CN106466446A - The preparation technology of selenium enriched Spirulina metformin - Google Patents
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of preparation technology of selenium enriched Spirulina metformin.A, select spirulina 50%, Semen Glyciness 5%, Semen sojae atricolor 6%, Semen Phaseoli 6%, Rhizoma Dioscoreae 10%, Radix Puerariae 6%, Poria 5%, Radix Trichosanthis 12% to be substantially square, wherein spirulina, Rhizoma Dioscoreae, Poria, Radix Puerariae, Radix Trichosanthis, break into coarse powder and front beans mixing for standby use；B, select Fructus Hordei Germinatus 30%, Fructus Lycii 20%, Stigma Maydis 30%, Radix Ophiopogonis 20%, decoct 30min, filtered juice, standby；C, the warm water mixing after uniform for the raw material stirring in a step, putting into liquid medicine in 5 times of b step gained and 5 times, soak at room temperature 8h, after bean or pea swelling, with beater, broken into screened stock, self-skimming, filtered out the more high mixing juice of concentration standby；D and then pour gained juice into is heated in jacketed pan boiling, and is changed to 60 DEG C and is concentrated into thick paste, puts to cooling, adds 10 times about crystal maltitols, Fragrance qs, mix homogeneously, is dried, pelletize, tabletting, obtains final product.
Description
Technical field
The present invention relates to a kind of preparation technology of selenium enriched Spirulina metformin.
Background technology
Diabetes patient, post-prandial glycemia raises, and is a worried problem, as long as someone confirms to drink one glass of bean milk after the meal, blood glucose will be decreased obviously.It was verified that bean milk is drunk after the meal really being beneficial to diabetes patient.But drink bean milk and inconvenience is it is impossible to meal meal has glass bean milk waiting you.And the soy milk powder sold on market, it is not directed to diabetes patient's design, is added with milk powder and sucrose, diabetes patient can not eat at all, its formula purpose has not a particle of benefit to diabetes.It is true that utilizing this carrier of bean milk, adding some more useful composition such as spirulinas etc., studying a kind of blood sugar lowering solid bean milk prescription, mouthfeel is more preferably, better, better than simple bean milk, after-dinner blood sugar of diabetes patients is controlled and will more be of practical significance.
Content of the invention
The purpose of the present invention refers to a kind of preparation technology of selenium enriched Spirulina metformin
The object of the present invention is achieved like this：A, select spirulina 50%, Semen Glyciness 5%, Semen sojae atricolor 6%, Semen Phaseoli 6%, Rhizoma Dioscoreae 10%, Radix Puerariae 6%, Poria 5%, Radix Trichosanthis 12% be substantially square, wherein spirulina, Rhizoma Dioscoreae, Poria, Radix Puerariae, Radix Trichosanthis, break into coarse powder and front beans mixing for standby use；B, select Fructus Hordei Germinatus 30%, Fructus Lycii 20%, Stigma Maydis 30%, Radix Ophiopogonis 20%, plus five times of water, 90 DEG C, decoct 30min, filtered juice, secondary decoction, secondary filtered juice, secondary juice mixes, without concentration, standby；C, the warm water mixing after uniform for the raw material stirring in a step, putting into liquid medicine in 5 times of b step gained and 5 times, totally 10 times of water, soak at room temperature 8h, after bean or pea swelling, with beater, broken into screened stock, self-skimming, filtered out the more high mixing juice of concentration standby；D and then pour gained juice into is heated in jacketed pan boiling, and is changed to 60 DEG C and is concentrated into thick paste, puts to cooling, adds 10 times about crystal maltitols, Fragrance qs, mix homogeneously, is dried, pelletize, sieves, tabletting, and infrared ray sterilizes, and obtains final product.
