CN103185637A - Optical system for spectrophotometer of biochemical analyzer - Google Patents

Optical system for spectrophotometer of biochemical analyzer Download PDF

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Publication number
CN103185637A
CN103185637A CN201110451089XA CN201110451089A CN103185637A CN 103185637 A CN103185637 A CN 103185637A CN 201110451089X A CN201110451089X A CN 201110451089XA CN 201110451089 A CN201110451089 A CN 201110451089A CN 103185637 A CN103185637 A CN 103185637A
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China
Prior art keywords
cuvette
lens
optical
light
beam splitting
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CN201110451089XA
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Chinese (zh)
Inventor
李如忠
郑东
卫君超
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SHANGHAI FENGHUI MEDICAL TECHNOLOGY CO LTD
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SHANGHAI FENGHUI MEDICAL TECHNOLOGY CO LTD
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Priority to CN201110451089XA priority Critical patent/CN103185637A/en
Publication of CN103185637A publication Critical patent/CN103185637A/en
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Abstract

The invention discloses an optical system for a spectrophotometer of a biochemical analyzer. The optical system for the spectrophotometer of the biochemical analyzer comprises an illuminating system, a beam splitting system and a signal processing system, wherein the illuminating system comprises a light source, a lens, a cuvette and a focusing lens, and the beam splitting system comprises half lenses, optical filters and a receiving photodiode. The light source, the lens, the cuvette and the focusing lens are arranged in sequence. The light source transmits rays, and the rays are collimated through the lens and are radiated into the cuvette in parallel. The rays are radiated into the focusing lens in parallel after penetrating through a sample arranged in the cuvette. Parallel light beams are used as an optical signal and transmitted to the beam splitting system after being focused to be a point light source. The optical signal passes through sixteen half lenses in sequence, and when the optical signal passes through each half lens, a light beam with a designated wavelength is reflected to the corresponding optical filter. The optical signal is converted into a digital signal through the photodiode and transmitted to the signal processing system to be processed in a comparison mode. The optical system for the spectrophotometer of the biochemical analyzer improves the detecting efficiency and the detecting precision.

