CN1245709A - Chinese medicine for curing lithiasis - Google Patents

Abstract

The present invention discloses a Chinese medicine preparation for curing lithiasis. Said invented medicine preparation is made up by using 24 Chinese medicinal materials of gizzard lining, moneywort, lygodium spore, bushy knotweed root, gentian root, sweet wormwood, capillaris, scutellaria root, phellodendron bark, gardenia fruit, curcuma tuber, bitter orange, knotgrass, moutan root bark and red peony root, etc.. Said invention can be made into various dosage forms of powder, soluble granules, capsule, oral liquor, pill, tablet and injection, and is suitable for curing hepatolith, cholelithiasis, kidney stone, ureterolith and vesical calculus, and its effective rate is above 90%.

Description

Treat calculous medicine

The present invention relates to the calculous pharmaceutical preparation of treatment with the preparation of Chinese medicine natural drug.

The calculus that betides positions such as liver, gallbladder, kidney, ureter, bladder is commonly encountered diseases, a frequently-occurring disease clinically.Modern medicine mainly contains two kinds to calculous effective treatment means: surgical removal and ultrasound wave rubble.These two kinds of Therapeutic Method are reliable for effect, but certain indication restriction is all arranged, and are more suitable to calculus single-shot, that volume is bigger, and the calculus of the many places of occurring together just is difficult to carry out.Particularly general in the multiple liver calculus of common hepatic duct, all is indication anything but concerning surgical removal and ultrasound wave lithotripsy method.These two kinds of Therapeutic Method also cause certain damage to human body in implementation process, therefore except that the basic body constitution to the patient has the requirement of selection, also have the worry that multiple complications, sequela take place.

About calculous treatment, except that above-mentioned operation and hyperacoustic method, patent documentation and non-patent literature were also reported some " fossils " " the drive stone " drug treatment of " calculus ".These Chinese and western drugses also can not make the people satisfied aspect cure rate, effective percentage very much.The bigger side effect of also existence that has, perhaps drug dose is very big, use is inconvenient.Therefore still do not have so far a kind ofly generally to be accepted, generally acknowledge treatment calculosis medicine reliable for effect by medical circle.

I was devoted to treat calculous drug research since nineteen eighty-three, excavate the calculous side's medicine of treatment from Chinese traditional medicine, obtained important breakthrough to 1994, through checking, the improvement, perfect in several years, had finished the invention again.

The object of the present invention is to provide a kind of pharmaceutical preparation with the preparation of Chinese medicine natural drug, its making and use are all more convenient, can treat calculosis effectively, particularly hepatolithiasis are had reliable therapeutic effect.

The present invention seeks to choose by the following method Chinese medicine, manufacture dosage forms and realize.

One. medicine is formed: comprise Endothelium Corneum Gigeriae Galli Herba Lysimachiae Spora Lygodii Rhizoma Polygoni Cuspidati Radix Gentianae Herba Artemisiae Annuae Herba Artemisiae Scopariae Radix Scutellariae phellodendron and gardenia Radix Curcumae Fructus Aurantii Herba Polygoni Avicularis Cortex Moutan Radix Paeoniae Rubra Semen Plantaginis Radix Aucklandiae (Radix Vladimiriae) Fructus Toosendan Poria Rhizoma Alismatis Polyporus Fructus Chaenomelis Radix Bupleuri Scorzonerifolii Radix Et Rhizoma Rhei

In above 24 kinds of drug components, the Endothelium Corneum Gigeriae Galli ingredient can promote the wriggling of liver, bile duct and intestinal and reach the purpose of calculus, Sal Nitri, be we " monarch ".Herba Lysimachiae, Spora Lygodii have the urine of making to become the effect of acidity, diuresis, function of gallbladder promoting, are treatment liver, gallbladder, kidney, cystolithic principal agent, are in " minister " position in this prescription.The property of medicine of medicines such as Rhizoma Polygoni Cuspidati, Radix Gentianae, Herba Artemisiae Annuae, Herba Artemisiae Scopariae is gone into Liver Channel, gallbladder meridian, urinary bladder channel, is " assistant " medicine of we.All the other each medicines are " making " medicine.

Two. the usage ratio of each bulk drug (dry product percentage by weight) the membrane of a chicken's gizzard 10-15% desmodium 7-10% Lygodium japonicum 7-10% giant knotweed 5-8% felwort 5-8% sweet wormwood 4-7% Artemisia capillaris 4-7% root of large-flowered skullcap 3-6% golden cypress 3-6% cape jasmine 3-6% root tuber of aromatic turmeric 2-4% Fructus Aurantii 2-4% Armstrong 2-4% root bark of tree peony 2-4% radix paeoniae rubrathe 2-4% plantain seed 2-4% costus root 2-4% Fructus meliae toosendan 2-4% PORIA ALBA 1-3% rhizoma alismatis 1-3% umbellate pore furgus 1-3% pawpaw 1-3% RADIX BUPLEURI SCORZONERAEFOLII 1-3% rheum officinale 1-3%

Three. the preliminary working of medicine and the process of preparing Chinese medicine

1. medicines such as Herba Lysimachiae, Rhizoma Polygoni Cuspidati, Radix Gentianae, Herba Artemisiae Annuae, Radix Scutellariae, Radix Curcumae, Herba Polygoni Avicularis, Cortex Moutan, Radix Paeoniae Rubra, Radix Aucklandiae (Radix Vladimiriae), Polyporus, Fructus Chaenomelis are removed impurity, clean, and cutting or sheet dry.

