CN102539346A - Optical system of full-automatic biochemical analyzer - Google Patents

Optical system of full-automatic biochemical analyzer Download PDF

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Publication number
CN102539346A
CN102539346A CN2011104177191A CN201110417719A CN102539346A CN 102539346 A CN102539346 A CN 102539346A CN 2011104177191 A CN2011104177191 A CN 2011104177191A CN 201110417719 A CN201110417719 A CN 201110417719A CN 102539346 A CN102539346 A CN 102539346A
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China
Prior art keywords
light
optical system
light source
cuvette
full
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Application number
CN2011104177191A
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Chinese (zh)
Inventor
梁桂秋
胡欣
赵坤耀
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SHENZHEN GLORY MEDICAL CO Ltd
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SHENZHEN GLORY MEDICAL CO Ltd
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Priority to CN2011104177191A priority Critical patent/CN102539346A/en
Publication of CN102539346A publication Critical patent/CN102539346A/en
Pending legal-status Critical Current

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Abstract

The invention discloses an optical system of a full-automatic biochemical analyzer, which relates to the technical field of the full-automatic biochemical analyzers and solves the technical defects of large consumption of reagents and large deviation of detection results in the optical system of the traditional full-automatic biochemical analyzer. The optical system comprises a light source light path and a rear light path system. The optical system is characterized in that: the light source light path comprises an electric light source and a collimator lens I for focusing light beams generated by the electric light source into a point light source and enabling the point light source to pass through a cuvette; the rear light path system comprises a collimator lens II, a flat-field holographic concave grating for splitting light, and a photoelectric array detector for receiving and converting monochromatic light produced after light splitting of the flat-field holographic concave grating into a voltage signal. The optical system of the full-automatic biochemical analyzer is simple in structural design and low in reagent consumption amount in comparison with a way that the light beam is directly used by the traditional light path in a front light splitting way or in a rear light splitting way.

