CN103100045B

CN103100045B - Chinese herba preparation for treating forepart hepetocirrhosis

Info

Publication number: CN103100045B
Application number: CN201210559141.8A
Authority: CN
Inventors: 古友丽; 刘登富
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-12-20
Filing date: 2012-12-20
Publication date: 2014-09-17
Anticipated expiration: 2032-12-20
Also published as: CN103100045A

Abstract

The invention discloses a Chinese herba preparation for treating forepart hepetocirrhosis and belongs to the field of traditional Chinese medicine. The Chinese herba preparation is prepared from the following medicinal materials in parts by weight: 12 parts of herba lycopi, 10 parts of giant knot weed, 15 parts of codonopsis pilosula, 12 parts of Chinese yam, 10 parts of rhizoma sparganii, 9 parts of curcuma zedoary, 8 parts of gizzard pepsin, 10 parts of glossy privet fruit, 9 parts of placenta hominis, 12 parts of common vladimiria root, 12 parts of cassia twig, 8 parts of folium mori, 8 parts of rhizoma arisaematis and 12 parts of caulis spatholobi. The Chinese herba preparation is prepared from natural traditional Chinese medicines; the Chinese herba preparation has definite curative effect, is free of toxic and side effects, can effectively treat forepart hepetocirrhosis without recrudesce; and the effective rate is 98%.

Description

A kind of Chinese medicine preparation for the treatment of early stage liver cirrhosis

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of early stage liver cirrhosis, belong to the field of Chinese medicines.

Background technology

Early stage liver cirrhosis means clinically without any specific symptom or sign, liver function test Non Apparent Abnormality, but existing obvious pathological change on liver histological.Research both at home and abroad all confirms, early stage liver cirrhosis patient, and in liver, various collagen contents all increase to some extent, wherein take I, III Collagen Type VI deposition to increase as main.The I type of take end-age cirrhosis increases as main, take in early days III type as main, and along with the progress of hepatic fibrosis, I/III Collagen Type VI ratio increases to 1.59 by 1, and NTx fiber increases, and participates in the formation of connective tissue, and its reversibility is strong, is mainly seen in end-age cirrhosis.

The clinical symptoms performance of early stage liver cirrhosis mainly contains: loss of appetite, lose weight, and lassitude and weak, face is become thin, face is pitch-dark, diarrhoea, abdominal distention, stomachache, hepatalgia, irregular bleeding, endocrine function imbalance.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation that can effectively treat early stage liver cirrhosis, this Chinese medicine preparation determined curative effect, cheap and have no side effect.

Technical scheme of the present invention is:

Treating a Chinese medicine preparation for early stage liver cirrhosis, is to be made by the crude drug of following weight parts: Herba Lycopi 12, Rhizoma Polygoni Cuspidati 10, Radix Codonopsis 15, Rhizoma Dioscoreae 12, Rhizoma Sparganii 10, Rhizoma Curcumae 9, Endothelium Corneum Gigeriae Galli 8, Fructus Ligustri Lucidi 10, Placenta Hominis 9, Radix Vladimiriae 12, Ramulus Cinnamomi 12, Folium Mori 8, Rhizoma Arisaematis 8, Caulis Spatholobi 12.

Single dose dose (unit: gram): Herba Lycopi 12, Rhizoma Polygoni Cuspidati 10, Radix Codonopsis 15, Rhizoma Dioscoreae 12, Rhizoma Sparganii 10, Rhizoma Curcumae 9, Endothelium Corneum Gigeriae Galli 8, Fructus Ligustri Lucidi 10, Placenta Hominis 9, Radix Vladimiriae 12, Ramulus Cinnamomi 12, Folium Mori 8, Rhizoma Arisaematis 8, Caulis Spatholobi 12.

Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.

The pharmacological action of each Chinese medicine:

Herba Lycopi: bitter, pungent, tepor.Return liver, spleen channel.Effect with cure mainly: blood circulation promoting and blood stasis dispelling, line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis stomachache, edema.

Rhizoma Polygoni Cuspidati: micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Effect with cure mainly: expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea ， mass in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.

Radix Codonopsis: sweet, flat.Return spleen, lung meridian.Effect with cure mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.

Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Effect with cure mainly: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.

Rhizoma Sparganii: pungent, bitter, flat.Return liver, spleen channel.Effect with cure mainly: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.Yong Yu Disorder trace mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.

Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Effect with cure mainly: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Yong Yu mass in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.

Endothelium Corneum Gigeriae Galli: sweet, flat.Return spleen, stomach, small intestinal, urinary bladder channel.Effect with cure mainly: invigorating the stomach and promoting digestion, arresting seminal emission.For food stagnation, do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.

Fructus Ligustri Lucidi: sweet, bitter, cold.Return liver, kidney channel.Effect with cure mainly: nourishing liver, kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.

