CN103100063A - Traditional Chinese medicine for treating damp-heat type gallstone - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating gallstone, and in particular relates to a traditional Chinese medicine for treating damp-heat type gallstone, which is prepared from the following components in parts by weight: 9-12 parts of chingma abutilon seed, 25-30 parts of stringy stonecrop, 12-15 parts of grifola, 20-30 parts of longhairy antenoron herb, 6-9 parts of cape jasmine fruit, 15-20 parts of abrus cantoniensis hance, 6-9 parts of golden cypress, 3-6 parts of herba aristolochiae, 3-6 parts of rhizoma nardostachyos, 6-9 parts of fructus aurantii, 6-9 parts of pericarpium citri reticulatae viride, 15-20 parts of verbena, 6-10 parts of whiteflower cacalia seed, 9-12 parts of radix curcumae,0.5-3 parts of barbados aloe and 6-12 parts of areca-nut. In the formula, abrus cantoniensis hance, pericarpium citri reticulatae viride, radix curcumae and cape jasmine fruit can sooth liver-gallbladder, clear heat, cool blood and remove stagnation; chingma abutilon seed, grifola, longhairy antenoron herb and herba aristolochiae can clear dampness, promote diuresis, clear heat and remove toxicity; longhairy antenoron herb and radix curcumae have a function of digesting gallstone; fructus aurantii and areca-nut serve as aids to depress qi and regulate qi, excrete water and excrete dyspepsia; stringy stonecrop, golden cypress, verbena and whiteflower cacalia seed can discharge fire, promote diuresis, eliminate stasis and subdue swelling; and therefore, functions of clearing liver-gallbladder, digesting and discharging gallstone can be enhanced. Meanwhile, rhizoma nardostachyos can promote appetite and refresh spleen, and barbados aloe can clear liver heat, so that spleen is tonified, liver is relived, and unfavourable causes of the liver and the gallbladder are eliminated. The traditional Chinese medicine has the advantages of having an effective rate of 100%, taking effect quickly, treating both symptoms and root causes and being safe and reliable.

Description

A kind of Chinese medicine for the treatment of the damp-heat type cholelithiasis

Technical field

The present invention relates to a kind of medicine for the treatment of cholelithiasis, relate in particular to a kind of Chinese medicine for the treatment of the damp-heat type cholelithiasis.

Background technology

Cholecystitis, cholelithiasis disease are more common biliary tract; Be mainly in women and overweight people.The categories such as " hypochondriac pain ", " blocked-up chest " of the cholelithiasis disease genus traditional Chinese medical science, " yellow cellulitis ".Theory of Chinese medical science, cholelithiasis disease, sick position is at the gallbladder internal organs, and is relevant with internal organs such as liver, gallbladder, spleen, stomaches; Often food delicious food, malnutrition due to parasitic infestation, diseases caused by exogenous pathogenic factor etc. do not relaxed, had a liking for because of feelings will, suffocating of liver and gall and transporting and transforming function of the spleen and stomach affected.Or causing QI stagnation of the liver and galibladder, gallbladder is let out not smooth; Or causing dysfunction of the spleen in transportation, with the passing of time retention of damp-heat in the interior decocts into stone; Or cause stagnation of QI internal organs and close, hematogenous blockage, pus is stopped up in blood stasis dispelling.This shows, although be both cholelithiasis disease, its pathology is different; When treatment, should for different pathology, divide and rule.

The Chinese medicinal formulae that is used for the treatment of at present cholecystitis and cholelithiasis is not divided and rule, although the cholelithiasis of different pathological all there is certain curative effect, not remarkable to the curative effect of the cholelithiasis disease of particular pathologies.

Summary of the invention

In order to solve existing Chinese medicinal formulae to the inapparent problem of the curative effect of damp-heat type cholelithiasis, the invention provides a kind of Chinese medicine for the treatment of the damp-heat type cholelithiasis; To the therapeutic effect of the cholelithiasis disease of damp and hot stifling symptom significantly, instant effect.

Technical scheme of the present invention:

A kind of Chinese medicine for the treatment of the damp-heat type cholelithiasis is prepared from by the crude drug of following weight parts:

9～12 parts of Semen Abutili, 25～30 parts of Herba Sedis, Polyporus 12-15 part, Herba Lysimachiae 20-30 part, 6～9 parts of Fructus Gardeniaes, 15～20 parts of Herba Abris, 6～9 parts of Cortex Phellodendris, Herba Aristolochiae 3-6 part, 3～6 parts of Radix Et Rhizoma Nardostachyos, 6～9 parts of Fructus Aurantiis, 6～9 parts, Pericarpium Citri Reticulatae Viride; 15～20 parts of Herba Verbenae, 6～10 parts of Semen Caesalpiniae Minaciss, 9～12 parts of Radix Curcumaes, 0.5～3 part of Aloe, 6～12 parts of Semen Arecaes.

