CN103155927A - Sterilization composition containing benzothiostrobin and epoxiconazole - Google Patents
Sterilization composition containing benzothiostrobin and epoxiconazole Download PDFInfo
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- CN103155927A CN103155927A CN2013101052846A CN201310105284A CN103155927A CN 103155927 A CN103155927 A CN 103155927A CN 2013101052846 A CN2013101052846 A CN 2013101052846A CN 201310105284 A CN201310105284 A CN 201310105284A CN 103155927 A CN103155927 A CN 103155927A
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Abstract
The invention relates to a sterilization composition containing benzothiostrobin and epoxiconazole. The sterilization composition containing benzothiostrobin and epoxiconazole comprises active ingredients and auxiliary components of pesticide preparations, wherein the active ingredients are composed of benzothiostrobin and epoxiconazole in weigh ratio of 1: (0.1-16). The sterilization composition containing benzothiostrobin and epoxiconazole has a very remarkable synergistic effect by compounding benzothiostrobin and epoxiconazole according to a special proportion; and lots of experiments prove that after benzothiostrobin and epoxiconazole are compounded, the toxicity to mammals is not increased. In addition, the applicant further finds that the compounding effect of benzothiostrobin and epoxiconazole can be further promoted by adopting a specific dispersion wetting agent with the help of the sterilization composition, so that benzothiostrobin and epoxiconazole give play to the synergistic effect to the maximum extent.
Description
Technical field
The invention belongs to pesticide field, particularly a kind of bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole.
Background technology
The methoxy acrylate germicide series class that to be the eighties of last century the eighties developed by Syngenta Co.,Ltd is efficient, wide spectrum, eco-friendly bactericide.Benzene thiophene bacterium ester due to have sterilization widely, the weeding isoreactivity is subject to the great parent of people and narrows and pay close attention to.
Benzene thiophene bacterium ester has the broad-spectrum sterilization activity, not only cucumber downy mildew and powdery mildew is had good preventive effect, all has good inhibition active for scab, anthracnose, gray mold, corn southern leaf blight, false smut, banana blight, banana sigatoka leaf spot disease.But the long-term solvent that uses separately develops immunity to drugs disease.Composite between the active ingredient of the different mechanisms of action is to delay the common practices that disease develops immunity to drugs, according to the effect in actual production.Composite effective formula can obviously improve preventive effect, greatly reduces the consumption of agricultural chemicals, enlarges fungicidal spectrum, improves sterilization, alleviates the pollution to environment, reduces agricultural cost.
Epoxiconazole is a kind of interior absorption triazole bactericidal agent, and its active component epoxiconazole suppresses the synthetic of germ ergosterol, hinders the formation of germ cell wall, is C-14 demethylation enzyme inhibitor in sterol biosynthesis, has protection and therapeutic action concurrently.Ten multiple diseases such as a series of cereal crops such as damping off, powdery mildew, eyeprint disease are had good preventive and therapeutic effect, and can prevent and treat the diseases such as sugar beet, peanut, rape, lawn, coffee, paddy rice and fruit tree.Not only have good protection, treat and root out activity, and have interior suction and better residual activity.
So far, only finding that CN102302012A is disclosed carries out the composite report of obtaining remarkable synergistic function with benzene thiophene bacterium ester and nitrile bacterium azoles.And it is relatively many to carry out composite report about epoxiconazole and other bactericide.But do not find benzene thiophene bacterium ester and epoxiconazole are carried out composite correlative study or report.
In addition, existing agriculture chemical compounding patent is mainly all only considered the composite synergistic effect that brings, yet, although synergistic effect is more obvious better, be not but to use unique factor of considering as agricultural chemicals, what also need especially to consider is, toxicity and the problem of environmental pollution of the composition after composite.For example, although some active component uses problem little separately, after composite use, bad chemical reaction may occur and cause problem of environmental pollution in the intermediate product that produces in their degradation process.
Therefore, provide and truly have synergistic effect and composite toxicity not to have the bactericidal composition that increase, composition are simple, problem of environmental pollution is less significant.
Summary of the invention
Technical problem to be solved by this invention is to provide the bactericidal composition that a kind of control efficiency is good, resistance is low, safety is good.
For solving above technical problem, following technical scheme of the present invention:
A kind of bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole, it is comprised of active component and pesticidal preparations auxiliary element, and particularly, described active component is made of 1:0.1～16 by weight ratio benzene thiophene bacterium ester and epoxiconazole.
