Summary of the invention
The deficiency that exists in order to overcome above-mentioned prior art, inventor and team thereof last 5 years, through contrast test repeatedly and the checking of up to a hundred times, provide a kind of have promoting blood flow to regulate menstruation effect and the splendid red rose health preparation (capsule) of Margarita of cosmetic result.
Technical scheme of the present invention is: the red rose health preparation of a kind of Margarita is comprised of following raw material: soluble pearl powder, and Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract, its weight proportion is: soluble pearl powder: Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract=1-3:2-4.
Described soluble pearl powder is that the method for the patent of invention (201110300941.3) of declaring on October 9th, 2011 according to Hunan Jinzhu Biotechnology Co., Ltd. makes.
Described Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract are made by following manner:
The first step: get dried Flos Rosae Rugosae ,-20 ℃ of frozen dryings become powder 100-200 order; Get and be ground into the 100-200 order under Radix Salviae Miltiorrhizae room temperature, stand-by, wherein the amount ratio of dried Flos Rosae Rugosae and Radix Salviae Miltiorrhizae is 1:1;
Second step: get above-mentioned powdery dry Flos Rosae Rugosae and Radix Salviae Miltiorrhizae powder, press 1:1-2 or 1-2:1 and mix, 95% ethanol that adds 5-8 doubly to measure, 30-45 ℃ is extracted 2-4h, filters, and is divided into filtrate and filtering residue, stand-by;
The 3rd step: get above-mentioned filtering residue and add again 5-8 and doubly measure 50% ethanol extraction 2-3h, filter, be divided into filtrate and filtering residue, stand-by;
The 4th step: the filtering residue of getting in the 3rd step is packed in stainless steel cauldron, adding pH value by liquid-solid ratio 10:1-14:1 is 1.0-3.0 water, extraction pressure is 3-5MPa, extracting temperature is 40-60 ℃, extraction time 55-75min filters, and abandons out filtering residue, filtrate directly becomes powdered at 35-45 ℃ of drying under reduced pressure, and is stand-by;
The 5th step: get second step, the filtrate mixing in the 3rd step, 30-45 ℃ of drying under reduced pressure becomes powdered, and be stand-by;
The 6th step: the dry powder of getting in the 4th step, the 5th step fully mixes, and is Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract.
The said extracted method has following advantage: the one, and first with organic solvent, the rear water preparation of using, not only extract yield is higher than other method 5-10%, and extracts active ingredients is comprehensive; The 2nd, mixed extraction shortens the time shorter greatly, can save the time more than 20%; The 3rd, to the active component destruction few (when extracting tanshinone in salvia miltiorrhiza bunge II and salvianolic acid B, solvent strength affects highly significant to result, and thickening temperature also has certain influence) of extract; The 4th, its effect of preparation of getting with the preparation score dispersing and elevation of this extracting method extraction strengthens more than 18%; The 5th, this extracting method almost contains the whole part of two kinds of materials after measured; The 6th, increase soluble pearl powder on the basis of Flos Rosae Rugosae, Radix Salviae Miltiorrhizae, Margarita powder has played the effect of " catalysis ", and effect improves more than 25%.
The present invention has the following advantages: in effective ingredient of the present invention, the soluble pearl powder oral absorption is good, has increased the various elements of needed by human body, and not only beautifying whitening is effective, and the scalable human endocrine, improves women's menoxenia; Radix Salviae Miltiorrhizae also has the effect of promoting blood flow to regulate menstruation, promoting tissue regeneration by removing blood stasis, helps improve the female incretion environment; Oxidation-resistant active ingredient in Flos Rosae Rugosae can be removed more by force excessive free radicals in body, really plays the effects such as looks improving and the skin nourishing, dredge the meridian passage, vessel softening, for cardiovascular and cerebrovascular vessel, hypertension, heart disease and gynecological, significant curative effect is arranged.The phenomenons such as several active component in raw material of the present invention can improve that menoxenia, chloasma and wrinkle that the working woman high pressure brings are grown thickly really play prevention from the interior environment involutional in advance and improve the climacteric phenomenon.
The specific embodiment
Now in conjunction with specific embodiments, technology contents of the present invention is further described.
Embodiment one: the ratio in raw material and extract of first getting is that the 10:1 method is extracted and Flos Rosae Rugosae, the Radix Salviae Miltiorrhizae mixed extract 200g of dried powdery, add again soluble pearl powder 100g, proportionally mix homogeneously, make 600 capsules according to conventional method at last.
