CN103270955B - Cage - Google Patents
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- CN103270955B CN103270955B CN201310213687.2A CN201310213687A CN103270955B CN 103270955 B CN103270955 B CN 103270955B CN 201310213687 A CN201310213687 A CN 201310213687A CN 103270955 B CN103270955 B CN 103270955B
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Abstract
The invention relates to a cage comprising a cavity, a transparent top cover used for closing one end of the cavity and a bottom plate used for closing the other end of the cavity. The cavity comprises a breathing side wall and transparent side walls. One side of the breathing side wall is connected with one transparent side wall through hinges. A lock catch is arranged on one side, opposite to the hinges, of the breathing side wall; and one side, opposite to the hinges, of the breathing side wall is fastened on the corresponding transparent side wall through the lock catch. Optical fiber rotary joints are arranged on the transparent top cover and used for connecting optical fibers inside and outside the cavity. The cage can be used for feeding animals subjected to photosensitive genetic modification as well as light control experiments.
Description
Technical field
The present invention relates to animal feeding technical field, particularly relate to a kind of can being used for through the improved animal feeding of photosensitizing effect and the cage tool carrying out light regulation and control experiment.
Background technology
" light genetics " technology is a kind of brand-new biotechnology incorporating genetic engineering, electrophysiology, optics and electronic engineering technology, its general principle be photosensitizing effect is imported animal (as, mouse) a certain specific cell subsets in express, then the improved animal of laser deburring regular menstruation during early pregnancy photosensitizing effect is used, to study by the change of the animal nerve network function connection of the improved animal of photosensitizing effect under different stimulated parameter and the relation with relevant behaviouristics output; The effect such as various kinds of drug, cell factor can also be coordinated simultaneously, be further used for the research and development of clinical medicine.
To when the improved animal of photosensitizing effect is studied, the sleeve pipe normally implanted optical fiber at certain position of the head of animal in advance or use for slotting optical fiber or injectable drug, to carry out the researchs such as light regulation and control, drug delivery.And optical fiber or sleeve pipe have certain height, encounter cage for rearing poultry and easily come off.Once optical fiber or sleeve pipe come off, next step experiment just cannot be carried out.
And traditional cage for rearing poultry for letting animals feed there is no the height considering optical fiber or sleeve pipe, when raising the animal with optical fiber or sleeve pipe, easily there is optical fiber or sleeve pipe dropping situations.And traditional breeding cage only has raising function usually, when carrying out light regulation and control experiment to animal, need animal to be transferred in other equipment to carry out, very inconvenient.
Summary of the invention
Based on this, be necessary to provide a kind of cage tool that can be used for carrying out again through the improved animal feeding of photosensitizing effect light regulation and control experiment.
A kind of cage tool, comprises cavity, for closing the transparent cap of described cavity one end and the base plate for closing the described cavity other end;
Described cavity comprises ventilative sidewall and transparent sidewall, described ventilative sidewall side is connected with described transparent sidewall by hinge, the side that described ventilative sidewall is relative with described hinge is provided with snap close, and the side that described ventilative sidewall is relative with described hinge is fastened on described transparent sidewall by described snap close;
Described transparent cap is provided with fiber rotation connector, for connecting the optical fiber in cavity and outside cavity.
Wherein in an embodiment, described ventilative sidewall is provided with food groove and tank away from one end of described transparent cap.
Wherein in an embodiment, described cavity is cuboid or the isosceles ladder bodily form.
Wherein in an embodiment, the number of described transparent sidewall is three, be respectively the first transparent sidewall, the second transparent sidewall and the 3rd transparent sidewall that connect successively, described ventilative sidewall side is connected with described first transparent sidewall by hinge, and the side that described ventilative sidewall is relative with described hinge is fastened on described 3rd transparent sidewall by described snap close;
The number of described base plate is one, described first transparent sidewall and described 3rd transparent sidewall one end away from described transparent cap are equipped with draw-in groove, described base plate is arranged on described cavity by the draw-in groove on described first transparent sidewall and described 3rd transparent sidewall, and described base plate is parallel with described transparent cap.