Preferably, described active component is made of 1:0.2～12 by weight ratio benzene thiophene bacterium ester and epoxiconazole.More preferably, active component is made of 1:1～8 by weight ratio benzene thiophene bacterium ester and epoxiconazole, further preferably, active component by benzene thiophene bacterium ester and epoxiconazole by weight ratio 1:3 form.When composite according to this ratio, not only reached the most significant synergistic effect when benzene thiophene bacterium ester and epoxiconazole, and maximum low, the safe for human and animal and environment advantage of toxicity that has kept the epoxiconazole single dose.
According to the present invention, the preferred formulation of bactericidal composition is water dispersible granules and suspending agent.
Preferably, the pesticidal preparations auxiliary element in composition includes dispersion moisture agent.
According to a concrete aspect of the present invention, described bactericidal composition is water dispersible granules, and in weight content, it is composed as follows: active component 5%～90%; Dispersion moisture agent 2%～15%; Disintegrant 2%～8%, binding agent 2%～10% and filler surplus.
When bactericidal composition was water dispersible granules, the weight content that active component preferably accounts for described bactericidal composition was 15%～80%.
In water dispersible granules, dispersion moisture agent is preferably by alkylnaphthalene sulfonate and lignin or derivatives thereof sulfonate and forms by weight 1:0.5～15.
Disintegrant can be for being selected from one or more the combination in alkyl phenol polyether, crospolyvinylpyrrolidone, crosslinked carboxymethyl fecula sodium, low-substituted hydroxypropyl cellulose, Ac-Di-Sol and carboxymethyl cellulose.
In water dispersible granules, binding agent can be for being selected from starch, dextrin, gum Arabic, soybean protein, sodium silicate, gypsum, polyvinyl alcohol, polyvinyl acetate, ethene-vinyl acetate copolymer resins etc.Filler can be such as calcite, clay, kaolin, talcum, quicklime, diatomite, soybean, atlapulgite, mineral salt, diatomite, bentonite, white carbon, silica gel etc.
A preparation process of water dispersible granules is as follows: first with epoxiconazole, benzene thiophene bacterium ester, dispersion moisture agent, disintegrant, the filler premixed of formula ratio, mixed material mixes again, then pulverize through airslide disintegrating mill, material after pulverizing is changed over to add water and the kneading of formula ratio binding agent in kneader, extruder grain is drying to obtain.
According to another concrete aspect of the present invention, bactericidal composition is suspending agent, and in weight content, it is composed as follows: active component 5%～90%; Dispersion moisture agent 2%～15%, thickener 0.5%～5%, antifreezing agent 1%～10%, preservative 0.1%～5% and deionized water surplus.
In suspending agent, dispersion moisture agent preferably is comprised of by weight 1:0.5～15 lignin or derivatives thereof sulfonate and dodecyl sulphate calcium.
In suspending agent, thickener can be for being selected from one or several in gum Arabic, xanthans, methylcellulose, calcium carboxymethylcellulose, CMC, sodium starch phosphate, Sodium Polyacrylate and sodium carboxymethylcellulose.
In suspending agent, antifreezing agent can be for being selected from one or several in isopropyl alcohol, ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), butyl glycol ether, propandiol butyl ether, 2-Butoxyethyl acetate, calcium chloride, sodium acetate and magnesium chloride.
In suspending agent, preservative can be for being selected from one or several in formaldehyde, potassium sorbate, dehydro sodium acetate, calcium propionate, sodium Diacetate, sodium lactate, propylparaben and Sodium Benzoate.
A preparation process of suspending agent is as follows: epoxiconazole, benzene thiophene bacterium ester, dispersion moisture agent, thickener, antifreezing agent and the deionized water of formula ratio are mixed, adopt high-speed shearing machine to carry out just pulverizing, then change in the serialization sand mill and grind, and get final product.
Composition of the present invention can improve preventive effect to Common Diseases on fruit tree, vegetables and cereal crop and be of value to and delay the drug-fast generation of germ.
