CN103230431A - Medicine for treating stomach disease and application - Google Patents
Medicine for treating stomach disease and application Download PDFInfo
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- CN103230431A CN103230431A CN201310152584XA CN201310152584A CN103230431A CN 103230431 A CN103230431 A CN 103230431A CN 201310152584X A CN201310152584X A CN 201310152584XA CN 201310152584 A CN201310152584 A CN 201310152584A CN 103230431 A CN103230431 A CN 103230431A
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Abstract
The invention relates to the field of medicine, and in particular relates to a medicine for treating stomach disease and an application. The medicine for treating stomach disease comprises the following components in parts by mass: 310-620 parts of furazolidone, 202-520 parts of chloramphenicol, 105-210 parts of propantheline bromide, 2,000-3,000 parts of licorice powder and 2.01-3.95 parts of vitamin B6. The medicine is used for treating acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis or duodenal ulcer. According to the medicine for treating stomach disease and application provided by the embodiment of the invention, multiple components are combined to realize sterilization and suppression effects so as to protect and maintain the stomach; and the raw materials are rich, the price is low, and the treatment cost is lower. In a process of treating stomach disease, the medicine has the advantages of high cure rate, short cure time, perfect effect, simplicity and convenience in preparation, simple preparation flow of technological medicines and obvious curative effect, is safe to take, and avoids adverse reaction.
Description
Technical field
The present invention relates to field of medicaments, in particular to a kind of medicine and purposes for the treatment of gastropathy.
Background technology
Gastropathy is actually the general designation of many diseases.They have similar symptom, as upper abdomen gastral cavilty portion discomfort, pain, after meal glutted, belch, return acid, even feel sick, vomiting etc.Common gastropathy has the innocent and malignant tumour of acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric calculus, stomach clinically, also has prolapse of gastric mucosa, acute gastric dilatation, pyloric obstruction etc.At present, not following five or six ten kinds of the kinds of known treatment gastroenteropathy, motilium, weisen U, JIANWEI XIAOSHI PIAN etc.These drug price costlinesses do not wait to hundreds of unit from dozens of yuan.These courses of pharmaceuticals are long clinically, and curative effect is not very good, and the doctor often needs to add ancillary drug on prescription, and the patient not only will bear load-bearing burden economically, and also will stand immense pressure mentally.
Summary of the invention
The object of the present invention is to provide a kind of medicine and purposes for the treatment of gastropathy, to solve the above problems.
The embodiment of the invention provides a kind of medicine for the treatment of gastropathy, and its composition comprises: in mass fraction, and furazolidone 310-620 part, chloromycetin 202-520 part, propantheline bromide 105-210 part, Radix Glycyrrhizae powder 2000-3000 part, vitamin B6 2.01-3.95 part.
Preferably, its composition of the medicine of described gastropathy comprises: in mass fraction, and furazolidone 485-500 part, chloromycetin 372-380 part, propantheline bromide 149-152 part, Radix Glycyrrhizae powder 2670-2725 part, vitamin B6 2.92-3.1 part.
Preferably, the medicine of described treatment gastropathy is characterized in that, its composition comprises: in mass fraction, and 500 parts of furazolidone, 380 parts in chloromycetin, 150 parts of propantheline bromides, 2700 parts of Radix Glycyrrhizae powder, 3 parts of vitamin Bies.
Preferably, the medicine of described treatment gastropathy, described furazolidone is from furazolidone.
Preferably, the medicine of described treatment gastropathy, the dosage form of described medicine comprises: tablet.
Preferably, the preparation method of described tablet comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
The mixture of winning is pulverized, mixed to the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
Described first mixture is pressed into tablet by powder compressing machine.
Preferably, the dosage form of described medicine comprises: capsule.
Preferably, the preparation method of described capsule comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
With the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6 pulverize, mix second mixture;
Described second mixture is incapsulated or with capsule filling machine described second mixture is manufactured with the capsule ghost and be capsule.
Preferably, the dosage form of described medicine comprises: powder;
The preparation method of described powder comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
With the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6 pulverize, mix powder.
The embodiment of the invention also provides the purposes of the medicine of above-mentioned treatment gastropathy, is used for the treatment of acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis or duodenal ulcer.
