CN103055029A - Traditional Chinese medicine composition for treating systemic lupus erythematosus and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating systemic lupus erythematosus and preparation method thereof Download PDFInfo
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- CN103055029A CN103055029A CN201210595149XA CN201210595149A CN103055029A CN 103055029 A CN103055029 A CN 103055029A CN 201210595149X A CN201210595149X A CN 201210595149XA CN 201210595149 A CN201210595149 A CN 201210595149A CN 103055029 A CN103055029 A CN 103055029A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating systemic lupus erythematosus. The composition of the traditional Chinese medicine comprises scutellaria baicalensis, coptis chinensis, pericarpium citri reticulatae, liquorice, radix scrophulariae, radix bupleuri, platycodon grandiflorum, fructus forsythiae, isatis roots, puffballs, burdock, mint, stiff silkworm, cimicifugae foetidae, caulis Spatholobi, cortex dictamni, and perilla nankinensis and/or an acceptable carrier in pharmacy. The invention further discloses a preparation method of the composition of the traditional Chinese medicine. The composition of the traditional Chinese medicine has the functions of clearing away heat and toxic materials, invigorating the circulation of blood, dispelling turbidity and the like, is used for treating systemic lupus erythematosus clinically, and is good in curative effect, low in recurrence rate and free from toxic and side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically, relates to Chinese medicine composition of a kind of systemic lupus erythematosus and preparation method thereof.
Background technology
Systemic lupus erythematosus (sle) (systemic lupus erythematosus, SLE) is the autoimmune mediation, the Diffuse Connective Tissue Disease take immune inflammation as outstanding behaviours.The SLE complicated clinical manifestation is various.Majority is the concealment onset, 1~2 system is only involved in beginning, show slight arthritis, erythra, latent nephritis, thrombocytopenic purpura etc., the some patients were long-term stability is in sub-clinical state or light-duty lupus, some patients were can by the light-duty serious symptom lupus that becomes suddenly, more then be damaged by the light-duty multisystem that engenders; Just involve a plurality of systems when also having some patients to fall ill, even show as the lupus crisis.
The whole world prevalence be about 30~50,/10 ten thousand people, the prevalence of China is about 70,/10 ten thousand people, among the women then up to 1,15/,100,000 people.SLE is apt to occur in young women, and onset peak is 15~45 years old, and men and women's morbidity ratio is about 1: 9.The men and women's of childhood and senile SLE ratio is about 1: 2.
At present, doctor trained in Western medicine adopts the medicines such as hormone, immunosuppressant more to the treatment of systemic lupus erythematosus (sle), but its side effect is large, and easily recurrence.
Systemic lupus erythematosus (sle) is belonged to respectively " YIN YANG toxin syndrome ", " butterfly spot ", " general arthralgia ", " solar dermatitis ", " itching eruption due to wind-heat in blood ", " maculae caused by violent heat pathogen ", " kidney pathogenic wind toxic " etc. according to the clinical symptoms difference in the classic of TCM, the inventor adopts strengthening vital QI to eliminate pathogenic factors, method for the treatment of is heat-clearing and toxic substances removing, and invigorating blood circulation, it is turbid to let out.Its therapeutic effect is good, and relapse rate is low, has no side effect.
Summary of the invention
The Chinese medicine composition that the purpose of this invention is to provide a kind of systemic lupus erythematosus.
The present invention also aims to provide a kind of preparation method of Chinese medicine composition of systemic lupus erythematosus.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition of systemic lupus erythematosus, be to be made by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is to be made by weight by following raw material:
Effective ingredient preferably by following raw materials according by making by weight:
The present invention also provides the preparation method of this Chinese medicine composition, comprises the steps:
(1) getting respectively Radix Scutellariae, Rhizoma Coptidis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Radix Scrophulariae, Radix Bupleuri, Radix Platycodonis, Fructus Forsythiae, Radix Isatidis, Lasiosphaera Seu Calvatia, Fructus Arctii, Herba Menthae, Bombyx Batryticatus, Rhizoma Cimicifugae, Caulis Spatholobi, Cortex Dictamni, Folium Perillae by proportioning decocts with water 2 times, 2 hours for the first time, 1.5 hours for the second time, filter merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.30 (80 ℃) that concentrating under reduced pressure becomes relative density, drying, be ground into fine powder, with pharmaceutically acceptable carrier granulation, capsule, tablet.
(2) Chinese medicine composition of the present invention can with pharmaceutically acceptable carrier, such as filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Use by granule, capsule, tablet Oral administration.
Chinese medicine composition of the present invention has heat-clearing and toxic substances removing, invigorates blood circulation and lets out the turbid effect of Denging, is used for the treatment of clinically systemic lupus erythematosus (sle).
