CN103071082A

CN103071082A - Traditional Chinese medicine composition for treating chronic nephritis

Info

Publication number: CN103071082A
Application number: CN2012105550206A
Authority: CN
Inventors: 陈柏林
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-12-04
Filing date: 2012-12-04
Publication date: 2013-05-01

Abstract

The invention relates to a traditional Chinese medicine composition for treating chronic nephritis. The traditional Chinese medicine composition for treating chronic nephritis comprises ant, cicada slough, stiff silkworm, pseudo-ginseng, glabrous greenbrier rhizome, milkvetch root, heterophylly falsestarwort root, semen cuscutae, cogon grass rhizome, dandelion, Tokyo violet herb, motherwort herb, oriental waterplantain rhizome, asiatic cornelian cherry fruit, red sage root, largehead atractylodes rhizome, coix seed, hedyotis, teasel, plantain, herba pyrrosiae, epimedium and raw rhubarb. The traditional Chinese medicine composition for treating chronic nephritis has the effects of supporting right and securing the root, clearing heat and draining dampness, removing stasis and transforming turbidity, and invigorating spleen and nourishing kidney. The traditional Chinese medicine composition can control a focus, block an antigen, adjust cellular immunity, improve local blood microcirculation and improve permeability of glomerular capillary. The traditional Chinese medicine composition can effectively control and dissolve blood coagulation and sediments in the peritubular capillary, reduce (protein, erythrocyte, leucocyte and tube-type exudation) inflammation damage and realize chronic nephritis treatment.

Description

A kind of Chinese medicine composition for the treatment of chronic nephritis

Technical field: the present invention relates to traditional Chinese medical science patent medicine, especially a kind of Chinese kmedicine bolus preparation for the treatment of chronic nephritis.

Background technology: chronic glomerulonephritis is called for short chronic nephritis, it is the one group of immune inflammation disease that is primary in glomerule that is caused by many reasons, it changes in early days is basement membrane or phase film hypertrophy, or the focal nephritis change, the primary disease course of disease is longer, and clinical manifestation typical case person has hematuria, albuminuria, cylinderuria, edema, hypertension etc.; The lighter can only have a small amount of albuminuria and microscopic hematuria; Anemia can appear in severe one, and serious hypertension also can develop into renal failure gradually.Primary disease belongs to the category of Chinese medicine " edema " " asthenia " " lumbago ".At present western medicine and medical practitioners treatment is main mainly with antiinflammatory, and the traditional Chinese medical science is then debated disease executing and controlled.

