CN103181398A - Insecticidal composition containing tolfenpyradn and profenofos and application thereof - Google Patents
Insecticidal composition containing tolfenpyradn and profenofos and application thereof Download PDFInfo
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- CN103181398A CN103181398A CN2011104569751A CN201110456975A CN103181398A CN 103181398 A CN103181398 A CN 103181398A CN 2011104569751 A CN2011104569751 A CN 2011104569751A CN 201110456975 A CN201110456975 A CN 201110456975A CN 103181398 A CN103181398 A CN 103181398A
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- pesticidal combination
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Abstract
The invention belongs to a pesticide field, and discloses an insecticidal composition containing tolfenpyradn and profenofos and applications thereof. Tolfenpyradn and profenofos are used as main effective components of the insecticidal composition, wherein the weight ratio of tolfenpyradn to profenofos is 0.1-80:0.5-80. The insecticidal composition has high synergic effect, overcomes and delays insecticide resistance of pests, has advantages of fast insecticidal speed, long persistent period and low cost, and has a higher obvious control effect than a single dose thereof does. The insecticidal composition of the invention is used for controlling Lepidoptera, homoptera, thysanoptera or mite pests, particularly lepidoptera diamondback moth, cotton bollworm, beet armyworm, thrips and mite pests, and has a higher obvious control effect than a single dose thereof does.
Description
Technical field
The invention belongs to pesticide field, be specifically related to a kind of Pesticidal combination and application thereof that contains Tolfenpyrad and Profenofos.
Background technology
Tolfenpyrad (Tolfenpyrad), chemical name: 4-chloro-3-ethyl-1-methyl-N-{[4-(4-methylphenoxy) phenyl]-methyl }-1H pyrazoles-5-carboxylic acid amides, be the off-white color pressed powder, density (25 ℃): 1.18g/cm, vapour pressure (25 ℃):＜5 * 10Pa.Solvability (25 ℃): water 0.037mg/L, n-hexane 7.41g/L, toluene 366g/L, methyl alcohol 59.6g/L.Distribution coefficient (n-octyl alcohol/water) (25 ℃): log Pow 5.61.Structural formula is:
The acute toxicity of Tolfenpyrad preparation is: rat oral LD50 102 (hero), 83 (female) mg/kg; Its mouse oral LD50104 (hero), 108 (female) mg/kg.Acute dermal toxicity is relatively low, to rat, mouse LD50 all＞2000mg/kg.Lagophthalmos eyeball and skin there is moderate spread effect.
Tolfenpyrad is the novel pyrazole heterocyclic insecticidal/acaricidal agent of former Mitsubishi chemical company (its agricultural chemicals partly now belong to Japanese agricultural chemicals company) exploitation, its main mechanism is the oxidative phosphorylation that stops insect, also has the ovum of killing, presses down food, suppresses to lay eggs and bactericidal action.
Profenofos (profenofos) has another name called bromine chlorine phosphorus, many worms phosphorus, and chemical name is: O-(4-bromo-2-chlorphenyl)-O-ethyl-S-propyl group-thiophosphate is broad-spectrum organophosphorous pesticide, has quick-acting.At plant leaf blade permeability is preferably arranged.Its mechanism of action is to suppress cholinesterase in the insect bodies.Structural formula is:
Former medicine is light yellow liquid, tool is garlicky, 100 ℃/1.80Pa of boiling point, vapour pressure 1.24 * 10 ∧ (4) Pa (25 ℃) density 1.455 (20 ℃), KowlogP=4.44, solvability water 28mg/L (25 ℃) is with most immiscible organic solvent, more stable under neutral and little sour condition, unstable in the alkaline environment.This kind have tag, stomach toxicity and stifling three kinds of modes of action, its insecticidal spectrum is wide, toxicity is lower, efficient equally to the ground soil insect, it is the desirable insecticide of control grain, fruit tree, vegetables and other economic crops insect pests, control efficiency to underground insect is particularly outstanding, is particularly suitable for being applied to the production of pollution-free vegetable.
