CN103156996A

CN103156996A - Traditional Chinese medicine preparation for treating dilated myocarditis and preparation method thereof

Info

Publication number: CN103156996A
Application number: CN201110421410XA
Authority: CN
Inventors: 曾丽丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-12-14
Filing date: 2011-12-14
Publication date: 2013-06-19

Abstract

The invention relates to the technical field of traditional Chinese medicine, specifically to a traditional Chinese medicine preparation for treating dilated myocarditis and a preparation method thereof. The traditional Chinese medicine preparation is characterized by comprising the following bulk drugs by weight: 10 to 15 parts of raw rehmannia root, 5 to 12 parts of cochinchinese asparagus root, 6 to 12 parts of dwarf lilyturf tuber, 5 to 10 parts of red sage root, 5 to 12 parts of spine date seed, 5 to 12 parts of arborvitae seed, 5 to 10 parts of ginseng, 54 to 12 parts of Chinese magnoliavine fruit, 8 to 12 parts of Poria cocos, 5 to 12 parts of polygala root, 5 to 12 parts of figwort root, 5 to 12 parts of red sage root, 5 to 12 parts of cinnabar and 5 to 12 parts of balloonflower root. The above-mentioned components are weighed in proportion, crushed into 300-mesh fine powder, subjected to water decoction and condensation, granulated by a granulator and finally dried so as to prepare the traditional Chinese medicine preparation provided by the invention. The invention has the following beneficial effects: the preparation realizes treatment starting with an integral body of the heart, the liver, the spleen, the lung and the kidney based on a unique dialectical thinking mode of diagnosis and treatment of traditional Chinese medicine, has the functions of warming, benefiting, Qi rectifying, blood circulation invigorating and dampness repelling, carries out comprehensive recuperative medical care to eliminate symptoms and achieves the effect of simultaneous treatment of principal and subordinate symptoms.

Description

Chinese medicine preparation for the treatment of dilated cardiomyopathy inflammation and preparation method thereof

Technical field

The present invention relates to the Chinese medicine technical field, be specially Chinese medicine preparation for the treatment of dilated cardiomyopathy inflammation and preparation method thereof.

Background technology

The dilated cardiomyopathy inflammation is with cardiac dilatation, heart failure, and arrhythmia is main manifestations.Cardiac dilatation is the most common, the apex decreased loudness of first sound, due to relative mitral insufficiency, the apex of the heart often has systolic murmur, the apex audible is opened the phase noise once in a while, when heart failure increases the weight of, noise strengthens, and when heart failure alleviates, noise weakens or disappears, about 75% patient's audible third heart sound or fourth heart sound.10% patient's blood pressure increases, and in the time of may be with heart failure, to increase water-sodium retention relevant for Secretion of Catecholamine.After heart failure was controlled, it is normal that blood pressure recovers, and also has and deposit the hypertension patient.The person that heart failure thes occur, available heart tonifying, diuretic are not less than the available vasodilation of 12.7kpa (95mmHg) as systolic pressure.Arrhythmia person is arranged, can according to different arrhythmia, select medication, blood pressure person on the low side, but intravenous drip dopamine 5ug/min.Clinical symptoms can not be improved and biopsy turns out to be myocarditic patient, can try out the immunosuppressant of a course for the treatment of.The course of disease is short, and onset has heating person, also can try out hormone therapy.This patient cardiac muscle beta receptor density is lowered, and along with increasing the weight of of degree of heart failure, lowers also more obvious.In order to improve myocardium beta receptor density, improve the reactivity of cardiac muscle, available beta-blocker treatment.In case the generation heart failure, prognosis mala, 5 annual death rate 35%, 10 annual death rate 70%.It is " modern pestilence " that the physician of the U.S. likens it.Particularly developed country has all dropped into a large amount of manpowers and fund, is engaged in cardiopathic treatment research.All drop into a large amount of manpowers and fund, be engaged in treatment research.

The present invention adopts the multiple medicines coupling according to clinical experiment, and number medicine and use have warming function, tonification function, the function of regulating the flow of vital energy, blood circulation-promoting functions, dampness-removing function, medical treatment comprehensively, reach symptomatolytic purpose.