Summary of the invention: the present invention is the preparation agent of a kind of animal drugs and Chinese herbal medicine, be exclusively used in the oral administration for treating chronicity glomerulonephritis, belong to the innovation and creation class, a kind of Chinese medicine composition for the treatment of chronic nephritis of the present invention is made of by weight following 24 flavor Chinese crude drugs: Formica fusca, Periostracum Cicadae, Bombyx Batryticatus, Radix Notoginseng, Rhizoma Smilacis Glabrae, the Radix Astragali, Radix Pseudostellariae, Semen Cuscutae, Rhizoma Imperatae, Herba Taraxaci, Herba Violae, Herba Leonuri, Rhizoma Alismatis, Fructus Corni, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Coicis, Herba Hedyotidis Diffusae, Radix Dipsaci, Herba Plantaginis, Folium Pyrrosiae, Herba Epimedii, Radix Et Rhizoma Rhei.Many and the lung spleen kidney three addle liquid metabolism of its pathogeny of chronic nephritis, and the lung kidney to have solid Tibetan malfunction under one's command relevant.Chronic nephritis spleen deficiency of kidney-QI of a specified duration, the weary power of row water, cause retention of water-damp in the body, water retention is vapour lock then, and the stagnation of QI is blood stasis then, deficiency of vital energy blood vessels are unfavorable, thereby form the refreshing assorted disease of deficiency and excess, treatment is take strengthening vital QI to eliminate pathogenic factors as main, with the sweet temperature QI invigorating of the Radix Astragali, inducing diuresis to remove edema, Radix Pseudostellariae, the Rhizoma Atractylodis Macrocephalae, Formica fusca air making-up and spleen enlivening: the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Radix Notoginseng, Herba Leonuri yin nourishing removing heat from blood, removing stasis to stop bleeding; Herba Hedyotidis Diffusae, Herba Plantaginis, the clear profit of Herba Violae are subsided a swelling, damp eliminating is turbid; Semen Cuscutae, Radix Dipsaci, Herba Epimedii benefit controlling nocturnal emission with astringent drugs are got the meaning of " decreasing its essence of its kidney person benefit ", and all medicines share, tonify without causing stagnation, and invigorating middle warmer has to be had foster, pure and impure in logical, logical and just not to hinder.Thereby reach the spleen reinforcing kidney and solid protection healthy energy, the damp eliminating stasis of blood and lead heresy and go out, modern pharmacological research shows, the Radix Astragali, Radix Pseudostellariae, Semen Cuscutae, river Formica fusca, Radix Dipsaci etc. have the adjusting immunologic function, improve renal function, prevent that uremia from occuring.Herba Hedyotidis Diffusae, Herba Plantaginis have the inhibition allergy, reduce the infringement to kidney, are conducive to the recovery of renal function, and Radix Salviae Miltiorrhizae, Herba Leonuri are improved microcirculation, reduce platelet aggregation, and the drainage of Promote immunity complex is conducive to the reparation of pathological tissues.The specific embodiment: the invention will be further described below in conjunction with specific embodiment: a kind of preparation method for the treatment of the Chinese medicine composition of chronic nephritis of the present invention; Get Formica fusca 30g, Periostracum Cicadae 20g, Bombyx Batryticatus 20g, Radix Notoginseng 15g, Rhizoma Smilacis Glabrae 30g, Radix Astragali 30g, Radix Pseudostellariae 30g, Semen Cuscutae 20g, Rhizoma Imperatae 20g, Herba Taraxaci 20g, Herba Violae 20g, Herba Leonuri 30g, Rhizoma Alismatis 20g, Fructus Corni 20g, Radix Salviae Miltiorrhizae 15g, Rhizoma Atractylodis Macrocephalae 15g, Semen Coicis 30g, Herba Hedyotidis Diffusae 20g, Radix Dipsaci 15g, Herba Plantaginis 20g, Folium Pyrrosiae 15g, Herba Epimedii 15g, Radix Et Rhizoma Rhei 10g, general as ball take above-mentioned 24 flavor Chinese crude drugs water after selected drying and crushing is crossed 100 mesh sieves, large such as Semen phaseoli radiati, bottling is for subsequent use after the sterilization, whenever, take 6g day three times, morning, noon and afternoon after meal warm water send down, per 1 month was 1 course for the treatment of.The present invention has following advantages: strengthening the body resistance, and clearing away heat-damp and promoting diuresis, removing blood stasisization is turbid, the effects such as tonifying speen and tonifying kidney.The control focus, blocking-up antigen is regulated cellular immunization, improves the local blood microcirculation, improves the permeability of glomerular capillary.The control that is effective, the blood coagulation in the dissolving kidney blood capillary, deposition reduces the damage of (oozing out of albumen, erythrocyte, leukocyte, cast) inflammation, thereby reaches the purpose for the treatment of.

The present invention takes clinical observation by 320 routine patients with chronic glomerulonephritis.Simple hematuria person's (does not wait ERY+1～+ 4) 82 examples of simple proteins urine person 120 examples (+1～+ 4 does not wait) wherein, albuminuria hematuria person's 119 examples of holding concurrently have patient over half with edema in various degree in 320 routine patients with chronic glomerulonephritis.Taking 1-3 of the present invention after the course for the treatment of, total effective rate is 95%, and inefficiency only is that 2%, 3% case takes his medicine or therapy discontinued owing to other reason changes.

Model case:

Patient Xu certain, the woman, 56 years old, in first visit on June 15 in 2000, private prosecution was suffered from chronic nephritis more than 5 years, Relapse rate, recently increase the weight of, certain hospital did not once subtract with the hormonotherapy symptom, and edema is serious, renal function is measured three indexs and is all increased, 3 of ERY (+++) urine protein (+++) granular casts.Requirement is left hospital and is gone home to treat, and by the agency of is invited remaining diagnosis and treatment.First visit: card is seen shortness of breath and palpitation, spiritlessness and weakness, and shallow complexion, abdominal part swells, the lower abdomen generalized edema with distention of the chest and abdomen, edema of pair of lower extremities can not pressed aversion to cold and cold limbs, and tongue fur is light white, and indented tongue margin is off one's feed, and pulse condition is heavy unable late.Dialectical: deficiency of spleen-YANG and kidneyYANG, can not transmitting and distributing the fluids, decline of the fire from the gate of life can not the Wen Zhaosi branch.Side's medicine: take after taking juice with Radix Aconiti Lateralis Preparata 15g, Rhizoma Zingiberis 15g, 5 pieces in Fructus Jujubae, brown sugar 20g, Chinese kmedicine bolus agent of the present invention 6g/ time, every day potion, every dose is divided the morning, noon and afternoon to take for 3 times, pill 6g/ time is taken a course for the treatment of altogether.Two examine: edema of pair of lower extremities disappears, and sees that expression all take a favorable turn, and the readme diet increases, and pulse condition is superficially and silly strong, and thin and greasy fur is dialectical: accumulate the gasification function imbalance in the noxious dampness.Treatment: blood circulation promoting and blood stasis dispelling, detoxifcation dehumidifying, square medicine: continuing takes Chinese kmedicine bolus agent of the present invention 6g/ time, 3 times/days, takes altogether to accuse after two courses for the treatment of and heals.

