CN103202480A - Health food with freckle removing and beautifying functions and preparation method of health food - Google Patents
Health food with freckle removing and beautifying functions and preparation method of health food Download PDFInfo
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- CN103202480A CN103202480A CN201310159163XA CN201310159163A CN103202480A CN 103202480 A CN103202480 A CN 103202480A CN 201310159163X A CN201310159163X A CN 201310159163XA CN 201310159163 A CN201310159163 A CN 201310159163A CN 103202480 A CN103202480 A CN 103202480A
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- angelicae sinensis
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Abstract
The invention discloses health food with freckle removing and beautifying functions and a preparation method of the health food. The health food is prepared from salvia miltiorrhiza, safflower, Chinese angelica, dangshen, dahurian angelica root and dextrin. The preparation method comprises the steps of: extracting the salvia miltiorrhiza, safflower, Chinese angelica, dangshen and dahurian angelica root and preparing powder, mixing the powder with defined amount of dextrin, granulating the mixture, metering the granules, filling the granules into capsules and packaging the capsules, thus preparing the health food. The product prepared by the process not only is safe to take and has an obvious health effect but also is low in industrial production cost.
Description
Technical field
The invention belongs to field of health care food, be specifically related to health food of a kind of spot-dispelling and cosmetic functions and preparation method thereof.
Background technology
Removing beverage is that a kind of brown plaque or spot that upward occurs with elimination skin (mainly based on head-face skin) is the skin beauty health-care method of main effect, is applicable to discosmetic dermatosis diseases such as chloasma, freckle, senile plaque expelling, melanose.Discosmetic dermatosis disease is characterized in: sick send out in outside, especially send out the position outside face, neck, four limbs etc. are exposed to, based on the objective sign shape.Influence people's figure beauty.The generation crowd mostly is the adult, owing to the harmful effect to pattern U.S. causes spiritual misery.
The generation of patch, spot, the traditional Chinese medical science think many and kidney essence deficiency or and fire of deficiency type pent-up, deficiency-weakness of spleen-QI, stagnation of liver qi, outer evil invasion and attack, it is flourish in face to cause vital essence not go up, or qi depression to blood stasis, fire are tied to hinder in surface skin and formed; Doctor trained in Western medicine think its inherent pathogenesis many with endocrine disorder, the metabolism imbalance, microcirculation disorder, reasons such as the influence of chemical factors and aging cause pigmentation relevant.Therefore the methods for the treatment of of removing beverage has enriching kidney essence, strengthening the spleen and replenishing qi, dispersing stagnated hepatoqi, dissipating bind fire, the stasis of blood etc. of invigorating blood circulation.And the performance of these methods for the treatment of effects is again by improving function, regulate human endocrine and immunologic function, improve metabolism, increasing cell viability, and is anti-oxidant, improves skin blood circulation etc. and realizes.
Product of the present invention is to be primary raw material with the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica, to aspect conditioning visceras such as liver, spleen, stomaches, reaches the purpose of functions of removing chloasma from interior.The red sage root, safflower, Radix Angelicae Sinensis dispersing stagnated hepatoqi are promoting blood circulation and removing blood stasis in the side, can transfer smooth whole body mechanism of qi, regulate the activity of feelings will, promote the defeated cloth metabolism of blood and body fluid, promote the fortune function of taste; Radix Codonopsis is assisted a ruler in governing a country blood-activating drug and then can be protected taste in the side, but the strengthening the spleen and replenishing qi green blood; The root of Dahurain angelica induces sweat and looses coldly in the side, and dispelling wind is eliminating evil, and speckle induces sweat.
In sum, the primary raw material of selecting for use the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica to fill a prescription for the present invention, capsule through being processed into, three batches of products of pilot scale detect through relevant provincial disease prevention and control center, and safety evaluatio is reported the result: acute oral toxicity test shows that this product belongs to nontoxic level; Three genetic toxicity test results are all negative; 30 days feeding trial results do not see that rat has obvious toxic and side effects.Above result proves that all product of the present invention can use by safety clothes.The result of removing chloasma human feeding trial report proves that also product of the present invention has the health care of removing chloasma.
