CN103168783B - Azadirachtin emulsion composition and preparation method of azadirachtin emulsion composition - Google Patents
Azadirachtin emulsion composition and preparation method of azadirachtin emulsion composition Download PDFInfo
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- CN103168783B CN103168783B CN201110434202.3A CN201110434202A CN103168783B CN 103168783 B CN103168783 B CN 103168783B CN 201110434202 A CN201110434202 A CN 201110434202A CN 103168783 B CN103168783 B CN 103168783B
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- nimbin
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- antifreeze
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Abstract
The invention discloses an azadirachtin emulsion composition and a preparation method of the azadirachtin emulsion composition. The azadirachtin emulsion composition consists of azadirachtin, an emulsifying agent, a penetrating agent, a stabilizing agent, an antifreeze, a cosolvent and a solvent, wherein the content (weight) of all the components are as follows: 0.3%-1% of the azadirachtin, 8%-12% of the emulsifying agent, 5%-8% of the penetrating agent, 5%-10% of the stabilizing agent, 5%-10% of the antifreeze, 5%-10% of the cosolvent and the rest of the solvent. Due to the synergistic effects of the components of the azadirachtin emulsion composition, the azadirachtin can be sufficiently dissolved. In addition, as the plant oil solvent is adopted, the toxicity of the solvent is greatly reduced, and an obtained preparation is environment-friendly and safe.
Description
Technical field
The present invention relates to nimbin emulsion composition and method of making the same.
Background technology
Missible oil is to configure with emulsifier the transparence liquid processing by water-fast former medicine, organic solvent-benzene, dimethylbenzene etc., and normal temperature lower seal is deposited 2 years generally can be not muddy, layering and precipitation, is added to the water the opaque emulsion of rapid dispersed one-tenth.The feature of missible oil is: drug effect is high, uses conveniently, and character is more stable.Because the history of missible oil is longer, there is ripe process technology, so wide in variety, output is large, applied range remain at present a main formulation of agricultural chemicals, but it in use exists very large problem.
The key of missible oil problem is solvent, and the solvent that at present China's missible oil uses is mainly volatile light aromatic solvent, this solvent has that toxicity is higher, inflammable, long half time, to shortcomings such as environmental influence are large.In addition, also use more toxicity higher or have the solvent of teratogenesis in some other formulation, as methyl alcohol, dimethyl formamide etc., therefore, if can use the solvent that relative toxicity is lower, safety is higher, missible oil is still a kind of good formulation.
Nimbin emulsion is a kind of agricultural chemicals that adopts missible oil formulation, and wherein nimbin is a kind of plant resource active substance that has the effect of multiple poisoning insect, is present in and prints in Melia seal chinaberry plant species core and leaf.Nimbin is because in water, easily decomposition water baseization product development difficulty is larger, and missible oil will be the main formulation of nimbin at present.Therefore, how the formulation of nimbin emulsion being optimized, particularly how various auxiliary agent formulations in missible oil being improved, make more Environmental Safety of nimbin preparation, is technical problem urgently to be resolved hurrily.
Summary of the invention
The object of this invention is to provide a kind of nimbin emulsion composition of Environmental Safety more.
According to a first aspect of the invention, provide a kind of nimbin emulsion composition.Said composition is by nimbin, emulsifier, bleeding agent, stabilizing agent, antifreeze, cosolvent and solvent composition, and wherein the content of each component (weight) is as follows:
Nimbin: 0.3%-1%; Emulsifier: 8%-12%; Bleeding agent: 5%-8%; Stabilizing agent: 5%-10%; Antifreeze: 5%-10%; Cosolvent: 5%-10%; Solvent: surplus.
Solvent can be selected from the vegetable oil such as volatile oil extracted from eucalyptus' leaves or twigs, turpentine-based vegetable oil, neem oil and Jatropha curcas oil.
Emulsifier can be selected from sorbitan monostearate, polyoxyethylene sorbitan ether monoleate and fatty alcohol-polyoxyethylene ether.
Bleeding agent can be selected from NP class non-ionic surface active agent, AEO class non-ionic surface active agent and organosilicon.
Stabilizing agent can be selected from 2,6 BHTs, sorbic acid, polyethylene glycol glycidol ether, cresyl glycidyl ether, butyl glycidyl ether and two (2,2,6,6-tetramethyl-piperidyl) sebacate.
Antifreeze can be selected from ethylene glycol, glycerine and sorbierite.
Cosolvent can be selected from ethanol and dibasic ester.
The preparation method of above-mentioned nimbin emulsion composition is provided according to a further aspect in the invention.The method comprises:
Fully dissolve nimbin with cosolvent;
Then add 1/3 of emulsifier and solvent total amount to carry out fully emulsified;
Add again antifreeze and stabilizing agent and be uniformly mixed; And
Finally add remaining solvent and stir.