Chen, the man, 55 years old, the peasant, in August, 2000 is medical, private prosecution nearly 20 days in certain hospital's hormonotherapy, every day 15 meticortens, the aobvious sx↑ of effect is invited remaining diagnosis and treatment after leaving hospital.

First visit: deep-slow pulse is held concurrently sliding unable, and card is seen shortness of breath and fatigue, lazy speech, and extremity are not warm, anuria and oliguria, the fear of cold inappetence, white and greasy fur, faint low voice is unable, Mental fatigue extremely, laboratory test report: ERY (+++), 3 of urine protein (+++) granular casts.

Dialectical: deficiency of spleen-YANG and kidneyYANG, cold and stagnate, the wet dipping of water, decline of the fire from the gate of life.

Treatment: tonifying speen and tonifying kidney, the temperatureization kidney yang, the dampness diuretic is opened entire kidney qi.

Side's medicine: take medicine pill of the present invention with Radix Aconiti Lateralis Preparata 15g, Rhizoma Zingiberis 15g, 5 pieces in Fructus Jujubae, brown sugar 20g, extracting juice, day potion divides to take for three times, and pill 6g/ time, is taken a course for the treatment of altogether by 3 times/days.

Two examine: patient's private prosecution diet increases, frequent micturition, and two edeam of legs disappear, and the self-induction of walking is freely.

Pulse condition: number has power, thin lingual fur concurrently.

Method: removing summer-heat noxious dampness, blood stasis dispelling relieving distension

Side's medicine: continuing takes Chinese kmedicine bolus agent chemical examination three courses for the treatment of of the present invention, and indices is all normal.

Lee, 12 years old, in December, 2000 was suffered from acute glomerulonephritis, lived certain hospital more than near month, and laboratory test report urine is for blood (+++) the full visual field of erythrocyte at that time, 2 in albumen (+++) cast cell, antibacterial is high, edema.Subtract greatly with all diseases of western medicine, ERY urine protein each (++), aobvious unstable during fashion, require to leave hospital.

First visit: it is very heavy that see certain laboratory test report January calendar year 2001, and children's's expression is fine, becomes thin, and frequent micturition is anxious, thirsty being off one's feed, and feverish sensation in the palms and soles, language is high.

Dialectical: as to invade the retention of damp-heat in the interior type in the damp pyretic toxicity.

Treatment: YIN nourishing, heat clearing away, pathogenic fire reducing, dampness removing, detoxifcation.

Side's medicine: Chinese kmedicine bolus agent of the present invention for oral administration, 3g/ time, 3 times/days, serve on 20 days, urine protein, ERY all disappears, after take again one month, follow up a case by regular visits to and do not recur in 4 years.

Claims

1. the present invention relates to a kind of Chinese medicine composition for the treatment of chronic nephritis, formed by the following traditional Chinese medicines material: Formica fusca 30g, Periostracum Cicadae 20g, Bombyx Batryticatus 20g, Radix Notoginseng 15g, Rhizoma Smilacis Glabrae 30g, Radix Astragali 30g, Radix Pseudostellariae 30g, Semen Cuscutae 20g, Rhizoma Imperatae 20g, Herba Taraxaci 20g, Herba Violae 20g, Herba Leonuri 30g, Rhizoma Alismatis 20g, Fructus Corni 20g, Radix Salviae Miltiorrhizae 15g, Rhizoma Atractylodis Macrocephalae 15g, Semen Coicis 30g, Herba Hedyotidis Diffusae 20g, Radix Dipsaci 15g, Herba Plantaginis 20g, Folium Pyrrosiae 15g, Herba Epimedii 15g, Radix Et Rhizoma Rhei 10g.