But diamond-back moth, cotton bollworm and thrips are under the condition of present long-term prescription, and resistance increases gradually, and the agent of agricultural chemicals list descends gradually to the effect of control of insect.The inventor finds that after deliberation the synergistic complex of agricultural chemicals is expanding prevention spectrum and the effective measures that improve preventive effect, still finds no the Pesticidal combination that closes Tolfenpyrad and Profenofos up to now.
Summary of the invention
The purpose of this invention is to provide a kind of Pesticidal combination that contains Tolfenpyrad and Profenofos.
Another object of the present invention provides the application of this Pesticidal combination.
The objective of the invention is to be achieved through the following technical solutions:
A kind of Pesticidal combination that contains Tolfenpyrad and Profenofos, this Pesticidal combination is main active ingredient with Tolfenpyrad and Profenofos, wherein, the weight ratio of Tolfenpyrad and Profenofos is 0.1～80: 0.5～80, be preferably 0.5～50: 2～50, more preferably 0.5～10: 4～30, preferred especially 1: 01～10.Effective ingredient is present in the composition with the synergy effective dose in this Pesticidal combination.
In Pesticidal combination of the present invention, the two gross weight percentage composition in this Pesticidal combination of Tolfenpyrad and Profenofos is 3%～80%.Be preferably 5%～55%, most preferably 10%～40%.
Pesticidal combination of the present invention is that the auxiliary agent that allows on main active ingredient and the agricultural chemicals is mixed with any one formulation with Tolfenpyrad and Profenofos, the preferred emulsion of described formulation, suspending agent, wetting powder, aqueous emulsion, microemulsion or water dispersion granule.
Auxiliary agent can adopt calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, polyoxyethylene polyoxy third rare block compound (as the newborn 33# of farming), polyoxyethylene nonylphenol ether, cyclohexanone, dimethylbenzene, solvent naphtha, water, antifreezing agent (as propane diols), deionized water etc.Above auxiliary agent can singly be used or and use.
The Pesticidal combination that contains Tolfenpyrad and Profenofos of the present invention is prevented and treated the application on the insecticidal materials of resistance Lepidoptera, Homoptera, thrips or mite pest in preparation, the preferably application on the insecticidal materials of one or more insects in preparation control diamond-back moth, cotton bollworm, beet armyworm or thrips, the further application on the insecticidal materials of preferred one or more insects in preparation control vegetables diamond-back moth, cotton bollworm.
Beneficial effect of the present invention compared with prior art: (1) is compared with single agent, the control of said composition antagonism lepidoptera pest such as diamond-back moth and thrips insect thrips etc. has obvious synergistic function, overcome and delayed pest resistance to insecticide, the expanding prevention spectrum, desinsection speed is fast, has obviously improved control efficiency; (2) reduce control recruitment, drug cost; (3) alternative high-toxic pesticide; (4) have concurrently quick-acting and long-acting; (5) compare with the agent of Profenofos list with Tolfenpyrad, produce and the use cost reduction; (6) suppress lepidoptera pest, Homoptera, thrips and mite pest to the resistance enhancing of agricultural chemicals, its effect is used apparently higher than its single agent.
Embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1:
Taking by weighing Tolfenpyrad, Profenofos, to adopt the conventional formulation method to be mixed with main active ingredient weight percentage by different proportion be 30% Tolfenpyrad Profenofos missible oil.Concrete ratio sees Table 1,2.
Adopt infusion process to carry out indoor synergy biologicall test, selecting the resistance diamond-back moth is target pest, and every processing repeats 3 times, and every concentration is handled 60, calculates toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism diamond-back moth with probability value method
50, use LC
50Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, the results are shown in Table 1:
The toxicity test of the composite and single agent antagonism of table 1 Tolfenpyrad and Profenofos diamond-back moth
As shown in Table 1, Tolfenpyrad and Profenofos are composite, and co-toxicity coefficient shows good synergistic effects all greater than 120.
Employing is soaked the leaf dip method and is carried out indoor synergy biologicall test, and the selection resistant bollworm is target pest, and every processing repeats 3 times, calculates toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism cotton bollworm with probability value method
50, use LC
50Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, the results are shown in Table 2:
The toxicity test of the composite and single agent antagonism of table 2 Tolfenpyrad and Profenofos cotton bollworm
As shown in Table 2, Tolfenpyrad and Profenofos are composite, and the co-toxicity coefficient of cotton bollworm all greater than 120, is shown good synergistic effects.