By the prepared nimbin emulsion composition of method of the present invention, due to the mutual synergistic effect between its component, thereby make nimbin can be able to abundant dissolving.In addition, owing to having adopted vegetable oil solvent, thereby greatly reduce solvent toxicity, made gained preparation Environmental Safety more.
Embodiment
Describe nimbin emulsion composition and method of making the same of the present invention in detail below in conjunction with specific embodiment.
Nimbin emulsion composition of the present invention is by nimbin, emulsifier, bleeding agent, stabilizing agent, antifreeze, cosolvent and solvent composition, and its preparation method is as follows:
Fully dissolve nimbin with cosolvent;
Then add 1/3 of emulsifier and solvent total amount to carry out fully emulsified;
Add again antifreeze and stabilizing agent and be uniformly mixed; And
Finally add remaining solvent and stir 0.5 hour-1 hour.
Provide several specific embodiments of nimbin emulsion composition of the present invention below.
nimbin emulsion composition 1(ratio of each component is weight ratio)
Nimbin: (0.3%);
Emulsifier: sorbitan monostearate (8%);
Bleeding agent: alkylphenol polyoxyethylene (5%);
Stabilizing agent: 2,6 BHTs (5%);
Antifreeze: ethylene glycol (5%);
Cosolvent: ethanol (5%); With
Solvent: volatile oil extracted from eucalyptus' leaves or twigs (surplus).
nimbin emulsion composition 2(ratio of each component is weight ratio)
Nimbin: (0.5%);
Emulsifier: polyoxyethylene dehydration mountain alcohol ether monoleate (10%);
Bleeding agent: organosilicon (8%);
Stabilizing agent: sorbic acid (8%);
Antifreeze: glycerine (8%);
Cosolvent: dibasic ester (10%); With
Solvent: turpentine-based vegetable oil (surplus).
nimbin emulsion composition 3(ratio of each component is weight ratio)
Nimbin: (1%);
Emulsifier: fatty alcohol-polyoxyethylene ether (12%);
Bleeding agent: alkylphenol polyoxyethylene (5%);
Stabilizing agent: cresyl glycidyl ether (10%);
Antifreeze: sorbierite (10%);
Cosolvent: ethanol (8%); And
Solvent: Jatropha curcas oil (surplus).
It will be appreciated by those skilled in the art that above-mentioned specific embodiment is only for explaining the present invention but not for making any restriction to it.Although the nimbin using in the present invention can be purification form, but also can adopt other form for example to contain seal chinaberry powder or the mimbin extract of nimbin active ingredient, need only the weight content of nimbin contained in the nimbin emulsion composition of final preparation between 0.3% to 1%.For example, the seal chinaberry powder (this seal chinaberry powder contains 41% nimbin effective active composition) that the nimbin that in above-mentioned nimbin emulsion composition 1, weight ratio is 3% can be also 0.72% by weight ratio substitutes and provides.
Claims (4)
1. a nimbin emulsion composition, the weight content of each component is as follows:
Nimbin: 0.3%; Emulsifier: 8%; Bleeding agent: 5%; Stabilizing agent: 5%; Antifreeze: 5%; Cosolvent: 5%; Solvent: surplus; Wherein
Emulsifier is sorbitan monostearate;
Bleeding agent is alkylphenol polyoxyethylene;
Stabilizing agent is 2,6 BHTs;
Antifreeze is ethylene glycol;
Cosolvent is ethanol;
Solvent is volatile oil extracted from eucalyptus' leaves or twigs.
2. a nimbin emulsion composition, the weight content of each component is as follows:
Nimbin: 0.5%; Emulsifier: 10%; Bleeding agent: 8%; Stabilizing agent: 8%; Antifreeze: 8%; Cosolvent: 10%; Solvent: surplus; Wherein
Emulsifier is polyoxyethylene dehydration mountain alcohol ether monoleate;
Bleeding agent is organosilicon;
Stabilizing agent is sorbic acid;
Antifreeze is glycerine;
Cosolvent is dibasic ester;
Solvent is turpentine-based vegetable oil.
3. a nimbin emulsion composition, the weight content of each component is as follows:
Nimbin: 1%; Emulsifier: 12%; Bleeding agent: 5%; Stabilizing agent: 10%; Antifreeze: 10%; Cosolvent: 8%; Solvent: surplus; Wherein
Emulsifier is fatty alcohol-polyoxyethylene ether;
Bleeding agent is alkylphenol polyoxyethylene;
Stabilizing agent is cresyl glycidyl ether;
Antifreeze is sorbierite;
Cosolvent is ethanol;
Solvent is Jatropha curcas oil.