Wherein in an embodiment, the number of described transparent sidewall is three, be respectively the first transparent sidewall, the second transparent sidewall and the 3rd transparent sidewall that connect successively, described ventilative sidewall side is connected with described first transparent sidewall by hinge, and the side that described ventilative sidewall is relative with described hinge is fastened on described 3rd transparent sidewall by described snap close;
The number of described base plate is two, be respectively the first base plate and the second base plate, described first transparent sidewall is provided with away from one end of described transparent cap the first draw-in groove and the second draw-in groove that are parallel to each other, relatively described first draw-in groove of described second draw-in groove is near described transparent cap, and described 3rd transparent sidewall is provided with the 3rd corresponding with described first draw-in groove and described second draw-in groove respectively draw-in groove and the 4th draw-in groove;
Described first base plate is arranged on described cavity by described first draw-in groove and described 3rd draw-in groove, and described first base plate is parallel with described transparent cap, described second base plate is arranged on described cavity by described second draw-in groove and described 4th draw-in groove, and described second base plate is parallel with described transparent cap.
Wherein in an embodiment, described first base plate is the resin plate with white coating.
Wherein in an embodiment, the number of described fiber rotation connector is one, and described fiber rotation connector is 1 × 1 type or 1 × 2 type.
Wherein in an embodiment, the number of described fiber rotation connector is multiple, wherein, at least there is 1 × 1 type, at least there is 1 × 2 type.
Wherein in an embodiment, described ventilative sidewall is fence structure or network structure.
Above-mentioned cage prodigiosin is used for raising through the improved animal of photosensitizing effect, and transparent cap and transparent sidewall are convenient observes the growing state of animal in cage.Ventilative sidewall side is connected with transparent sidewall by hinge, and the side relative with hinge is provided with snap close, thus makes above-mentioned cage tool have good air permeable effect, and is easy to the feature changing water and food in cavity.In addition, transparent cap due to above-mentioned cage tool is provided with and connects in cavity and the fiber rotation connector of cavity infrared optical fiber, thus make to raise in above-mentioned cavity, and the animal capable that head implants optical fiber or sleeve pipe in advance connects with extraneous lasing light emitter, with research by the change of the animal nerve network function connection of the improved animal of photosensitizing effect under different stimulated parameter and the relation with relevant behaviouristics output, do not need animal to be transferred in other equipment, very convenient and practical.
Accompanying drawing explanation
Fig. 1 is the structural representation of the cage tool in an embodiment;
Fig. 2 is the profile of the cage tool in Fig. 1;
Fig. 3 is the structural representation of the printing opacity sidewall of cage tool in Fig. 1;
Fig. 4 is trajectory diagram freely movable in mouse cage tool in FIG.
Embodiment
For the ease of understanding the present invention, below with reference to relevant drawings, cage tool of the present invention is described more fully.Preferred embodiment of the present invention is given in accompanying drawing.But the present invention can realize in many different forms, is not limited to embodiment described herein.On the contrary, provide the object of these embodiments be make the understanding of disclosure of the present invention more comprehensively thorough.
It should be noted that, when element is called as " being fixed on " another element, directly can there is element placed in the middle in it on another element or also.When an element is considered to " connection " another element, it can be directly connected to another element or may there is centering elements simultaneously.
Unless otherwise defined, all technology used herein and scientific terminology are identical with belonging to the implication that those skilled in the art of the present invention understand usually.The object of term used in the description of the invention herein just in order to describe specific embodiment, is not intended to be restriction the present invention.Term as used herein " and/or " comprise arbitrary and all combinations of one or more relevant Listed Items.
As Figure 1-3, the cage tool 10 in an embodiment, comprises transparent cap 100, cavity 200 and base plate (not shown).In the present embodiment, cage tool 10 is cuboid.
Transparent cap 100 is for one end of closed cavity 200.Transparent cap 100 is provided with fiber rotation connector, for connecting the optical fiber 30 in cage tool 10 and the optical fiber outside cage tool 10.
In the present embodiment, the number of fiber rotation connector is two, is respectively 1 × 1 type fiber rotation connector 110, and 1 × 2 type fiber rotation connector 120.