Placenta Hominis: sweet, salty, temperature.GUIXIN, lung, kidney channel.Effect with cure mainly: GUIXIN, lung, kidney channel.Thin for asthenia win, hectic fever due to YIN-deficiency night sweat, cough and asthma, lack of appetite is breathed hard, impotence and seminal emission, infertile hypogalactia.

Radix Vladimiriae: acrid, bitter, warm.Return board, stomach, large intestine, gallbladder meridian.Effect with cure mainly: promoting the circulation of QI to relieve pain.Be used for the abdominal distention and pain of uniting, borborygmus diarrhoea, tenesmus, two sides of body do not relax, liver and gall pain.

Ramulus Cinnamomi: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Effect with cure mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Folium Mori: sweet, bitter, cold.Return lung, Liver Channel.Effect with cure mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.

Rhizoma Arisaematis: bitter, pungent, temperature; Poisonous.Return lung, liver, spleen channel.Effect with cure mainly: drying dampness to eliminate phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, paralysis is dizzy, and middle wind-phlegm is stopped up, and mouthful limit is crooked, hemiplegia; Epilepsy, infantile convulsion, tetanus.Raw external treatment carbuncle, the snake bite and insect sting used.

Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Effect with cure mainly: enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.

The invention has the beneficial effects as follows: it is raw material that the present invention adopts natural Chinese medicine, determined curative effect and having no side effect, can effectively treat early stage liver cirrhosis and be difficult for recurrence, and effective percentage reaches 98%.

Below in conjunction with clinical trial and model case, the present invention is further described.

One, clinical trial

1, clinical data: choose at random 20-60 100 examples in year, its mean age is 43 years old, wherein, male's 49 examples, women's 51 examples.

2, Therapeutic Method: treatment group is taken medicine of the present invention, and every day is oral meal at twice.

3, efficacy assessment standard:

Recovery from illness: symptom all disappears, liver function detects recovers normal;

Effectively; Symptom is most of to disappear, and liver function detects and is clearly better;

Invalid: after treatment, nothing is improved.

4, therapeutic outcome: at clinical use medicine of the present invention, the 100 routine patients that take medicine, took medicine after two courses for the treatment of, and symptom is alleviated to some extent, takes medicine after 3 courses for the treatment of, and symptom is obviously improved.In the routine patient of clinical trial 100, recovery from illness 85 examples, effective 13 examples, total effective rate is 98%.

Two: model case

Case 1: Wang, man, 65 years old, patient in 2005 to 2010 the end of the year patient occur that health is tired, chronic problem, two weakness of the lower extremities, poor, unfavorable, dysuria, the hepatic region paroxysmal twinge sometimes of defecating of sleep, feeling of repletion, B ultrasonic shows: liver is little, and Echoenhance is inhomogeneous, be diagnosed as early stage liver cirrhosis, take after medicine two weeks of the present invention, above-mentioned symptom makes moderate progress, and continues to take medicine after 1 month, symptom all disappears, and liver function recovery is normal after testing.After 1 year, follow up a case by regular visits to, the state of an illness is without recurrence.

Case 2: in certain, female, 51 years old, patient occurred that without inducement fatigue and weak, appetite are low after the Spring Festival in 2011, spirit is poor, dyspnea; Lab testing: liver function AST:528u/l, ALT:632u/l, image pathological examination: hepatocyte edema, proliferation of fibrous tissue, portal area lymphocytic infiltration, it is obviously abnormal that liver function is looked in pseudolobuli formation, is diagnosed as early stage liver cirrhosis.Local therapeutic effect is bad, and liver function again and again, is taken medicine of the present invention after being introduced, takes medicine after 1 month, and above-mentioned symptom obviously improves, and continues to take medicine after 1 month, and symptom all disappears, and liver function detects recovers normal, after 1 year, follows up a case by regular visits to, and the state of an illness is without recurrence.

The specific embodiment

Embodiment

Proportioning (unit: gram): Herba Lycopi 12, Rhizoma Polygoni Cuspidati 10, Radix Codonopsis 15, Rhizoma Dioscoreae 12, Rhizoma Sparganii 10, Rhizoma Curcumae 9, Endothelium Corneum Gigeriae Galli 8, Fructus Ligustri Lucidi 10, Placenta Hominis 9, Radix Vladimiriae 12, Ramulus Cinnamomi 12, Folium Mori 8, Rhizoma Arisaematis 8, Caulis Spatholobi 12.

Claims

1. treat a Chinese medicine preparation for early stage liver cirrhosis, it is characterized in that being made by the crude drug of following weight parts: Herba Lycopi 12, Rhizoma Polygoni Cuspidati 10, Radix Codonopsis 15, Rhizoma Dioscoreae 12, Rhizoma Sparganii 10, Rhizoma Curcumae 9, Endothelium Corneum Gigeriae Galli 8, Fructus Ligustri Lucidi 10, Placenta Hominis 9, Radix Vladimiriae 12, Ramulus Cinnamomi 12, Folium Mori 8, Rhizoma Arisaematis 8, Caulis Spatholobi 12.