CN103228310B - 用于药物输送装置的驱动机构和药物输送装置 - Google Patents

用于药物输送装置的驱动机构和药物输送装置 Download PDF

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Publication number
CN103228310B
CN103228310B CN201180057502.2A CN201180057502A CN103228310B CN 103228310 B CN103228310 B CN 103228310B CN 201180057502 A CN201180057502 A CN 201180057502A CN 103228310 B CN103228310 B CN 103228310B
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CN
China
Prior art keywords
lead screw
drive element
relative
lead
drive
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Active
Application number
CN201180057502.2A
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English (en)
Chinese (zh)
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CN103228310A (zh
Inventor
D.A.普鲁姆普特里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
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Sanofi Aventis Deutschland GmbH
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F16H25/2015—Means specially adapted for stopping actuators in the end position; Position sensing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18568—Reciprocating or oscillating to or from alternating rotary
    • Y10T74/18576—Reciprocating or oscillating to or from alternating rotary including screw and nut
    • Y10T74/18688—Limit stop

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Transmission Devices (AREA)
CN201180057502.2A 2010-10-06 2011-10-05 用于药物输送装置的驱动机构和药物输送装置 Active CN103228310B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20100186736 EP2438951A1 (en) 2010-10-06 2010-10-06 Drive mechanism for a drug delivery device and drug delivery device
EP10186736.4 2010-10-06
PCT/EP2011/067418 WO2012045794A1 (en) 2010-10-06 2011-10-05 Drive mechanism for a drug delivery device and drug delivery device

Publications (2)

Publication Number Publication Date
CN103228310A CN103228310A (zh) 2013-07-31
CN103228310B true CN103228310B (zh) 2015-11-25

Family

ID=43607654

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180057502.2A Active CN103228310B (zh) 2010-10-06 2011-10-05 用于药物输送装置的驱动机构和药物输送装置

Country Status (21)

Country Link
US (1) US9072836B2 (enExample)
EP (2) EP2438951A1 (enExample)
JP (1) JP6042339B2 (enExample)
KR (1) KR101880027B1 (enExample)
CN (1) CN103228310B (enExample)
AR (1) AR083300A1 (enExample)
AU (1) AU2011311617B2 (enExample)
BR (1) BR112013006949B1 (enExample)
CA (1) CA2811953C (enExample)
DK (1) DK2624894T3 (enExample)
ES (1) ES2674594T3 (enExample)
HU (1) HUE037970T2 (enExample)
IL (1) IL225364B (enExample)
MX (1) MX339430B (enExample)
NZ (1) NZ609013A (enExample)
PL (1) PL2624894T3 (enExample)
RU (1) RU2577451C2 (enExample)
SG (1) SG188423A1 (enExample)
TR (1) TR201808737T4 (enExample)
TW (1) TWI538706B (enExample)
WO (1) WO2012045794A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013178600A1 (en) * 2012-05-30 2013-12-05 Sanofi-Aventis Deutschland Gmbh Bearing for a piston rod body for a drug delivery device, a piston rod arrangement and a piston rod body
IL267610A (en) * 2019-06-24 2019-10-31 Dali Medical Devices Ltd dose monitoring
EP4180689A1 (en) * 2021-11-12 2023-05-17 Goodrich Actuation Systems SAS Damping device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101184521A (zh) * 2005-05-24 2008-05-21 特克法马许可公司 用于注射装置的螺杆和计量装置
US20090275914A1 (en) * 2008-05-02 2009-11-05 Sanofi-Aventis Deutschland Gmbh Medication Delivery Device
CN101616705A (zh) * 2006-11-17 2009-12-30 塞诺菲-安万特德国有限公司 药物输送设备的给药和驱动机构
EP2201972A1 (en) * 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Fixed dose injection device with resettable drive mechanism

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663602B2 (en) * 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
DE10237258B4 (de) 2002-08-14 2006-09-21 Tecpharma Licensing Ag Injektionsvorrichtung
GB0304823D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
WO2006089734A1 (de) * 2005-02-22 2006-08-31 Tecpharma Licensing Ag Dosiervorrichtung zum einstellen feiner dosierungen
JP4979686B2 (ja) * 2005-04-24 2012-07-18 ノボ・ノルデイスク・エー／エス 注入デバイス
DE102006038101A1 (de) * 2006-08-14 2008-02-21 Tecpharma Licensing Ag Injektionsvorrichtung mit Klauensicherung
EP1923084A1 (en) * 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device
US8647309B2 (en) * 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
UA101498C2 (ru) * 2008-05-02 2013-04-10 Санофі-Авентіс Дойчланд Гмбх Устройство подачи лекарственного средства

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101184521A (zh) * 2005-05-24 2008-05-21 特克法马许可公司 用于注射装置的螺杆和计量装置
CN101616705A (zh) * 2006-11-17 2009-12-30 塞诺菲-安万特德国有限公司 药物输送设备的给药和驱动机构
US20090275914A1 (en) * 2008-05-02 2009-11-05 Sanofi-Aventis Deutschland Gmbh Medication Delivery Device
EP2201972A1 (en) * 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Fixed dose injection device with resettable drive mechanism

Also Published As

Publication number Publication date
JP2013539677A (ja) 2013-10-28
CN103228310A (zh) 2013-07-31
KR20130120476A (ko) 2013-11-04
EP2624894A1 (en) 2013-08-14
MX2013003665A (es) 2013-05-28
DK2624894T3 (en) 2018-06-25
RU2577451C2 (ru) 2016-03-20
MX339430B (es) 2016-05-26
ES2674594T3 (es) 2018-07-02
EP2438951A1 (en) 2012-04-11
TR201808737T4 (tr) 2018-07-23
NZ609013A (en) 2014-06-27
BR112013006949B1 (pt) 2021-01-19
KR101880027B1 (ko) 2018-07-20
IL225364A0 (en) 2013-06-27
EP2624894B1 (en) 2018-03-21
CA2811953A1 (en) 2012-04-12
JP6042339B2 (ja) 2016-12-14
WO2012045794A1 (en) 2012-04-12
US9072836B2 (en) 2015-07-07
TW201231111A (en) 2012-08-01
BR112013006949A2 (pt) 2016-07-26
AR083300A1 (es) 2013-02-13
AU2011311617B2 (en) 2015-01-22
PL2624894T3 (pl) 2018-08-31
SG188423A1 (en) 2013-04-30
AU2011311617A1 (en) 2013-04-11
IL225364B (en) 2018-10-31
HUE037970T2 (hu) 2018-09-28
US20130211343A1 (en) 2013-08-15
RU2013120298A (ru) 2014-11-20
CA2811953C (en) 2018-07-31
TWI538706B (zh) 2016-06-21

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