CN103201696B - 化学检测系统的温度控制 - Google Patents
化学检测系统的温度控制 Download PDFInfo
- Publication number
- CN103201696B CN103201696B CN201180050892.0A CN201180050892A CN103201696B CN 103201696 B CN103201696 B CN 103201696B CN 201180050892 A CN201180050892 A CN 201180050892A CN 103201696 B CN103201696 B CN 103201696B
- Authority
- CN
- China
- Prior art keywords
- temperature
- detection device
- chemical detection
- fluid
- sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/20—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using microanalysis, e.g. drop reaction
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
- G05D23/1927—Control of temperature characterised by the use of electric means using a plurality of sensors
- G05D23/193—Control of temperature characterised by the use of electric means using a plurality of sensors sensing the temperaure in different places in thermal relationship with one or more spaces
- G05D23/1931—Control of temperature characterised by the use of electric means using a plurality of sensors sensing the temperaure in different places in thermal relationship with one or more spaces to control the temperature of one space
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/147—Employing temperature sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Automation & Control Theory (AREA)
- Clinical Laboratory Science (AREA)
- Remote Sensing (AREA)
- Hematology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Electrochemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicinal Chemistry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37618510P | 2010-08-23 | 2010-08-23 | |
| US61/376,185 | 2010-08-23 | ||
| PCT/US2011/048840 WO2012027391A1 (en) | 2010-08-23 | 2011-08-23 | Temperature control of chemical detection system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103201696A CN103201696A (zh) | 2013-07-10 |
| CN103201696B true CN103201696B (zh) | 2015-09-23 |
Family
ID=45723776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180050892.0A Expired - Fee Related CN103201696B (zh) | 2010-08-23 | 2011-08-23 | 化学检测系统的温度控制 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9494951B2 (enExample) |
| EP (1) | EP2609476B1 (enExample) |
| JP (1) | JP5889306B2 (enExample) |
| CN (1) | CN103201696B (enExample) |
| WO (1) | WO2012027391A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007334393A1 (en) | 2006-12-14 | 2008-06-26 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US11339430B2 (en) | 2007-07-10 | 2022-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8262900B2 (en) * | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US8776573B2 (en) | 2009-05-29 | 2014-07-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
| TWI580955B (zh) | 2010-06-30 | 2017-05-01 | 生命技術公司 | 離子感測電荷累積電路及方法 |
| US8415177B2 (en) | 2010-06-30 | 2013-04-09 | Life Technologies Corporation | Two-transistor pixel array |
| CN103201696B (zh) | 2010-08-23 | 2015-09-23 | 生命科技股份有限公司 | 化学检测系统的温度控制 |
| US8786331B2 (en) | 2012-05-29 | 2014-07-22 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
| EP2947453B1 (en) * | 2013-01-17 | 2018-09-05 | Hitachi High-Technologies Corporation | Biomolecule measuring device |
| JP2016510895A (ja) | 2013-03-15 | 2016-04-11 | ライフ テクノロジーズ コーポレーション | 一貫性のあるセンサ表面積を有する化学センサ |
| JP6671274B2 (ja) | 2013-03-15 | 2020-03-25 | ライフ テクノロジーズ コーポレーション | 薄伝導性素子を有する化学装置 |