Embodiment 2:
Take by weighing 2g Tolfenpyrad, 18g Profenofos, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphate 3g, farming breast 33
#2g, alkylphenol polyoxyethylene 1g, cyclohexanone 10g adds water to 100g.The method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 20% Tolfenpyrad Profenofos microemulsion.
Embodiment 2 is prevented and treated the vegetables diamond-back moth test of pesticide effectiveness, the contrast medicament is 40% Profenofos EC (missible oil) and 15% Tolfenpyrad EC, extension rate according to 3 li of forms dilutes, and looks into the result of 3 days, 7 days, 14 days and 28 days behind the medicine, and result sees Table 3:
Table 3: the composite field test results to the vegetables diamond-back moth of Tolfenpyrad Profenofos
Field efficacy is the result show, Tolfenpyrad Profenofos composition antagonism diamond-back moth has good control efficiency, and control efficiency all is better than the effect that single agent kind is better than direct each Dan Pin of while.
Embodiment 2 is prevented and treated cotton cotton bollworm field medicine effect test, the contrast medicament is 40% Profenofos EC (missible oil) and 15% Tolfenpyrad EC, dilutes according to the extension rate of table 4 li, looks into behind the medicine 3 days, the result of 7 days, 14 days and 28 days, result sees Table 4:
Table 4: the composite field test results to cotton bollworm of Tolfenpyrad Profenofos
Field efficacy is the result show, Tolfenpyrad Profenofos composition antagonism cotton bollworm has good control efficiency, and control efficiency all is better than the effect that single agent kind is better than direct each Dan Pin of while.
Measure through indoor synergism test and to show: by composite dose of Tolfenpyrad and Profenofos cotton cotton bollworm and vegetables diamond-back moth are all had significant synergistic insecticidal action; Field control effectiveness test equally also shows the composite dose of effect that the insecticidal effect of cotton cotton bollworm and diamond-back moth all is significantly higher than corresponding single agent agricultural chemicals that the present invention is all.
Embodiment 3:
Take by weighing 5g Tolfenpyrad, 50g Profenofos, phenethyl phenol polyethenoxy ether phosphate 3g, farming breast 33
#2g, alkylphenol polyoxyethylene 1g, dimethylbenzene 13g adds water to 100g.The method that above raw material is prepared aqueous emulsion routinely drops into the mixing kettle high speed mixes, and forms main active ingredient weight percentage and be 55% Tolfenpyrad Profenofos aqueous emulsion.
Embodiment 4:
Take by weighing 1g Tolfenpyrad, 5g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, dimethylbenzene to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 6% Tolfenpyrad Profenofos missible oil.
Embodiment 5:
Take by weighing 50g Tolfenpyrad, 20g Profenofos, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 70% Tolfenpyrad Profenofos missible oil.
Embodiment 6:
Take by weighing 2g Tolfenpyrad, 40g Profenofos, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 42% Tolfenpyrad Profenofos missible oil.
Embodiment 7:
Take by weighing 0.2g Tolfenpyrad, 50g Profenofos, calcium dodecyl benzene sulfonate 9g, phenethyl phenol polyethenoxy ether 8g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 50.2% Tolfenpyrad Profenofos missible oil.
Embodiment 8:
Take by weighing 5g Tolfenpyrad, 0.5g Profenofos, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 5.5% Tolfenpyrad Profenofos missible oil.
Embodiment 9:
Take by weighing 5g Tolfenpyrad, 30g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 35% Tolfenpyrad Profenofos missible oil.
Embodiment 10:
Take by weighing 20g Tolfenpyrad, 5g Profenofos, calcium dodecyl benzene sulfonate 7g, phenethyl phenol polyethenoxy ether 9g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 25% Tolfenpyrad Profenofos missible oil.
Embodiment 11:
Take by weighing 30g Tolfenpyrad, 12g Profenofos, sodium lignin sulfonate 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, water complements to 100g, and the main active ingredient weight percentage of formation is 42% Tolfenpyrad Profenofos suspending agent under the effect of sand mill.