A kind of medicine and purposes for the treatment of gastropathy of the above embodiment of the present invention, furazolidone: to the escherichia coli in the intestines and stomach, the special bacillus of dysentery and intestines and stomach pathogenic bacterium thereof are all killed and inhibitory action; Propantheline bromide: effect is better than banthine bromide, stronger periphery cholinolytic, the effect of Antimuscarinic sample are arranged, more weak sympathetic block effect, selectively removing gastrointestinal pancreas gallbladder smooth muscle spasm, suppress glandular secretion, be used for the treatment of stomach, duodenal ulcer, stomach spasm, the stomachache that biliary colic and pancreatitis etc. causes; Chloromycetin is used for the treatment of the infection that is caused by Bacillus typhi, dysentery bacterium, escherichia coli, hemophilus influenza, Brucella, streptococcus pneumoniae etc., and is being better than other antibiotic such as oxytetracycline, penicillin, erythromycin aspect treatment speed and the effect; The present invention is on furazolidone, propantheline bromide, chloromycetin three's cooperation basis, also added Radix Glycyrrhizae powder, Radix Glycyrrhizae powder: QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine, inhibition gastric juice, gastric acid secretion reduce the hexose amine component that gastric acidity increases Gastric Mucosal Cells at the direct sorption gastric acid of gastric, the protection gastric mucosa, make it to be without prejudice, facilitating digestion tract epithelial cell regeneration, stimulate gastric epithelial cells synthetic and discharge the endogenous prostaglandin that the mucosa protective effect is arranged; The present invention has also adopted vitamin B6 to alleviate this symptoms of emesis in order to alleviate patient's vomiting sense.Drug main of the present invention will be applicable to acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis, duodenal ulcer.The medicine for the treatment of gastropathy provided by the invention, a plurality of compositions make up mutually, can finish sterilization and inhibitory action, and stomach is played protection and maintenance effect, abundant raw material, cheap, medical expense is lower.
On the other hand, this medicine is brought into play effect in treatment gastropathy process, the cure rate height, and healing time is short, and curative effect is splendid, and medicine, prepare easyly, and technology medicine making flow process is simple, takes safety, and untoward reaction does not appear in safety of medicine, and is evident in efficacy.
The specific embodiment
Below by specific embodiment the present invention is described in further detail.
Embodiment 1:
A kind of medicine for the treatment of gastropathy, its composition comprises: in mass fraction, furazolidone 310-620 part, chloromycetin 202-520 part, propantheline bromide 105-210 part, Radix Glycyrrhizae powder 2000-3000 part, vitamin B6 2.01-3.95 part.
Furazolidone: to the escherichia coli in the intestines and stomach, the special bacillus of dysentery and intestines and stomach pathogenic bacterium thereof are all killed and inhibitory action;
Propantheline bromide: effect is better than banthine bromide, stronger periphery cholinolytic, the effect of Antimuscarinic sample are arranged, more weak sympathetic block effect, selectively removing gastrointestinal pancreas gallbladder smooth muscle spasm, suppress glandular secretion, be used for the treatment of stomach, duodenal ulcer, stomach spasm, the stomachache that biliary colic and pancreatitis etc. causes.
Chloromycetin is used for the treatment of the infection that is caused by Bacillus typhi, dysentery bacterium, escherichia coli, hemophilus influenza, Brucella, streptococcus pneumoniae etc., and is being better than other antibiotic such as oxytetracycline, penicillin, erythromycin aspect treatment speed and the effect.
Radix Glycyrrhizae powder: QI invigorating invigorating middle warmer; heat-clearing and toxic substances removing; expelling phlegm for arresting cough; relieving spasm to stop pain; the mediation property of medicine, inhibition gastric juice, gastric acid secretion reduce the hexose amine component that gastric acidity increases Gastric Mucosal Cells at the direct sorption gastric acid of gastric; the protection gastric mucosa makes it to be without prejudice, facilitating digestion tract epithelial cell regeneration, stimulates gastric epithelial cells synthetic and discharge the endogenous prostaglandin that the mucosa protective effect is arranged.
The present invention has also adopted vitamin B6 to alleviate this symptoms of emesis in order to alleviate patient's vomiting sense.