| US20140336063A1 (en) | 2013-05-09 | 2014-11-13 | Life Technologies Corporation | Windowed Sequencing |
| US11135592B2 (en) * | 2013-06-27 | 2021-10-05 | Quark Biosciences Taiwan, Inc. | Multiplex slide plate device having storage tank |
| CN103752360B (zh) * | 2013-12-30 | 2015-08-19 | 西安天隆科技有限公司 | 一种用于生物化学反应的热学模块 |
| TWI515041B (zh) * | 2014-01-29 | 2016-01-01 | 國立屏東科技大學 | 微流體混合裝置 |
| TWI794007B (zh) | 2014-12-18 | 2023-02-21 | 美商生命技術公司 | 積體電路裝置、感測器裝置及積體電路 |
| US10077472B2 (en) | 2014-12-18 | 2018-09-18 | Life Technologies Corporation | High data rate integrated circuit with power management |
| TWI697668B (zh) * | 2014-12-18 | 2020-07-01 | 美商生命技術公司 | 感測器裝置及用於操作包含一核酸定序系統的方法 |
| CN105626226B (zh) * | 2015-12-25 | 2018-06-08 | 潍柴动力股份有限公司 | 一种发动机散热控制系统及其控制方法 |
| DE102017108120A1 (de) * | 2017-04-13 | 2018-10-18 | Laser-Laboratorium Göttingen e.V. | Analysevorrichtung |
| CN107941380A (zh) * | 2017-12-18 | 2018-04-20 | 天津市计量监督检测科学研究院 | 一种聚合酶链式反应分析仪多通道温度校准装置 |
| CN112714872B (zh) * | 2018-09-25 | 2024-04-30 | 京瓷株式会社 | 向检体处理设备的检体导入方法 |
| CN109405906B (zh) * | 2018-11-23 | 2024-08-06 | 宁波水表(集团)股份有限公司 | 一种流量计量装置以及流量计量方法 |
| EP3899032A2 (en) | 2018-12-20 | 2021-10-27 | Omniome, Inc. | Temperature control for analysis of nucleic acids and other analytes |
| CN112175816B (zh) * | 2019-07-05 | 2025-10-10 | 赛纳生物科技(北京)有限公司 | 一种试剂控温的核酸测序系统 |
| CN110763641B (zh) * | 2019-11-29 | 2024-04-09 | 京东方科技集团股份有限公司 | 检测装置和检测方法 |
| WO2021138106A1 (en) * | 2019-12-30 | 2021-07-08 | Illumina, Inc. | Flow cell assemblies and related reagent selector valves |
| CN114452913A (zh) * | 2022-02-23 | 2022-05-10 | 厦门芯曙光科技有限公司 | 一种流动化学反应模块及其自动化实验装置 |
| US20230296489A1 (en) * | 2022-03-18 | 2023-09-21 | Elephas Biosciences Corporation | Flow cell and sample sorting system |
| CN117126726B (zh) * | 2023-08-29 | 2024-11-12 | 杭州智灵龙生物科技有限公司 | 检测装置及其电化学发光检测方法 |
| WO2025080502A1 (en) * | 2023-10-13 | 2025-04-17 | Regents Of The University Of Minnesota | Ion sensitive field effect transistors with europium ion probes |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07121248A (ja) * | 1993-10-27 | 1995-05-12 | Smc Corp | 流体の恒温方法及びその装置 |
| US5641400A (en) * | 1994-10-19 | 1997-06-24 | Hewlett-Packard Company | Use of temperature control devices in miniaturized planar column devices and miniaturized total analysis systems |
| US7015030B1 (en) * | 1999-07-28 | 2006-03-21 | Genset S.A. | Microfluidic devices and uses thereof in biochemical processes |
| US7118917B2 (en) * | 2001-03-07 | 2006-10-10 | Symyx Technologies, Inc. | Parallel flow reactor having improved thermal control |
| CN101196750A (zh) * | 2006-12-07 | 2008-06-11 | 北京北方微电子基地设备工艺研究中心有限责任公司 | 反应腔室 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318885A (en) | 1979-09-10 | 1982-03-09 | Olympus Optical Co., Ltd. | Liquid treating device for chemical analysis apparatus |
| JPS5639455A (en) * | 1979-09-10 | 1981-04-15 | Olympus Optical Co Ltd | Method and device for measuring ion concentration |
| US4897169A (en) * | 1986-08-18 | 1990-01-30 | Milan Bier | Process and apparatus for recycling isoelectric focusing and isotachophoresis |
| US5221448A (en) * | 1990-01-25 | 1993-06-22 | Spectra-Physics Analytical, Inc. | Buffer gradient and temperature gradient capillary electrophoresis |
| ATE208658T1 (de) * | 1993-07-28 | 2001-11-15 | Pe Corp Ny | Vorrichtung und verfahren zur nukleinsäurevervielfältigung |