The Chinese medicine for the treatment of damp-heat type cholelithiasis of the present invention can adopt the conventional preparation method of Chinese medicine to make honeyed pill except decoction, tablet, powder etc.; Aloe does not enter decoction.

The Chinese medicine of above-mentioned treatment damp-heat type cholelithiasis, preferably adopt following method to be prepared from:

(1) Aloe powder is broken to 400 orders, gets Aloe powder;

(2) Semen Abutili, Herba Sedi, Herba Lysimachiae, Herba Abri, Herba Aristolochiae, Fructus Aurantii, Semen Caesalpiniae Minacis are decocted with water 1.5-2.5h, filter, filtrate is condensed into the thick paste shape, gets component A;

(3) Polyporus, Fructus Gardeniae, Cortex Phellodendri, Radix Et Rhizoma Nardostachyos, Pericarpium Citri Reticulatae Viride, Herba Verbenae, Radix Curcumae, Semen Arecae are decocted with water 1.5-2h; Filter, filtrate is condensed into the thick paste shape, gets B component;

(4) with Aloe powder, component A and B component, mixing, dry, compacting in flakes, sugar coating or film-coat get final product.

The consumption of Chinese medicine of the present invention is: take crude drug as benchmark, 80-150g, divided and took for 2-4 time every day; 30 days is a course for the treatment of; Anemia of pregnant woman, menstrual period forbid.

The pharmacology analysis of each crude drug that the present invention is used:

Herba Sedi: cool in nature; Sweet in the mouth, light; Return liver, gallbladder, small intestine meridian; Heat clearing away, detumescence, detoxifcation;

Semen Abutili: property is flat; Bitter in the mouth; Return large intestine, small intestinal, urinary bladder channel; Clearing away heat-damp and promoting diuresis, detoxifcation;

Polyporus: property is flat; Sweet in the mouth is light; Return kidney, urinary bladder channel; Promoting diuresis to eliminate damp pathogen;

Herba Lysimachiae: cold nature; Sweet in the mouth, salty; Return liver, gallbladder, kidney, urinary bladder channel; Eliminating damp-heat, treating stranguria, detumescence;

Cortex Phellodendri: cold in nature; Bitter in the mouth; Return kidney, urinary bladder channel; Heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment;

Fructus Gardeniae: cold in nature; Bitter in the mouth; GUIXIN, lung, tri-jiao channel; The pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body;

Herba Abri: cool in nature; Sweet in the mouth, little hardship; Return liver, stomach warp; Heat-clearing and toxic substances removing, Shugan Zhitong;

Herba Aristolochiae: warm in nature, gas delicate fragrance, lightly seasoned little hardship; Return the liver,spleen,kidney warp: promoting flow of QI and blood, inducing diuresis to remove edema, detoxifcation.With

Radix Et Rhizoma Nardostachyos: warm in nature; Acrid in the mouth, sweet; Return spleen, stomach warp; Promoting the circulation of QI to relieve pain, relieving stagnation and activating the spleen;

Fructus Aurantii: warm in nature; Bitter in the mouth, suffering, acid; Return spleen, stomach warp; Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row;

Pericarpium Citri Reticulatae Viride: warm in nature; Acrid in the mouth, hardship; Return liver, gallbladder, stomach warp; Soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant;

Herba Verbenae: cool in nature; Bitter in the mouth; Return liver, spleen channel; Promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, detoxifcation, inducing diuresis to remove edema;

Semen Caesalpiniae Minacis: cold in nature; Bitter in the mouth; GUIXIN, spleen, kidney channel; Dissipating blood stasis, pain relieving, heat clearing away, damp eliminating;

Radix Curcumae: cold in nature; Acrid in the mouth, hardship; Return liver, gallbladder, heart channel; Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice;

Aloe: cold in nature; Bitter in the mouth; Return liver, large intestine channel; Removing heat from the liver, relieving constipation;

Semen Arecae: warm in nature; Bitter in the mouth, suffering; Return stomach, large intestine channel; Expelling intestinal worms and removing food stagnancy, sending down the abnormal ascending QI, row water.

