CN103055208A - Spleen invigorating and appetite promoting tablet and its making method - Google Patents
Spleen invigorating and appetite promoting tablet and its making method Download PDFInfo
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Abstract
The invention relates to a spleen invigorating and appetite promoting tablet. The spleen invigorating and appetite promoting tablet is prepared through tabletting a soft material and a flow aid; the soft material is prepared through using 100-160 parts by weight of a raw material concentrate, 10-20 parts by weight of haw powder, 9-11 parts by weight of an auxiliary material zinc gluconate and 25-35 parts by weight of sucrose; the flow aid is magnesium stearate, and the addition mass of magnesium stearate accounts for 0.3-0.7% of the total mass of the raw material concentrate, the haw powder, zinc gluconate and the sucrose powder; and the raw drugs of the concentrate comprise 55-85 parts by weight of haw, 8-12 parts by weight of malt, 9-11 parts by weight of Radish Seed, 4-6 parts by weight of white hyacinth bean and 3-7 parts by weight of dried orange peel. The tablet has the efficacies of food digestion, stomach strengthening, qi rectifying, spleen invigorating and appetite promoting, can effectively alleviate and treat symptoms comprising gastral cavity fullness, food indigestion, spleen-stomach deficiency, appetite loss and the like, and can also prevent the appearance of anorexia.
Description
Technical field
The invention belongs to field of traditional Chinese, relate generally to a kind of tablet and preparation method thereof, specifically a kind of spleen benefiting and stimulating the appetite sheet and preparation method thereof.
Background technology
In daily life, many people are arranged because overwork, the excessive anorexia, weakness of the spleen and stomach, breast flatulence of causing of stress be full, even long-term anorexia causes the health lassitude and weak, cisco unity malfunction; Also have a lot of children, because father and mother spoil, edible various snacks, sweets cause taste discomfort, disorder of function of stomach, anorexia etc., cause child's asthenic body how sick, unhealthful growth.In addition, people are when the treatment various diseases, no matter be adult or child, take various medicines after, be easy to cause taste discomfort, distension and fullness of the chest and abdomen, anorexia etc., have a strong impact on healthy, particularly the old people because can not get the conditioning on the diet after ill, causes prolonged constipation, the symptoms such as abdominal part distension, taste discomfort cause the health extremely feeble.Therefore, in time take the medicine of some spleen benefiting and stimulating the appetite, promote taste healthy, can alleviate the patient suffering, health can obtain rehabilitation early.
Summary of the invention
The present invention provides a kind of spleen benefiting and stimulating the appetite sheet for solving the problems of the technologies described above, and this spleen benefiting and stimulating the appetite sheet has the effect of promoting digestion and invigorating the stomach, regulating qi-flowing for strengthening spleen, can be effective to the symptoms such as gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of spleen benefiting and stimulating the appetite sheet, and described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by raw material concentrated solution 100-160 part, Fructus Crataegi powder 10-20 part and adjuvant zinc gluconate 9-11 part, cane sugar powder 25-35 part according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is the 0.3%-0.7% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount;
The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: Fructus Crataegi 55-85 part, Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part and Pericarpium Citri Reticulatae 3-7 part.