1 × 1 type fiber rotation connector 110 comprises gland 112 and swivel head 114, and gland 112 is provided with a fiber-optical socket 113, and swivel head 114 is also only provided with a fiber-optical socket 115.In the present embodiment, transparent cap 100 offers the through hole running through transparent cap 100, the gland 112 of 1 × 1 type fiber rotation connector 110 is fixed on fixed head 111, and fixed head 111 is fixed on transparent cap 100, thus make swivel head 114 be suspended in through hole, and then make swivel head 114 can by the direction shown in Fig. 2,360 degree of rotations.Meanwhile, fiber-optical socket 113 is positioned at outside cage tool 10, is connected with the optical fiber (comprising fibre-optical splice) outside cage tool 10 by fiber-optical socket 113.Fiber-optical socket 115 is positioned at cage tool 10, fibre-optical splice 32 is comprised with the optical fiber 30(in cage tool 10 by fiber-optical socket 115) be connected, thus optical fiber 30 energy 360 degree in the cage tool 10 be connected with animal 20 and fiber-optical socket 115 rotates, and then make animal 20 after being connected with optical fiber 30, still can in cage tool 10 freely-movable, thus result when making experimental result and animal in the raw closer to.1 × 1 type fiber rotation connector 110 is generally used for connecting the animal 20 of an only band sleeve pipe 40, for light regulation and control or the administration intervention in one-sided brain district.
1 × 2 type fiber rotation connector 120 comprises gland 122 and swivel head 124, and gland 122 is provided with a fiber-optical socket 123, and swivel head 124 is provided with two fiber-optical sockets 125.Therefore, 1 × 2 type fiber rotation connector 120 can be used for connecting double-jacket tube accessory 50, for light regulation and control or the administration intervention in bilateral cerebral district.In the present embodiment, transparent cap 100 offers the through hole running through transparent cap 100, the gland 122 of 1 × 2 type fiber rotation connector 120 is fixed on fixed head 121, and fixed head 121 is fixed on transparent cap 100, thus swivel head 124 is suspended in through hole.
Be appreciated that in other embodiments, the number of fiber rotation connector also can be one, can be chosen as 1 × 1 type fiber rotation connector 110 or 1 × 2 type fiber rotation connector 120 according to actual needs.The number of fiber rotation connector also can be more than two, can select at least one 1 × 1 type fiber rotation connector 110 according to actual needs, at least one 1 × 2 type fiber rotation connector 120.
Cavity 200 comprises transparent sidewall 210 and ventilative sidewall 220.
In the present embodiment, the number of transparent sidewall 210 is three, is respectively the first transparent sidewall 214 of transparent sidewall 212, second and the 3rd transparent sidewall 216 connected successively.
First transparent sidewall 212 is provided with the first draw-in groove 211 and relative first draw-in groove 211 of the second draw-in groove 213, second draw-in groove 213 that are parallel to each other near transparent cap 100 away from one end of transparent cap 100.3rd transparent sidewall 216 is provided with the 3rd corresponding with the first draw-in groove 211 and the second draw-in groove 213 respectively draw-in groove 215 and the 4th draw-in groove 217.Spacing distance between first draw-in groove 211 and the second draw-in groove 213 is about 5mm.Distance between first draw-in groove 211 and ground can be determined according to the actual requirements.Be appreciated that in other embodiments, cage tool 10 can be isosceles trapezoid body, and now, can control between the first draw-in groove 211 and the second draw-in groove 213 is being about 5mm perpendicular to upper base and the spacing distance on the direction of going to the bottom.
First draw-in groove 211 and the 3rd draw-in groove 215 with the use of, for making the first base plate 310 be arranged in cavity 200 by the first draw-in groove 211 and the 3rd draw-in groove 215, and the first base plate 310 is parallel with transparent cap 100.Second draw-in groove 213 and the 4th draw-in groove 217 with the use of, for making the second base plate 320 be arranged in cavity 200 by the second draw-in groove 213 and the 4th draw-in groove 217, and the second base plate 320 is parallel with transparent cap 100.
In the present embodiment, come for cage tool 10 mounting base by arranging draw-in groove on cavity 200, base plate is flexibly connected with cavity 200, thus selectively according to demand can install the base plate needed, and selectively detaches unwanted base plate.Install or detach base plate process and use the similar process of drawer, simple and practical, the cleaning of also very convenient cage tool 10 simultaneously.First base plate 310 and the second base plate 320 can protrude from draw-in groove, more conveniently like this first base plate 310 and the second base plate 320 are detached from transparent sidewall 210, and obviously, the first base plate 310 and the second base plate 320 also can not protrude from draw-in groove.