The Chinese medicine meridian theory is thought, " gallbladder person, the mansion of middle essence ", its function had both relied on the catharsis of liver, stored bile, can promote transporting and transforming function of the spleen and stomach again, with transfer logical reduce to suitable; Dysfunction of the spleen in transportation, damp-heat accumulation are in liver and gall, and the liver network is become estranged, and with the passing of time not catharsis of gallbladder decocts into stone.The rule for the treatment of is with depressed liver-energy dispersing and function of gallbladder promoting, removing dampness calculus.In the side: Herba Abri, Pericarpium Citri Reticulatae Viride, Radix Curcumae and Fructus Gardeniae depressed liver-energy dispersing and function of gallbladder promoting also possess the stagnant effect of clearing away heat and cooling bloodization simultaneously; Semen Abutili, Polyporus, Herba Lysimachiae, Herba Aristolochiae promoting diuresis to eliminate damp pathogen, heat-clearing and toxic substances removing; Wherein, Herba Lysimachiae, Radix Curcumae also possess the effect of fossil; Same use, eliminating dampness by diuresis heat clearing away are with clearing liver-gallbladder, and then the fossil calculus.Be aided with, Fructus Aurantii and Semen Arecae sending down the abnormal ascending QI are regulated the flow of vital energy, row water is capable stagnant, Herba Sedi, Cortex Phellodendri, Herba Verbenae, Semen Caesalpiniae Minacis pathogenic fire purging diuretic, dissipating blood stasis for subsidence of swelling; To strengthen the effect of clearing liver-gallbladder fossil calculus.And the Radix Et Rhizoma Nardostachyos appetizing is amusing, the Aloe removing heat from the liver, thereby invigorating the spleen and relieving depression of liver-QI is eliminated the unfavorable root of liver and gall.

Beneficial effect of the present invention:

The Chinese medicine for the treatment of damp-heat type cholelithiasis of the present invention is used for the treatment of damp and hot fumigation type cholelithiasis, and clinical application effect is remarkable, and effective percentage reaches 100%; Both can rapid recovery ailing, can eradicate the cause of disease again, and can play the effect of spleen invigorating hepatoprotective, thereby effectively prevent disease relapse.Therefore, possess that with strong points, instant effect, specimen are held concurrently, safe and reliable advantage.

The test of pesticide effectiveness

For showing that the present invention is to the treatment therapeutic effect of fumigation type cholelithiasis, the present invention chooses 400 routine fumigation type gallstone patients through system's clinical observation, 400 routine patients are equally divided into four groups, four groups of patients are learning processing by statistics aspect sex, age, the state of an illness and the course of disease, no significant difference has comparability; Wherein three groups is test group, and one group is matched group.Enter the group standard: 1) age 〉=23 year old; 2) diameter of calculus is less than 5cm; 3) I or family members' informed consent.

The treatment measure

Test group 1: the honeyed pill of taking embodiments of the invention 1 preparation; Take crude drug as benchmark, medication every day 150g takes at twice, sooner or later respectively once;

Test group 2: the powder of taking embodiments of the invention 2 preparations; Take crude drug as benchmark, medication every day 90g divides and takes for 3 times;

Test group 3: the tablet of taking embodiments of the invention 3 preparations; Take crude drug as benchmark, medication every day 150g divides 2 to take;

Matched group: the medicine of taking the embodiment 1 in patent CN1233406C.

Criterion of therapeutical effect:

Invalid: disease and sign are without obvious improvement, and the every related index of laboratory examination is without being clearly better, and B-type ultrasonography and cholangiography check that its finding and treatment are front close, and calculus is the improver not;

Effectively: disease and sign alleviate, the imaging examination calculus reduce below 1/2 or calculus diminish below 1/2;

Produce effects: disease and sign obviously alleviate, and the obvious minimizing of imaging examination calculus reaches more than 1/2 or calculus diminishes more than 1/2;

Recovery from illness: disease and sign disappear fully, and the every related index of laboratory examination recovers normal, and B-type ultrasonography and cholangiography inspection confirm to exist without calculus.

Through the treatment of 6 months, respectively the therapeutic effect of test group and matched group to be added up, result is as shown in table 1;

Table 1

。The effective percentage of test group patient after taking medicine of the present invention 7 days is more than 15%, and the effective percentage of taking after 30 days is 99%, and therefore medicine of the present invention exists instant effect, advantage that effective percentage is high.Test group patient is after taking medicine of the present invention 180 days, and cure rate is 96%; Therefore medicine of the present invention exists that cure rate is high, repeatedly advantage not.

Model case

Lee, the man, 56 years old, persistence upper right abdominal distention and pain, pain is drawn the shoulder back of the body, the outbreak of heating fear of cold is uncomfortable in chest indigestion and loss of appetite, the nausea vomiting, bitter taste swallow in, yellowish fur, stringy and tense pulse; Through B-type ultrasonography and cholangiography inspection, suffer from gallbladder and be full of the type calculus, calculus diameter 4.7cm has 9 years medical histories, long-term multi-treatment, DeGrain.Tcm diagnosis is damp and hot stifling disease.Take the prepared medicine of embodiment 3, take at twice, ante cibum respectively once sooner or later.After medication 7 days, sx↓; After medication 1 month, disease and sign obviously alleviate, and imaging examination access node stone diameter is 2.9cm; After medication 3 months, disease disappears fully, and the every related index of laboratory examination recovers normal, and B-type ultrasonography and cholangiography inspection confirm to exist without calculus.Continue medication 15 days, to consolidate the state of an illness.Follow up a case by regular visits in 3 years, the state of an illness is without repeatedly.

