CN103269699A - 包括给予二氢杨梅素的治疗酒精中毒、酒精使用障碍以及酒精滥用的方法 - Google Patents

包括给予二氢杨梅素的治疗酒精中毒、酒精使用障碍以及酒精滥用的方法 Download PDF

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CN103269699A
CN103269699A CN201180048110XA CN201180048110A CN103269699A CN 103269699 A CN103269699 A CN 103269699A CN 201180048110X A CN201180048110X A CN 201180048110XA CN 201180048110 A CN201180048110 A CN 201180048110A CN 103269699 A CN103269699 A CN 103269699A
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etoh
dhm
gaba
ethanol
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静·梁
理查德·W·奥尔森
伊戈尔·斯皮格尔曼
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University of California, San Diego
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University of California, San Diego
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/035—Organic compounds containing oxygen as heteroatom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN201180048110XA 2010-08-24 2011-08-23 包括给予二氢杨梅素的治疗酒精中毒、酒精使用障碍以及酒精滥用的方法 Pending CN103269699A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37652810P 2010-08-24 2010-08-24
US61/376,528 2010-08-24
PCT/US2011/048749 WO2012027326A2 (en) 2010-08-24 2011-08-23 Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin

Publications (1)

Publication Number Publication Date
CN103269699A true CN103269699A (zh) 2013-08-28

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CN201180048110XA Pending CN103269699A (zh) 2010-08-24 2011-08-23 包括给予二氢杨梅素的治疗酒精中毒、酒精使用障碍以及酒精滥用的方法

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US (1) US20130053435A1 (cg-RX-API-DMAC7.html)
EP (1) EP2608786A4 (cg-RX-API-DMAC7.html)
JP (1) JP2013536238A (cg-RX-API-DMAC7.html)
KR (1) KR20130098347A (cg-RX-API-DMAC7.html)
CN (1) CN103269699A (cg-RX-API-DMAC7.html)
AU (1) AU2011293556A1 (cg-RX-API-DMAC7.html)
BR (1) BR112013003946A2 (cg-RX-API-DMAC7.html)
CA (1) CA2808680A1 (cg-RX-API-DMAC7.html)
CL (1) CL2013000518A1 (cg-RX-API-DMAC7.html)
EA (1) EA201390217A1 (cg-RX-API-DMAC7.html)
MX (1) MX2013002162A (cg-RX-API-DMAC7.html)
PH (1) PH12013500293A1 (cg-RX-API-DMAC7.html)
SG (1) SG187771A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012027326A2 (cg-RX-API-DMAC7.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108567772A (zh) * 2018-07-24 2018-09-25 广西师范大学 二氢杨梅素的新用途
CN112546014A (zh) * 2020-12-15 2021-03-26 铜仁职业技术学院 一种中药解酒护肝泡腾片及其制备方法
CN112601524A (zh) * 2018-04-06 2021-04-02 奥维德医疗公司 加波沙朵在治疗物质使用障碍中的用途
CN113842461A (zh) * 2021-11-04 2021-12-28 杭州诺莘科技有限责任公司 用于缓解、治疗酒精中毒、酒后不适的gabaa受体结合物、组合物及其应用

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014007853A1 (en) * 2012-07-03 2014-01-09 The Regents Of The University Of California Dihydromyricetin for the treatment of diseases and disorders of the glutamatergic system
CN103772338A (zh) * 2014-01-10 2014-05-07 吉首大学 真空脉动式制备二氢杨梅素的方法
EP3876926A1 (de) * 2018-11-05 2021-09-15 Evanium Healthcare GmbH Alkohol-antidot
US20200147032A1 (en) 2018-11-14 2020-05-14 Robert K. Prud'homme Dihydromyricetin hot melt extrusion formulations and methods for forming them
TW202110437A (zh) * 2019-05-23 2021-03-16 美商希諾瓦有限責任公司 用於酒精誘發之皮膚潮紅之治療及緩解的組成物及方法
MX2021015457A (es) 2019-06-14 2022-04-06 Univ Princeton Formulaciones de dihidromiricetina y un permeabilizante.
GR1010117B (el) 2020-07-14 2021-11-08 Uni Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε, Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου διυδρομυρισετινης, χολινης και μιας ή περισσοτερων βιταμινων με αντιοξειδωτικη δραση, χρησιμων για τη φυσιολογικη λειτουργια του ηπατος
CN118354770A (zh) * 2021-10-07 2024-07-16 罗特格斯新泽西州立大学 具有gabaa受体活性的类黄酮衍生物及使用方法

