Summary of the invention
The invention provides a kind of beverage wine with the effect of kidney-nourishing pillow (or cap) for hair-care and health, its Raw is selected from the integration of drinking and medicinal herbs material of " being food and medicine " that meet Ministry of Health's regulation.Eat and show through long-term human body, the present invention has clear and definite effect, and security is good, and its cost of manufacture is low, wide application, and applicable broad masses of the people drink.
The invention discloses for achieving the above object following technology contents:
There is a beverage wine for kidney-nourishing pillow (or cap) for hair-care and health effect, it is characterized in that it is made up of white wine and the compound Chinese medicine material of following portions by weight: white wine: compound Chinese medicine material is 1000: 7.5~100; Wherein said compound Chinese medicine material is:
1~20 part of raspberry, 1~20 part of RHIZOMA POLYGONATI PREPARATA, 1~20 part of mulberries, 1~20 part, date,
1~20 part of Semen Sesami Nigrum, 1~20 part of matrimony vine, 0.5~5 part, Radix Glycyrrhizae, 1~10 part of honey.
The preferred beverage wine of the present invention, wherein white wine: the parts by weight of compound Chinese medicine material are 1000: 15~80; Described compound Chinese medicine material is:
1~15 part of raspberry, 1~15 part of RHIZOMA POLYGONATI PREPARATA, 1~15 part of mulberries, 1~18 part, date,
1~15 part of Semen Sesami Nigrum, 1~18 part of matrimony vine, 1~5 part, Radix Glycyrrhizae, 3~10 parts of honey.
The present invention further discloses the preparation method with kidney-nourishing pillow (or cap) for hair-care and health effect beverage wine, it is characterized in that being undertaken by following step:
(1) described traditional Chinese medicinal material raw materials is selected to section, clean up, dry;
(2) described Chinese medicinal materials is placed in to container, adds the white wine of described weight fraction, stir, sealing, soak at room temperature 30-40 days;
(3) soak solution of step (2) gained is filtered, obtain filtrate;
(4) to the honey that adds described weight ratio in the filtrate of step (3) gained, the dissolving that stirs, obtains finished product;
Beneficial kidney and blackening hair beverage wine of the present invention, final finished is shallow palm fibre to brown clear liquid, without the visible tramp material of naked eyes, delicate fragrance is pure, has compound fragrance elegant, harmony, mouthfeel alcohol and, micro-hardship.Selected base wine meets standard GB/T 2757 and specifies, selected Chinese medicinal materials all meets Pharmacopoeia of the People's Republic of China regulation, wherein matrimony vine also meets standard GB/T/T 18672 and specifies, honey meets standard GB/T 14963 and specifies, date meets standard GB/T/T 5835 and specifies, Radix Glycyrrhizae meets standard GB/T/T 19618 and specifies, sesame meets standard GB/T/T 11761 and specifies, is meticulously to select and have better nutritivity to be worth and pharmaceutical use Chinese medicinal materials.
The side of Chinese medicinal materials that the present invention uses separates as follows:
Raspberry: taste is sweet, sour, warm in nature, returns liver, kidney, urinary bladder channel, has supplementing the kidney to control the nocturnal contracting urine, the effect nourishing the liver to improve visual acuity, and for emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, the dark dim-sighted disease of waiting of order.
RHIZOMA POLYGONATI PREPARATA: taste is sweet, property is flat, returns spleen, lung, kidney channel, has boosting qi and nourishing yin, invigorating the spleen, moistening lung, effect of kidney-nourishing, for deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, dry food is few, deficiency syndrome of the lung cough caused by dryness, the hemoptysis of coughing of chattering, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior heat disappears and exhausts.
Mulberries: taste is sweet, sour, cold in nature, the thoughts of returning home, liver, kidney channel, the effect that there is nourishing YIN and supplementing blood, promotes the production of body fluid and moisturize, for the hepatic and renal YIN deficiency, dizzy dizzy, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty; Interior heat is quenched one's thirst, the dry constipation of intestines.
Date: taste is sweet, warm in nature, return spleen, stomach, the heart channel of Hang-Shaoyin, there is invigorating the spleen and replenishing QI, effect of nourishing blood to tranquillize the mind, few for insufficiency of the spleen food, weak loose stool, woman hysteria.
Semen Sesami Nigrum: taste is sweet, property is flat, returns liver, kidney, large intestine channel, has invigorating the liver and kidney, benefiting essence-blood, ease constipation is dry, for blood and essence asthenia, dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, the dry constipation of intestines.
Matrimony vine: taste is sweet, property is flat, returns liver, kidney channel, has nourishing liver and kidneyly, and effect of replenishing vital essence to improve eyesight, loses for consumptive disease essence, soreness of waist and knee joint, and impotence and seminal emission, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear.Rich vitamin A, B, C and trace elements calcium, phosphorus, iron etc. in matrimony vine, long-term edible to being deficient in vitamin and trace element and the Huang that causes is sent out, white hair, lusterless complexion, xerosis cutis etc. all have significant curative effect.