Described spleen benefiting and stimulating the appetite sheet may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 5-9h under 40-80 ℃ of condition, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 15-40min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part, Pericarpium Citri Reticulatae 3-7 part and the Fructus Crataegi 55-85 part of getting process pre-treatment in the step 1 place in the extraction pot, add water 100-150 part at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution 100-160 part of getting in the step 2 places the efficient asymmetric mixer of V-type, then add zinc gluconate 9-11 part, cane sugar powder 25-35 part and process step 3 and process the ultra micro Fructus Crataegi fine powder 10-20 part that obtains, be to mix 4-6 time under the condition of 28r/min at speed of agitator, each 7-9min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material, for subsequent use;
Step 5, tabletting, packing: adding quality in the soft material that makes to step 4 is the magnesium stearate of the 0.3%-0.7% of soft material total amount, uses the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
Wherein, Fructus Crataegi: sour, sweet, tepor, return spleen, stomach, Liver Channel, have the function of promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, convergence dysentery relieving, to the long-pending phlegm retention of meat, feeling of fullness acid regurgitation,, children's's breast food stagnates etc. all effective in cure;
Fructus Hordei Germinatus: sweet, flat, return spleen, stomach warp, have spleen benefiting and stimulating the appetite, move back the effect of newborn relieving distension, be used for the symptoms such as food stagnation does not disappear, abdominal distention, insufficiency of the spleen lack of appetite;
Semen Raphani: hot, sweet, flat, return lung, spleen, stomach warp, having helps digestion removes function swollen, lowering the adverse-rising QI to resolve phlegm, is used for retention of food and drink, abdominal distention, stagnant dysentery etc.;
Semen Lablab Album: sweet, tepor, return spleen, stomach warp, have the symptoms such as weakness of the spleen and stomach, inappetence, large loose stool are write, heat-damp in summer vomiting and diarrhoea, abdominal distention uncomfortable in chest;
Pericarpium Citri Reticulatae: bitter, hot, warm, return lung, spleen channel, have the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, be used for distension and fullness of the chest and abdomen, lack of appetite and vomiting, cough with copious phlegm;
Zinc gluconate: white crystals or particulate powder can be used for the symptoms such as malnutrition, apositia, growth retardation;
Cane sugar powder: odorless, flavor are sweet, belong to nutrition class material, correctives, excipient;
Magnesium stearate: fluidizer.
Beneficial effect of the present invention:
In one, the prescription, the equal spleen of Fructus Crataegi, Fructus Hordei Germinatus, Semen Lablab Album and Semen Raphani, stomach warp, effect with warming middle-JIAO nourishing the stomach, strengthening the spleen to promote digestion, and focus on warming the spleen, use mutually combines, treatment to symptoms such as weakness of the spleen and stomach, distension and fullness of the chest and abdomen, food stagnation do not disappear is evident in efficacy, adds Pericarpium Citri Reticulatae and helps regulating qi-flowing for strengthening spleen, the treatment distension and fullness of the chest and abdomen; Add zinc gluconate in the Chinese medicine, the Chinese and Western combination can not only replenish the zinc that needed by human body is wanted, and also can improve the human body sense of taste, strengthens medicine to the promotion of human body appetite, and can strengthen human body to the absorption of medicine; More than the mutual compatibility of several medical materials, both made the present invention have the effect of promoting digestion and invigorating the stomach, regulating qi-flowing for strengthening spleen, appetite stimulator, can effectively alleviate and treat the symptoms such as gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence, also can prevent the generation of apositia.
They are two years old, Fructus Crataegi is as a kind of principal agent among the present invention, a part and Fructus Hordei Germinatus, Semen Lablab Album, Semen Raphani and Pericarpium Citri Reticulatae digestion obtain lixiviating solution, Fructus Crataegi and Fructus Hordei Germinatus in the lixiviating solution that obtains, Semen Lablab Album, Semen Raphani and Pericarpium Citri Reticulatae mutually combine, mutually promote, the warming middle-JIAO nourishing the stomach, the effect of strengthening the spleen to promote digestion is remarkable, another part obtains the Fructus Crataegi fine powder by pulverizing, mutually mix with lixiviating solution and adjuvant, promoting digestion and invigorating the stomach with Fructus Crataegi, activating blood circulation to dissipate blood stasis, the Function of convergence dysentery relieving arrives at utmost, again in conjunction with Fructus Hordei Germinatus in the lixiviating solution, Semen Lablab Album, the effect of Semen Raphani and Pericarpium Citri Reticulatae is alleviated the present invention and is treated the gastral cavilty distension, food stagnation does not disappear, weakness of the spleen and stomach, the effect of the symptoms such as inappetence is remarkable.
Three, among the present invention Fructus Crataegi powder is carried out micronizing, fully abolish cell wall, effective ingredient is fully come out, then be combined with other compositions, can improve utilization rate biology of Chinese crude drug, promote drug effect.