In the present embodiment, domesticated animal 20 is that its head is inserted with optical fiber or sleeve pipe through the improved mouse of photosensitizing effect.When letting animals feed 20, usually the second base plate 320 is installed on cavity 200, and lays bedding and padding on the second base plate 320, thus animal 20 is not besmirched by the excreta of self.And the height of cavity 200 can be determined according to concrete raising object.If raise to as if mouse, the height of cavity 200 is preferably 137 ~ 140mm.If raise to as if rat, the height of cavity 200 is preferably 170 ~ 200mm.
When carrying out the experiment of light regulation and control to animal 20, usually the first base plate 310 is installed on cavity 200, and the second base plate 320 is detached cavity 200, now, implant in advance and have the animal of optical fiber or sleeve pipe to be placed on the first base plate 310, and fibre circuit is connected.When carrying out the experiment of light regulation and control, sometimes need the step of carrying out making a video recording or taking pictures, therefore, the material of the first base plate 310 is preferably the opaque resin plate with white coating.
Monitor through the improved mouse of photosensitizing effect when carrying out the experiment of light regulation and control, the event trace in above-mentioned cage tool 10, specifically as shown in Figure 4.Testing result display mouse can be freely movable in cage tool 10, substantially not by any obstruction.
Be appreciated that in other embodiments, cage tool 10 can comprise one piece of fixed base plate, one piece of movable floor, as the second base plate 320.Fixed base plate and cavity 200 one-body molded.Obviously, cage tool 10 also can only include one piece of movable floor, as the second base plate 320.
In the present embodiment, ventilative sidewall 220 side is connected with the first transparent sidewall 212 by hinge 222, and ventilative sidewall 220 opposite side is provided with snap close 224, and ventilative sidewall 220 is connected with the 3rd transparent sidewall 216 by snap close 224.Thus ventilative sidewall 220 is just equivalent to the door of cage tool 10, can open easily and conjunction, and then the replacing of instant food and water.
Ventilative sidewall 220 is provided with food groove and tank (not shown) away from one end of transparent cap 100.In the present embodiment, the position of food groove and tank is all higher than the second draw-in groove 213, and the spacing distance between the first draw-in groove 211 and the second draw-in groove 213 is about 5mm, thus makes animal 20 also can normal life while carrying out light regulation and control experiment.
Material and the structure of ventilative sidewall 220 are preferably wire netting structure.Be appreciated that in other embodiments, material and the structure of ventilative sidewall 220 can also be metallic netted structural, plastic net structure etc.
Above-mentioned cage tool 10 can be used for raising through the improved animal 20 of photosensitizing effect, and transparent cap 100 and transparent sidewall 210 are convenient observes the growing state of animal 20 in cage.Ventilative sidewall 220 side is connected with transparent sidewall 210 by hinge 222, and the side relative with hinge 222 is provided with snap close 224, thus makes above-mentioned cage tool 10 have good air permeable effect, and is easy to the feature changing water and food in cage tool 10.In addition, transparent cap 100 due to above-mentioned cage tool 10 is provided with and connects in cavity 10 and the fiber rotation connector of cavity 10 infrared optical fiber, thus make to raise in above-mentioned cage tool 10, and the animal 20 that head implants optical fiber or sleeve pipe in advance can connect with the lasing light emitter in the external world, with research by the change of the animal nerve network function connection of the improved animal 20 of photosensitizing effect under different stimulated parameter and the relation with relevant behaviouristics output, animal 20 is not needed to be transferred in other equipment, very convenient and practical.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (7)
1. a cage tool, is characterized in that, comprises cavity, for closing the transparent cap of described cavity one end and the base plate for closing the described cavity other end;
Described cavity comprises ventilative sidewall and transparent sidewall, described ventilative sidewall side is connected with described transparent sidewall by hinge, the side that described ventilative sidewall is relative with described hinge is provided with snap close, and the side that described ventilative sidewall is relative with described hinge is fastened on described transparent sidewall by described snap close;
Described transparent cap is provided with fiber rotation connector, for connecting the optical fiber in cavity and outside cavity;