4. according to the preparation method of the nimbin emulsion composition described in any one in claim 1-3, comprising:
Fully dissolve nimbin with cosolvent;
Then add 1/3 of emulsifier and solvent total amount to carry out fully emulsified;
Add again antifreeze and stabilizing agent and be uniformly mixed; And finally add remaining solvent and stir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110434202.3A CN103168783B (en) | 2011-12-22 | 2011-12-22 | Azadirachtin emulsion composition and preparation method of azadirachtin emulsion composition |
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| CN201110434202.3A CN103168783B (en) | 2011-12-22 | 2011-12-22 | Azadirachtin emulsion composition and preparation method of azadirachtin emulsion composition |
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| CN103168783A CN103168783A (en) | 2013-06-26 |
| CN103168783B true CN103168783B (en) | 2014-09-03 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103766335A (en) * | 2014-01-27 | 2014-05-07 | 崔建州 | Grease and wax dissolving penetrating agent |
| CN104255747A (en) * | 2014-09-02 | 2015-01-07 | 石家庄市青冠化工有限公司 | Environment-friendly azadirachtin missible oil and preparation method thereof |
Citations (8)
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| US5124349A (en) * | 1989-06-26 | 1992-06-23 | W. R. Grace & Co.-Conn. | Storage stable azadirachtin formulation |
| CN1411724A (en) * | 2002-10-09 | 2003-04-23 | 华南农业大学 | Nimbin and thiazinedone mixed pesticide preparation |
| CN1112106C (en) * | 2000-04-27 | 2003-06-25 | 华南农业大学 | Plant-type nimbin insecticide |
| US6811790B1 (en) * | 2000-03-27 | 2004-11-02 | E.I.D. Parry (India) Ltd. | Storage stable pesticide formulations containing azadirachtin |
| CN100418418C (en) * | 2005-06-24 | 2008-09-17 | 福建省泉州德盛农药有限公司 | Pesticide auxiliary agent |
| CN101606517A (en) * | 2009-07-27 | 2009-12-23 | 深圳诺普信农化股份有限公司 | A kind of farm chemical emulsion preparation |
| CN1948328B (en) * | 2006-10-26 | 2010-05-12 | 华南农业大学 | Methyl amine abamectin acylate and its preparation method and application |
| CN101703076A (en) * | 2009-09-22 | 2010-05-12 | 成都绿金高新技术股份有限公司 | Nimbin general oil solution |
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2011
- 2011-12-22 CN CN201110434202.3A patent/CN103168783B/en active Active
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| US5124349A (en) * | 1989-06-26 | 1992-06-23 | W. R. Grace & Co.-Conn. | Storage stable azadirachtin formulation |
| US5124349B1 (en) * | 1989-06-26 | 1998-10-20 | Grace W R & Co | Storage stable azadirachtin formulation |
| US6811790B1 (en) * | 2000-03-27 | 2004-11-02 | E.I.D. Parry (India) Ltd. | Storage stable pesticide formulations containing azadirachtin |
| CN1112106C (en) * | 2000-04-27 | 2003-06-25 | 华南农业大学 | Plant-type nimbin insecticide |
| CN1411724A (en) * | 2002-10-09 | 2003-04-23 | 华南农业大学 | Nimbin and thiazinedone mixed pesticide preparation |
| CN100418418C (en) * | 2005-06-24 | 2008-09-17 | 福建省泉州德盛农药有限公司 | Pesticide auxiliary agent |
| CN1948328B (en) * | 2006-10-26 | 2010-05-12 | 华南农业大学 | Methyl amine abamectin acylate and its preparation method and application |
| CN101606517A (en) * | 2009-07-27 | 2009-12-23 | 深圳诺普信农化股份有限公司 | A kind of farm chemical emulsion preparation |
| CN101703076A (en) * | 2009-09-22 | 2010-05-12 | 成都绿金高新技术股份有限公司 | Nimbin general oil solution |
Non-Patent Citations (1)
| Title |
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| 李晓芬.松脂基植物油：乳油农药的绿色新生.《农药市场信息》.2011,(第20期),参见第35-36页. * |
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Inventor after: Ding Chengfeng Inventor after: Li Fugen Inventor after: Liu Yan Inventor after: Huang Geng Inventor after: Wu Xuemin Inventor after: Zhang Yong Inventor after: Zhu Xincheng Inventor before: Ma Jianju Inventor before: Huang Geng Inventor before: Ding Chengfeng Inventor before: Zhang Yong Inventor before: Liu Yan |
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Free format text: CORRECT: INVENTOR; FROM: MA JIANJU HUANG GENG DING CHENGFENG ZHANG YONG LIU YAN TO: DING CHENGFENG LI FUGEN LIU YAN HUANG GENG WU XUEMIN ZHANG YONG ZHU XINCHENG |
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Effective date of registration: 20161228 Address after: 611500 Sichuan city of Chengdu province Qionglai city Linchiung fishing village (Linqiong Industrial Park) sing Patentee after: Chengdu Lujin Biological Science & Technology Co., Ltd. Address before: High tech Zone Gaopeng road in Chengdu city of Sichuan province 610041 No. 5 Technology Innovation Service Center Patentee before: Chengdu Greengold High-Tech Co., Ltd. |