2. Endothelium Corneum Gigeriae Galli, Fructus Gardeniae parch respectively.

3. Cortex Phellodendri, Fructus Toosendan, Semen Plantaginis, Rhizoma Alismatis do the salt stir-fry respectively.

4. Fructus Aurantii makes parched with bran.

5. Radix Bupleuri Scorzonerifolii is made vinegar system.

6. rhubarb tablets is made processed with wine.

7. other each medicines are removed impurity, sieve dedust bits get final product, and do not need special processing.

Four. preparation formulation

This prescription drug can be made multiple dosage form by usual way, as powder, electuary, capsule, oral liquid, pill, tablet, injection etc.Powder preferably.

The invention will be further described by the following examples.

Embodiment 1 makes powder

Take by weighing following 24 kinds of medicine dry products: the membrane of a chicken's gizzard 1500g desmodium 1000g Lygodium japonicum 1000g giant knotweed 800g felwort 800g sweet wormwood 600g Artemisia capillaris 600g root of large-flowered skullcap 500g golden cypress 500g cape jasmine 500g root tuber of aromatic turmeric 400g amasss shell 400g Armstrong 400g root bark of tree peony 400g radix paeoniae rubrathe 400g plantain seed 400g costus root 400g Fructus meliae toosendan 400g Poria cocos 200g rhizoma alismatis 200g umbellate pore furgus 200g pawpaw 200g RADIX BUPLEURI SCORZONERAEFOLII 200g rheum officinale 200g

Above medicine total amount is 12200 grams.

Preparation method:

1. medicines such as Spora Lygodii, Herba Artemisiae Scopariae, Poria are removed impurity, sieve dedust bits.

2. medicines such as Herba Lysimachiae, Rhizoma Polygoni Cuspidati, Radix Gentianae, Herba Artemisiae Annuae, Radix Curcumae, Herba Polygoni Avicularis, Cortex Moutan, Radix Paeoniae Rubra, Radix Aucklandiae (Radix Vladimiriae), Polyporus, Fructus Chaenomelis are removed impurity, clean, and cutting or sheet dry.

3. Radix Scutellariae: remove impurity, put in the boiling water stewing about 10 minutes, take out when hands is pinched softness, shine to eighty per cant and do, put and close lid in the appropriate vessel and run through, section is dried again.

4. Endothelium Corneum Gigeriae Galli, Fructus Gardeniae parch respectively.Earlier at the built-in sand of frying pan, the intense fire heating will be propagandized through the Endothelium Corneum Gigeriae Galli of big or small stepping after 5-10 minute in batches during the parch Endothelium Corneum Gigeriae Galli, and curling to bubbling is yellow, and it is standby to take out shakeout; Fructus Gardeniae is directly fried to coke black.

5. Cortex Phellodendri, Fructus Toosendan, Semen Plantaginis, Rhizoma Alismatis do the salt stir-fry respectively.Cortex Phellodendri is cleaned, shredding, dry back salt and fry; Fructus Toosendan cleave in two, salt are fried to coke yellow; Semen Plantaginis is made popular with slow fire, with spilling with stir-fry, fries dried with Sal to moisture; Rhizoma Alismatis is mixed the back thoroughly with saline solution and fries dried with slow fire.Per kilogram medical material Sal 0.01Kg-0.02Kg.

6. Fructus Aurantii makes parched with bran.Fructus Aurantii is cleaned, cuts into slices, dries, fry to being yellow with Testa Tritici and take out, sieve removes bran.

7. Radix Bupleuri is made vinegar system.Radix Bupleuri is cleaned, cuts into slices, dried, spray, mix thoroughly, treat that moisture is exhausted interior the stir-fry with slow fire of rearmounted pot and does with vinegar.Per kilogram Radix Bupleuri vinegar 0.0125Kg.

8. rhubarb tablets is made processed with wine.Wine is sprayed on rhubarb tablets, mixes thoroughly, it is dried with the slow fire stir-fry to treat that moisture is exhausted in the rearmounted pot.Per kilogram Radix Et Rhizoma Rhei wine 0.0125Kg.

Above each medicated powder through the initial processing and the process of preparing Chinese medicine is broken, cross 100 mesh sieves and be the powder finished product, put dry ventilation and preserve standby.Each oral 10-15g that is grown up, every day 3 times.

Embodiment 2 makes electuary

Take by weighing following 24 kinds of medicine dry products: the membrane of a chicken's gizzard 1200g desmodium 900g Lygodium japonicum 900g giant knotweed 700g felwort 600g sweet wormwood 500g Artemisia capillaris 600g root of large-flowered skullcap 500g golden cypress 400g cape jasmine 400g root tuber of aromatic turmeric 300g Fructus Aurantii 350g Armstrong 250g root bark of tree peony 300g radix paeoniae rubrathe 350g plantain seed 250g costus root 300g Fructus meliae toosendan 350g Poria cocos 250g rhizoma alismatis 100g umbellate pore furgus 200g pawpaw 200g RADIX BUPLEURI SCORZONERAEFOLII 200g rheum officinale 150g

Above medicine total amount is 10250 grams.

Preparation method:

Method by embodiment 1 is carried out the initial processing and the process of preparing Chinese medicine to each medicine, pulverizes the back high pressure and decocts 3 times, decocts 1-2 hour at every turn, gets each time decoction liquor and merges, and filters, and is condensed into graininess and is finished product.Each oral 6-10g that is grown up, every day 3 times.

Embodiment 3 makes oral liquid

Take by weighing 24 kinds of basic recipe medicines, be equipped with Radix Glycyrrhizae again, totally 25 kinds, each medicine dry product weight is: Endothelium Corneum Gigeriae Galli 900g Herba Lysimachiae 600g Spora Lygodii 600g Rhizoma Polygoni Cuspidati 500g Radix Gentianae 500g Herba Artemisiae Annuae 400g Herba Artemisiae Scopariae 400g Radix Scutellariae 350g Cortex Phellodendri 300g Fructus Gardeniae 300g Radix Curcumae 200g Fructus Aurantii 250g Herba Polygoni Avicularis 200g Cortex Moutan 240g Radix Paeoniae Rubra 200g Semen Plantaginis 240g Radix Aucklandiae (Radix Vladimiriae) 200g Fructus Toosendan 200g Poria 100g Rhizoma Alismatis 120g Polyporus 150g Fructus Chaenomelis 150g Radix Bupleuri Scorzonerifolii 200g Radix Et Rhizoma Rhei 200g Radix Glycyrrhizae 500g

Above medicine total amount is 8000 grams.

Preparation method:

Method by embodiment 1 is carried out the initial processing and the process of preparing Chinese medicine to each medicine, pulverizes the back high pressure and decocts 3 times, decocts 1-2 hour at every turn, gets each time decoction liquor and merges, and filters, and concentrates, and the finished product total amount is 15000ml.In every capacity 15-20ml of packing vial.Each oral 1 of adult, every day 3 times.

Embodiment 4 makes water pill

Select the medicine with embodiment 3 same breed, identical weight for use, by the method for embodiment 1 each medicine is carried out the initial processing and the process of preparing Chinese medicine, pulverize the back and cross 400 order dusting covers, the big piller of the general one-tenth Semen phaseoli radiati of water is finished product.Each oral 10-15g that is grown up, every day 3 times.

Each dosage form of medicine of the present invention is applicable to multi-section position calculus such as liver, gallbladder, kidney, ureter, bladder.Use through clinical hundreds of examples, effective percentage is more than 90%.Angor is frequently sent out the author generally in medication pain disappearance after 5 days.The less calculus of volume generally disappears in week at 2-3.Take pharmaceutical preparation of the present invention and do not have bad side effect.

Medicine of the present invention also has certain therapeutical effect to other multiple diseases of liver, gallbladder, kidney, as various hepatitis, fatty liver, cholecystitis, renal insufficiency etc.

Claims (2)

1. treat calculous medicine for one kind, it is characterized in that, its component comprises, Endothelium Corneum Gigeriae Galli Herba Lysimachiae Spora Lygodii Rhizoma Polygoni Cuspidati Radix Gentianae Herba Artemisiae Annuae Herba Artemisiae Scopariae Radix Scutellariae phellodendron and gardenia Radix Curcumae Fructus Aurantii Herba Polygoni Avicularis Cortex Moutan Radix Paeoniae Rubra Semen Plantaginis Radix Aucklandiae (Radix Vladimiriae) Fructus Toosendan Poria Rhizoma Alismatis Polyporus Fructus Chaenomelis Radix Bupleuri Scorzonerifolii Radix Et Rhizoma Rhei

2. medicine according to claim 1, it is characterized in that, each component dry product percentage by weight is Endothelium Corneum Gigeriae Galli 15-20% Herba Lysimachiae 12-16% Spora Lygodii 12-16% Rhizoma Polygoni Cuspidati 8-12% Radix Gentianae 8-12% Herba Artemisiae Annuae 6-10% Herba Artemisiae Scopariae 6-10% Radix Scutellariae 5-8% Cortex Phellodendri 5-8% Fructus Gardeniae 5-8% Radix Curcumae 4-6% Fructus Aurantii 4-6% Herba Polygoni Avicularis 4-6% Cortex Moutan 4-6% Radix Paeoniae Rubra 4-6% Semen Plantaginis 4-6% Radix Aucklandiae (Radix Vladimiriae) 4-6% Fructus Toosendan 4-6% Poria 2-4% Rhizoma Alismatis 2-4% Polyporus 2-4% Fructus Chaenomelis 2-4% Radix Bupleuri Scorzonerifolii 2-4% Radix Et Rhizoma Rhei 2-4%