9 grades: every fringe loss 71%-100% (morbidity of fringe neck causes dead ears).
Refer to calculate preventive effect according to disease.Behind each spray medicine behind the 1st day and the medicine some days, each handled influence to paddy rice to observe medicament.
Disease index=[Σ (sick spike numbers at different levels * relative level numerical value)/investigate total spike number * 9] * 100%
Control efficiency (%)=[(contrast disease index-processing disease index)/contrast disease index] * 100.
Field test results shows: 1800 times of the different metsulfovax suspending agents of 36% alkene oxime amine, 2000 times, 2200 times, 4000 times of 50% alkene oxime amine ring propionyl bacterium amine water dispersible granules, 4200 times, 4400 times, 2200 times of 45% alkene oxime amine Rabcide wetting powders, 2400 times, 2600 times, 3200 times of 30% alkene oxime amine Tebufloquin suspending agents, 3400 times, 3600 times, rice blast is had than remarkable prevention effect, obviously be better than 1000 times of 10% alkene oxime amine missible oil, 1000 times of 30% different metsulfovax suspending agents, 1000 times of 20% ring propionyl bacterium amine amine suspending agents, 1000 times of 50% Rabcide wetting powders, 1000 times of control efficiency to rice blast of 10%Tebufloquin suspending agent.
To the security survey of paddy rice, to observe in some days behind the 1st day and the medicine behind the spray medicine, each test is handled not to be had the poisoning phenomenon to paddy rice and takes place.
After result of the test shows that alkene oxime amine and different metsulfovax, ring propionyl bacterium amine, Rabcide, Tebufloquin are mixed, obviously improved the control efficiency to rice blast, having reduced dosage and drug cost, to paddy growth safety, is the desirable medicament of control rice blast.
Biological Examples 2: control rice blast field trial (seed dressing)
Carried out the different metsulfovax suspension seed-coating agent of FORMULATION EXAMPLE 13(25% alkene oxime amine at Shaanxi Province's Ankang City Hanbin District in 2011), FORMULATION EXAMPLE 14(32% alkene oxime amine ring propionyl bacterium amine suspension seed-coating agent), FORMULATION EXAMPLE 15(8% alkene oxime amine Rabcide suspension seed-coating agent), FORMULATION EXAMPLE 16(5% alkene oxime amine Tebufloquin suspension seed-coating agent) control rice blast field trial.Test medicine and dosage see table 6 for details.Other establishes the clear water blank, and every processing repeats for 4 times, area residential quarter, residential quarter area 20 ㎡, and district's group is arranged at random.Each chemicals treatment is calculated dosing and is converted the water yield in the ratio of 1.6 hydrargyrum oxydatum crudum liquid processing double centner seed.Handle the back sowing in rice paddy seed.
Investigation and statistical method are investigated 2 times altogether, and respectively at rice seedling and the investigation of fringe phase, 5 points are investigated in every residential quarter, every 20 strains (fringe), and diseased plant (fringe) rate of residential quarter rice blast is respectively handled in investigation, calculates preventive effect.Observe each processing of medicament to the influence of paddy rice at each crucial growing stage of paddy rice.
Diseased plant rate (%)=(the morbidity strain number/total strain number of investigation) * 100
Control efficiency (%)=[(check plot diseased plant rate-treatment region diseased plant rate)/check plot diseased plant rate] * 100.
Field test results shows, the different metsulfovax suspension seed-coating agent of 25% alkene oxime amine, 32% alkene oxime amine ring propionyl bacterium amine suspension seed-coating agent, 8% alkene oxime amine Rabcide suspension seed-coating agent, 5% alkene oxime amine Tebufloquin suspension seed-coating agent are pressed dosage Rice seeds treated in the table 6 respectively to rice blast, rice seedling and the rice blast of fringe phase all there is good preventive effect, especially it is remarkable to control seedling stage rice blast effect, to the control of also need spraying of later stage rice blast.The preventive effect of these several mixture preparations obviously is better than 5 kinds of single agent such as 10% alkene oxime amine suspension seed-coating agent, 10% different metsulfovax suspension seed-coating agent to the preventive effect of rice blast.
To the security survey of paddy rice, handle the rice seedling rate and be higher than blank about 2%, growing also is better than blank, shows that medicament is to paddy growth safety, no poisoning.