Owing to adopting above technical scheme, the present invention compared with prior art has following advantage:
The present invention carries out benzene thiophene bacterium ester and epoxiconazole composite in the certain proportion scope, obtained the synergistic function of highly significant, preventive effect is higher than monomer, dosage is little and enlarged fungicidal spectrum, and the diseases such as crop powdery mildew, leaf spot, anthracnose, downy mildew, false smut, scab, spot defoliation, damping off are had special efficacy.In addition, through experimental results demonstrate, composite do not have increase afterwards to mammalian toxicity, to crop and Environmental security, is conducive to the sustainable development of environment.Water dispersible granules provided by the invention and suspending agent do not contain organic solvent, are difficult for producing poisoning, store and convenient transportation, have particularly further improved the drug effect of composition due to the use of specific dispersion moisture agent.
Embodiment
Below in conjunction with specific embodiment, the present invention is described in further details.Following percentage composition is weight content.
Embodiment 1 22% benzene thiophene bacterium ester epoxiconazole suspension concentrate
Composition of raw materials is referring to table 1, and wherein, thickener is gum Arabic, and antifreezing agent is propane diols, and preservative is formaldehyde.
The preparation method of suspending agent is as follows: by formula, each raw material is joined in sand cylinder, after stirring, use again the high shear machine pre-dispersed, then change the sand mill sand milling over to, add sand milling medium zirconium oxide bead, the beginning sand milling, make the average grain diameter of material below 3 μ m, stop sand milling after 5 hours, filter, remove zirconium oxide bead, and get final product.
The technical indicator of gained suspending agent is as follows: suspensibility 〉=90.0%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤4.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=86.2% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=86.6% after 30 days.
Embodiment 2 30% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans, and antifreezing agent is ethylene glycol, and preservative is the sorb sodium alkoxide.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=91.5%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=87% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=87% after 30 days.
Embodiment 3 40% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.2:2), and antifreezing agent is isopropyl alcohol, and preservative is the sorb sodium alkoxide.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=93.5%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=90% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=90% after 30 days.
Embodiment 4 50% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.15:2.25), and antifreezing agent is butyl glycol ether and sodium chloride (weight ratio 1:2), and preservative is Sodium Benzoate.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=93.5%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=91% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=91% after 30 days.
Embodiment 5 32% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.15:2.25), and antifreezing agent is 2-Butoxyethyl acetate, and preservative is dehydro sodium acetate.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=96%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=91% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=91% after 30 days.
Embodiment 6 65% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.2:2), and antifreezing agent is sodium acetate, and preservative is calcium propionate.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=93.5%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=91% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=91% after 30 days.
Embodiment 7 51% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.3:1.5), and antifreezing agent is urea, and preservative is potassium sorbate.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=93.5%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=91% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=91% after 30 days.
Embodiment 8 40% benzene thiophene bacterium ester epoxiconazole suspension concentrates
Composition of raw materials is referring to table 1, and wherein, thickener is xanthans and methylcellulose (weight ratio 0.2:2), and antifreezing agent is sodium acetate, and preservative is sodium Diacetate.
The suspending agent preparation method is with embodiment 1, and the technical indicator of gained suspending agent is as follows: suspensibility 〉=88%; PH value 6.0～8.0; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Pourability: topple over rear residue≤3.0%, residue after washing≤0.5%; 54 ± 2 ℃ of heat are store suspensibility 〉=84% after 30 days; 0 ± 2 ℃ of cold storage suspensibility 〉=84% after 30 days.
The composition of raw materials of table 1 embodiment 1～8 benzene thiophene bacterium ester epoxiconazole suspension concentrate
Embodiment 9 12% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is crosslinked carboxymethyl fecula sodium and alkyl phenol polyether (weight ratio 1:1.5), and binding agent is starch, and filler is kaolin.
The preparation method of water dispersible granules is as follows: by filling a prescription each raw material premixed except binding agent, through coarse crushing, after mixing again, airslide disintegrating mill are pulverized, join in cone-type mixer, the average grain diameter of mixed material is below 3 μ m, the aqueous solution of adding additives is mediated, and extruder grain is dried and get final product.
The technical indicator of gained water dispersible granules is as follows: suspensibility 〉=90%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=85% after 30 days.
Embodiment 10 18% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is crospolyvinylpyrrolidone, and binding agent is gum Arabic, and filler is diatomite.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=90%; Wetting time≤30s; Moisture≤2.5%; PH value 6.0～8.0; Dispersed 〉=89%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤25ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=88% after 30 days.
Embodiment 11 40% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is carboxymethyl cellulose, and binding agent is polyvinyl acetate, and filler is bentonite.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=92%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=88% after 30 days.
