CN103083582B - 一种治疗高血脂的药物 - Google Patents
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Abstract
Description
模型对照组 | 阳性对照组 | 实施例1组 | 实施例2组 | 实施例3组 | |
n | 15 | 15 | 15 | 15 | 15 |
TC | 2.84±0.36 | 2.04±0.21 | 2.08±0.24 | 2.15±0.30 | 2.09±0.26 |
TG | 1.87±0.43 | 1.09±0.28 | 1.21±0.29 | 1.37±0.36 | 1.25±0.31 |
HDL-C | 2.14±0.65 | 2.93±0.85 | 2.94±0.76 | 2.98±0.72 | 2.97±0.77 |
LDL-C | 0.66±0.23 | 0.57±0.16 | 0.29±0.16 | 0.34±0.15 | 0.32±0.17 |
痊愈(例%) | 显效(例%) | 有效(例%) | 无效(例%) | 有效率(%) | |
治疗后1疗程 | 19(19) | 37(37) | 29(29) | 15(15) | 85 |
治疗后2疗程 | 52(52) | 19(19) | 15(15) | 14(14) | 86 |
治疗后3疗程 | 73(73) | 10(10) | 9(9) | 8(8) | 92 |
治疗后4疗程 | 93(93) | 2(2) | 3(3) | 2(2) | 98 |
Claims (4)
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103734431A (zh) * | 2014-01-13 | 2014-04-23 | 江苏海昇药业有限公司 | 一种降脂代用茶配方及其制备方法 |
CN103735603B (zh) * | 2014-02-11 | 2016-08-31 | 武汉市元大生物科技有限公司 | 一种复方降脂软胶囊及其制备方法 |
CN104857506A (zh) * | 2015-05-15 | 2015-08-26 | 张家港市五湖新材料技术开发有限公司 | 一种降血脂中药及制备方法 |
CN105125965A (zh) * | 2015-10-24 | 2015-12-09 | 黄宇松 | 一种治疗高血脂的药剂 |
CN105943583B (zh) * | 2016-06-07 | 2020-05-22 | 上海交通大学 | 青蒿红曲组合物及其用途 |
CN108713673A (zh) * | 2018-04-03 | 2018-10-30 | 徐州工程学院 | 一种药食同源的保健品及其制备方法 |
CN109288994A (zh) * | 2018-12-10 | 2019-02-01 | 李晓屏 | 一种降脂通络丸药方及其制备工艺 |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101020028A (zh) * | 2006-11-11 | 2007-08-22 | 刘光辉 | 一种治疗心脑血管疾病的中药 |
CN101214352A (zh) * | 2007-01-05 | 2008-07-09 | 闫淑丽 | 一种治疗高脂血症的中药 |
CN101496872A (zh) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术(北京)有限责任公司 | 一种降血脂的中药组合物及其制备方法 |
CN101530558A (zh) * | 2008-03-13 | 2009-09-16 | 北京天科仁祥医药科技有限公司 | 一种用于降血脂的中药 |
CN101623089A (zh) * | 2008-07-08 | 2010-01-13 | 刘泳宏 | 一种五色养脏降脂减肥果蔬茶饮品及制作方法 |
CN101683462A (zh) * | 2008-09-23 | 2010-03-31 | 天津市中宝制药有限公司 | 一种疏肝补肾中药组合物 |
CN102114096A (zh) * | 2010-06-24 | 2011-07-06 | 吕奎荣 | 一种治疗心脑血管的中药口服冲剂 |
CN102188560A (zh) * | 2010-03-08 | 2011-09-21 | 张锡林 | 中药治疗高血脂 |
CN102335395A (zh) * | 2011-10-12 | 2012-02-01 | 赵全成 | 预防高血压、缺血性心脑疾病的保健酒及其制备方法 |
CN102335339A (zh) * | 2011-10-19 | 2012-02-01 | 成都绿迪科技有限公司 | 一种治疗高脂血症的中药制剂 |
CN102343053A (zh) * | 2011-10-19 | 2012-02-08 | 成都绿迪科技有限公司 | 一种治疗高脂血症的中药 |
CN102488772A (zh) * | 2011-12-21 | 2012-06-13 | 许从玉 | 一种预防或治疗高血脂症的中药组合物 |
CN102526639A (zh) * | 2012-03-13 | 2012-07-04 | 常熟华港制药有限公司 | 治疗高血脂症的中药组合物及其制备方法 |
-
2013
- 2013-02-05 CN CN201310062360.XA patent/CN103083582B/zh not_active Expired - Fee Related
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101020028A (zh) * | 2006-11-11 | 2007-08-22 | 刘光辉 | 一种治疗心脑血管疾病的中药 |
CN101214352A (zh) * | 2007-01-05 | 2008-07-09 | 闫淑丽 | 一种治疗高脂血症的中药 |
CN101496872A (zh) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术(北京)有限责任公司 | 一种降血脂的中药组合物及其制备方法 |
CN101530558A (zh) * | 2008-03-13 | 2009-09-16 | 北京天科仁祥医药科技有限公司 | 一种用于降血脂的中药 |
CN101623089A (zh) * | 2008-07-08 | 2010-01-13 | 刘泳宏 | 一种五色养脏降脂减肥果蔬茶饮品及制作方法 |
CN101683462A (zh) * | 2008-09-23 | 2010-03-31 | 天津市中宝制药有限公司 | 一种疏肝补肾中药组合物 |
CN102188560A (zh) * | 2010-03-08 | 2011-09-21 | 张锡林 | 中药治疗高血脂 |
CN102114096A (zh) * | 2010-06-24 | 2011-07-06 | 吕奎荣 | 一种治疗心脑血管的中药口服冲剂 |
CN102335395A (zh) * | 2011-10-12 | 2012-02-01 | 赵全成 | 预防高血压、缺血性心脑疾病的保健酒及其制备方法 |
CN102335339A (zh) * | 2011-10-19 | 2012-02-01 | 成都绿迪科技有限公司 | 一种治疗高脂血症的中药制剂 |
CN102343053A (zh) * | 2011-10-19 | 2012-02-08 | 成都绿迪科技有限公司 | 一种治疗高脂血症的中药 |
CN102488772A (zh) * | 2011-12-21 | 2012-06-13 | 许从玉 | 一种预防或治疗高血脂症的中药组合物 |
CN102526639A (zh) * | 2012-03-13 | 2012-07-04 | 常熟华港制药有限公司 | 治疗高血脂症的中药组合物及其制备方法 |
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