After result of the test shows that alkene oxime amine and different metsulfovax, ring propionyl bacterium amine, Rabcide, Tebufloquin are mixed, by the chemicals treatment rice paddy seed, obviously improved the control efficiency to rice blast, dosage and drug cost have been reduced, to paddy growth safety, it is the desirable medicament of control rice blast.
Biological Examples 3: control rice blast field trial (spreading fertilizer over the fields granule)
Carried out the different metsulfovax granule of FORMULATION EXAMPLE 17(15% alkene oxime amine in 2011 in Ankang City Hanyin County, Shaanxi Province), FORMULATION EXAMPLE 18(15% alkene oxime amine ring propionyl bacterium amine particle), FORMULATION EXAMPLE 19(21% alkene oxime amine Rabcide granule), FORMULATION EXAMPLE 20(20% alkene oxime amine Tebuf loquin granule) control rice blast field trial.Test medicine and dosage see table 7 for details.Other establishes blank, and every processing repeats for 4 times, area residential quarter, residential quarter area 20 ㎡, and the ridge is built in the minizone, single single the filling, district's group is arranged at random.Each medicament is mixed fine sand 10Kg by a design mu consumption and is spread fertilizer over the fields, in rice transplanting phase and each dispenser in booting stage once.
Investigation and statistical method are investigated 2 times altogether, and respectively at investigation in 21 days after each dispenser, 5 points are investigated in every residential quarter, every 20 strains (fringe), and diseased plant (fringe) rate of residential quarter rice blast is respectively handled in investigation, calculates preventive effect.Observe each processing of medicament to the influence of paddy rice at each crucial growing stage of paddy rice.
Diseased plant rate (%)=(the morbidity strain number/total strain number of investigation) * 100
Control efficiency (%)=[(check plot diseased plant rate-treatment region diseased plant rate)/check plot diseased plant rate] * 100.
Field test results shows, the different metsulfovax granule of 15% alkene oxime amine 500g/ mu, 15% alkene oxime amine ring propionyl bacterium amine granule 600g/ mu, 21% alkene oxime amine Rabcide granule 500g/ mu, 20% alkene oxime amine Tebufloquin granule 400g/ mu, respectively spread fertilizer over the fields once in rice transplanting phase and booting stage, rice seedling and the rice blast of fringe phase all there are preventive effect preferably, obviously are better than 5 kinds of single agent such as 10% alkene oxime amine granule, 10% different metsulfovax granule to the preventive effect (table 7) of rice blast.
To the security survey of paddy rice, each test is handled paddy growth safety, no poisoning.
Result of the test is made granule and is spread fertilizer over the fields control rice blast after showing that alkene oxime amine and different metsulfovax, ring propionyl bacterium amine, Rabcide, Tebufloquin are mixed, and drug effect is obvious, dispenser is easy, saving manpower, to paddy growth safety, is the desirable medicament of control rice blast.
In sum, composition of the present invention is to adopt two kinds of active component compound schemes, its activity and bactericidal effect are not the simple superposition of each composition activity, compare with existing unitary agent, except having significant bactericidal effect, and significant synergistic effect is arranged, and good to crop safety, meet the security requirement of pesticidal preparations.
Claims (8)
1. a bactericidal composition that contains alkene oxime amine is characterized in that the composition active component is alkene oxime amine and Rabcide, and the weight ratio of alkene oxime amine and Rabcide is 1:20～20:1.
2. according to the described bactericidal composition that contains alkene oxime amine of claim 1, it is characterized in that: the weight ratio of alkene oxime amine and Rabcide is 1:10～10:1.
3. according to the described bactericidal composition that contains alkene oxime amine of claim 2, it is characterized in that: the weight ratio of alkene oxime amine and Rabcide is 1:5～5:1.
4. according to the described bactericidal composition that contains alkene oxime amine of claim 3, it is characterized in that: the weight ratio of alkene oxime amine and Rabcide is 1:2～2:1.
5. according to the described bactericidal composition that contains alkene oxime amine of claim 1, it is characterized in that: the cumulant of alkene oxime amine and Rabcide is 5%～90% of described composition total weight.
6. according to the described bactericidal composition that contains alkene oxime amine of claim 5, it is characterized in that: the cumulant of alkene oxime amine and Rabcide is 8%～75% of described composition total weight.