Description

A kind of optical system of automatic clinical chemistry analyzer
Technical field
The present invention relates to the automatic clinical chemistry analyzer technical field, be specifically related to the architecture advances aspect of the optical system of automatic clinical chemistry analyzer.
Background technology
Automatic clinical chemistry analyzer is an instrument of measuring certain particular chemical composition in the body fluid according to the photoelectric colorimetry principle; Because its measuring speed is fast, accuracy is high, the consumption amount of reagent is few; Become clinical most important equipment; Be mainly used in various body fluid such as blood to human body, urine and carry out biochemical analysis and record data,, thereby be used widely in hospitals at different levels, epidemic prevention station, family planning service station at present so that scientific basis is provided for diagnosis and definite patient's state of an illness.
The automatic clinical chemistry analyzer of beam splitting system was progressively eliminated before the optical system of traditional automatic clinical chemistry analyzer adopted.Conventional back beam splitting system Biochemical Analyzer light path generally adopts the wedge type light beam through the reaction cuvette, through assemblies such as focus lamp, slits, on photometer, is dispersed into different wave length to polychromatic light again; The reagent that the shortcoming part of this mode is to detect use consumes bigger than normal, and in the conduction of light path, can produce light signal decay to a certain degree, finally influences testing result.
Summary of the invention
In sum, the optical system reagent consumption that fundamental purpose of the present invention is to solve existing automatic clinical chemistry analyzer is big, the technological deficiency that the testing result deviation is big, and the optical system of a kind of automatic clinical chemistry analyzer that proposes.
For solving technological deficiency proposed by the invention; The technical scheme that adopts: a kind of optical system of automatic clinical chemistry analyzer; Include to cuvette light source light path that photoelectric colorimetry measures required light source and the back light path system that is used for the light beam through cuvette after participating in accomplishing chrominance response at cuvette is detected are provided, it is characterized in that: described light source light path includes electric light source and with being used for the light beam that electric light source produces is focused into behind the pointolite collimator lens I through cuvette; Described back photosystem include be used for to the anaclasis through cuvette be reduced into get into the collimator lens I before identical light beam the collimator lens II be used for the light beam that collimation device lens II reflects and carry out the flat holographic concave gratings of beam split, and be used for the monochromatic light after the flat holographic concave gratings beam split is received the photovoltaic array detecting device that converts voltage signal to.
Technical scheme as the present invention being done further limit includes:
Described flat holographic concave gratings adopts and becomes spacing curved slot concave grating.
Described photovoltaic array detecting device includes more than two and changes the receiver that produces little electric current according to the light signal that receives; Be used for little current conversion that receiver produces is become the high impedance high gain operational amplifier of voltage signal and amplification; And is connected 16 high-precision AD converting systems of the voltage signal of reception amplification with the high impedance high gain operational amplifier through shielded cable.
Described flat holographic concave gratings branch 12 wavelength that shed are respectively the monochromatic light of 340nm, 380nm, 405nm, 450nm, 480nm, 505nm, 546nm, 570nm, 600nm, 660nm, 700nm and 750nm.
The present invention compared with prior art has following advantage and beneficial effect:
(1) structural design of the present invention is simple, and the optical axis of light path basically all is on same the straight line.
(2) light beam is become pointolite through cuvette, directly compare, can practice thrift reagent, reduce consuming through the cuvette method with traditional light beam.
(3) the change spacing curved slot concave grating that utilizes the holographic recording technology to obtain has the ability of remarkable program for correcting phase difference, and flat holographic concave gratings can realize taking into account flat field and improve resolution.
(4) conduction of light signal adopts optical fiber to accomplish, and realizes electromagnetic wave is eliminated the interference of signal and the decay in the signal transduction process fully, makes signal reach undamped, has improved measuring accuracy dramatically.
Description of drawings
Fig. 1 is a block diagram of the present invention;
Fig. 2 is a structural representation of the present invention.
Embodiment
Below will combine accompanying drawing, the preferred embodiments of the present invention will be carried out detailed description; Should be appreciated that preferred embodiment has been merely explanation the present invention, rather than in order to limit the present invention.
Shown in seeing figures.1.and.2, the present invention includes by two parts of light source light path and back light path system and form.The light source light path is used for providing photoelectric colorimetry to measure required light source to cuvette, and its main composition parts are: electric light source 1 and collimator lens I 2; Said electric light source 1 is preferably halogen tungsten lamp, and the light beam that halogen tungsten lamp produces light signal is transmitted in the collimator lens I 2, focuses on through 2 refractions of collimator lens I to become pointolite, and this pointolite is participated in chrominance response at 3 places, cuvette position of automatic clinical chemistry analyzer; It is that the semipermanent extraordinary UV plastics of 6mm monomer are processed that described cuvette adopts diameter.Back light path system is used for the light beam through cuvette after participating in accomplishing chrominance response at cuvette is detected, and its main composition parts are: collimator lens II 4, flat holographic concave gratings 6 and photovoltaic array detecting device 7; Said collimator lens II 4 is used for the light beam through cuvette is reduced into original beam; Said flat holographic concave gratings 6 adopts and becomes spacing curved slot concave grating; Flat holographic concave gratings 6 is mainly used in beam split, divides 12 wavelength that shed to be respectively the monochromatic light of 340nm, 380nm, 405nm, 450nm, 480nm, 505nm, 546nm, 570nm, 600nm, 660nm, 700nm and 750nm; Said photovoltaic array detecting device 7 includes 12 receiver, high impedance high-gain amplifier 5 and 16 high-precision AD converting systems of changing to produce little electric current according to the light signal that receives; Each receiver disperses the monochromatic optical window in back corresponding with a flat holographic concave gratings 6; Little electric current that receiver produces converts to voltage signal by each corresponding high impedance high gain operational amplifier 5 and amplifies, and the voltage signal conductively-closed cable that has amplified is sent to 16 high-precision AD converting systems.
According to above-mentioned said, the present invention is followed successively by along the structure of the direction whole optical path that light advances: electric light source 1, collimator lens I2, cuvette 3, collimator lens II4, flat holographic concave gratings 6 and photodiode array detector 7.The above is the preferred embodiments of the present invention, is not limited to the present invention, and obviously, those skilled in the art can carry out various changes and modification and not break away from the spirit and scope of the present invention the present invention.Like this, belong within the scope of claim of the present invention and equivalent technologies thereof if novel these of this adaptation are revised with modification, then the present invention also is intended to comprise these changes and modification interior.