The a plurality of compositions of medicine of the present invention make up mutually, can finish sterilization and inhibitory action, and stomach is played protection and maintenance effect.And the composition source is wide, and cost is low.
Drug main of the present invention will be applicable to acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis, duodenal ulcer.
Embodiment 2:
A kind of medicine for the treatment of gastropathy, its composition comprises: furazolidone 310 grams, chloromycetin 202 grams, propantheline bromide 105 grams, Radix Glycyrrhizae powder 2000 grams, vitamin B6 2.01 grams.
The preparation tablet:
Take by weighing furazolidone, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6;
The mixture of winning is pulverized, mixed to the furazolidone, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, the vitamin B6 that take by weighing;
First mixture is pressed into tablet by powder compressing machine.
Embodiment 3:
A kind of medicine for the treatment of gastropathy, its composition comprises: furazolidone 620 grams, chloromycetin 520 grams, propantheline bromide 210 grams, Radix Glycyrrhizae powder 3000 grams, vitamin B6 3.95 grams.
The preparation capsule:
Take by weighing furazolidone, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6;
With the furazolidone that takes by weighing, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6 pulverize, mix second mixture;
With the capsule ghost second mixture is incapsulated the preparation capsule.
Embodiment 4:
A kind of medicine for the treatment of gastropathy, its composition comprises: furazolidone 485 grams, chloromycetin 372 grams, propantheline bromide 149 grams, Radix Glycyrrhizae powder 2670 grams, vitamin B6 2.92 grams.
The preparation capsule:
Take by weighing furazolidone, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6;
With the furazolidone that takes by weighing, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6 pulverize, mix second mixture;
With capsule filling machine second mixture is manufactured and to be capsule.
Embodiment 5:
A kind of medicine for the treatment of gastropathy, its composition comprises: furazolidone 500 grams, chloromycetin 380 grams, propantheline bromide 152 grams, Radix Glycyrrhizae powder 2725 grams, vitamin B6 3.1 grams.
The preparation powder:
Take by weighing furazolidone, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6;
With the furazolidone that takes by weighing, chloromycetin, propantheline bromide, Radix Glycyrrhizae powder, vitamin B6 pulverize, mix powder.
Embodiment 6:
A kind of medicine for the treatment of gastropathy, its composition comprises: 500 parts of furazolidone, 380 parts in chloromycetin, 150 parts of propantheline bromides, 2700 parts of Radix Glycyrrhizae powder, 3 parts of vitamin Bies.
Embodiment 7:
Because therefore main component furazolidone not can replace furazolidone by furazolidone in the furazolidone.
Be 49 to 50 of 0.1g furazolidones (interior Furanzolidon-containing) with specification, specification is three of the vitamin B6 sheets of 10mg, specification is 14 to 15 of the Chloramphenicol Tablets of 0.25g, specification is ten of the propantheline bromide sheets of 15mg, and Radix Glycyrrhizae powder 26g to 27g is pulverized and mixed and evenly is pressed into the agent sheet or makes powder or make powder.
The medicine that it is pointed out that the treatment gastropathy that corresponding the various embodiments described above are produced can be made the agent sheet or make powder or make powder, and it is the fastest in the absorption of the intestines and stomach that medicine is made powder, brings into play the fastest.Make capsule or tablet and do not influence whole curative effect.
Embodiment 8:
The medicine of the treatment gastropathy that corresponding the various embodiments described above are produced is used for the treatment of following any disease: acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis or duodenal ulcer.
Instructions of taking is: medicine was taken three times in one day, took 0.74g to 0.8g at every turn, and medicine is used in taking medicine before meal.