Radix Glycyrrhizae: taste is sweet, property is flat, and the thoughts of returning home, spleen, stomach, lung channel, have invigoration spleen qi, clearing heat and detoxicating, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription, for weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, gastral cavity abdomen, the anxious pain of four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Honey: taste is sweet, property is flat, returns spleen, lung, large intestine channel, has bowl spares, moisturize, pain relieving, effect of removing toxic substances, for the empty pain of gastral cavity abdomen, dryness of the lung dry cough, the dry constipation of intestines, separates Aconitum medicine poison.
Physics and chemistry, the health detection index of beneficial kidney and blackening hair beverage wine prepared by the present invention are as follows:
Healht-care wine of the present invention can prevent and alleviate deficiency of spleen and stomach, has the effect of beneficial kidney and blackening hair.Concrete pharmacological evaluation is as follows:
One, anti-aging test
Use Rotary Evaporators to be concentrated into thick paste shape the present invention (embodiment 1-5), add the base wine containing 15% alcohol concn warm, be finally mixed be respectively equivalent to 20mL/mL of the present invention to sample solution, gavage is to sample.
Test is divided into 6 groups, and 10 every group Wistar kind rats, are divided into embodiment 1-5 group and control group, is 0.2mL to sample volume, and control group is given and equal-volume physiological saline.All groups are given sample 30d continuously, record the situations such as tested rat behavior, activity, death and toxic reaction, after nursing 30d, adopt eye socket hematometry, and conventional method obtains determination of serum related index.Experimental result is in table 1:
The variation of table 1 pharmaceutical composition of the present invention to SOD, MDA content and GSH-Px activity in rat blood serum
Group order |
n |
MDA(nmol/ml) |
SOD(U/ml) |
GSH-Px(U/ml) |
Control group |
10 |
11.78±1.57 |
88.53±8.54 |
126.57±21.36 |
Embodiment 1 |
10 |
7.59±1.81
a |
113.73±7.78
a |
205.47±22.87
a |
Embodiment 2 |
10 |
8.21±1.53
a |
110.32±8.21 |
199.24±26.58
a |
Embodiment 3 |
10 |
8.01±1.21
a |
110.21±7.36
a |
198.20±23.32
a |
Embodiment 4 |
10 |
8.11±1.32
a |
109.52±6.35
a |
200.31±25.32
a |
Embodiment 5 |
10 |
8.50±1.01
a |
110.36±7.52
a |
197.32±25.12
a |
A: with relatively p < 0.05 of control group
Result: rat blood serum mda (MDA) content of embodiment 1-5 group has reduction (P<0.05) significantly compared with control group, show that embodiment of the present invention 1-5 group has the effect that reduces rat blood serum mda (MDA) content in use, can lower to a certain extent the liver injury that body is caused by peroxidation, thereby alleviate the aging of body.Rat blood serum superoxide-dismutase (SOD) activity of embodiment of the present invention 1-5 group has raise significantly (P<0.05) compared with control group, embodiment 1-5 group all has remarkable rising to the activity of rat blood serum Selenoperoxidase (GSH-Px), relatively has significant significant difference (P<0.05) with control group.
Conclusion: the present composition can obviously improve blood free radicals metabolism and aging-resistant effect.
Two, kidney-nourishing test
Use Rotary Evaporators to be concentrated into thick paste shape the present invention (embodiment 1-5), add the base wine containing 15% alcohol concn warm, be finally mixed with respectively concentration and be equivalent to 20mL/mL of the present invention to sample solution, gavage is to sample.
Test is divided into 7 groups, and 10 every group Wistar kind rats (180 ± 10g), are divided into embodiment 1-5 group and contrast (sham-operation) group, model group.Embodiment 1-5 group and model group are carried out 5/6 kidney surgery; Control group is only opened abdominal cavity, does not nephrectomize.Kidney surgery was carried out after one week, carried out gavage to sample, and embodiment 1-5 group is respectively 0.2mL to sample dosage, and control group and model group are given and equal-volume physiological saline.All groups are given sample 30d continuously, record the situations such as tested rat behavior, activity, death and toxic reaction.Feed after 30d, collect each group of 24h urine, detect urinary protein excretion;
The variation of 5 groups of test rat body weights of table 2 and 24h quantity of proteinuria
A: with relatively p < 0.05 of control group; B: with relatively p < 0.05 of model group
Result: before modeling, respectively organize body weight there was no significant difference, give embodiment 1-5 group and all obviously increases of control group body weight after sample, and relatively have significant difference before modeling; Embodiment 1-5 group body weight all obviously increases compared with modeling group, relatively has significant difference with modeling group.Show that the present invention has certain kidney-nourishing effect, can improve the immunizing power of body.Embodiment 1-5 group can significantly reduce 24h quantity of proteinuria, has significant difference compared with modeling group.
Conclusion: the present invention has the ability of certain anti-renal lesions, has the effect that improves immunity of organisms.
Three, pharmacological testing conclusion
Above-mentioned pharmacology result shows that the present invention has the effect that reduces rat blood serum mda (MDA) content in use, the liver injury that can improve to a certain extent blood free radicals metabolism and be caused by peroxidation, thereby alleviate the aging of body, also there is the ability of certain anti-renal lesions, can improve immunity of organisms.