| US5885470A (en) | 1997-04-14 | 1999-03-23 | Caliper Technologies Corporation | Controlled fluid transport in microfabricated polymeric substrates |
| JP3664888B2 (ja) | 1998-08-28 | 2005-06-29 | 富士電機ホールディングス株式会社 | Bodバイオセンサ測定装置 |
| US6939451B2 (en) * | 2000-09-19 | 2005-09-06 | Aclara Biosciences, Inc. | Microfluidic chip having integrated electrodes |
| US6942018B2 (en) * | 2001-09-28 | 2005-09-13 | The Board Of Trustees Of The Leland Stanford Junior University | Electroosmotic microchannel cooling system |
| US6601438B2 (en) * | 2001-09-28 | 2003-08-05 | Systec, Inc. | Apparatus for conducting high-temperature liquid chromotography analysis |
| AU2002351187A1 (en) * | 2001-11-30 | 2003-06-17 | Fluidigm Corporation | Microfluidic device and methods of using same |
| US7223371B2 (en) * | 2002-03-14 | 2007-05-29 | Micronics, Inc. | Microfluidic channel network device |
| US6986382B2 (en) | 2002-11-01 | 2006-01-17 | Cooligy Inc. | Interwoven manifolds for pressure drop reduction in microchannel heat exchangers |
| US7517498B2 (en) * | 2003-08-19 | 2009-04-14 | Agilent Technologies, Inc. | Apparatus for substrate handling |
| JP3903183B2 (ja) * | 2004-02-03 | 2007-04-11 | 独立行政法人物質・材料研究機構 | 遺伝子検出電界効果デバイスおよびこれを用いた遺伝子多型解析方法 |
| US20080152543A1 (en) * | 2006-11-22 | 2008-06-26 | Hideyuki Karaki | Temperature regulation method of microfluidic chip, sample analysis system and microfluidic chip |
| AU2007334393A1 (en) * | 2006-12-14 | 2008-06-26 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8262900B2 (en) * | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| JP2012506557A (ja) * | 2008-10-22 | 2012-03-15 | ライフ テクノロジーズ コーポレーション | 生物学的および化学的分析のための集積センサアレイ |
| CN103201696B (zh) | 2010-08-23 | 2015-09-23 | 生命科技股份有限公司 | 化学检测系统的温度控制 |
-
2011
- 2011-08-23 CN CN201180050892.0A patent/CN103201696B/zh not_active Expired - Fee Related
- 2011-08-23 US US13/216,008 patent/US9494951B2/en active Active
- 2011-08-23 JP JP2013526102A patent/JP5889306B2/ja not_active Expired - Fee Related
- 2011-08-23 WO PCT/US2011/048840 patent/WO2012027391A1/en not_active Ceased
- 2011-08-23 EP EP11820540.0A patent/EP2609476B1/en not_active Not-in-force
-
2016
- 2016-11-14 US US15/351,253 patent/US10578578B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07121248A (ja) * | 1993-10-27 | 1995-05-12 | Smc Corp | 流体の恒温方法及びその装置 |
| US5641400A (en) * | 1994-10-19 | 1997-06-24 | Hewlett-Packard Company | Use of temperature control devices in miniaturized planar column devices and miniaturized total analysis systems |
| US7015030B1 (en) * | 1999-07-28 | 2006-03-21 | Genset S.A. | Microfluidic devices and uses thereof in biochemical processes |
| US7118917B2 (en) * | 2001-03-07 | 2006-10-10 | Symyx Technologies, Inc. | Parallel flow reactor having improved thermal control |
| CN101196750A (zh) * | 2006-12-07 | 2008-06-11 | 北京北方微电子基地设备工艺研究中心有限责任公司 | 反应腔室 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2609476B1 (en) | 2022-04-20 |
| US10578578B2 (en) | 2020-03-03 |
| US20120067723A1 (en) | 2012-03-22 |
| EP2609476A4 (en) | 2017-08-16 |
| WO2012027391A1 (en) | 2012-03-01 |
| JP2013536441A (ja) | 2013-09-19 |
| US9494951B2 (en) | 2016-11-15 |
| US20170059516A1 (en) | 2017-03-02 |
| CN103201696A (zh) | 2013-07-10 |
| EP2609476A1 (en) | 2013-07-03 |
| JP5889306B2 (ja) | 2016-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150923 |