Embodiment 12 30% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is low-substituted hydroxypropyl cellulose, and binding agent is polyvinyl alcohol, and filler is bentonite.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=92%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=88% after 30 days.
Embodiment 13 45% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is crosslinked carboxymethyl fecula sodium, and binding agent is polyvinyl alcohol, and filler is precipitated calcium carbonate.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=92%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=88% after 30 days.
Embodiment 14 52% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is crosslinked carboxymethyl fecula sodium, and binding agent is polyvinyl alcohol, and filler is precipitated calcium carbonate.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=90%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Foaming characteristic (after 1min) of a specified duration≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=85% after 30 days.
Embodiment 15 42.5% benzene thiophene bacterium ester epoxiconazole water dispersants
Composition of raw materials is referring to table 2, wherein: disintegrant is crospolyvinylpyrrolidone, and binding agent is diatomite, and filler is precipitated calcium carbonate.
The preparation method of water dispersible granules such as embodiment 9, the technical indicator of gained water dispersible granules is as follows: suspensibility 〉=90%; Wetting time≤30s; Moisture≤2.5%; PH value 5.0～8.0; Dispersed 〉=90%; Screen analysis (by 75 μ m hole sizers) 〉=98%; Lasting foaming characteristic (after 1min)≤30ml; Particle size range (0.8mm～1.5mm) 〉=95%; 54 ± 2 ℃ of heat are store suspensibility 〉=85% after 30 days.
The composition of raw materials of table 2 embodiment 9～15 benzene thiophene bacterium ester epoxiconazole water dispersants
The Toxicity Determination of complex composition to soybean anthracnose
1, test method
Choose the consistent large bean seedlings (approximately 5 leaf phases) of growth, each processing selects 3 basins for the examination seedling.With test atomizer spray, the about 5ml of every basin.Inoculation in 24 hours after chemicals treatment, adopt the anthracnose spore suspension evenly to be seeded on plant, then Hot Pepper Seedling is put into hot-house culture, carry out state of an illness investigation according to the morbidity grade scale after 14 days, and calculating control efficiency, then calculate concentration EC50 in inhibition with method of least squares, then calculate co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.
CTC≤80 expression composition performances are antagonism; When 80＜CTC＜120, the expression said composition shows as addition; When CTC 〉=120, the expression said composition shows as synergistic effect.
Actual measurement toxicity index (ATI)=(standard medicament EC50/ reagent agent EC50) * 100
The percentage composition of B in the percentage composition of A+B medicament toxicity index * mixture in theoretical toxicity index (TTI)=A medicament toxicity index * mixture.
Co-toxicity coefficient (CTC)=[actual measurement toxicity index (ATI)/theoretical toxicity index (TTI)] * 100.
2, test result is partly listed in table 3.
Table 3
As can be seen from Table 3, benzene thiophene bacterium ester and epoxiconazole are composite has good control efficiency to soybean anthracnose, at benzene thiophene bacterium ester: the epoxiconazole weight ratio is 1:0.1～16, CTC is obviously greater than 170, benzene thiophene bacterium ester: the epoxiconazole weight ratio is 1:0.2～12 o'clock, CTC is obviously greater than 190, benzene thiophene bacterium ester: the epoxiconazole weight ratio is 1:1～8 o'clock, CTC is greater than 200, particularly benzene thiophene bacterium ester: when the epoxiconazole weight ratio was 1:3, CTC was up to 238, synergistic effect is remarkable, reality can improve preventive effect in using, and reduces dosage, reduces and uses agriculture originally.
Field control effectiveness test
(1) composition of embodiment 1～15 carried out the field corn downy mildew test of pesticide effectiveness.
This test arrangement contrasts medicament 20% benzene thiophene bacterium ester suspending agent (commercial), 7.5% epoxiconazole missible oil and 12.5% epoxiconazole suspension concentrate in suburb, Lianshui County, Jiangsu Province.The investigation corn downy mildew state of an illness before medication, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days is once executed 3 times altogether.Investigated respectively disease index and calculated preventive effect in 7 days, 14 days, 21 days after last dispenser.Result of calculation is referring to table 4.