The specific embodiment

Embodiment 1

Get the 0.5g Aloe powder and be broken to 400 orders;

Get Semen Abutili 9g, Herba Sedi 30g, Polyporus 12g, Herba Lysimachiae 30g, Fructus Gardeniae 6g, Herba Abri 20, Cortex Phellodendri 6g, Herba Aristolochiae 6g, Radix Et Rhizoma Nardostachyos 3g, Fructus Aurantii 9g, Pericarpium Citri Reticulatae Viride 6g; Herba Verbenae 12g, Semen Caesalpiniae Minacis 6g, Radix Curcumae 12g, Semen Arecae 12g; Add the 800ml decocting and boil 2h, filtration, concentrated filtrate add the Aloe powder modulation evenly to paste, make honeyed pill.

Embodiment 2

Semen Abutili 12g, Herba Sedi 30g, Polyporus 15g, Herba Lysimachiae 30g, Fructus Gardeniae 9g, Herba Abri 20, Cortex Phellodendri 9g, Herba Aristolochiae 6g, Radix Et Rhizoma Nardostachyos 6g, Fructus Aurantii 9g, Pericarpium Citri Reticulatae Viride 9g; Herba Verbenae 20g, Semen Caesalpiniae Minacis 6g, Radix Curcumae 9g, Aloe 3g, Semen Arecae 12g; Be crushed to 400 orders, fill gets final product.

Embodiment 3

Get the 3g Aloe powder and be broken to 400 orders, get Aloe powder;

Get Semen Abutili 12g, Herba Sedi 25g, Herba Lysimachiae 20g, Herba Abri 15g, Herba Aristolochiae 3g, Fructus Aurantii 6g, Semen Caesalpiniae Minacis 10g adds the 500ml decocting and boils 1.5h, filters, filtrate is condensed into the thick paste shape, gets component A;

Polyporus 15g, Fructus Gardeniae 9g, Cortex Phellodendri 9g, Radix Et Rhizoma Nardostachyos 6g, Pericarpium Citri Reticulatae Viride 9g, Herba Verbenae 15g, Radix Curcumae 9g, Semen Arecae 6g are added the 500ml decocting boil 1.5h; Filter, filtrate is condensed into the thick paste shape, gets B component;

With Aloe powder, component A and B component, mixing, dry, compacting in flakes, film coating gets final product.

Claims (2)

1. a Chinese medicine for the treatment of the damp-heat type cholelithiasis, is characterized in that, is prepared from by the crude drug of following weight parts:

9～12 parts of Semen Abutili, 25～30 parts of Herba Sedis, Polyporus 12-15 part, Herba Lysimachiae 20-30 part, 6～9 parts of Fructus Gardeniaes, 15～20 parts of Herba Abris, 6～9 parts of Cortex Phellodendris, Herba Aristolochiae 3-6 part, 3～6 parts of Radix Et Rhizoma Nardostachyos, 6～9 parts of Fructus Aurantiis, 6～9 parts, Pericarpium Citri Reticulatae Viride; 15～20 parts of Herba Verbenae, 6～10 parts of Semen Caesalpiniae Minaciss, 9～12 parts of Radix Curcumaes, 0.5～3 part of Aloe, 6～12 parts of Semen Arecaes.

2. the Chinese medicine for the treatment of damp-heat type cholelithiasis according to claim 1, is characterized in that, adopts following method to be prepared from:

(1) Aloe powder is broken to 400 orders, gets Aloe powder;

(2) Semen Abutili, Herba Sedi, Herba Lysimachiae, Herba Abri, Herba Aristolochiae, Fructus Aurantii, Semen Caesalpiniae Minacis are decocted with water 1.5-2.5h, filter, filtrate is condensed into the thick paste shape, gets component A;

(3) Polyporus, Fructus Gardeniae, Cortex Phellodendri, Radix Et Rhizoma Nardostachyos, Pericarpium Citri Reticulatae Viride, Herba Verbenae, Radix Curcumae, Semen Arecae are decocted with water 1.5-2h; Filter, filtrate is condensed into the thick paste shape, gets B component;

(4) with Aloe powder, component A and B component, mixing, dry, compacting in flakes, sugar coating or film-coat get final product.