To gastric ulcer, acute gastritis, chronic gastritis, the chronic erosive gastritis therapeutic effect is splendid:
Gastric ulcer mild or moderate patient is taken seven days diseases of medicine obviously alleviate, take medicine basic recovery from illness in 28 days;
Splendid to the acute gastritis curative effect, take that disease obviously alleviates in a couple of days, most of patients is taken and is accepted the doctor behind the medicine and arrange to be careful in one's diet, and 90 percent patient can fully recover, and relapse rate is extremely low;
Chronic atrophic gastritis is had the effect of relief of symptoms, have relief of symptoms, promote intestinal digestion, promote the effect of wriggling ability;
To slight chronic superficial gastritis, more than 90 percent slight chronic superficial gastritis patient take medicine namely rose in six days positive effect, symptom obviously alleviates, and takes the patient and untoward reaction do not occur, takes medicine after 15 days, gastropathy is almost recovered;
To chronic superficial gastritis, the patient who reaches the many decades medical history takes two 28 days courses for the treatment of of medicine of the present invention, can obtain recovery from illness;
To bile reflux gastritis, take medicine rise in seven days positive effect, disease obviously alleviates.Take two 28 days courses for the treatment of of medicine, the gastropathy recovery from illness.
The medicine for the treatment of gastropathy provided by the invention is brought into play effect in treatment gastropathy process, the cure rate height, and healing time is short, curative effect is splendid, and medicine material is abundant, and cheap, medical expense is lower, prepare easy, technology medicine making flow process is simple, takes safety, safety of medicine, untoward reaction does not appear, and evident in efficacy.
Following is to take treatment case of the present invention:
Old XX, the man at the age 52, suffers from chronic superficial gastritis.And being diagnosed as chronic superficial gastritis through the People's Hospital, Fuding City gastroscope, this patient takes the stomach medicine for a long time, and takes medicines such as cimetidine, omeprazole, does not all have healing.The patient changes and takes course for the treatment of of medicine of the present invention.One the course for the treatment of fortnight, every day three times, and in breakfast, lunch and dinner taking medicine before meal usefulness, medication five is the back remission everyday, fully recovers behind the fortnight, to rebound phenomenon not occurring.
Zheng XX, the man at the age 46, suffers from gastric ulcer.And be diagnosed as this patient of gastric ulcer through the People's Hospital, Fuding City gastroscope and take the stomach medicine for a long time, and take medicines such as cimetidine, omeprazole, all there is not healing.The patient changes and takes course for the treatment of of medicine of the present invention.15 days course for the treatment of, every day three times, and in breakfast, lunch and dinner taking medicine before meal usefulness, medication remission after three days, rebound phenomenon does not appear in recovery from illness after 13 days.
Zhao XX, the woman at the age 35, suffers from chronic superficial gastritis.And being diagnosed as chronic superficial gastritis through the People's Hospital, Fuding City gastroscope, this patient takes the stomach medicine for a long time, and takes medicines such as cimetidine, omeprazole, does not all have healing.The patient changes and takes course for the treatment of of medicine of the present invention.One the course for the treatment of fortnight, every day three times, and in breakfast, lunch and dinner taking medicine before meal usefulness, medication remission after three days was fully recovered after the course for the treatment of, rebound phenomenon do not occur.
Open XX, the man, the age 34 suffers from chronic erosive gastritis.And being diagnosed as chronic erosive gastritis through the People's Hospital, Fuding City gastroscope, this patient takes the stomach medicine for a long time, and takes medicines such as cimetidine, omeprazole, does not all have healing.The patient changes and takes two courses for the treatment of of medicine of the present invention.15 days course for the treatment of, every day three times, and in breakfast, lunch and dinner taking medicine before meal usefulness, medication remission after three days was fully recovered after two courses for the treatment of, rebound phenomenon do not occur.
King XX, the man at the age 45, suffers from bile reflux gastritis.And being diagnosed as bile reflux gastritis through the People's Hospital, Fuding City gastroscope, this patient takes the stomach medicine for a long time, and takes medicines such as cimetidine, omeprazole, does not all have healing.The patient changes and takes medicine of the present invention after two courses for the treatment of.15 days course for the treatment of, every day three times, and in breakfast, lunch and dinner taking medicine before meal usefulness, medication remission after three days, rebound phenomenon does not appear in two recoveries from illness course for the treatment of.
Be the preferred embodiments of the present invention only below, be not limited to the present invention, for a person skilled in the art, the present invention can have various changes and variation.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. a medicine for the treatment of gastropathy is characterized in that, its composition comprises: in mass fraction, and furazolidone 310-620 part, chloromycetin 202-520 part, propantheline bromide 105-210 part, Radix Glycyrrhizae powder 2000-3000 part, vitamin B6 2.01-3.95 part.