The number of described transparent sidewall is three, be respectively the first transparent sidewall, the second transparent sidewall and the 3rd transparent sidewall that connect successively, described ventilative sidewall side is connected with described first transparent sidewall by hinge, and the side that described ventilative sidewall is relative with described hinge is fastened on described 3rd transparent sidewall by described snap close;
The number of described base plate is two, be respectively the first base plate and the second base plate, described first transparent sidewall is provided with away from one end of described transparent cap the first draw-in groove and the second draw-in groove that are parallel to each other, relatively described first draw-in groove of described second draw-in groove is near described transparent cap, and described 3rd transparent sidewall is provided with the 3rd corresponding with described first draw-in groove and described second draw-in groove respectively draw-in groove and the 4th draw-in groove;
Described first base plate is arranged on described cavity by described first draw-in groove and described 3rd draw-in groove, and described first base plate is parallel with described transparent cap, described second base plate is arranged on described cavity by described second draw-in groove and described 4th draw-in groove, and described second base plate is parallel with described transparent cap; Described first base plate is connected with described chamber activities respectively with described second base plate, described cavity, described transparent cap and described second base plate coordinate and are used for raising through the improved animal of photosensitizing effect, and described cavity, described transparent cap and described first base plate coordinate and be used for carrying out light regulation and control experiment.
2. cage tool according to claim 1, is characterized in that, described ventilative sidewall is provided with food groove and tank away from one end of described transparent cap.
3. cage tool according to claim 1, is characterized in that, described cavity is cuboid or the isosceles ladder bodily form.
4. cage tool according to claim 1, is characterized in that, described first base plate is the resin plate with white coating.
5. the cage tool according to any one of claim 1-4, is characterized in that, the number of described fiber rotation connector is one, and described fiber rotation connector is 1 × 1 type or 1 × 2 type.
6. the cage tool according to any one of claim 1-4, is characterized in that, the number of described fiber rotation connector is multiple, wherein, at least there is 1 × 1 type, at least there is 1 × 2 type.
7. the cage tool according to any one of claim 1-4, is characterized in that, described ventilative sidewall is fence structure or network structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310213687.2A CN103270955B (en) | 2013-05-31 | 2013-05-31 | Cage |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310213687.2A CN103270955B (en) | 2013-05-31 | 2013-05-31 | Cage |
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| Publication Number | Publication Date |
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| CN103270955A CN103270955A (en) | 2013-09-04 |
| CN103270955B true CN103270955B (en) | 2014-12-24 |
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| CN201310213687.2A Active CN103270955B (en) | 2013-05-31 | 2013-05-31 | Cage |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115399248B (en) | 2022-08-23 | 2024-01-23 | 中国人民解放军空军军医大学 | Comprehensive animal feeding device and method |
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| CN101991406A (en) * | 2010-09-21 | 2011-03-30 | 华中科技大学 | Wear-type microscopy device for imaging brain function of small active animal |
| CN102019040A (en) * | 2010-11-29 | 2011-04-20 | 中国科学院深圳先进技术研究院 | Biofeedback photoelectric therapeutic device |
| CN102283137A (en) * | 2011-08-25 | 2011-12-21 | 中国科学院深圳先进技术研究院 | Animal behaviour testing platform for optogenetics regulation and control |
| CN102827768A (en) * | 2012-08-15 | 2012-12-19 | 华中科技大学 | System for researching of functions of neural circuits and regulation of animal behaviors and activities |
| CN103071244A (en) * | 2013-01-25 | 2013-05-01 | 深圳先进技术研究院 | Wireless remote control photostimulation system for animals |
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2013
- 2013-05-31 CN CN201310213687.2A patent/CN103270955B/en active Active
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| JP2931744B2 (en) * | 1992-10-30 | 1999-08-09 | 財団法人大阪バイオサイエンス研究所 | Method and apparatus for compensating for twist in experimental animal leads, tubes, optical fibers, etc. |
| CN101991406A (en) * | 2010-09-21 | 2011-03-30 | 华中科技大学 | Wear-type microscopy device for imaging brain function of small active animal |
| CN102019040A (en) * | 2010-11-29 | 2011-04-20 | 中国科学院深圳先进技术研究院 | Biofeedback photoelectric therapeutic device |
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