Embodiment two: the ratio in raw material and extract of first getting is that the 10:1 method is extracted and Flos Rosae Rugosae, the Radix Salviae Miltiorrhizae mixed extract 400g of dried powdery, add again soluble pearl powder 300g,, proportionally mix homogeneously, make 1000 capsules according to conventional method at last.
For above two preferred embodiments, its acquisition about Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract now provides following example to illustrate:
Example 1: the first step: get dried Flos Rosae Rugosae 1000g ,-20 ℃ of frozen dryings become powder 100-200 order; Get under Radix Salviae Miltiorrhizae 1000g room temperature and be ground into the 100-200 order, stand-by;
Second step: get above-mentioned powdery dry Flos Rosae Rugosae and Radix Salviae Miltiorrhizae powder, press 1:1-2 and mix, add 95% ethanol of 5 times of amounts, 45 ℃ are extracted 3h, filter, and are divided into filtrate and filtering residue, stand-by;
The 3rd step: get above-mentioned filtering residue and add again 5 times of amount 50% ethanol extraction 3h, filter, be divided into filtrate and filtering residue, stand-by;
The 4th step: the filtering residue of getting in the 3rd step is packed in stainless steel cauldron, and adding pH value by liquid-solid ratio 10:1 is 2.0 water, and extraction pressure is 4MPa, extracting temperature is 50 ℃, and extraction time 60min filters, abandon out filtering residue, filtrate directly becomes powdered at 35 ℃ of drying under reduced pressure, and is stand-by;
The 5th step: get second step, the filtrate mixing in the 3rd step, 35 ℃ of drying under reduced pressure powdering shapes, stand-by;
The 6th step: the dry powder of getting in the 4th step, the 5th step fully mixes, and is Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract, and its extracted amount is 10% left and right of material quantity.
Example 2: the first step: get dried Flos Rosae Rugosae 1000g ,-20 ℃ of frozen dryings become powder 100-200 order; Get under Radix Salviae Miltiorrhizae 1000g room temperature and be ground into the 100-200 order, stand-by;
Second step: get above-mentioned powdery dry Flos Rosae Rugosae and Radix Salviae Miltiorrhizae powder, press 1-2:1 and mix, add 95% ethanol of 8 times of amounts, 30 ℃ are extracted 4h, filter, and are divided into filtrate and filtering residue, stand-by;
The 3rd step: get above-mentioned filtering residue and add again 8 times of amount 50% ethanol extraction 2h, filter, be divided into filtrate and filtering residue, stand-by;
The 4th step: the filtering residue of getting in the 3rd step is packed in stainless steel cauldron, and adding pH value by liquid-solid ratio 14:1 is 3.0 water, and extraction pressure is 5MPa, extracting temperature is 60 ℃, and extraction time 75min filters, abandon out filtering residue, filtrate directly becomes powdered at 45 ℃ of drying under reduced pressure, and is stand-by;
The 5th step: get second step, the filtrate mixing in the 3rd step, 45 ℃ of drying under reduced pressure powdering shapes, stand-by;
The 6th step: the dry powder of getting in the 4th step, the 5th step fully mixes, and is Flos Rosae Rugosae, Radix Salviae Miltiorrhizae mixed extract; Its extracted amount is 10% left and right of material quantity.
Health preparation of the present invention is tried out through many people, every day 3 times, each 6.Trial period 3-6 month, what positive effect was arranged reached 95%, below lifted several typical result of use examples:
Example 1, Zhao XX, 46 years old, facial old and feeble, chloasma was grown thickly, and the hormone in vivo secretion level reduces, and the health-caring capsule that the trial edition invention is made is after 6 months, and chloasma obviously subtracts light, and the hormone in vivo secretion level is close to normally.
Example 2, Liao XX, 35 years old, wrinkle was grown thickly on the face, easily tired easily dry, the climacteric reaction is strong, the health-caring capsule that the trial edition invention is made is after 4 months, wrinkle has reduced, the climacteric reaction has obtained alleviation, mental status also be improved significantly.
Example 3, Liu XX, 28 years old, often menoxenia, skin is also intensely dark, and after the health-caring capsule that the trial edition invention is made, after 3 months, menstruation recovery is normal, whiteness of skin and gloss has been arranged.