Summary of the invention
The object of the present invention is to provide health food of a kind of spot-dispelling and cosmetic functions and preparation method thereof.This technology makes product and not only takes safety, has significant health-care efficacy, and industrial production cost is low, and good market development application prospect is arranged.
For achieving the above object, the present invention adopts following technical scheme:
A kind of composition of raw material of health food of spot-dispelling and cosmetic functions and mass fraction: red sage root 15%-17%, safflower 14%-16%, Radix Angelicae Sinensis 14%-16%, Radix Codonopsis 19%-21%, root of Dahurain angelica 17%-19%, dextrin 15%-17%.
The method for preparing the health food of aforesaid spot-dispelling and cosmetic functions comprises the steps:
(1) red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder process
According to the composition of raw materials proportioning, the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica selected for use through the quality standard check are soaked in the purifying waste water of 10 times of weight, are heated to 100 ℃ with multi-function extractor, and lixiviate 2h gets leaching liquor one time; The water that adds 8 times of weight in the filter residue again, under same extracting condition lixiviate 2h, the secondary leaching liquor; Twice leaching liquor crossed to merge behind 100 mesh sieves send into vacuum concentration pot and carry out vacuum and concentrate, temperature 60-70 ℃, pressure 0.06-0.08MPa, be concentrated into relative density 1.05, time 3-4h; Through vacuum drying, pressure 0.06-0.08MPa, temperature 65-75 ℃, time 3-4h; The extract of drying was pulverized 80 mesh sieves, and it is standby to make dry powder;
(2) allotment mixing granulation
Press formulation ratio in 100,000 grades of air cleaning workshops, the red sage root of weighing step (1) preparation, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder, put in the CH type trough type mixing machine with the dextrin of formulation ratio and to mix, spray the edible ethanol solution of mass fraction 95%, mixed softwood, with YK-160A type oscillating granulator softwood being crossed 20 mesh sieves granulates, wet granular is in GMP-1 type hot air circulation drying baker drying, temperature 50-60 ℃, 3-4h, be dried to pellet moisture below 5%, dried particle is standby with the whole grain of YK-160A type oscillating granulator 20 mesh sieves;
(3) metering filled capsules, packing
In 100,000 grades of air cleaning workshops, the particulate material of step (3) is adorned capsule with automatic tire bagger, polishing, bottled, seal packing;
(4) product inspection, warehouse-in
Require that according to GMP finished product is carried out every check and measure warehouse-in up to specification.
Remarkable advantage of the present invention is:
(1) raw materials for production of the present invention are made up of the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica.These raw materials are the treasure that motherland's medical science is used for prevent disease, health care.
(2) this reasonable science of filling a prescription is rich in bioactivators such as polysaccharide, flavonoids, tanshinone.General flavone is the significant composition of product of the present invention.
(3) production Technology of the present invention has reached advanced international level.This technology is convenient to operation, can realize that industrialization produces continuously, so production cost is low.
The specific embodiment
Embodiment 1
A kind of composition of raw material of health food of spot-dispelling and cosmetic functions and mass fraction: the red sage root 15%, safflower 16%, Radix Angelicae Sinensis 14%, Radix Codonopsis 21%, the root of Dahurain angelica 17%, dextrin 17%.