Description

Be used for the spectrophotometric optical system on the Biochemical Analyzer
Technical field
The present invention relates to biomedical measurement and technical field of medical instruments, particularly a kind of for the spectrophotometric optical system on the Biochemical Analyzer.
Background technology
Automatic clinical chemistry analyzer is mainly used in clinical blood, and the biochemistry in the humoral sample and the fast quantitative analysis of chemical constitution, automatic clinical chemistry analyzer are the conventional sense instruments of modern hospital.
As the critical component of automatic clinical chemistry analyzer, spectrophotometric performance becomes the principal element that determines the automatic clinical chemistry analyzer precision index.In numerous spectrophotometric beam splitting systems, according to light splitting sequencing difference, preceding light splitting and back beam splitting system can be arranged; According to the difference of the chromatic dispersion device of practicality, the beam splitting system of prism, grating and optical filtering chip can be arranged; And optical filtering chip beam splitting system, because a kind of optical filter can only have filter effect to certain certain wavelengths, be difficult to accomplish that the spectrum of properties of multi-wavelength detects, so the common general form of rotating filtering sheet that comprises of optical filtering chip beam splitting system is selected wavelength more on the market.The beam splitting system of this form needs to consume the regular hour when selecting wavelength; And because the characteristic of its rotation has been brought certain instability and failure rate.And the light path system of the discrete fully-automatic analyzer in the market eight road beam splitting systems that adopt once can only be done the detection of eight biochemical indicators to sample more, have retrained the efficient of analytical work greatly, simultaneously also because repeatedly comparison has influenced the detection comparison accuracy.
Summary of the invention
Technical matters to be solved by this invention provides a kind of for the spectrophotometric optical system on the Biochemical Analyzer, its improved detect efficient, also improved simultaneously the precision that detects.
For solveing the technical problem, the invention provides a kind of for the spectrophotometric optical system on the Biochemical Analyzer, it is characterized in that it comprises illuminator, beam splitting system and signal processing system, wherein illuminator comprises light source, lens, cuvette, condenser lens; Beam splitting system comprises semi-permeable mirror, optical filter, reception photodiode, light source, lens, cuvette, condenser lens are arranged in order, the source emissioning light line is through parallel injecting in the cuvette after the collimated, after light sees through sample in the cuvette, the parallel condenser lens of injecting again, after parallel beam is focused into pointolite, be transferred in the beam splitting system as light signal, light signal is successively by 16 semi-permeable mirrors, every through a slice semi-permeable mirror, can be with the beam reflection of specified wavelength to its corresponding optical filter; Light signal is converted to digital signal by photodiode by light signal again, and transfers to signal processing system and compare processing.
Positive progressive effect of the present invention is: the invention solves optical filtering chip beam splitting system and select wavelength long defective consuming time; The present invention once can do the detection of 16 biochemical indicators to sample, improved greatly detect efficient, also improved simultaneously the precision that detects; Owing to used a light source, improved the degree of accuracy of colorimetric and detection.The present invention is simple in structure, stable performance, resolution height, and good reproducibility.
Description of drawings
Fig. 1 is the structured flowchart of one embodiment of the invention.
Embodiment
Lift a preferred embodiment below, and come the clearer the present invention that intactly illustrates by reference to the accompanying drawings.
As shown in Figure 1, the spectrophotometric optical system that the present invention is used on the Biochemical Analyzer comprises illuminator 1, beam splitting system 2 and signal processing system 3, wherein illuminator 1 comprises light source 4, lens 5, cuvette 6, condenser lens 7, and light source 4, lens 5, cuvette 6, condenser lens 7 are arranged in order; Beam splitting system 2 comprises semi-permeable mirror 8, optical filter 9, receives with photodiode 10.The spectrophotometric optical system integral body that the present invention is used on the Biochemical Analyzer is back light splitting optical filtering chip beam splitting system, and uses a light source, has improved the degree of accuracy of colorimetric and detection.Before optical filter 9, add semi-permeable mirror 8, make optical filter 9 be in stationary state, need not to rotatablely move.The quantity of semi-permeable mirror 8 is 16, and the quantity of optical filter is 16.
In illuminator 1, light source 4 emission light are through parallel the injecting in the cuvette 6 in lens 5 collimation backs, after light sees through sample in the cuvette 6, and the parallel condenser lens 7 of injecting again, after parallel beam is focused into pointolite, be transferred in the beam splitting system 2 as light signal.In beam splitting system 2, light signal is successively by 16 semi-permeable mirrors 8, and is every through a slice semi-permeable mirror 8, can be with the beam reflection of specified wavelength to its corresponding optical filter 9, other wavelength light signals are not subjected to the influence of this sheet semi-permeable mirror 8, continue to transfer to down on a slice semi-permeable mirror 8; Can obtain ten six tunnel wavelength light signals by that analogy; Light signal is converted to digital signal by photodiode 10 by light signal again, and transfers to signal processing system 3 and compare processing, thereby finishes the optical detection task of biochemical instruments.The invention solves optical filtering chip beam splitting system and select wavelength long defective consuming time; The present invention once can do the detection of 16 biochemical indicators to sample, improved greatly detect efficient, also improved simultaneously the precision that detects; Owing to used a light source, improved the degree of accuracy of colorimetric and detection.
Though more than described the specific embodiment of the present invention, it will be understood by those of skill in the art that these only illustrate, under the prerequisite that does not deviate from principle of the present invention and essence, can make numerous variations or modification to these embodiments.Therefore, protection scope of the present invention is limited by appended claims.

Claims (1)

1. a spectrophotometric optical system that is used on the Biochemical Analyzer is characterized in that it comprises illuminator, beam splitting system and signal processing system, and wherein illuminator comprises light source, lens, cuvette, condenser lens; Beam splitting system comprises semi-permeable mirror, optical filter, reception photodiode, light source, lens, cuvette, condenser lens are arranged in order, the source emissioning light line is through parallel injecting in the cuvette after the collimated, after light sees through sample in the cuvette, the parallel condenser lens of injecting again, after parallel beam is focused into pointolite, be transferred in the beam splitting system as light signal, light signal is successively by 16 semi-permeable mirrors, every through a slice semi-permeable mirror, can be with the beam reflection of specified wavelength to its corresponding optical filter; Light signal is converted to digital signal by photodiode by light signal again, and transfers to signal processing system and compare processing.
CN201110451089XA 2011-12-28 2011-12-28 Optical system for spectrophotometer of biochemical analyzer Pending CN103185637A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201110451089XA CN103185637A (en) 2011-12-28 2011-12-28 Optical system for spectrophotometer of biochemical analyzer

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Application Number Priority Date Filing Date Title
CN201110451089XA CN103185637A (en) 2011-12-28 2011-12-28 Optical system for spectrophotometer of biochemical analyzer