Four, preparation technology of the present invention is simple, efficient, and tablet stores simply, carries and take, and is suitable for applying.
The specific embodiment
A kind of spleen benefiting and stimulating the appetite sheet, described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by raw material concentrated solution 100-160 part, Fructus Crataegi powder 10-20 part and adjuvant zinc gluconate 9-11 part, cane sugar powder 25-35 part according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is the 0.3%-0.7% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount;
The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: Fructus Crataegi 55-85 part, Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part and Pericarpium Citri Reticulatae 3-7 part.
Described spleen benefiting and stimulating the appetite sheet may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 5-9h under 40-80 ℃ of condition, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 15-40min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part, Pericarpium Citri Reticulatae 3-7 part and the Fructus Crataegi 55-85 part of getting process pre-treatment in the step 1 place in the extraction pot, add water 100-150 part at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution 100-160 part of getting in the step 2 places the efficient asymmetric mixer of V-type, then add zinc gluconate 9-11 part, cane sugar powder 25-35 part and process step 3 and process the ultra micro Fructus Crataegi fine powder 10-20 part that obtains, be to mix 4-6 time under the condition of 28r/min at speed of agitator, each 7-9min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material, for subsequent use;
Step 5, tabletting, packing: adding quality in the soft material that makes to step 4 is the magnesium stearate of the 0.3%-0.7% of soft material total amount, uses the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
The present invention will be further described below in conjunction with specific embodiment:
Embodiment 1:
A kind of spleen benefiting and stimulating the appetite sheet, described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by 25 parts of 160 parts of raw material concentrated solutions, 10 parts of Fructus Crataegi powder and 9 parts of adjuvant zinc gluconate, cane sugar powders according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is 0.3% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount; The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: 3 parts of 85 parts of Fructus Crataegis, 8 parts in Fructus Hordei Germinatus, 9 parts of Semen Raphanis, 4 parts of Semen Lablab Albums and Pericarpium Citri Reticulataes.
The preparation method of described spleen benefiting and stimulating the appetite sheet may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 9h under 40 ℃ of conditions, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 15min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: get that Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album, Pericarpium Citri Reticulatae and the Fructus Crataegi through pre-treatment places in the extraction pot in the step 1 of above-mentioned formula ratio, add 100 parts in water at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution of getting in the step 2 of formula ratio places the efficient asymmetric mixer of V-type, then add zinc gluconate, the cane sugar powder of formula ratio and the ultra micro Fructus Crataegi fine powder that processing obtains through step 3, be to mix 4 times under the condition of 28r/min at speed of agitator, each 7min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material;
Step 5, tabletting, packing: add the magnesium stearate of formula ratio in the soft material that makes to step 4, use the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
Embodiment 2:
A kind of spleen benefiting and stimulating the appetite sheet, described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by 35 parts of 100 parts of raw material concentrated solutions, 20 parts of Fructus Crataegi powder and 11 parts of adjuvant zinc gluconate, cane sugar powders according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is 0.7% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount; The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: 7 parts of 55 parts of Fructus Crataegis, 12 parts in Fructus Hordei Germinatus, 11 parts of Semen Raphanis, 6 parts of Semen Lablab Albums and Pericarpium Citri Reticulataes.
The preparation method of described spleen benefiting and stimulating the appetite sheet may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 5h under 80 ℃ of conditions, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 40min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: get that Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album, Pericarpium Citri Reticulatae and the Fructus Crataegi through pre-treatment places in the extraction pot in the step 1 of above-mentioned formula ratio, add 150 parts in water at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution of getting in the step 2 of formula ratio places the efficient asymmetric mixer of V-type, then add zinc gluconate, the cane sugar powder of formula ratio and the ultra micro Fructus Crataegi fine powder that processing obtains through step 3, be to mix 6 times under the condition of 28r/min at speed of agitator, each 9min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material;
Step 5, tabletting, packing: add the magnesium stearate of formula ratio in the soft material that makes to step 4, use the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
Embodiment 3:
A kind of spleen benefiting and stimulating the appetite sheet, described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by 30 parts of 130 parts of raw material concentrated solutions, 15 parts of Fructus Crataegi powder and 10 parts of adjuvant zinc gluconate, cane sugar powders according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is 0.5% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount; The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: 5 parts of 70 parts of Fructus Crataegis, 10 parts in Fructus Hordei Germinatus, 10 parts of Semen Raphanis, 5 parts of Semen Lablab Albums and Pericarpium Citri Reticulataes.