Summary of the invention

The present invention adopts that Chinese medicine has warm, tonification, regulates the flow of vital energy, invigorates blood circulation, damp eliminating, medical treatment, symptomatolytic function comprehensively, is obtaining effect aspect the treatment myocarditis, and concrete technical scheme is as follows:

One, the compatibility theory of Chinese medicine of the present invention

Take Radix Rehmanniae as monarch drug, enriching yin and nourishing kidney, blood enriching and dryness moistening; Radix Asparagi, Radix Ophiopogonis, Radix Salviae Miltiorrhizae replenishing YIN and removing heat; Semen Ziziphi Spinosae, the Semen Platycladi nourishing blood to tranquillize the mind; Assistant is with Radix Ginseng, Fructus Schisandrae Chinensis QI invigorating mind calming; Poria, the Radix Polygalae restoring normal coordination between the heart and kidney; Radix Scrophulariae, Radix Salviae Miltiorrhizae, Cinnabaris nourishing YIN to lower pathogenic fire, mind tranquilizing and the heart calming; At last with Radix Platycodonis as making medicine, medicine carrying is up.Be treatment heart kidney deficiency of YIN-blood, the prescription of mind uneasiness.

Two, the pbw of Chinese medicine preparation of the present invention is:

Radix Rehmanniae: 10-15 part, large winter; 5-12 part, Radix Ophiopogonis; 6-12 part, Radix Salviae Miltiorrhizae: 5-10 part, Semen Ziziphi Spinosae; 5-12 part,, Semen Platycladi 5-12 part,, Radix Ginseng: 5-10 part, Fructus Schisandrae Chinensis 54-12 part, Poria: 8-12 part, Radix Polygalae: 5-12 part, Radix Scrophulariae: 5-12 part, Radix Salviae Miltiorrhizae: 5-12 part, Cinnabaris: 5-12 part, Radix Platycodonis, 5-12 part.

The best prescription pbw of described Chinese medicine is: Radix Rehmanniae: 10 parts, and Radix Asparagi: 6 parts, Radix Ophiopogonis; 6 parts, Radix Salviae Miltiorrhizae: 6 parts, Semen Ziziphi Spinosae; 6 parts,, Semen Platycladi: 8 parts, Radix Ginseng: 6 parts, 6 parts of Fructus Schisandrae Chinensis, Poria: 6 parts, Radix Polygalae: 6 parts, Radix Scrophulariae: 8 parts, Radix Salviae Miltiorrhizae: 8 parts, Cinnabaris: 8 parts, Radix Platycodonis: 10 parts.

Three, the preparation method of Chinese medicine preparation of the present invention

The Chinese medicine preparation of making of the present invention is by said components and proportioning, is ground into 300 order fine powders, and every 100g medicated powder adds the decocting of 300ml to make condensed cream, by the granulator corning, and dry getting final product, every about 0.1-0.15g.

Four, clinical efficacy.

Scorching patient's 35 examples of dilated cardiomyopathy that certain hospital is accepted for medical treatment are divided into two groups at random:

Treat on the basis of conventional therapy for one group and be treatment group, patient's 18 examples are arranged; One group is adopted the conventional therapy matched group, patient's 17 examples is arranged.Treatment group produce effects 13 examples as a result, effective four examples, an invalid example, total effective rate is 94 percent; Effective ten examples of matched group produce effects, effective two examples, invalid five examples, total effective rate 70 percent, two groups of comparing differences have significance (P＜0.05), the left chamber diastole of two groups is the difference of phase internal diameter (LVDd), Left Ventricular Ejection Fraction (EF) and heart rate value variation not, has the significance conclusion to use in routine on the basis of Folium Digitalis Purpureae, diuretic, angiotensin converting enzyme inhibitor (ACEI) the dilated cardiomyopathy inflammation is had clinical therapeutic efficacy preferably.

The specific embodiment

Example 1:

Described Chinese medicine preparation mass ratio is divided into: Radix Rehmanniae: 10 parts, and Radix Asparagi: 6 parts, Radix Ophiopogonis; 6 parts, Radix Salviae Miltiorrhizae: 6 parts, Semen Ziziphi Spinosae; 6 parts, Semen Platycladi: 8 parts, Radix Ginseng: 6 parts, 6 parts of Fructus Schisandrae Chinensis, Poria: 6 parts, Radix Polygalae: 6 parts, Radix Scrophulariae: 8 parts, Radix Salviae Miltiorrhizae: 8 parts, Cinnabaris: 8 parts, Radix Platycodonis: 10 parts.

The Chinese medicine preparation of making of the present invention is by said components and proportioning, is ground into 400 order fine powders, and every 100g medicated powder adds the decocting of 300ml to make condensed cream, by the granulator corning, and dry getting final product, every about 0.1-0.15g.