The positive effect of the present invention is：Unique with material, innovation, do multiple beans of bean milk and amyloid medicine root block, spirulina are pulled an oar altogether, and soaked with blood-sugar lowering tcm drug water, make the slurry played contain more blood sugar lowering compositions.Semen Glyciness：Major ingredient, accounts for 50%,《Compendium of Materia Medica》Claim, wide lower gas, profit large intestine, disappear watery distension toxic swelling.Modern times stir-fry and eat Semen Glyciness and drink bean milk blood sugar lowering and have a lot of reports.Scholar's research is abroad had to confirm, bean milk has hypoglycemic activity, and diabeticss drink the beverage that Semen sojae atricolor is made daily, it is possible to reduce the usage amount of insulin, have 1/3 patient can no longer accept insulin therapy.This medical expert makees clinical observation to 600 diabeticss, drinks bean milk after the meal, can reduce blood sugar content.US Experts are it also holds that Semen sojae atricolor truly has obvious curative effects to treatment diabetes, it is possible to reduce the usage amount of insulin, Sichuan medical college made clinical observation, and each diabetes patient takes 120 grams and boils Semen Glyciness, and 3 times a day, 40 grams every time, it is used in conjunction one month, its blood glucose, glucose in urine can recover normal level.Its cardinal principle, relevant with the composition possibility such as soybean isoflavone, epinephrine.Semen sojae atricolor：Claim medicine bean, it is askew to control middle air port, pyretic toxicity attacks eye, body and face edema, and in abdomen, painful abdominal mass is hard, and water dysentery is more than, and man has blood in stool, all hematochezia, injured, falling down, and blood stasis are in abdomen.Dental pain, retention of placenta.Semen Phaseoli：Edema due to disorder of QI of harnessing the river is swollen, dysentery, perianal abscess hematochezia, dental pain, galactostasiss, front cellulitis maiden work, and rib cheek heat is swollen, erysipelas such as fire, frequent micturition, bed-wetting.Spirulina：Spirulina is a kind of thread algae of glaucous many cells, belongs to Cyanophyta nostocaceae, and in loose or closely well-regulated spiral rotation shape bending, shape such as clockwork feed, so gain the name.Nutritious spirulina enriches, and it is rich in multiple necessary vitamin and mineral, and pure natural pigment class material, such as chlorophyll, carotenoid, beta-carotene, phylloxanthin etc., and the physiological action such as actively plays antioxidation, builds up resistance.Therefore, the nutritive value of spirulina includes：Enhancing immunity, antioxidant and anti-aging, enhance metabolism, wound healing promoting, radioprotective, resisting fatigue, antibacterial anti-infection, antitumor, improve regard healthy, the effects such as improve gastric and duodenal ulcers, blood fat reducing, blood sugar lowering, improve anemia.Rhizoma Dioscoreae：There are spleen invigorating, lung benefiting, reinforce the kidney, the function of arresting seminal emission, for solving empty chronic diarrhea, cough due to deficiency of the lung, emission due to deficiency of the kidney, leukorrhagia, the disease such as frequent micturition.There are hypoglycemic activity, enhance immunity.Radix Puerariae：There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, the function of Shengyang Zhixie, have a headache for fever caused by exogenous pathogens, stiffness of the nape, thirsty, quench one's thirst, hematodiarrhoea, have loose bowels, hypertension neck pain, coronary heart disease etc..Poria：Strengthening spleen and middle warmer, mind tranquilizing and the heart calming, diuretic, eliminating dampness by diuresis, containing pachyman, pachymic acid, protein, lecithin etc., Semen Coiciss：Promoting diuresis to eliminate damp pathogen, spleen invigorating, eliminating impediment.Clearing away heat and discharging pus, for dysuria, edema, the inclined victor of damp, can eliminating dampness by diuresis, and can relaxing muscles and tendons arteries and veins.Radix Trichosanthis：For calentura, pathogenic heat impairment of body fluid, dry mouth and tougue, excessive thirst and diabetess；For cough caused by dryness expectorant after cough due to lung-heat is thick and hemoptysis disease, it is additionally operable to carbuncle swells sore, excessive noxious heat, disappears and flutter damage blood stasis.Fructus Hordei Germinatus：Help digestion circulation of qi promoting, spleen benefiting and stimulating the appetite, the function of moves back newborn dissipate-swelling.For dyspepsia, abdominal distention, spleen eating less, milk smoulders etc., it is possible to decrease blood glucose.Stigma Maydis：Diuresis, blood sugar lowering, someone is used as corn stigma tea treatment diabetes effect substantially, has removing toxic substances, expels the heat-evil, and suppressing the hyperactive liver blood pressure lowering is especially particularly suitable to each patients with type Ⅰ DM, middle and elderly diabetic Complicated with Hypertension.Fructus Lycii：Nourishing the liver and kidney, nourishing the liver item, with controlling deficiency of kidney essence, soreness of the waist and knees, deficiency of the liver and kindey, dizzy blurred vision, blurred vision, hemopoietic, blood sugar lowering.Crystal maltitol：For adjuvant, sweet and sugar-free.
Specific embodiment
Combined formulation describes embodiment and drug action mechanism in detail.