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CN103185637A true CN103185637A (en) 2013-07-03

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104862220A (en) * 2014-02-20 2015-08-26 精工爱普生株式会社 Nucleic Acid Amplification Reaction Apparatus
CN106441564A (en) * 2015-08-05 2017-02-22 唯亚威通讯技术有限公司 Optical filter and spectrometer
CN108535468A (en) * 2018-04-18 2018-09-14 苗艳君 A kind of reproductive medicine biochemical immunity testing equipment
CN109060672A (en) * 2018-08-22 2018-12-21 广州万孚生物技术股份有限公司 Systems for optical inspection
US10190910B2 (en) 2014-01-31 2019-01-29 Viavi Solutions Inc. Optical filter and spectrometer
CN110426360A (en) * 2019-08-27 2019-11-08 深圳市国赛生物技术有限公司 Spectrophotometer
CN113820277A (en) * 2021-09-14 2021-12-21 四川沃文特生物技术有限公司 Data acquisition system and optical detection system for sample analyzer

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CN2738220Y (en) * 2004-10-09 2005-11-02 上海合意检验设备有限公司 Lens expanding beam splitting multiwavelength photometer
CN1720335A (en) * 2002-12-06 2006-01-11 霍夫曼-拉罗奇有限公司 Multiplex assay detection of pathogenic organisms
CN1746659A (en) * 2004-09-07 2006-03-15 三星电子株式会社 Optical detection apparatus and the multi-channel sample analyzer that uses this device
CN101075017A (en) * 2006-05-19 2007-11-21 Jds尤尼弗思公司 Gain normalized for mems control system
CN101504371A (en) * 2009-03-05 2009-08-12 中国检验检疫科学研究院 Quantitative determination instrument for melamine content in liquid milk
CN202404012U (en) * 2011-12-28 2012-08-29 上海丰汇医学科技有限公司 Optical system of spectrophotometer for biochemical analyzer

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Publication number Priority date Publication date Assignee Title
CN1720335A (en) * 2002-12-06 2006-01-11 霍夫曼-拉罗奇有限公司 Multiplex assay detection of pathogenic organisms
CN1746659A (en) * 2004-09-07 2006-03-15 三星电子株式会社 Optical detection apparatus and the multi-channel sample analyzer that uses this device
CN2738220Y (en) * 2004-10-09 2005-11-02 上海合意检验设备有限公司 Lens expanding beam splitting multiwavelength photometer
CN101075017A (en) * 2006-05-19 2007-11-21 Jds尤尼弗思公司 Gain normalized for mems control system
CN101504371A (en) * 2009-03-05 2009-08-12 中国检验检疫科学研究院 Quantitative determination instrument for melamine content in liquid milk
CN202404012U (en) * 2011-12-28 2012-08-29 上海丰汇医学科技有限公司 Optical system of spectrophotometer for biochemical analyzer

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10190910B2 (en) 2014-01-31 2019-01-29 Viavi Solutions Inc. Optical filter and spectrometer
CN104862220A (en) * 2014-02-20 2015-08-26 精工爱普生株式会社 Nucleic Acid Amplification Reaction Apparatus
CN106441564A (en) * 2015-08-05 2017-02-22 唯亚威通讯技术有限公司 Optical filter and spectrometer
US10048127B2 (en) 2015-08-05 2018-08-14 Viavi Solutions Inc. Optical filter and spectrometer
CN106441564B (en) * 2015-08-05 2019-01-11 唯亚威通讯技术有限公司 Optical filter and spectroscope
CN109579990A (en) * 2015-08-05 2019-04-05 唯亚威通讯技术有限公司 Optical filter and spectroscope
US10753793B2 (en) 2015-08-05 2020-08-25 Viavi Solutions Inc. Optical filter and spectrometer
US11237049B2 (en) 2015-08-05 2022-02-01 Viavi Solutions Inc. Optical filter and spectrometer
CN108535468A (en) * 2018-04-18 2018-09-14 苗艳君 A kind of reproductive medicine biochemical immunity testing equipment
CN109060672A (en) * 2018-08-22 2018-12-21 广州万孚生物技术股份有限公司 Systems for optical inspection
CN110426360A (en) * 2019-08-27 2019-11-08 深圳市国赛生物技术有限公司 Spectrophotometer
CN113820277A (en) * 2021-09-14 2021-12-21 四川沃文特生物技术有限公司 Data acquisition system and optical detection system for sample analyzer

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Application publication date: 20130703