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CN1399916A (zh) * 2002-08-30 2003-03-05 张友胜 二氢杨梅树皮素在制备食品、化妆品或药品中的应用
CN101336978A (zh) * 2008-08-12 2009-01-07 西北农林科技大学 一种北枳椇总黄酮的提取方法
CN101336987A (zh) * 2008-08-12 2009-01-07 西北农林科技大学 一种枳椇总黄酮的制备方法

Family Cites Families (1)

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KR20040021927A (ko) * 2002-09-06 2004-03-11 차재영 호깨나무와 홍삼 추출물을 이용한 건강 보조식품프로헤파-알지의 개발

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1399916A (zh) * 2002-08-30 2003-03-05 张友胜 二氢杨梅树皮素在制备食品、化妆品或药品中的应用
CN101336978A (zh) * 2008-08-12 2009-01-07 西北农林科技大学 一种北枳椇总黄酮的提取方法
CN101336987A (zh) * 2008-08-12 2009-01-07 西北农林科技大学 一种枳椇总黄酮的制备方法

Non-Patent Citations (2)

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MASAYUKI YOSHIKAWA, ET AL.: "Bioactive constituents of chinese natural medicines. III.", 《YAKUGAKU ZASSHI》, vol. 117, no. 2, 31 December 1997 (1997-12-31), pages 108 - 118 *
YANSONG ZHANG,ET AL: "Isolation and identification of metabolites from dihydromyricetin", 《MAGNETIC RESONANCE IN CHEMISTRY》, no. 45, 31 December 2007 (2007-12-31), pages 909 - 916 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112601524A (zh) * 2018-04-06 2021-04-02 奥维德医疗公司 加波沙朵在治疗物质使用障碍中的用途
CN108567772A (zh) * 2018-07-24 2018-09-25 广西师范大学 二氢杨梅素的新用途
CN112546014A (zh) * 2020-12-15 2021-03-26 铜仁职业技术学院 一种中药解酒护肝泡腾片及其制备方法
CN112546014B (zh) * 2020-12-15 2023-01-31 铜仁职业技术学院 一种中药解酒护肝泡腾片及其制备方法
CN113842461A (zh) * 2021-11-04 2021-12-28 杭州诺莘科技有限责任公司 用于缓解、治疗酒精中毒、酒后不适的gabaa受体结合物、组合物及其应用
CN113842461B (zh) * 2021-11-04 2023-08-11 杭州诺莘科技有限责任公司 用于缓解、治疗酒精中毒、酒后不适的gabaa受体结合物、组合物及其应用

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BR112013003946A2 (pt) 2016-07-12
MX2013002162A (es) 2013-04-05
PH12013500293A1 (en) 2013-03-25
CA2808680A1 (en) 2012-03-01
KR20130098347A (ko) 2013-09-04
WO2012027326A9 (en) 2012-04-19
EA201390217A1 (ru) 2013-12-30
US20130053435A1 (en) 2013-02-28
EP2608786A2 (en) 2013-07-03
AU2011293556A1 (en) 2013-02-28
SG187771A1 (en) 2013-03-28
JP2013536238A (ja) 2013-09-19
CL2013000518A1 (es) 2013-08-02
WO2012027326A2 (en) 2012-03-01
EP2608786A4 (en) 2013-07-03

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