The preparation method of described spleen benefiting and stimulating the appetite sheet may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 7h under 60 ℃ of conditions, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 27.5min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: get that Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album, Pericarpium Citri Reticulatae and the Fructus Crataegi through pre-treatment places in the extraction pot in the step 1 of above-mentioned formula ratio, add 125 parts in water at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution of getting in the step 2 of above-mentioned formula ratio places the efficient asymmetric mixer of V-type, then add zinc gluconate, the cane sugar powder of formula ratio and the ultra micro Fructus Crataegi fine powder that processing obtains through step 3, be to mix 5 times under the condition of 28r/min at speed of agitator, each 8min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material;
Step 5, tabletting, packing: add the magnesium stearate of formula ratio in the soft material that makes to step 4, use the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
Clinical testing data
Prove that by the clinical trial to the multidigit patient a kind of spleen benefiting and stimulating the appetite sheet provided by the invention has the effect of promoting digestion and invigorating the stomach, regulating qi-flowing for strengthening spleen, appetite stimulator
In the clinical trial, choose at random 128 routine patients, symptom is that gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence etc.
Administrated method: oral spleen benefiting and stimulating the appetite sheet, 3 times on the one, one time 4, every 0.5g, children's is cut down according to the circumstance, 5 days is a course for the treatment of.
Criterion of therapeutical effect:
Produce effects: the symptoms such as gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence disappear substantially;
Effectively: the sx↓s such as gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence;
Invalid: above symptom is showed no improvement.
The result shows: after medication course for the treatment of, in 128 routine patients with gastric disease, have 92 routine patients' gastral cavilty distension, food stagnation not disappear, the symptoms such as weakness of the spleen and stomach, inappetence disappear substantially, are produce effects; After using again a course for the treatment of, have 35 routine patients' gastral cavilty distension, food stagnation not disappear, the sx↓ such as weakness of the spleen and stomach, inappetence, for effectively; The above symptom of all the other 1 routine patients does not all alleviate, and it is invalid to be considered as.
Result of the test shows: a kind of spleen benefiting and stimulating the appetite sheet, its obvious effective rate are 71.9%, effective percentage 27.3%, and inefficiency is 0.8%, total effective rate is 99.2%.Illustrate that this strengthening the spleen to promote digestion sheet has the effect of promoting digestion and invigorating the stomach, regulating qi-flowing for strengthening spleen, appetite stimulator, can effectively treat and alleviate the symptoms such as gastral cavilty distension, food stagnation do not disappear, weakness of the spleen and stomach, inappetence.
Model case
Case 1: Chen, man, 10 years old, symptom is that food stagnation does not disappear, weakness of the spleen and stomach, inappetence, adopts medicine provided by the invention to treat, every day 3 times, after 5 days, food stagnation does not disappear, the symptom complete obiteration of weakness of the spleen and stomach, inappetence, and it is effective to take this spleen benefiting and stimulating the appetite sheet.
Case 2: Wang, woman, 26 years old, symptom is gastral cavilty distension, weakness of the spleen and stomach, inappetence, adopts medicine provided by the invention to treat, every day 3 times, after 1 course for the treatment of, the transference cure of gastral cavilty distension, weakness of the spleen and stomach, inappetence, it is effective to take this spleen benefiting and stimulating the appetite sheet.
Case 3: Liu, the woman, 44 years old, symptom was that gastral cavilty distension, food stagnation do not disappear, and adopts medicine provided by the invention to treat, every day 3 times, after 2 days, the transference cure that gastral cavilty distension, food stagnation do not disappear, it is effective to take this spleen benefiting and stimulating the appetite sheet.