The specific embodiment
Following examples are used for explanation the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: Chinese medicinal composition granules of the present invention
Get Radix Scutellariae 750g, Rhizoma Coptidis 750g, Pericarpium Citri Reticulatae 300g, Radix Glycyrrhizae 300g, Radix Scrophulariae 300g, Radix Bupleuri 300g, Radix Platycodonis 300g, Fructus Forsythiae 150g, Radix Isatidis 150g, Lasiosphaera Seu Calvatia 150g, Fructus Arctii 150g, Herba Menthae 150g, Bombyx Batryticatus 100g, Rhizoma Cimicifugae 100g, Caulis Spatholobi 750g, Cortex Dictamni 300g, Folium Perillae 300g decocts with water 2 times, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.30 (80 ℃) that concentrating under reduced pressure becomes relative density, drying, be ground into fine powder, add lactose 300g, DEXTRIN 0g, mixing sieves, with 75% ethanol wet granulation, drying, pack and get final product.
Embodiment 2: Chinese medicinal composition capsules agent of the present invention
Get Radix Scutellariae 750g, Rhizoma Coptidis 750g, Pericarpium Citri Reticulatae 300g, Radix Glycyrrhizae 300g, Radix Scrophulariae 300g, Radix Bupleuri 300g, Radix Platycodonis 300g, Fructus Forsythiae 150g, Radix Isatidis 150g, Lasiosphaera Seu Calvatia 150g, Fructus Arctii 150g, Herba Menthae 150g, Bombyx Batryticatus 100g, Rhizoma Cimicifugae 100g, Caulis Spatholobi 750g, Cortex Dictamni 300g, Folium Perillae 300g decocts with water 2 times, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.30 (80 ℃) that concentrating under reduced pressure becomes relative density, drying is ground into fine powder, adds dextrin 350g, mixing is in the capsulae vacuus of packing into and get final product.
Embodiment 3: Chinese medicine composition tablet of the present invention
Get Radix Scutellariae 750g, Rhizoma Coptidis 750g, Pericarpium Citri Reticulatae 300g, Radix Glycyrrhizae 300g, Radix Scrophulariae 300g, Radix Bupleuri 300g, Radix Platycodonis 300g, Fructus Forsythiae 150g, Radix Isatidis 150g, Lasiosphaera Seu Calvatia 150g, Fructus Arctii 150g, Herba Menthae 150g, Bombyx Batryticatus 100g, Rhizoma Cimicifugae 100g, Caulis Spatholobi 750g, Cortex Dictamni 300g, Folium Perillae 300g decocts with water 2 times, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.30 (80 ℃) that concentrating under reduced pressure becomes relative density, drying, be ground into fine powder, add starch 250g, microcrystalline Cellulose 200g, mixing sieves, with 75% ethanol wet granulation, tabletting, coating and get final product.
Although, above with a general description of the specific embodiments the present invention having been done detailed description, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements all belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (4)
3. such as the arbitrary described Chinese medicine composition of right 1-2, it is characterized in that described Chinese medicine composition can be made into granule, capsule, tablet.
4. the preparation method such as the arbitrary described Chinese medicine composition of right 1-3 comprises the steps:
(1) getting respectively Radix Scutellariae, Rhizoma Coptidis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Radix Scrophulariae, Radix Bupleuri, Radix Platycodonis, Fructus Forsythiae, Radix Isatidis, Lasiosphaera Seu Calvatia, Fructus Arctii, Herba Menthae, Bombyx Batryticatus, Rhizoma Cimicifugae, Caulis Spatholobi, Cortex Dictamni, Folium Perillae by proportioning decocts with water 2 times, 2 hours for the first time, 1.5 hours for the second time, filter merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.30 (80 ℃) that concentrating under reduced pressure becomes relative density, drying, be ground into fine powder, with pharmaceutically acceptable carrier granulation, capsule, tablet.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104740404A (en) * | 2015-04-13 | 2015-07-01 | 杜卫卫 | Traditional Chinese medicine composition for treating lupus erythematosus |
CN105985403A (en) * | 2015-02-01 | 2016-10-05 | 复旦大学 | Fortisterol and use thereof in preparation of anticomplement drugs |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102370799A (en) * | 2010-08-19 | 2012-03-14 | 王雅欣 | Traditional Chinese medicine decoction for treating head erysipelas |
-
2012
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102370799A (en) * | 2010-08-19 | 2012-03-14 | 王雅欣 | Traditional Chinese medicine decoction for treating head erysipelas |
Non-Patent Citations (4)
Title |
---|
傅子健: "普济消毒饮治疗皮肤病经验", 《江西中医药》 * |
周瑞珍: "梁剑波老中医运用普济消毒饮经验介绍", 《新中医》 * |
周瑞珍等: "加味普济消毒饮合强的松治疗系统性红斑狼疮的临床观察", 《中国中西医结合肾病杂志》 * |
景瑛等: "《皮肤病性病临床诊治》", 31 January 2006, 科学技术文献出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105985403A (en) * | 2015-02-01 | 2016-10-05 | 复旦大学 | Fortisterol and use thereof in preparation of anticomplement drugs |
CN105985403B (en) * | 2015-02-01 | 2017-12-29 | 复旦大学 | A kind of sterol lactone and its purposes in anticomplement medicament is prepared |
CN104740404A (en) * | 2015-04-13 | 2015-07-01 | 杜卫卫 | Traditional Chinese medicine composition for treating lupus erythematosus |
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Application publication date: 20130424 |