Example 2:

Described Chinese medicine preparation mass ratio is divided into: Radix Rehmanniae: 12 parts, and Radix Asparagi: 5 parts, Radix Ophiopogonis; 5 parts, Radix Salviae Miltiorrhizae: 6 parts, Semen Ziziphi Spinosae; 6 parts, Semen Platycladi: 8 parts, Radix Ginseng: 6 parts, 6 parts of Fructus Schisandrae Chinensis, Poria: 6 parts, Radix Polygalae: 6 parts, Radix Scrophulariae: 8 parts, Radix Salviae Miltiorrhizae: 8 parts, Cinnabaris: 8 parts, Radix Platycodonis: 10 parts.The Chinese medicine preparation of making of the present invention is by said components and proportioning, is ground into 400 order fine powders, and every 100g medicated powder adds the decocting of 300ml to make condensed cream, by the granulator corning, and dry getting final product, every about 0.1-0.15g.

Example 3:

Described Chinese medicine preparation mass ratio is divided into: Radix Rehmanniae: 12 parts, and Radix Asparagi: 6 parts, Radix Ophiopogonis; 6 parts, Radix Salviae Miltiorrhizae: 5 parts, Semen Ziziphi Spinosae, 5 parts, Semen Platycladi: 6 parts, Radix Ginseng: 6 parts, 6 parts of Fructus Schisandrae Chinensis, Poria: 6 parts, Radix Polygalae: 6 parts, Radix Scrophulariae: 8 parts, Radix Salviae Miltiorrhizae: 8 parts, Cinnabaris: 8 parts, Radix Platycodonis: 12 parts.The Chinese medicine preparation of making of the present invention is by said components and proportioning, is ground into 400 order fine powders, and every 100g medicated powder adds the decocting of 300ml to make condensed cream, by the granulator corning, and dry getting final product, every about 0.1-0.15g.

Chinese traditional treatment dilated myocarditis of the present invention is dialectical method of thinking distinctive according to tcm diagnosis and treatment, is different from Western medicine such, and cardiopathia is controlled " heart ", but from the heart, liver, spleen, lung, the treatment of starting with of kidney integral body reaches the effect for the treatment of both the principal and secondary aspects of a disease.In recent years national departments concerned organizes the expert that treatment by Chinese herbs heart disease is investigated, and thinks that treatment by Chinese herbs heart disease not only has the adaptation national conditions, the advantage that side effect is low, and also curative effect is also definite reliable.This point has caused the concern of the relevant research worker of developed country.

Claims

1. treat the Chinese medicine preparation of dilated cardiomyopathy inflammation, it is characterized in that: crude drug weight ratio part of said preparation is: Radix Rehmanniae: 10-15 part, Radix Asparagi; 5-12 part, Radix Ophiopogonis; 6-12 part, Radix Salviae Miltiorrhizae: 5-10 part, Semen Ziziphi Spinosae; 5-12 part,, Semen Platycladi 5-12 part,, Radix Ginseng: 5-10 part,, Fructus Schisandrae Chinensis 54-12 part, Poria: 8-12 part, Radix Polygalae: 5-12 part, Radix Scrophulariae: 5-12 part, Radix Salviae Miltiorrhizae: 5-12 part, Cinnabaris: 5-12 part, Radix Platycodonis: 5-12 part.

2. the Chinese medicine preparation for the treatment of dilated cardiomyopathy inflammation as claimed in claim 1 is characterized in that: the best prescription pbw of the crude drug of said preparation is: Radix Rehmanniae: 10 parts, and Radix Asparagi: 6 parts, Radix Ophiopogonis; 6 parts, Radix Salviae Miltiorrhizae: 6 parts, Semen Ziziphi Spinosae; 6 parts,, Semen Platycladi: 8 parts, Radix Ginseng: 6 parts, 6 parts of Fructus Schisandrae Chinensis, Poria: 6 parts, Radix Polygalae: 6 parts, Radix Scrophulariae: 8 parts, Radix Salviae Miltiorrhizae: 8 parts, Cinnabaris: 8 parts, Radix Platycodonis: 10 parts.

3. preparation method for the treatment of the Chinese medicine preparation of dilated cardiomyopathy inflammation; it is characterized in that: the method is that crude drug is carried out proportioning by said components; be ground into 300 order fine powders; every 100g medicated powder adds the decocting of 300ml to make condensed cream; granulated by granulator; dry getting final product, every about 0.1-0.15g.