CN103080329B - 含有半乳寡聚糖的组合物及其生产方法 - Google Patents

含有半乳寡聚糖的组合物及其生产方法 Download PDF

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Publication number
CN103080329B
CN103080329B CN201180035455.1A CN201180035455A CN103080329B CN 103080329 B CN103080329 B CN 103080329B CN 201180035455 A CN201180035455 A CN 201180035455A CN 103080329 B CN103080329 B CN 103080329B
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gal
galactosyl
enzyme
donor
mixture
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Chinese (zh)
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CN103080329A (zh
Inventor
汉斯·贝特尔森
魏谢 彼得·朗堡
彼得·朗堡魏谢
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International N&H Denmark ApS
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Arla Foods AMBA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pediatric Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
CN201180035455.1A 2010-07-19 2011-07-19 含有半乳寡聚糖的组合物及其生产方法 Expired - Fee Related CN103080329B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36556010P 2010-07-19 2010-07-19
US61/365,560 2010-07-19
EP10169981.7 2010-07-19
EP10169981 2010-07-19
PCT/EP2011/062355 WO2012010597A1 (en) 2010-07-19 2011-07-19 Galacto-oligosaccharide-containing composition and a method of producing it

Publications (2)

Publication Number Publication Date
CN103080329A CN103080329A (zh) 2013-05-01
CN103080329B true CN103080329B (zh) 2016-08-03

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CN201180035455.1A Expired - Fee Related CN103080329B (zh) 2010-07-19 2011-07-19 含有半乳寡聚糖的组合物及其生产方法

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Country Link
US (2) US20130189746A1 (enExample)
EP (1) EP2596113B1 (enExample)
JP (1) JP2013530719A (enExample)
KR (1) KR20130041953A (enExample)
CN (1) CN103080329B (enExample)
AR (1) AR082261A1 (enExample)
BR (1) BR112013001109A2 (enExample)
CA (1) CA2805997A1 (enExample)
DK (1) DK2596113T3 (enExample)
EA (1) EA201300150A1 (enExample)
MX (1) MX348325B (enExample)
NZ (1) NZ607149A (enExample)
WO (1) WO2012010597A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2620506A1 (en) * 2012-01-25 2013-07-31 Arla Foods Amba Method of producing a galacto-oligosaccharide-containing composition
WO2013182686A1 (en) * 2012-06-08 2013-12-12 Dupont Nutrition Biosciences Aps Polypeptides having transgalactosylating activity
WO2013190530A1 (en) * 2012-06-22 2013-12-27 Glycom A/S Modified galactooligosaccharides
CA2913393A1 (en) 2013-05-24 2014-11-27 General Mills, Inc. Food products with yogurt whey
EP3446569A1 (en) 2013-12-11 2019-02-27 DuPont Nutrition Biosciences ApS A method for preparing a dairy product having a stable content of galacto-oligosaccharide(s)
KR101595014B1 (ko) 2014-02-21 2016-02-18 재단법인 임실치즈과학연구소 갈락토올리고당 생성 유산균주를 이용한 발효유의 제조방법
AU2015341682A1 (en) * 2014-11-07 2017-05-11 Dupont Nutrition Biosciences Aps Method of generating a saccharide containing a galactose and a fructose moiety employing enzyme with transgalactosylating activity
DK3214942T3 (da) 2014-11-07 2021-05-25 Dupont Nutrition Biosci Aps Rekombinant værtscelle, der udtrykker beta-galactosidase- og/eller transgalactosyleringsaktivitet, der er deficient i mannanase, cellulase og pektinase
EP3607097B1 (en) 2017-04-07 2023-06-21 DuPont Nutrition Biosciences ApS Bacillus host cells producing beta-galactosidases and lactases in the absence of p-nitrobenzylesterase side activity
GB201805577D0 (en) * 2018-04-04 2018-05-16 Optibiotix Health Ltd Prebiotic compositions and methods of production thereof
MX2024004006A (es) 2021-09-30 2024-04-22 Int N&H Denmark Aps Metodo para reducir azucar en productos alimenticios.
CN118695783A (zh) 2021-11-12 2024-09-24 凯里集团国际有限公司 生产乳制品的方法
CN120957606A (zh) 2023-03-29 2025-11-14 国际营养与健康丹麦有限公司 经由优选原位产生的α-葡聚糖改变食料质地的方法
WO2026015598A2 (en) 2024-07-11 2026-01-15 International N&H Denmark Aps Method to provide improved texture and stable sucrose levels in foodstuff with glucosyltransferase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001090317A3 (en) * 2000-05-26 2002-04-25 Arla Foods Amba Beta-galactosidase isolated from a bifidobacterium
CN101341255A (zh) * 2005-11-08 2009-01-07 科拉萨多公司 生产寡糖的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1205555A1 (de) * 2000-11-08 2002-05-15 Solvent Innovation GmbH Enzymkatalyse in Gegenwart ionischer Flüssigkeiten
DE602004006133T3 (de) * 2003-06-30 2014-12-24 Clasado Inc. Neue galactooligosaccharidzusammensetzung und herstellung davon

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001090317A3 (en) * 2000-05-26 2002-04-25 Arla Foods Amba Beta-galactosidase isolated from a bifidobacterium
CN101341255A (zh) * 2005-11-08 2009-01-07 科拉萨多公司 生产寡糖的方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Purifiationg and properties of aβ-D-galactosidase from Bifidobacterium bifidum exhibiting a transgalactosylation reaction;Vincent Dumortier et al;《Biotechnol Appl.Biochem》;19940101;第19卷(第19期);说明书实施例1-3、核苷酸和氨基酸序列表 *

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Publication number Publication date
KR20130041953A (ko) 2013-04-25
WO2012010597A1 (en) 2012-01-26
MX348325B (es) 2017-06-06
CA2805997A1 (en) 2012-01-26
MX2013000793A (es) 2014-04-30
EP2596113B1 (en) 2018-09-12
CN103080329A (zh) 2013-05-01
US20130189746A1 (en) 2013-07-25
JP2013530719A (ja) 2013-08-01
EA201300150A1 (ru) 2013-08-30
AU2011281663A1 (en) 2013-03-07
US20160369313A1 (en) 2016-12-22
BR112013001109A2 (pt) 2016-05-24
EP2596113A1 (en) 2013-05-29
NZ607149A (en) 2014-12-24
AR082261A1 (es) 2012-11-21
DK2596113T3 (en) 2019-01-07

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