The method for preparing the health food of aforesaid spot-dispelling and cosmetic functions comprises the steps:
(1) red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder process
According to the composition of raw materials proportioning, the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica selected for use through the quality standard check are soaked in the purifying waste water of 10 times of weight, are heated to 100 ℃ with multi-function extractor, and lixiviate 2h gets leaching liquor one time; The water that adds 8 times of weight in the filter residue again, under same extracting condition lixiviate 2h, the secondary leaching liquor; Twice leaching liquor crossed to merge behind 100 mesh sieves send into vacuum concentration pot and carry out vacuum and concentrate, 60 ℃ of temperature, are concentrated into relative density 1.05, time 4h at pressure 0.06MPa; Through vacuum drying, pressure 0.06MPa, 65 ℃ of temperature, time 4h; The extract of drying was pulverized 80 mesh sieves, and it is standby to make dry powder;
(2) allotment mixing granulation
Press formulation ratio in 100,000 grades of air cleaning workshops, the red sage root of weighing step (1) preparation, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder, put in the CH type trough type mixing machine with the dextrin of formulation ratio and to mix, spray the edible ethanol solution of mass fraction 95%, mixed softwood, with YK-160A type oscillating granulator softwood being crossed 20 mesh sieves granulates, wet granular is in GMP-1 type hot air circulation drying baker drying, 50 ℃ of temperature, 4h, be dried to pellet moisture below 5%, dried particle is standby with the whole grain of YK-160A type oscillating granulator 20 mesh sieves;
(3) metering filled capsules, packing
In 100,000 grades of air cleaning workshops, the particulate material of step (3) is adorned capsule with automatic tire bagger, polishing, bottled, seal packing;
(4) product inspection, warehouse-in
Require that according to GMP finished product is carried out every check and measure warehouse-in up to specification.
Embodiment 2
A kind of composition of raw material of health food of spot-dispelling and cosmetic functions and mass fraction: the red sage root 17%, safflower 14%, Radix Angelicae Sinensis 16%, Radix Codonopsis 19%, the root of Dahurain angelica 19%, dextrin 15%.
The method for preparing the health food of aforesaid spot-dispelling and cosmetic functions comprises the steps:
(1) red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder process
According to the composition of raw materials proportioning, the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica selected for use through the quality standard check are soaked in the purifying waste water of 10 times of weight, are heated to 100 ℃ with multi-function extractor, and lixiviate 2h gets leaching liquor one time; The water that adds 8 times of weight in the filter residue again, under same extracting condition lixiviate 2h, the secondary leaching liquor; Twice leaching liquor crossed to merge behind 100 mesh sieves send into vacuum concentration pot and carry out vacuum and concentrate, 70 ℃ of temperature, are concentrated into relative density 1.05, time 3h at pressure 0.08MPa; Through vacuum drying, pressure 0.08MPa, 75 ℃ of temperature, time 3h; The extract of drying was pulverized 80 mesh sieves, and it is standby to make dry powder;
(2) allotment mixing granulation
Press formulation ratio in 100,000 grades of air cleaning workshops, the red sage root of weighing step (1) preparation, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder, put in the CH type trough type mixing machine with the dextrin of formulation ratio and to mix, spray the edible ethanol solution of mass fraction 95%, mixed softwood, with YK-160A type oscillating granulator softwood being crossed 20 mesh sieves granulates, wet granular is in GMP-1 type hot air circulation drying baker drying, 60 ℃ of temperature, 3h, be dried to pellet moisture below 5%, dried particle is standby with the whole grain of YK-160A type oscillating granulator 20 mesh sieves;
(3) metering filled capsules, packing
In 100,000 grades of air cleaning workshops, the particulate material of step (3) is adorned capsule with automatic tire bagger, polishing, bottled, seal packing;
(4) product inspection, warehouse-in
Require that according to GMP finished product is carried out every check and measure warehouse-in up to specification.
Embodiment 3
A kind of composition of raw material of health food of spot-dispelling and cosmetic functions and mass fraction: the red sage root 16%, safflower 15%, Radix Angelicae Sinensis 15%, Radix Codonopsis 20%, the root of Dahurain angelica 18%, dextrin 16%.