2. the medicine of gastropathy according to claim 1, it is characterized in that, its composition comprises: in mass fraction, and furazolidone 485-500 part, chloromycetin 372-380 part, propantheline bromide 149-152 part, Radix Glycyrrhizae powder 2670-2725 part, vitamin B6 2.92-3.1 part.
3. the medicine for the treatment of gastropathy according to claim 2 is characterized in that, its composition comprises: in mass fraction, and 500 parts of furazolidone, 380 parts in chloromycetin, 150 parts of propantheline bromides, 2700 parts of Radix Glycyrrhizae powder, 3 parts of vitamin Bies.
4. the medicine for the treatment of gastropathy according to claim 1 is characterized in that, described furazolidone is from furazolidone.
5. according to the medicine of each described treatment gastropathy of claim 1-4, it is characterized in that the dosage form of described medicine comprises: tablet.
6. the medicine for the treatment of gastropathy according to claim 5 is characterized in that, the preparation method of described tablet comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
The mixture of winning is pulverized, mixed to the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
Described first mixture is pressed into tablet by powder compressing machine.
7. according to the medicine of each described treatment gastropathy of claim 1-4, it is characterized in that the dosage form of described medicine comprises: capsule.
8. the medicine for the treatment of gastropathy according to claim 7 is characterized in that, the preparation method of described capsule comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
With the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6 pulverize, mix second mixture;
Described second mixture is incapsulated or with capsule filling machine described second mixture is manufactured with the capsule ghost and be capsule.
9. according to the medicine of each described treatment gastropathy of claim 1-4, it is characterized in that the dosage form of described medicine comprises: powder;
The preparation method of described powder comprises:
Take by weighing described furazolidone, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6;
With the described furazolidone that takes by weighing, described chloromycetin, described propantheline bromide, described Radix Glycyrrhizae powder, described vitamin B6 pulverize, mix powder.
10. the purposes of the medicine of each described treatment gastropathy of claim 1-9 is characterized in that, is used for the treatment of acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis or duodenal ulcer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310152584XA CN103230431A (en) | 2013-04-27 | 2013-04-27 | Medicine for treating stomach disease and application |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310152584XA CN103230431A (en) | 2013-04-27 | 2013-04-27 | Medicine for treating stomach disease and application |
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| CN103230431A true CN103230431A (en) | 2013-08-07 |
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| CN201310152584XA Pending CN103230431A (en) | 2013-04-27 | 2013-04-27 | Medicine for treating stomach disease and application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4341C1 (en) * | 2013-11-21 | 2015-11-30 | Ион МЕРЕУЦЭ | Syrup for the treatment of gastric precancerous conditions |
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|---|---|---|---|---|
| CN1087000A (en) * | 1993-07-05 | 1994-05-25 | 大庆欧达医药临床应用开发研究所 | A kind of compound recipe stomach medicine that cures mainly Peptic Ulcers |
| CN1293956A (en) * | 1999-10-31 | 2001-05-09 | 边庆瑞 | Preccription for treating gastrosis quickly and radically |
| CN1698813A (en) * | 2005-06-07 | 2005-11-23 | 张丽君 | Chinese and western compound medicine for treating stomach disease |
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2013
- 2013-04-27 CN CN201310152584XA patent/CN103230431A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087000A (en) * | 1993-07-05 | 1994-05-25 | 大庆欧达医药临床应用开发研究所 | A kind of compound recipe stomach medicine that cures mainly Peptic Ulcers |
| CN1293956A (en) * | 1999-10-31 | 2001-05-09 | 边庆瑞 | Preccription for treating gastrosis quickly and radically |
| CN1698813A (en) * | 2005-06-07 | 2005-11-23 | 张丽君 | Chinese and western compound medicine for treating stomach disease |
Non-Patent Citations (1)
| Title |
|---|
| 陈红: "甘草药理作用概述", 《海峡药学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4341C1 (en) * | 2013-11-21 | 2015-11-30 | Ион МЕРЕУЦЭ | Syrup for the treatment of gastric precancerous conditions |
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Application publication date: 20130807 |