A, select spirulina 50%, Semen Glyciness 5%, Semen sojae atricolor 6%, Semen Phaseoli 6%, Rhizoma Dioscoreae 10%, Radix Puerariae 6%, Poria 5%, Radix Trichosanthis 12% be substantially square, wherein spirulina, Rhizoma Dioscoreae, Poria, Radix Puerariae, Radix Trichosanthis, break into coarse powder and front beans mixing for standby use；B, select Fructus Hordei Germinatus 30%, Fructus Lycii 20%, Stigma Maydis 30%, Radix Ophiopogonis 20%, plus five times of water, 90 DEG C, decoct 30min, filtered juice, secondary decoction, secondary filtered juice, secondary juice mixes, without concentration, standby；C, the warm water mixing after uniform for the raw material stirring in a step, putting into liquid medicine in 5 times of b step gained and 5 times, totally 10 times of water, soak at room temperature 8h, after bean or pea swelling, with beater, broken into screened stock, self-skimming, filtered out the more high mixing juice of concentration standby；D and then pour gained juice into is heated in jacketed pan boiling, and is changed to 60 DEG C and is concentrated into thick paste, puts to cooling, adds 10 times about crystal maltitols, Fragrance qs, mix homogeneously, is dried, pelletize, sieves, tabletting, and infrared ray sterilizes, and obtains final product.
Semen Glyciness：Major ingredient, accounts for 50%,《Compendium of Materia Medica》Claim, wide lower gas, profit large intestine, disappear watery distension toxic swelling.Modern times stir-fry and eat Semen Glyciness and drink bean milk blood sugar lowering and have a lot of reports.Scholar's research is abroad had to confirm, bean milk has hypoglycemic activity, and diabeticss drink the beverage that Semen sojae atricolor is made daily, it is possible to reduce the usage amount of insulin, have 1/3 patient can no longer accept insulin therapy.This medical expert makees clinical observation to 600 diabeticss, drinks bean milk after the meal, can reduce blood sugar content.US Experts are it also holds that Semen sojae atricolor truly has obvious curative effects to treatment diabetes, it is possible to reduce the usage amount of insulin, Sichuan medical college made clinical observation, and each diabetes patient takes 120 grams and boils Semen Glyciness, and 3 times a day, 40 grams every time, it is used in conjunction one month, its blood glucose, glucose in urine can recover normal level.Its cardinal principle, relevant with the composition possibility such as soybean isoflavone, epinephrine.
Semen sojae atricolor：Claim medicine bean, it is askew to control middle air port, pyretic toxicity attacks eye, body and face edema, and in abdomen, painful abdominal mass is hard, and water dysentery is more than, and man has blood in stool, all hematochezia, injured, falling down, and blood stasis are in abdomen.Dental pain, retention of placenta.Testa sojae atricolor is raw to be used, and controls variola corneal nebula.
Semen Phaseoli：Edema due to disorder of QI of harnessing the river is swollen, dysentery, perianal abscess hematochezia, dental pain, galactostasiss, front cellulitis maiden work, and rib cheek heat is swollen, erysipelas such as fire, frequent micturition, bed-wetting.Semen Phaseoli heat content is low, higher containing dietary cellulose, and rich in vitamin E, and potassium, magnesium, phosphorus, zinc, selenium isoreactivity composition, its K factor（Potassium/sodium ratio）>3po, is typical high potassium food, has blood sugar lowering, lowering blood pressure and blood fat effect.Semen Phaseoli is the preferable blood sugar lowering food of diabeticss.Often eat Semen Phaseoli food and not only can reduce blood glucose, also obesity, hyperlipemia are merged to diabetes, hypertension has preventive and therapeutic effect.Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》Middle commentary Semen Phaseoli claims that " this medicine controls all cellulitis sore scabies and red swollen, bad-looking good and evil, adjusts with water and removes it, no unhealed." this prompting, centering Senile Advanced diabeticss merging pulmonary infection and skin scabies, carbuncle, furuncle person has Clinical significance of MG.
Rhizoma Dioscoreae：Sweet in the mouth, mild-natured, there are spleen invigorating, lung benefiting, reinforce the kidney, the function of arresting seminal emission, for solving empty chronic diarrhea, cough due to deficiency of the lung, emission due to deficiency of the kidney, leukorrhagia, the disease such as frequent micturition.There are hypoglycemic activity, enhance immunity.
Radix Puerariae：There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, the function of Shengyang Zhixie, have a headache for fever caused by exogenous pathogens, stiffness of the nape, thirsty, quench one's thirst, hematodiarrhoea, have loose bowels, hypertension neck pain, coronary heart disease etc..It contains Radix Puerariae flavone, puerarin, soybean isoflavone etc., and the metabolism to the cardiac muscle of infarction has good action.
Poria：Strengthening spleen and middle warmer, mind tranquilizing and the heart calming, diuretic, eliminating dampness by diuresis, containing pachyman, pachymic acid, protein, lecithin etc., the discharge of the electrolyte such as sodium, potassium, chlorine can be promoted, immunity, antitumor, liver protection can be improved, to cardiovascular, diabetes are all beneficial.