The positively effect that beneficial kidney and blackening hair beverage wine prepared by the present invention compared with prior art had is:
(1) experience that this formula is controlled by using for reference the dialectical opinion of distinguished veteran doctors of TCM, taking " strengthening vital QI to eliminate pathogenic factors " as main principle, focuses on the theory of conditioning and health, concentrates the function balance of organs such as regulating spleen, kidney; Raw material is selected from the material of " being food and medicine " that conform with the regulations, edible and medicinal through long term human, has effect really bright, the feature that security is good.
(2) this its cost of manufacture of filling a prescription is low, wide application, and applicable broad masses of the people drink.Full side is major-minor clearly demarcated, is kidney spleen for the key of aging, tool tonifying kidney and benefiting sperm, and the merit of invigorating the spleen and benefiting QI, has good efficacy to prevention deficiency of spleen and stomach and blood and essence asthenia.Using method: take the present invention's benefit kidney and blackening hair beverage wine, every day each 1 time sooner or later, each 30-50 milliliter.
(3) Chinese medicinal materials kind involved in the present invention is few, and preparation is convenient, and product safety is effectively stable, has and tonifies the liver and kidney, and the good efficacy of invigorating the spleen and benefiting QI, is suitable for crowd wide.
Embodiment
Below in conjunction with embodiment, the present invention is further described, and following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.Various traditional Chinese medicinal material raw materials of the present invention all has commercially available." part " in following examples refers to kg.
Embodiment 1
Get 1 part of raspberry, 1 part of RHIZOMA POLYGONATI PREPARATA, 1 part of mulberries, 1 part, date, 1 part of Semen Sesami Nigrum, 1 part of matrimony vine, 0.1 part of clean, oven dry of Radix Glycyrrhizae, is added in terrine, adds 1000 parts of white wine, and brewed 30 days of normal temperature lower seal, filters, and adds 1 part of honey allotment to obtain product.
Embodiment 2
Get 5 parts of raspberries, 5 parts of RHIZOMA POLYGONATI PREPARATAs, 5 parts of mulberries, 5 parts, date, 5 parts of Semen Sesami Nigrums, 5 parts of matrimony vines, 0.2 part of clean, oven dry of Radix Glycyrrhizae, is added in terrine, adds 1000 parts of white wine, and brewed 30 days of normal temperature lower seal, filters, and adds 10 parts of honey allotments to obtain product.
Embodiment 3
Get 10 parts of raspberries, 10 parts of RHIZOMA POLYGONATI PREPARATAs, 10 parts of mulberries, 10 parts, date, 10 parts of Semen Sesami Nigrums, 10 parts of matrimony vines, 0.5 part of clean, oven dry of Radix Glycyrrhizae, is added in terrine, add 1000 parts of white wine, brewed 30 days of normal temperature lower seal, filters, and adds 10 parts of honey allotments to obtain product.
Embodiment 4
Get 5 parts of raspberries, 1 part of RHIZOMA POLYGONATI PREPARATA, 8 parts of mulberries, 10 parts, date, 8 parts of Semen Sesami Nigrums, 3 parts of matrimony vines, 1 part of clean, oven dry of Radix Glycyrrhizae, is added in terrine, adds 1000 parts of white wine, and brewed 30 days of normal temperature lower seal, filters, and adds 8 parts of honey allotments to obtain product.
Embodiment 5
Get 10 parts of raspberries, 5 parts of RHIZOMA POLYGONATI PREPARATAs, 5 parts of mulberries, 10 parts, date, 10 parts of Semen Sesami Nigrums, 5 parts of matrimony vines, 1 part of clean, oven dry of Radix Glycyrrhizae, is added in terrine, adds 1000 parts of white wine, and brewed 30 days of normal temperature lower seal, filters, and adds 8 parts of honey allotments to obtain product.
The actual effect of drinking of the present invention:
The present invention is adjusting the rear use of prescription 1 year, shows certain curative effect to preventing and alleviating deficiency of spleen and stomach symptom.Be that deficiency of spleen and stomach amounts to 39 30-55 year middle-aged male volunteer and forms in the edible test of test group a control group being formed by 16 healthy 30-55 year middle-aged male volunteer and 23 through tcm diagnosis, sooner or later respectively take the present invention 1 time everyone every day, each 50 milliliters, take continuously 3 months, all volunteers all do not accept to have with the present invention medicine or the treatment of similar action during this time.In test group, 19 people's sleep states improve, and the deficiency of spleen and stomach symptoms such as 14 people's soreness of the waist and knees, spiritlessness and weakness are alleviated to some extent; In control group, 11 people's sleeps improve, and 5 people stool are more smooth and easy.All volunteers are showed no the ill symptomses such as dizziness, headache, heartburn, stomachache, gasteremphraxis, appetite is poor during taking the present invention, and all private prosecution health muscle power, immunizing power are strengthened to some extent.Test group volunteer was continued to take the present invention after 3 months, carry out 24 h quantity of proteinurias and detect, find that detected result, with respect to taking the front 0.2g/24h that on average decreases by, shows that the present invention has the ability of certain alleviation renal lesions, can improve immunity of organisms.