Table 4
To sum up; bactericidal composition of the present invention; remain good composite stability between two kinds of active components in use, compare expanding prevention disease scope with single dose epoxiconazole or benzene thiophene bacterium ester control corps diseases; delay drug-fast generation; obviously improve drug effect, reduced dosage and the spraying times of every mu of use, alleviated peasant burden; promote peasant's increasing both production and income, ensured better agriculture safety in production and protected ecotope.Be applied to agricultural plant chemoproection field, the harm of the germs such as fruit tree, vegetables, wheat, paddy rice is had excellence, protection and therapeutic action efficiently.
(2) composition of embodiment 1～15 is carried out the field pear tree black spot test of pesticide effectiveness
This experimental establishment is researched and developed/is provided by Jiangsu Qizhou Green Chemical Co., Ltd for reagent in suburb, Lianshui County, Jiangsu Province, contrast medicament 7.5% epoxiconazole missible oil,
The investigation pear tree black spot state of an illness before medication, in the dispenser for the first time of state of an illness initial stage, dispenser in every 10 days is once executed 2 times altogether.After dispenser 7 days for the second time, 14 days, investigated respectively pear tree black spot disease index and calculated preventive effect in 30 days.Experimental result is as shown in table 5.
Table 5
(3) composition of embodiment 1～6 is prevented and treated the bitter rot or anthracnose of grape test of pesticide effectiveness
This experimental establishment is in the suburb, Suqian, and test medicine is researched and developed, provided by Jiangsu Qizhou Green Chemical Co., Ltd, the contrast medicament.
Investigation bitter rot or anthracnose of grape disease index before medicine, in the their early stage dispenser, every dispenser on the 7th once, dispenser is 2 times altogether, for the second time 7 days, 14 days, 30 days refined calculating preventive effects of investigation disease index after dispenser.Experimental result is as shown in table 6.
Table 6
As can be seen from Table 6, can effectively prevent and treat bitter rot or anthracnose of grape after benzene thiophene bacterium ester and epoxiconazole are composite, control efficiency all is better than the single dose preventive effect, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
(4) composition of embodiment 7～15 is prevented and treated the alternaria leaf spot of apple test of pesticide effectiveness
This experimental establishment is in the suburb, Suqian, and test medicine is researched and developed, provided by Jiangsu Qizhou Green Chemical Co., Ltd, the contrast medicament.
Investigation spot defoliation disease index before medicine, in the their early stage dispenser, every dispenser on the 7th once, dispenser is 2 times altogether, for the second time 7 days, 14 days, 30 days refined calculating preventive effects of investigation disease index after dispenser.Experimental result is as shown in table 7:
Table 7
As can be seen from Table 7, can effectively prevent and treat alternaria leaf spot of apple after benzene thiophene bacterium ester and epoxiconazole are composite, control efficiency all is better than the single dose preventive effect, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Toxicity test
Determine that in Toxicity Determination test and field control effectiveness test composition has anthracnose of crop, spot defoliation etc. on the basis of excellent preventive effect, has carried out the acute toxicity detection.Result is referring to table 8.
Table 8
As can be seen from Table 8, benzene thiophene bacterium ester and epoxiconazole are composite rear to the not obviously increase of honeybee, Japanese quail, trout and rat toxicity, in the scope of application, the target crop are had no adverse effects.Consider medicament to multiple mammiferous toxicity, bactericidal composition of the present invention is all superior than single dose, Risk Reduction.
Above-described embodiment only is explanation technical conceive of the present invention and characteristics; its purpose is to allow person skilled in the art scholar can understand content of the present invention and implement according to this; can not limit protection scope of the present invention with this; all equivalences that Spirit Essence is done according to the present invention change or modify, within all should being encompassed in protection scope of the present invention.
Claims (10)
1. bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole, it is comprised of active component and pesticidal preparations auxiliary element, it is characterized in that: described active component is made of 1:0.1 ~ 16 by weight ratio benzene thiophene bacterium ester and epoxiconazole.
2. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 1, it is characterized in that: described active component is made of 1:0.2 ~ 12 by weight ratio benzene thiophene bacterium ester and epoxiconazole.
3. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 2, it is characterized in that: described active component is made of 1:1 ~ 8 by weight ratio benzene thiophene bacterium ester and epoxiconazole.
4. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 3 is characterized in that: described active component by benzene thiophene bacterium ester and epoxiconazole by weight ratio 1:3 form.
5. the described bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole of any one claim according to claim 1 to 4, it is characterized in that: the formulation of described bactericidal composition is suspending agent or water dispersible granules.
6. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 5, it is characterized in that: described pesticidal preparations auxiliary element includes dispersion moisture agent.
7. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 6, it is characterized in that: described bactericidal composition is water dispersible granules, in weight content, it is composed as follows: active component 5% ~ 90%; Dispersion moisture agent 2% ~ 15%; Disintegrant 2% ~ 8%, binding agent 2% ~ 10% and filler surplus.
8. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 7 is characterized in that: described dispersion moisture agent is comprised of by weight 1:0.5～15 alkylnaphthalene sulfonate and lignin or derivatives thereof sulfonate; Described disintegrant is to be selected from one or several in crospolyvinylpyrrolidone, crosslinked carboxymethyl fecula sodium, low-substituted hydroxypropyl cellulose, Ac-Di-Sol, ammonium sulfate, magnesium chloride, aluminium chloride, urea, anhydrous sodium sulfate, polyethyl acrylate and calcium chloride; Described binding agent is to be selected from one or several in starch, dextrin, gum Arabic, soybean protein, sodium silicate, gypsum, polyvinyl alcohol, polyvinyl acetate and ethene-vinyl acetate copolymer resins; Described filler is to be selected from one or several in calcite, clay, kaolin, talcum, quicklime, diatomite, soybean, atlapulgite, mineral salt, diatomite, bentonite, white carbon and silica gel.
9. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 6, it is characterized in that: described bactericidal composition is suspending agent, in weight content, it is composed as follows: active component 5% ~ 90%; Dispersion moisture agent 2% ~ 15%, thickener 0.5% ~ 5%, antifreezing agent 1% ~ 10%, preservative 0.1% ~ 5% and deionized water surplus.
10. the bactericidal composition that contains benzene thiophene bacterium ester and epoxiconazole according to claim 9 is characterized in that: described dispersion moisture agent is comprised of by weight 1:0.5～15 lignin or derivatives thereof sulfonate and dodecyl sulphate calcium; Described thickener is to be selected from one or several in gum Arabic, xanthans, methylcellulose, calcium carboxymethylcellulose, propylene glycol alginate and Sodium Polyacrylate; Described antifreezing agent is to be selected from one or several in isopropyl alcohol, ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), butyl glycol ether, propandiol butyl ether, 2-Butoxyethyl acetate, calcium chloride, sodium acetate and magnesium chloride.
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| CN2013101052846A CN103155927A (en) | 2013-03-28 | 2013-03-28 | Sterilization composition containing benzothiostrobin and epoxiconazole |
| CN201410123281.XA CN103828817B (en) | 2013-03-28 | 2014-03-28 | Sterilizing composition containing benzothiostrobin and epoxiconazole |
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| CN2013101052846A CN103155927A (en) | 2013-03-28 | 2013-03-28 | Sterilization composition containing benzothiostrobin and epoxiconazole |
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| CN103828817A (en) * | 2013-03-28 | 2014-06-04 | 江苏七洲绿色化工股份有限公司 | Sterilizing composition containing benzothiostrobin and epoxiconazole |
| CN104472504A (en) * | 2014-11-18 | 2015-04-01 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Sterilization composition containing epoxiconazole and thiabendazole and application thereof |
| CN106614627A (en) * | 2016-12-07 | 2017-05-10 | 佛山市普尔玛农化有限公司 | Bactericidal composition containing benzothiostrobin and kasugamycin |
| CN106718387A (en) * | 2016-11-19 | 2017-05-31 | 蚌埠市涂山村富民石榴专业合作社 | A kind of prevention and controls of pomegranate scab |
| CN106900727A (en) * | 2017-03-06 | 2017-06-30 | 佛山市瑞生通科技有限公司 | Active agent combinations containing benzothiostrobin and S-Ethyl ethylthio sulfonate |
| CN107094774A (en) * | 2017-05-06 | 2017-08-29 | 佛山市瑞生通科技有限公司 | Synergistic composition containing benzothiostrobin |
| CN108064855A (en) * | 2016-11-11 | 2018-05-25 | 华中师范大学 | A kind of composition pesticide and its application containing benzothiostrobin and prothioconazoles |
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| CN106718387A (en) * | 2016-11-19 | 2017-05-31 | 蚌埠市涂山村富民石榴专业合作社 | A kind of prevention and controls of pomegranate scab |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN103828817A (en) | 2014-06-04 |
| CN103828817B (en) | 2015-04-15 |
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