The method for preparing the health food of aforesaid spot-dispelling and cosmetic functions comprises the steps:
(1) red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder process
According to the composition of raw materials proportioning, the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica selected for use through the quality standard check are soaked in the purifying waste water of 10 times of weight, are heated to 100 ℃ with multi-function extractor, and lixiviate 2h gets leaching liquor one time; The water that adds 8 times of weight in the filter residue again, under same extracting condition lixiviate 2h, the secondary leaching liquor; Twice leaching liquor crossed to merge behind 100 mesh sieves send into vacuum concentration pot and carry out vacuum and concentrate, 65 ℃ of temperature, are concentrated into relative density 1.05, time 3.5h at pressure 0.07MPa; Through vacuum drying, pressure 0.07MPa, 70 ℃ of temperature, time 3.5h; The extract of drying was pulverized 80 mesh sieves, and it is standby to make dry powder;
(2) allotment mixing granulation
Press formulation ratio in 100,000 grades of air cleaning workshops, the red sage root of weighing step (1) preparation, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder, put in the CH type trough type mixing machine with the dextrin of formulation ratio and to mix, spray the edible ethanol solution of mass fraction 95%, mixed softwood, with YK-160A type oscillating granulator softwood being crossed 20 mesh sieves granulates, wet granular is in GMP-1 type hot air circulation drying baker drying, 55 ℃ of temperature, 3.5h, be dried to pellet moisture below 5%, dried particle is standby with the whole grain of YK-160A type oscillating granulator 20 mesh sieves;
(3) metering filled capsules, packing
In 100,000 grades of air cleaning workshops, the particulate material of step (3) is adorned capsule with automatic tire bagger, polishing, bottled, seal packing;
(4) product inspection, warehouse-in
Require that according to GMP finished product is carried out every check and measure warehouse-in up to specification.
Embodiment 4
Show through the human feeding trial result: the experimenter is divided into edible product capsule of the present invention and placebo at random by chloasma color, area situation, and the result shows after 45 days: reaching the control group comparing difference before test-meal group chloasma color integration and self test-meal all has conspicuousness (P<0.05); Reach the control group comparing difference before chloasma area and self test-meal and conspicuousness (P<0.05) is all arranged, test-meal group chloasma area decreased average 13,19%; Test-meal group functions of removing chloasma total effective rate is 65,38%, compares with control group (5,66%), and difference has conspicuousness (P<0.05), and does not have new chloasma generation.Illustrate that product of the present invention has the functions of removing chloasma effect.Before and after the test-meal product of the present invention, every indexs such as routine blood test, blood biochemistry show no obvious abnormalities change, do not observe bad reaction during the test-meal.Illustrate that product of the present invention is very safe.
The above only is preferred embodiment of the present invention, and all equalizations of doing according to the present patent application claim change and modify, and all should belong to covering scope of the present invention.
Claims (3)
1. the health food of a spot-dispelling and cosmetic functions is characterized in that: the composition of raw material and mass fraction: red sage root 15%-17%, safflower 14%-16%, Radix Angelicae Sinensis 14%-16%, Radix Codonopsis 19%-21%, root of Dahurain angelica 17%-19%, dextrin 15%-17%.
2. the health food of spot-dispelling and cosmetic functions according to claim 1 is characterized in that: the composition of raw material and mass fraction: the red sage root 16%, safflower 15%, Radix Angelicae Sinensis 15%, Radix Codonopsis 20%, the root of Dahurain angelica 18%, dextrin 16%.