Claims (4)

1. the optical system of an automatic clinical chemistry analyzer; Include to cuvette light source light path that photoelectric colorimetry measures required light source and the back light path system that is used for the light beam through cuvette after participating in accomplishing chrominance response at cuvette is detected are provided, it is characterized in that: described light source light path includes electric light source and with being used for the light beam that electric light source produces is focused into behind the pointolite collimator lens I through cuvette; Described back photosystem includes the collimator lens II that is used for the refraction of optical beam through cuvette is reduced into the light beam before identical with getting into the collimator lens I; Be used for the light beam that collimation device lens II reflects and carry out the flat holographic concave gratings of beam split, and be used for the monochromatic light after the flat holographic concave gratings beam split is received the photovoltaic array detecting device that converts voltage signal to.
2. the optical system of a kind of automatic clinical chemistry analyzer according to claim 1 is characterized in that: described flat holographic concave gratings employing change spacing curved slot concave grating.
3. the optical system of a kind of automatic clinical chemistry analyzer according to claim 1; It is characterized in that: described photovoltaic array detecting device includes more than two and changes the receiver that produces little electric current according to the light signal that receives; Be used for little current conversion that receiver produces is become the high impedance high gain operational amplifier of voltage signal and amplification; And is connected 16 high-precision AD converting systems of the voltage signal of reception amplification with the high impedance high gain operational amplifier through shielded cable.
4. the optical system of a kind of automatic clinical chemistry analyzer according to claim 1 is characterized in that: described flat holographic concave gratings branch 12 wavelength that shed are respectively the monochromatic light of 340nm, 380nm, 405nm, 450nm, 480nm, 505nm, 546nm, 570nm, 600nm, 660nm, 700nm and 750nm.
CN2011104177191A 2011-12-14 2011-12-14 Optical system of full-automatic biochemical analyzer Pending CN102539346A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108180950A (en) * 2018-03-27 2018-06-19 上海科华实验系统有限公司 Examine biochemical reaction container quality detection system and method
CN110261633A (en) * 2019-07-16 2019-09-20 江南大学 A kind of thrombus analyzer and thrombus analyzer system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60253853A (en) * 1984-05-30 1985-12-14 Toshiba Corp Optical system of automatic analyer
CN1808099A (en) * 2005-12-21 2006-07-26 沈阳东软医疗系统有限公司 Optical system of spectrophotometer of full-automatic biochemical analyzer
CN101482572A (en) * 2008-01-11 2009-07-15 株式会社东芝 Automatic analysis apparatus and automatic analysis method
CN202393698U (en) * 2011-12-14 2012-08-22 深圳市尚荣医疗股份有限公司 Optical system for full-automatic biochemical analyzer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60253853A (en) * 1984-05-30 1985-12-14 Toshiba Corp Optical system of automatic analyer
CN1808099A (en) * 2005-12-21 2006-07-26 沈阳东软医疗系统有限公司 Optical system of spectrophotometer of full-automatic biochemical analyzer
CN101482572A (en) * 2008-01-11 2009-07-15 株式会社东芝 Automatic analysis apparatus and automatic analysis method
CN202393698U (en) * 2011-12-14 2012-08-22 深圳市尚荣医疗股份有限公司 Optical system for full-automatic biochemical analyzer

Non-Patent Citations (1)

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Title
蔡红星 等: "CCD光纤光谱仪结构研究", 《电子测试》, no. 8, 31 December 2007 (2007-12-31) *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108180950A (en) * 2018-03-27 2018-06-19 上海科华实验系统有限公司 Examine biochemical reaction container quality detection system and method
CN108180950B (en) * 2018-03-27 2024-03-19 上海科华实验系统有限公司 System and method for detecting quality of biochemical reaction container
CN110261633A (en) * 2019-07-16 2019-09-20 江南大学 A kind of thrombus analyzer and thrombus analyzer system

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Application publication date: 20120704