Spirulina：Spirulina is a kind of thread algae of glaucous many cells, belongs to Cyanophyta nostocaceae, and in loose or closely well-regulated spiral rotation shape bending, shape such as clockwork feed, so gain the name.Nutritious spirulina enriches, and it is rich in multiple necessary vitamin and mineral, and pure natural pigment class material, such as chlorophyll, carotenoid, beta-carotene, phylloxanthin etc., and the physiological action such as actively plays antioxidation, builds up resistance.Therefore, the nutritive value of spirulina includes：Enhancing immunity, antioxidant and anti-aging, enhance metabolism, wound healing promoting, radioprotective, resisting fatigue, antibacterial anti-infection, antitumor, improve regard healthy, the effects such as improve gastric and duodenal ulcers, blood fat reducing, blood sugar lowering, improve anemia.
Radix Trichosanthis：Hardship, micro-sweet, cold in nature, for calentura, pathogenic heat impairment of body fluid, dry mouth and tougue, excessive thirst and diabetess；For cough caused by dryness expectorant after cough due to lung-heat is thick and hemoptysis disease, it is additionally operable to carbuncle swells sore, excessive noxious heat, disappears and flutter damage blood stasis.
Fructus Hordei Germinatus：Help digestion circulation of qi promoting, spleen benefiting and stimulating the appetite, the function of moves back newborn dissipate-swelling.For dyspepsia, abdominal distention, spleen eating less, milk smoulders etc..Fructus Hordei Germinatus contain abundant vitamin D, E, phospholipid etc., it is possible to decrease blood glucose.
Stigma Maydis：Cool in nature, in place of popcorn pollination, nutrition, pharmaceutical value are high, diuresis, blood sugar lowering, and someone is used as corn stigma tea treatment diabetes effect substantially, has removing toxic substances, expels the heat-evil, and suppressing the hyperactive liver blood pressure lowering is especially particularly suitable to each patients with type Ⅰ DM, middle and elderly diabetic Complicated with Hypertension.
Fructus Lycii：Nourishing the liver and kidney, nourishing the liver item, with controlling deficiency of kidney essence, soreness of the waist and knees, deficiency of the liver and kindey, dizzy blurred vision, blurred vision, hemopoietic, blood sugar lowering.
Crystal maltitol：For adjuvant, sweet and sugar-free.
Claims (1)
1. a kind of preparation technology of selenium enriched Spirulina metformin, its method is as follows：A, select spirulina 50%, Semen Glyciness 5%, Semen sojae atricolor 6%, Semen Phaseoli 6%, Rhizoma Dioscoreae 10%, Radix Puerariae 6%, Poria 5%, Radix Trichosanthis 12% be substantially square, wherein spirulina, Rhizoma Dioscoreae, Poria, Radix Puerariae, Radix Trichosanthis, break into coarse powder and front beans mixing for standby use；B, select Fructus Hordei Germinatus 30%, Fructus Lycii 20%, Stigma Maydis 30%, Radix Ophiopogonis 20%, plus five times of water, 90 DEG C, decoct 30min, filtered juice, secondary decoction, secondary filtered juice, secondary juice mixes, without concentration, standby；C, the warm water mixing after uniform for the raw material stirring in a step, putting into liquid medicine in 5 times of b step gained and 5 times, totally 10 times of water, soak at room temperature 8h, after bean or pea swelling, with beater, broken into screened stock, self-skimming, filtered out the more high mixing juice of concentration standby；D and then pour gained juice into is heated in jacketed pan boiling, and is changed to 60 DEG C and is concentrated into thick paste, puts to cooling, adds 10 times about crystal maltitols, Fragrance qs, mix homogeneously, is dried, pelletize, sieves, tabletting, and infrared ray sterilizes, and obtains final product.
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| CN112843150A (en) * | 2020-01-08 | 2021-05-28 | 中国科学院生物物理研究所 | Composition containing wolfberry extract and preparation method and application method thereof |
| US11135260B2 (en) * | 2020-01-08 | 2021-10-05 | Institute Of Biophysics, Chinese Academy Of Sciences | Lycium barbarum extracts, resulting compositions, methods of making and methods of using the same |
| CN112843150B (en) * | 2020-01-08 | 2022-03-15 | 中国科学院生物物理研究所 | Composition containing wolfberry extract and preparation method and application method thereof |
| US11529385B2 (en) | 2020-01-08 | 2022-12-20 | Institute Of Biophysics, Chinese Academy Of Sciences | Lycium barbarum extracts, resulting compositions, methods of making and methods of using the same |
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