3. a method for preparing the health food of spot-dispelling and cosmetic functions as claimed in claim 1 is characterized in that: comprise the steps:
(1) red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder process
According to the composition of raw materials proportioning, the red sage root, safflower, Radix Angelicae Sinensis, Radix Codonopsis, the root of Dahurain angelica selected for use through the quality standard check are soaked in the purifying waste water of 10 times of weight, are heated to 100 ℃ with multi-function extractor, and lixiviate 2h gets leaching liquor one time; The water that adds 8 times of weight in the filter residue again, under same extracting condition lixiviate 2h, the secondary leaching liquor; Twice leaching liquor crossed to merge behind 100 mesh sieves send into vacuum concentration pot and carry out vacuum and concentrate, temperature 60-70 ℃, pressure 0.06-0.08MPa, be concentrated into relative density 1.05, time 3-4h; Through vacuum drying, pressure 0.06-0.08MPa, temperature 65-75 ℃, time 3-4h; The extract of drying was pulverized 80 mesh sieves, and it is standby to make dry powder;
(2) allotment mixing granulation
Press formulation ratio in 100,000 grades of air cleaning workshops, the red sage root of weighing step (1) preparation, safflower, Radix Angelicae Sinensis, Radix Codonopsis, root of Dahurain angelica raw material extract powder, put in the CH type trough type mixing machine with the dextrin of formulation ratio and to mix, spray the edible ethanol solution of mass fraction 95%, mixed softwood, with YK-160A type oscillating granulator softwood being crossed 20 mesh sieves granulates, wet granular is in GMP-1 type hot air circulation drying baker drying, temperature 50-60 ℃, 3-4h, be dried to pellet moisture below 5%, dried particle is standby with the whole grain of YK-160A type oscillating granulator 20 mesh sieves;
(3) metering filled capsules, packing
In 100,000 grades of air cleaning workshops, the particulate material of step (3) is adorned capsule with automatic tire bagger, polishing, bottled, seal packing;
(4) product inspection, warehouse-in
Require that according to GMP finished product is carried out every check and measure warehouse-in up to specification.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105455124A (en) * | 2015-11-27 | 2016-04-06 | 黑龙江众生生物工程有限公司 | Wedelia prostrata skin-moistening feature-beautifying granules and preparation method thereof |
CN106138557A (en) * | 2015-04-21 | 2016-11-23 | 李顺达 | A kind of speckle dispelling oil and preparation method thereof |
CN113456732A (en) * | 2021-07-19 | 2021-10-01 | 河北御芝林生物科技有限公司 | Composition for removing chloasma and preparation method thereof |
CN114159493A (en) * | 2020-09-11 | 2022-03-11 | 陕西千芝堂医药保健品有限公司 | Freckle-removing capsule and production process thereof |
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CN1144671A (en) * | 1995-09-07 | 1997-03-12 | 海春旭 | Menstruation-regulating and speckle-removing capsule and preparation thereof |
CN102246962A (en) * | 2011-08-18 | 2011-11-23 | 高益槐 | Health-care food capable of protecting against chemical liver damage and preparation method thereof |
CN102342985A (en) * | 2010-07-28 | 2012-02-08 | 陈登 | Chinese medicinal prescription for treating chloasma |
CN102727404A (en) * | 2011-04-15 | 2012-10-17 | 熊庆超 | Freckle removal liquid |
JP2013001642A (en) * | 2011-06-13 | 2013-01-07 | Ssp Co Ltd | Skin deposited pigment discharge promoting agent |
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2013
- 2013-05-03 CN CN201310159163XA patent/CN103202480A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1144671A (en) * | 1995-09-07 | 1997-03-12 | 海春旭 | Menstruation-regulating and speckle-removing capsule and preparation thereof |
CN102342985A (en) * | 2010-07-28 | 2012-02-08 | 陈登 | Chinese medicinal prescription for treating chloasma |
CN102727404A (en) * | 2011-04-15 | 2012-10-17 | 熊庆超 | Freckle removal liquid |
JP2013001642A (en) * | 2011-06-13 | 2013-01-07 | Ssp Co Ltd | Skin deposited pigment discharge promoting agent |
CN102246962A (en) * | 2011-08-18 | 2011-11-23 | 高益槐 | Health-care food capable of protecting against chemical liver damage and preparation method thereof |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106138557A (en) * | 2015-04-21 | 2016-11-23 | 李顺达 | A kind of speckle dispelling oil and preparation method thereof |
CN105455124A (en) * | 2015-11-27 | 2016-04-06 | 黑龙江众生生物工程有限公司 | Wedelia prostrata skin-moistening feature-beautifying granules and preparation method thereof |
CN114159493A (en) * | 2020-09-11 | 2022-03-11 | 陕西千芝堂医药保健品有限公司 | Freckle-removing capsule and production process thereof |
CN113456732A (en) * | 2021-07-19 | 2021-10-01 | 河北御芝林生物科技有限公司 | Composition for removing chloasma and preparation method thereof |
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Application publication date: 20130717 |