7. according to the described bactericidal composition that contains alkene oxime amine of claim 1, it is characterized in that: described combination dosage form is water dispersible granules, wetting powder, suspending agent, suspension seed-coating agent, granule.
8. the described application of bactericidal composition on the control rice blast that contains alkene oxime amine of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310233199.8A CN103271032B (en) | 2012-05-31 | 2012-05-31 | Bactericide composition containing SYP-1620 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310233199.8A CN103271032B (en) | 2012-05-31 | 2012-05-31 | Bactericide composition containing SYP-1620 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210173315.7A Division CN102696632B (en) | 2012-05-31 | 2012-05-31 | Bactericidal composition containing SYP-1620 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103271032A true CN103271032A (en) | 2013-09-04 |
| CN103271032B CN103271032B (en) | 2014-04-09 |
Family
ID=49053279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310233199.8A Active CN103271032B (en) | 2012-05-31 | 2012-05-31 | Bactericide composition containing SYP-1620 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103271032B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108739813A (en) * | 2018-08-14 | 2018-11-06 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of bactericidal composition and its application containing Rabcide and pefurazoate |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1309897A (en) * | 2000-02-24 | 2001-08-29 | 沈阳化工研究院 | Unsaturated oximino ether bactericide |
| US20120027741A1 (en) * | 2009-02-19 | 2012-02-02 | Pierre-Yves Coqueron | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance |
-
2012
- 2012-05-31 CN CN201310233199.8A patent/CN103271032B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1309897A (en) * | 2000-02-24 | 2001-08-29 | 沈阳化工研究院 | Unsaturated oximino ether bactericide |
| US20120027741A1 (en) * | 2009-02-19 | 2012-02-02 | Pierre-Yves Coqueron | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108739813A (en) * | 2018-08-14 | 2018-11-06 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of bactericidal composition and its application containing Rabcide and pefurazoate |
| CN108739813B (en) * | 2018-08-14 | 2021-01-22 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing tetrachlorophthalide and pefurazoate and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103271032B (en) | 2014-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103749454B (en) | The bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and acid amide fungicides | |
| CN102715156B (en) | Sterilization composition containing js399-19 | |
| CN102626099B (en) | Bactericidal composition containing cupric nonyl phenolsulfonate and methoxy-acrylate bactericide | |
| CN102696646B (en) | Sterilizing composite containing captan | |
| CN104839180B (en) | Fungicide composition and application thereof | |
| CN103210925B (en) | Sterilization composition containing pyrazole naphthalene bacteria amine | |
| CN102640761B (en) | Sterilization composition containing SYP-1620 and oomycete prevention and treatment sterilization agents | |
| CN102388888B (en) | Sterilization composite containing coumoxystrobin and fludioxonil | |
| CN102428930B (en) | Bactericidal composition containing JS399-19 | |
| CN103947640B (en) | A kind of bactericidal composition preventing and treating crops soil-borne disease | |
| CN103975935B (en) | A kind of bactericidal composition preventing and treating crops soil-borne disease | |
| CN103749479B (en) | The bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and acid amide fungicides | |
| CN102657198A (en) | Sterilization and production-increase composition containing phethalanilic acid | |
| CN102302005B (en) | Application of JS399-19 (2-cyano-3-amino-3-phenylacrylic acetate) in preventing and controlling wheat take-all diease | |
| CN102696632B (en) | Bactericidal composition containing SYP-1620 | |
| CN103271032B (en) | Bactericide composition containing SYP-1620 | |
| CN103271076B (en) | Bactericide composition containing SYP-1620 | |
| CN105076212B (en) | A kind of bactericidal composition containing bacillus subtilis and 2-cyano-3-amino-3-phenylancryic acetate | |
| CN102626097A (en) | Bactericidal composition containing famoxadone | |
| CN102972402B (en) | Kasugamycin-containing pesticide composition | |
| CN102669164A (en) | Syp-1620 containing sterilization composition | |
| CN103271036B (en) | Sterilization composition containing SYP-1620 | |
| CN103210936B (en) | Bactericide and purpose thereof | |
| CN102224824B (en) | Sterilization composition containing kresoxim-methyl and iprodione | |
| CN102630687B (en) | Bactericidal composition containing fenamistrobin and metiram |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |