CN103100051B - Traditional Chinese medicine composition for treating acute or chronic hepatitis and hepatosplenomegaly, and inhibiting liver cancer - Google Patents
Traditional Chinese medicine composition for treating acute or chronic hepatitis and hepatosplenomegaly, and inhibiting liver cancer Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the materials in parts by weight: 6-15 parts of radix bupleuri, 6-15 parts of rhizoma cimicifugae, 15-20 parts of astragalus mongholicus, 6-15 parts of root of red-rooted salvia, 6-15 parts of rhizoma alismatis, 6-15 parts of radix curcumae, 6-15 parts of oriental wormwood, 6-15 gardenia jasminoides, 6-15 rheum officinale, 15-20 parts of keel, 15-20 parts of oyster, and 2-4 parts of liquorice. The traditional Chinese medicine composition is the medicament for treating acute or chronic hepatitis and hepatosplenomegaly, and inhibiting liver cancer. The traditional Chinese medicine composition with significant in curative effect and low in cost for treating acute or chronic hepatitis and hepatosplenomegaly, and inhibiting liver cancer is provided by the invention on the basis of the principle of syndrome differentiation treatment of the traditional Chinese medicine; the conditions of excess and deficiency of yin and yang inside an organism are improved from pathological mechanisms of liver and spleen; spleen and stomach, and vital energy and blood of liver and kidney are adjusted, so as to become camp and smooth; after trace mineral element inside the medicament enters a human body, the organism can absorb effective ingredients to participate into human metabolism; and the balance of yin and yang, internal organs and vital energy and blood of the human body are conditioned on the whole; and elimination of illnesses and strengthening of foundation are achieved.
Description
Technical field
The present invention relates to field of medicaments, particularly the Chinese medicine composition for the treatment of acute, chronic hepatitis, hepatosplenomegaly and inhibition hepatocarcinoma.
Background technology
Hepatitis, typically refers to by multiple paathogenic factor, as virus, antibacterial, parasite, chemical toxicant, medicine, poisonous substance and ethanol etc., infringement liver, is damaged the cell of liver, and the function of liver suffers damage, cause a series of malaise symptoms of health, and liver function index is abnormal.Hepatitis refers to because a variety of causes causes hepatic necrosis, and abnormal liver function can be divided into acute hepatitis and chronic hepatitis, and the main distinction is pathogenesis.Acute hepatitis refers to that the general course of disease is no more than 6 months because infection hepatitis virus causes hepatic lesions; Mostly chronic hepatitis be by acute hepatitis b, and the acute hepatitis C course of disease surpasses to develop and forms half a year.In addition, chronic hepatitis has also comprised that those are not that viral reason causes, but clinical manifestation is chronic hepatitis patient, comprises Patients with Fatty Liver, drug induced hepatitis patient etc.
One of pathogenesis of hepatosplenomegaly is exactly abnormal liver function, and especially chronic anaemia patient, is prone to hepatosplenomegaly.Acute hepatitis also may there is in early days liver spleen silght enlargement, to convalescent period liver spleen generally can recover normally, but merge hemolytic anemia, may make liver spleen continue enlargement.The pathological manifestations of hepatosplenomegaly is that liver and spleen all increase.Liver spleen generally can not touch under rib, and when visceroptosis or diaphragm decline or dark when air-breathing, liver spleen could be touched, but is no more than 1cm under rib, and quality is softer.Hepatosplenomegaly is common in the diseases such as chronic hepatitis, typhoid fever, schistosomicide, liver cirrhosis are early stage, leukemia.
If self health status and living habit are paid no heed to, long-term abnormal liver function can cause liver to occur exacerbated disease, even causes liver to occur malignant tumor, i.e. said hepatocarcinoma.Hepatocarcinoma refers to the malignant tumor that betides liver, comprises two kinds of primary hepatocarcinoma and secondary liver cancers, and the hepatocarcinoma of the daily theory of people refers to primary hepatocarcinoma more.Primary hepatocarcinoma is one of modal malignant tumor clinically, and according to recent statistics, the annual new liver cancer patient approximately 600,000 in the whole world, occupies the 5th of malignant tumor.Primary hepatocarcinoma is pressed cell typing, can be divided into Hepatocellular carcinoma, intrahepatic cholangiocarcinoma and mixed carcinoma of liver.By the form of tumor, can be divided into nodular type, massive type and diffuse type.Primary hepatocarcinoma belongs to high morbidity in China, and China is hepatitis B big country, and how the hepatocarcinoma of China develops on the basis of hbv-liver cirrhosis, if do not add treatment, hepatitis B also can be converted into hepatocarcinoma.China's onset of liver cancer number accounts for the more than half of the whole world at present, accounts for 55% of global hepatocarcinoma patient, has become a large killer of serious threat China people health and lives, and its danger can not look down upon.
Modern medicine, to clinical a certain symptom treatment, is often difficult to produce a desired effect, and can not find suitable Therapeutic Method.Various hepatitis diseases, because its cause of disease is complicated, the course of disease is longer, without specific medicament, western medical treatment poor effect, toxic and side effects is many.Although various Western medicine preparations are successful in a short time, preparation is expensive, needs long-term taking to maintain treatment, and patient's economic pressures are large.During as some interferons Drug therapy hepatitis, short-term is alleviated to disease effect remarkable, but long-term taking can produce the side effect such as body anti-infection ability reduction, and can not prevent recurrence, easily bounce-back.Therefore, for hep disease, seeing a doctor in tcm treatment according to syndrome differentiation is desirable thinking, although conventional Chinese medicinal formulae and dosage form has certain curative effect at present, and neither be very desirable.Crowd's situation that various Chinese medicinal formulaes may be limited to concrete observation is different, and the clinical observation of long-term larger case load is not enough, causes curative effect very unstable, is difficult to promote and fixing prescription.
These situations show, existing medicine, for treatment hepatitis disease, is specially acute, chronic hepatitis, hepatosplenomegaly, and the inhibition to hepatocarcinoma, and Western medicine toxic and side effects used is large, easily bounce-back, and disturb the physiological function of each system of whole body; General facing with Chinese medicine is long the course for the treatment of, and DeGrain, is unfavorable for the reparation of patient physiological and psychic trauma.So a kind of evident in efficacy, stable in the urgent need to developing, and toxic and side effects is little, inexpensive easy-to-use pharmaceutical preparation.
Summary of the invention
Object of the present invention is exactly for the above-mentioned problem that existing treatment liver and spleen disease exists in clinical, and a kind of convenient effective Chinese medicine composition is provided.From the physiological characteristics of liver spleen and the pathology of liver and spleen disease, improve the situation of body abnormal liver function, the spleen and stomach regulating, Liver and kidney, make QI and blood battalion and unimpeded, and Chinese medicine all contains micro-mineral element in addition, enter after human body, for body, select its effective ingredient, and participate in human body metabolism, nurse one's health on the whole the balance of yin-Yang, internal organs, QI and blood, immunologic function is improved, get rid of illness and consolidate.Again because Chinese herbal medicine is less to human body side effect, and can treating both the principal and secondary aspects of a disease.Therefore, selecting treatment by Chinese herbs liver and spleen disease, is effective selection.Compare with existing medicine, the crude drug of Chinese medicine composition of the present invention easily obtains, and also has the function of heat-clearing and toxic substances removing, regulating qi to disperse stagnation, promoting the function of the gallbladder to alleviate jaundice, can be for the treatment to various liver and spleen diseases.Chinese medicine composition manufacture method of the present invention is simple, with low cost, without any toxic and side effects.
The present invention selects Radix Bupleuri, Rhizoma Cimicifugae, the Radix Astragali, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Radix Curcumae, Herba Artemisiae Scopariae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Os Draconis, Concha Ostreae, 12 kinds of Chinese medicines of Radix Glycyrrhizae to combine, the principle counteracting each other according to Chinese medicine, these medicines are effectively combined, make each efficacy of drugs produce synergism, nurse one's health on the whole the balance of yin-Yang, internal organs, QI and blood, to reach to get rid of illness, consolidate.Wherein, Radix Bupleuri toil is slightly cold, and has that expelling pathogenic factors from the exterior expels the heat-evil, a merit of dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Rhizoma Cimicifugae mildly bitter flavor and puckery, has the merit of the rash of delivering, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy; Radix Astragali sweet in the mouth, slightly warm in nature, energy invigorating the spleen and replenishing QI, tonifying the lung consolidating superficial resistance, inducing diuresis to remove edema; Radix Salviae Miltiorrhizae bitter in the mouth, micro-pungent, cold nature, be the medicine of the heart, spleen, liver, kidney blood system, has the effect of blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, removing heat from blood detumescence; Rhizoma Alismatis sweet in the mouth, cold, can diuretic, eliminating dampness by diuresis, expel the heat-evil; Radix Curcumae acrid in the mouth, bitter cold, can promoting QI circulation for relieving depression, removing heat from blood removing blood stasis with potent drugs; Herba Artemisiae Scopariae bitter in the mouth, pungent, be slightly cold, return spleen, stomach, liver, gallbladder meridian; Yellow Fructus Gardeniae bitter in the mouth is cold, for heat clearing away, pathogenic fire purging, removing heat from blood; Radix Et Rhizoma Rhei bitter in the mouth, cold, can attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances; Os Draconis sour in the mouth band is pungent, cool in nature, can heat-clearing and toxic substances removing, suppressing the hyperactive liver improving eyesight; Concha Ostreae can liver-invigorating detoxication, yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduce phlegm, softening the hard mass; Radix Glycyrrhizae sweet in the mouth, flat, can with middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
Drug dose of the present invention, counts: Radix Bupleuri 6-15 part, Rhizoma Cimicifugae 6-15 part, Radix Astragali 15-20 part, Radix Salviae Miltiorrhizae 6-15 part, Rhizoma Alismatis 6-15 part, Radix Curcumae 6-15 part, Herba Artemisiae Scopariae 6-15 part, Yellow Fructus Gardeniae 6-15 part, Radix Et Rhizoma Rhei 6-15 part, Os Draconis 15-20 part, Concha Ostreae 15-20 part, Radix Glycyrrhizae 2-4 part by weight.
Be preferably: 10 parts of Radix Bupleuri, 10 parts of Rhizoma Cimicifugaes, 18 parts of the Radixs Astragali, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Alismatis, 10 parts of Radix Curcumaes, 10 parts of Herba Artemisiae Scopariaes, 10 parts of Yellow Fructus Gardeniaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Os Draconis, 10 parts of Concha Ostreaes, 3 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is mainly the application in the medicine for the preparation for the treatment of acute, chronic hepatitis, hepatosplenomegaly, inhibition hepatocarcinoma.
The dosage form of Chinese medicine composition of the present invention is pill, powder, tablet, medical herbs decoction, powder, oral liquid or capsule preparations.
The preparation method of described Chinese medicine composition pill, comprises the following steps:
1) pulverize: described component is mixed by proportioning, drops into pulverizer and be ground into fine powder, to granularity be 80-100 order;
2) mixing: by step 1) gained fine powder input mixing and blending machine fully mixes;
3) dress ball: by step 2) the hollow soft gelatin capsule that loads on call, every net weight 0.5g.
The preparation method of the medical herbs decoction of described Chinese medicine composition, comprises the following steps:
1) get the raw materials ready: after described component is mixed by proportioning, pulverize each prepared slices of Chinese crude drugs, to it no longer than 5cm;
2) immersion: by step 1) gained is placed in the container of boiling medicine, and with cold water or warm water soaking 20-30 minute, water consumption was soaked powder 2-5cm, every 5 minutes, stirs once;
3) first pass is decocted medicinal herbs: by step 2) handy vigorous fire decocts to abundant boiling, transfers afterwards slow fire to and endures slowly, boils 20-30 minute.
4) decoct medicinal herbs for second time: until step 3) after gained medicinal liquid is cooling, add wherein warm water, soaked powder 1-3cm to the water surface, with vigorous fire, endure to abundant boiling, receive to slow fire and boil 20-30 minute;
5) medication: by step 4) medicinal liquid of gained is poured in cup, warm taking.
In the preparation process of medical herbs decoction, the used container of boiling medicine is terrine, marmite or stainless steel ware.Should not use iron pan, aluminum pot, so as not to Chinese medicine generation chemical reaction, affect medicinal effects.
The water used of boiling medicine is cold water, well water or spring water.Because cold water is generally boiled rear coolingly by tap water, and tap water is processed through bleaching powder, contains a large amount of chlorine elements, if directly boil with tap water, can impact the drug effect of Chinese medicine.Also can directly take well water or spring water boils, effect is better.
The present invention is based on the principle of tcm treatment according to syndrome differentiation, the Chinese medicine composition of a kind for the treatment of acute, chronic hepatitis evident in efficacy, with low cost, hepatosplenomegaly and inhibition hepatocarcinoma is provided.Pathology from liver spleen, improve the yin or yang excess situation partially declining in body, the QI and blood of the spleen and stomach regulating, Liver and kidney, make it battalion and unimpeded, trace quantity mineral substance element in spice enters after human body, body can absorb its effective ingredient and participate in human body metabolism, nurses one's health on the whole the balance of yin-Yang, internal organs and QI and blood, gets rid of illness and consolidates.
The specific embodiment
For many years, be the good effect of checking medicament of the present invention, inventor has carried out a large amount of tests, after being applicable to the patient of surrounding area, place, inventor residence, has received good effect.Situation according to accepting patient for medical treatment, is summarized as follows: accept patient's totally 112 examples for medical treatment, wherein, male patient's 64 examples, female patient 48 examples; Age 10-35 year 58 examples, 36-65 year 54 examples.Concrete, acute and chronic hepatitis patients 62 examples, hepatosplenomegaly patient's 36 examples, liver cancer patient 14 examples.
Now select part clinical experiment report as follows:
1. diagnosis and treatment evaluation criteria:
Recovery from illness: clinical symptom disappearance, drug withdrawal has no recurrence half a year.
Effective: symptom alleviates, but do not take a turn for the better completely.
Invalid: symptom is without obvious change.
2. diagnostic criteria: Syndrome Differentiation of Traditional Chinese Medicine, doctor trained in Western medicine check diagnosis effect.
3. Therapeutic Method: Chinese medicine composition of the present invention is made to pill, powder, tablet, medical herbs decoction, powder, oral liquid or capsule preparations.
4. medicinal method: dosage of the present invention depends on the factors such as concrete dosage form, patient age, body weight and health status.As medicinal guidance: get Radix Bupleuri 6-15g, Rhizoma Cimicifugae 6-15g, Radix Astragali 15-20g, Radix Salviae Miltiorrhizae 6-15g, Rhizoma Alismatis 6-15g, Radix Curcumae 6-15g, Herba Artemisiae Scopariae 6-15g, Yellow Fructus Gardeniae 6-15g, Radix Et Rhizoma Rhei 6-15g, Os Draconis 15-20g, Concha Ostreae 15-20g, Radix Glycyrrhizae 2-4g.Above-mentioned middle spice is mixed, after boiling by the preparation method of medical herbs decoction, take, sooner or later respectively once.
Preferably, the amount of each component is: Radix Bupleuri 10g, Rhizoma Cimicifugae 10g, Radix Astragali 18g, Radix Salviae Miltiorrhizae 10g, Rhizoma Alismatis 10g, Radix Curcumae 10g, Herba Artemisiae Scopariae 10g, Yellow Fructus Gardeniae 10g, Radix Et Rhizoma Rhei 10g, Os Draconis 10g, Concha Ostreae 10g, Radix Glycyrrhizae 3g.
5. clinical data gathers:
Below choosing model case illustrates:
Model case 1: grandson, man, 35 years old, complexion was dim, and color of the lip is livid purple, weak, and, there is vomiting in time and suffers from diarrhoea, and after examination in hospital, is diagnosed as chronic hepatitis.Through using following Chinese medicine, allot:
Radix Bupleuri 6g, Rhizoma Cimicifugae 6g, Radix Astragali 15g, Radix Salviae Miltiorrhizae 6g, Rhizoma Alismatis 6g, Radix Curcumae 6g, Herba Artemisiae Scopariae 6g, Yellow Fructus Gardeniae 6g, Radix Et Rhizoma Rhei 6g, Os Draconis 15g, Concha Ostreae 15g, Radix Glycyrrhizae 2g.After above-mentioned middle spice is mixed, after boiling by the preparation method of medical herbs decoction, take, sooner or later respectively once.
Take medicine after two weeks, patient recovers complexion; After one month, weak symptom disappears substantially, can do a little simple farm work; The three Ge Yuehoudao hospitals checks of taking medicine, thrombinogen, serum bilirubin and alaninyl transferring enzyme recover normal value; Continue to strengthen and take medicine after half a year, cure completely, do not recur again.
Model case 2: Zhang, female, 43 years old, dim complexion, became thin, weak, edema of lower limbs, the intestines and stomach malabsorption, or have symptoms such as polyphagia, polyuria, random thoughts headache, abdominal distention are diagnosed as hepatosplenomegaly after examination in hospital.Through using following Chinese medicine, allot:
Radix Bupleuri 15g, Rhizoma Cimicifugae 15g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 15g, Rhizoma Alismatis 15g, Radix Curcumae 15g, Herba Artemisiae Scopariae 15g, Yellow Fructus Gardeniae 15g, Radix Et Rhizoma Rhei 15g, Os Draconis 20g, Concha Ostreae 20g, Radix Glycyrrhizae 4g.After above-mentioned middle spice is mixed, after boiling by the preparation method of medical herbs decoction, take, sooner or later respectively once.
Take medicine after one week, patient's edema of lower limbs starts to disappear, and spirit takes a turn for the better, and complexion is recovered; After two weeks, take food smooth and easy, it is normal that defecation is recovered, and headache disappears; Take medicine one month, abdominal distention disappears obviously, energetic; Take medicine after two months, all diseases disappear, and do not recur again.
Model case 3: Liu, man, 32 years old, inappetence, weak, become thin, often sensation feel sick, vomiting, vexed swollen, the abdominal part upper right side persistence of epistaxis, abdominal part or intermittent pain sometimes, heating and edema that also can unknown cause.Afterwards, because continue to feel tired out weak and must not alleviate, so seek medical advice to hospital, be diagnosed as on inspection hepatocarcinoma.After hospitalization, above symptom is not obviously alleviated, and patient is because of the excessive recuperation of going home of economic pressures of hospitalization.After attempting having used following Chinese medicine to allot:
Radix Bupleuri 10g, Rhizoma Cimicifugae 10g, Radix Astragali 18g, Radix Salviae Miltiorrhizae 10g, Rhizoma Alismatis 10g, Radix Curcumae 10g, Herba Artemisiae Scopariae 10g, Yellow Fructus Gardeniae 10g, Radix Et Rhizoma Rhei 10g, Os Draconis 10g, Concha Ostreae 10g, Radix Glycyrrhizae 3g.After above-mentioned middle spice is mixed, after boiling by the preparation method of medical herbs decoction, take, sooner or later respectively once.
Take this medicine after one month, patient feels sick, the remission of vomiting, and appetite starts to recover; After two months, epistaxis is elongated interval time, and abdominal part is vexed swollen, and pain alleviates; After half a year, tired sense disappears, and muscle power is recovered substantially, does not occur heating and the edema of unknown cause again; Continue to strengthen and take medicine to 1 year, disease all disappears, and patient can normally participate in various physical works.
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement technical scheme of the present invention, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of claim scope of the present invention.
Claims (10)
1. Chinese medicine composition, it is characterized in that, by the former medicine of following weight portion, made: 6-15 parts of Radix Bupleuri, 6-15 parts of Rhizoma Cimicifugaes, 15-20 parts of the Radixs Astragali, 6-15 parts of Radix Salviae Miltiorrhizaes, 6-15 parts of Rhizoma Alismatis, 6-15 parts of Radix Curcumaes, 6-15 parts of Herba Artemisiae Scopariaes, 6-15 parts of Yellow Fructus Gardeniaes, 6-15 parts of Radix Et Rhizoma Rhei, 15-20 parts of Os Draconis, 15-20 parts of Concha Ostreaes, 2-4 parts, Radix Glycyrrhizae.
2. Chinese medicine composition according to claim 1, it is characterized in that, by the former medicine of following weight portion, made: 10 parts of Radix Bupleuri, 10 parts of Rhizoma Cimicifugaes, 18 parts of the Radixs Astragali, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Alismatis, 10 parts of Radix Curcumaes, 10 parts, 10 parts of Herba Artemisiae Scopariaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Os Draconis, 10 parts of Concha Ostreaes, 3 parts, Radix Glycyrrhizae.
3. the Chinese medicine composition described in claim 1 or 2 any one, the application in the medicine for the preparation for the treatment of acute, chronic hepatitis.
4. the Chinese medicine composition described in claim 1 or 2 any one, the application in the medicine for the preparation for the treatment of hepatosplenomegaly.
5. the Chinese medicine composition described in claim 1 or 2 any one, in the application for the preparation of suppressing in the medicine of hepatocarcinoma.
6. the preparation of the Chinese medicine composition described in claim 1 or 2 any one, is characterized in that, the dosage form of described Chinese medicinal composition preparation is pill, powder, tablet, medical herbs decoction, powder, oral liquid or capsule preparations.
7. the preparation of Chinese medicine composition according to claim 6, is characterized in that, the preparation method of described Chinese medicine composition pill, comprises the following steps:
1) pulverize: described component is mixed by proportioning, drops into pulverizer and be ground into fine powder, to granularity be 80-100 orders;
2) mix: step 1) gained fine powder is dropped into mixing and blending machine and fully mix;
3) dress ball: by step 2) the hollow soft gelatin capsule that loads on call, every net weight 0.5g.
8. the preparation of Chinese medicine composition according to claim 6, is characterized in that, the preparation method of the medical herbs decoction of described Chinese medicine composition, comprises the following steps:
1) get the raw materials ready: after described component is mixed by proportioning, pulverize each prepared slices of Chinese crude drugs, to it no longer than 5cm;
2) soak: step 1) gained is placed in to the container of boiling medicine, and with cold water or warm water soaking 20-30 minutes, water consumption was soaked powder 2-5cm, every 5 minutes, stirred once;
3) first pass is decocted medicinal herbs: by step 2) handy vigorous fire decocts to abundant boiling, transfers afterwards slow fire to and endures slowly, boils 20-30 minutes.
4) decoct medicinal herbs for second time: after step 3) gained medicinal liquid is cooling, add wherein warm water, soaked powder 1-3cm to the water surface, with vigorous fire, endure to abundant boiling, receive to slow fire and boil 20-30 minutes;
5) medication: the medicinal liquid of step 4) gained is poured in cup into warm taking.
9. the preparation of Chinese medicine composition according to claim 8, is characterized in that, described in the container of boiling medicine be terrine, marmite or stainless steel ware.
10. the preparation of Chinese medicine composition according to claim 8, is characterized in that, the water used of boiling medicine is cold water, well water or spring water.
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| CN1090193A (en) * | 1993-05-03 | 1994-08-03 | 孙志远 | The medicine and the production method of treatment diabetes |
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| CN1090193A (en) * | 1993-05-03 | 1994-08-03 | 孙志远 | The medicine and the production method of treatment diabetes |
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| Title |
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| 中医药治疗眩晕研究近况;李广浩等;《中国中医急症》;20040331;第13卷(第03期);177-179 * |
| 中西医结合治疗重症肝炎近况;盖欣等;《山东中医杂志》;19961130;第15卷(第11期);第526页第2栏倒数第1段第3-5行 * |
| 李广浩等.中医药治疗眩晕研究近况.《中国中医急症》.2004,第13卷(第03期), |
| 盖欣等.中西医结合治疗重症肝炎近况.《山东中医杂志》.1996,第15卷(第11期), |
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