CN103059311B - 基于分子胶的aba型两亲性三嵌段共聚物及其用途 - Google Patents

基于分子胶的aba型两亲性三嵌段共聚物及其用途 Download PDF

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Publication number
CN103059311B
CN103059311B CN201210563824.0A CN201210563824A CN103059311B CN 103059311 B CN103059311 B CN 103059311B CN 201210563824 A CN201210563824 A CN 201210563824A CN 103059311 B CN103059311 B CN 103059311B
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China
Prior art keywords
pla
peg
compound
aba type
block copolymer
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CN201210563824.0A
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Chinese (zh)
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CN103059311A (zh
Inventor
杨晴来
龚兵
沈玉梅
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Shanghai Jiaotong University
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Shanghai Jiaotong University
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Priority to PCT/CN2013/088478 priority patent/WO2014094539A1/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/07—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from polymer solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2353/00—Characterised by the use of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
CN201210563824.0A 2012-12-21 2012-12-21 基于分子胶的aba型两亲性三嵌段共聚物及其用途 Active CN103059311B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201210563824.0A CN103059311B (zh) 2012-12-21 2012-12-21 基于分子胶的aba型两亲性三嵌段共聚物及其用途
PCT/CN2013/088478 WO2014094539A1 (fr) 2012-12-21 2013-12-04 Copolymère triséquencé du type aba à base de colle moléculaire, synthèse de celui-ci et utilisation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210563824.0A CN103059311B (zh) 2012-12-21 2012-12-21 基于分子胶的aba型两亲性三嵌段共聚物及其用途

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CN103059311A CN103059311A (zh) 2013-04-24
CN103059311B true CN103059311B (zh) 2014-11-19

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CN (1) CN103059311B (fr)
WO (1) WO2014094539A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103059311B (zh) * 2012-12-21 2014-11-19 上海交通大学 基于分子胶的aba型两亲性三嵌段共聚物及其用途
CN103396556B (zh) * 2013-07-25 2015-08-26 上海交通大学 基于壳聚糖的两亲性嵌段共聚物及其合成方法
CN104031268B (zh) * 2014-05-09 2017-01-11 上海交通大学 聚乙烯亚胺三嵌段共聚物及其在基因载体中的用途
CN106366264B (zh) * 2016-09-30 2018-12-11 东莞理工学院 一种三嵌段共聚物以及其调控方法
CN106967211B (zh) * 2017-04-05 2019-05-17 南京大学 紫杉醇-聚乳酸-紫杉醇共聚物及其制备方法与应用
US20190054527A1 (en) * 2017-08-18 2019-02-21 General Electric Company Thermoplastic binders for use in binder jetting additive manufacturing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165810A1 (en) * 2004-12-28 2006-07-27 The Trustees Of The University Of Pennsylvania Controlled release from block co-polymer worm micelles
CN102153761B (zh) * 2011-01-21 2013-06-19 上海交通大学 用于合成两亲性嵌段共聚物的模块化合物及其制备方法
CN102558535B (zh) * 2011-12-14 2014-01-15 上海交通大学 通过分子胶连接的两亲性嵌段共聚物及其合成方法与应用
CN103059311B (zh) * 2012-12-21 2014-11-19 上海交通大学 基于分子胶的aba型两亲性三嵌段共聚物及其用途

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WO2014094539A1 (fr) 2014-06-26
CN103059311A (zh) 2013-04-24

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