Case 4: Guo, the man, 68 years old, symptom was gastral cavilty distension, weakness of the spleen and stomach, adopted medicine provided by the invention to treat, every day 3 times, after 5 days, the transference cure of gastral cavilty distension, weakness of the spleen and stomach, it is effective to take this spleen benefiting and stimulating the appetite sheet.
Claims (2)
1. spleen benefiting and stimulating the appetite sheet, it is characterized in that: described spleen benefiting and stimulating the appetite sheet is made by soft material and fluidizer tabletting; Described soft material is made by raw material concentrated solution 100-160 part, Fructus Crataegi powder 10-20 part and adjuvant zinc gluconate 9-11 part, cane sugar powder 25-35 part according to parts by weight; Described fluidizer is magnesium stearate, and the adding quality of magnesium stearate is the 0.3%-0.7% of raw material concentrated solution, Fructus Crataegi powder, zinc gluconate and cane sugar powder total amount;
The crude drug of described concentrated solution is comprised of Fructus Crataegi, Fructus Hordei Germinatus, Semen Raphani, Semen Lablab Album and Pericarpium Citri Reticulatae, and the parts by weight of each medical material are: Fructus Crataegi 55-85 part, Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part and Pericarpium Citri Reticulatae 3-7 part.
2. the preparation method of a kind of spleen benefiting and stimulating the appetite sheet as claimed in claim 1 is characterized in that: may further comprise the steps:
Step 1, pre-treatment: get raw material Fructus Hordei Germinatus, Pericarpium Citri Reticulatae and Semen Lablab Album, choose respectively decontamination, wash respectively again, dry, for subsequent use; Get the raw material Fructus Crataegi, choose enucleation behind the decontamination, then clean with clear water, place thermostatic drying chamber dry 5-9h under 40-80 ℃ of condition, for subsequent use; Get the raw material Semen Raphani, wash after choosing decontamination, dry, then place in the heat pot, fry 15-40min with slow fire, heave and cracker is arranged to little, take out, cooling, smash to pieces, for subsequent use;
Step 2, lixiviate: Fructus Hordei Germinatus 8-12 part, Semen Raphani 9-11 part, Semen Lablab Album 4-6 part, Pericarpium Citri Reticulatae 3-7 part and the Fructus Crataegi 55-85 part of getting process pre-treatment in the step 1 place in the extraction pot, add water 100-150 part at every turn, decoct 2 times, each 2h, collecting decoction also filters, and filtrate places leaves standstill 12h in the settling tank, gets that relative density is 1.25 under supernatant concentration to the 90 ℃ condition, get concentrated solution, for subsequent use;
Step 3, pulverizing: the residue Fructus Crataegi of the step 1 of learning from else's experience pre-treatment, pulverize with Chinese medicine grinder, cross 100 mesh sieves, make the Fructus Crataegi fine powder, place baking oven under 100 ℃ of conditions, to dry 2h, take out, using ball mill that the Fructus Crataegi fine powder is carried out micronizing, is that 340 r/min, ratio of grinding media to material are under 8 the condition at rotating speed, pulverizes 1.5 h, obtain the Fructus Crataegi powder of micronizing, for subsequent use;
Step 4, mixing, granulation: the concentrated solution 100-160 part of getting in the step 2 places the efficient asymmetric mixer of V-type, then add zinc gluconate 9-11 part, cane sugar powder 25-35 part and process step 3 and process the ultra micro Fructus Crataegi fine powder 10-20 part that obtains, be to mix 4-6 time under the condition of 28r/min at speed of agitator, each 7-9min, behind the mix homogeneously, cross 14 mesh sieves and granulate, cross 16 mesh sieve granulate after the oven dry, make soft material, for subsequent use;
Step 5, tabletting, packing: adding quality in the soft material that makes to step 4 is the magnesium stearate of the 0.3%-0.7% of soft material total amount, uses the tablet machine tabletting behind the mix homogeneously, then plastic-aluminum packing or bottled, and with the C of 10MeV
60C
0Radiation gamma namely makes this spleen benefiting and stimulating the appetite sheet after the radiation sterilization.
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