Embodiment 12:
Take by weighing 2g Tolfenpyrad, 5g Profenofos, sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, diatomite is to 100g, and it is 7% Tolfenpyrad Profenofos water dispersion granule that above raw material is formed main active ingredient weight percentage by the water dispersible granular agent method.
Embodiment 13:
Take by weighing 50g Tolfenpyrad, 3g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 53% Tolfenpyrad Profenofos missible oil.
Embodiment 14:
Take by weighing 2g Tolfenpyrad, 18g Profenofos, sodium lignin sulfonate 10g, Negel 2g, add to 100g with diatomite, above raw material is mixed in micronizer, form main active ingredient weight percentage and be 20% Tolfenpyrad Profenofos wetting powder.
Embodiment 15:
Take by weighing 7g Tolfenpyrad, 70g Profenofos, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, dimethylbenzene are to 100g.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms main active ingredient weight percentage and be 77% Tolfenpyrad Profenofos missible oil.
Embodiment 16:
Take by weighing 60g Tolfenpyrad, 5g Profenofos, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 13g, it is 65% Tolfenpyrad Profenofos water dispersible granules that above raw material is formed main active ingredient weight percentage by the water dispersible granular agent method.
Claims (10)
1. a Pesticidal combination that contains Tolfenpyrad and Profenofos is characterized in that this Pesticidal combination is main active ingredient with Tolfenpyrad and Profenofos, and wherein, the weight ratio of Tolfenpyrad and Profenofos is 0.1～80: 0.5～80.
2. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 1, the weight ratio that it is characterized in that described Tolfenpyrad and Profenofos is 0.5～50: 2～50.
3. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 2, the weight ratio that it is characterized in that described Tolfenpyrad and Profenofos is 0.5～10: 4～30, preferred 1: 0.1～10.
4. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 1 is characterized in that the two gross weight percentage composition in this Pesticidal combination of Tolfenpyrad and Profenofos is 3%～80%.
5. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 4 is characterized in that the two gross weight percentage composition in this Pesticidal combination of Tolfenpyrad and Profenofos is 5%～55%.
6. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 4 is characterized in that the two gross weight percentage composition in this Pesticidal combination of Tolfenpyrad and Profenofos is 10%～40%.
7. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 1 is characterized in that this Pesticidal combination is that the auxiliary agent that allows on main active ingredient and the agricultural chemicals is mixed with any one formulation with Tolfenpyrad and Profenofos.
8. the Pesticidal combination that contains Tolfenpyrad and Profenofos according to claim 7 is characterized in that described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule.
9. the described application of Pesticidal combination on the insecticidal materials of preparation control Lepidoptera, Homoptera, thrips or mite pest that contains Tolfenpyrad and Profenofos of claim 1.
10. the application of Pesticidal combination on preparing the insecticidal materials of preventing and treating one or more insects in diamond-back moth, cotton bollworm, beet armyworm or the thrips that contains Tolfenpyrad and Profenofos according to claim 9, the preferably application on the insecticidal materials of one or more insects in preparation control vegetables diamond-back moth, cotton bollworm.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106305799A (en) * | 2016-08-23 | 2017-01-11 | 赖丰光 | Profenofos pesticide composite containing insecticidal plant |
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| JP2006131516A (en) * | 2004-11-04 | 2006-05-25 | Nippon Nohyaku Co Ltd | Pest control agent composition and method for use thereof |
| CN101658178A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Synergistic insecticidal composition |
| CN101690494A (en) * | 2009-07-15 | 2010-04-07 | 深圳诺普信农化股份有限公司 | Synergistic pesticide composition and use thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006131516A (en) * | 2004-11-04 | 2006-05-25 | Nippon Nohyaku Co Ltd | Pest control agent composition and method for use thereof |
| CN101690494A (en) * | 2009-07-15 | 2010-04-07 | 深圳诺普信农化股份有限公司 | Synergistic pesticide composition and use thereof |
| CN101658178A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Synergistic insecticidal composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106305799A (en) * | 2016-08-23 | 2017-01-11 | 赖丰光 | Profenofos pesticide composite containing insecticidal plant |
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Application publication date: 20130703 |