CN103041375A - Marine biological hemorrhoidal anti-inflammatory repairing lotion and preparation method thereof - Google Patents
Marine biological hemorrhoidal anti-inflammatory repairing lotion and preparation method thereof Download PDFInfo
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- CN103041375A CN103041375A CN2012105463636A CN201210546363A CN103041375A CN 103041375 A CN103041375 A CN 103041375A CN 2012105463636 A CN2012105463636 A CN 2012105463636A CN 201210546363 A CN201210546363 A CN 201210546363A CN 103041375 A CN103041375 A CN 103041375A
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- antiinflammatory
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Abstract
The invention discloses a marine biological hemorrhoidal anti-inflammatory repairing lotion and a preparation method thereof. The repairing lotion comprises the following components by weight percent: 2.0-4.0% of carboxymethyl chitosan, 2.0-4.0% of algal polysaccharide, 6.0-8.0% of cecropin, 2.0-3.5% of mucopeptide-N-acetylmuramoylhydrolase, 1.0-2.5% of borneol, and 78-87% of water. According to the invention, the marine biological hemorrhoidal anti-inflammatory repairing lotion is efficient in the treatment of hemorrhoids, and fast in response, and further has the advantages of no pungent smell, convenience in use, and no stimulation to the skin.
Description
It is 201110423421.1 that the present invention requires application number, and the applying date is 2011.12.16, and denomination of invention is the priority of the Chinese invention patent of " epithelium and mucous membrane of rectum epithelial cell antiinflammatory maintenance liquid in marine organisms hemorrhoid and the anus ".
Technical field
The present invention relates to antiinflammatory maintenance liquid, relate in particular to a kind of marine organisms hemorrhoid antiinflammatory maintenance liquid and preparation method thereof.
Background technology
Hemorrhoid are human distinctive commonly encountered diseases, frequently-occurring disease.Show that according to relevant reconnaissance information the sickness rate of anorectal disease is 59.1%, hemorrhoid account for 87.25% in all anal and intestinal diseases, and sickness rate is high, badly influence people's healthy and Working Life.
Now hemorrhoid class ointment and the cleanout fluid on the market mostly is greatly Chinese medicine preparation, and patient's pain is alleviated and removed to ubiquity, the symptom effect such as swell, itch is slow; Carry and clean inconvenience; The problems such as penetrating odor is large.
Summary of the invention
An object of the present invention is to provide the fast marine organisms hemorrhoid antiinflammatory maintenance liquid of a kind of produce effects.
Another object of the present invention provides the preparation method of the fast marine organisms hemorrhoid antiinflammatory maintenance liquid of a kind of produce effects.
Marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.0 ~ 4.0%;
Sargassum polysaccharides 2.0 ~ 4.0%;
Cecropin 6.0 ~ 8.0%;
N-acetylmuramide lycanohydrlase 2.0 ~ 3.5%;
Borneolum Syntheticum 1.0 ~ 2.5%;
Water 78 ~ 87%.
The preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention comprises the steps:
Step S10: add carboxymethyl chitosan and the Sargassum polysaccharides of said ratio amount in 30 ~ 35 ℃ the water, mix to get mixed liquor A;
Step S20: add the cecropin of said ratio amount in the mixed liquor A, mix to get mixed liquid B;
Step S30: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of said ratio amount in the mixed liquid B, mix to get described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention has following beneficial effect:
1, made from pure-natural marine living-things preparation, nontoxic, tasteless, safe, to mucocutaneous non-stimulated, the sterilization bacteria-eliminating efficacy is remarkable, fast for treatment hemorrhoid antiinflammatory produce effects, after testing under the action time of 2-5min, can effectively kill escherichia coli, staphylococcus aureus, Candida albicans, sterilizing rate is 99.99%; Safety and stability is pollution-free.
2, use easy to carryly, antiinflammatory is quick, can alleviate and remove patient's pain, the symptom such as swell, itch, and makes the faster healing of focus.
3, directly act on anoderm cell and mucous membrane of rectum epithelial cell, effectively sterilization, antibacterial, antiinflammatory.Impel the focus cell to accelerate metabolism, shorten stable treatment maintenance and the maintenance of the course of disease.
4, marine bioactivity material and focus cell organically combine, accelerating the focus cell turnover regenerates, thereby remove abnormality cell and the new healthy cell of hypertrophy, useful and do not injure healthy cell to cell, namely to human body skin, anoderm and mucous membrane of rectum epithelium do not stimulate irritated side effect.
5, the occupation mode of colorless and odorless and safe and convenient can make the patient get timely medical treatment, maintain, with cleaning, and effectively finish the focus cell-targeting is repaired and maintenance, the focus cell is exhaled the old and inhale the new, accelerate metabolism, thereby recover and alleviate the symptom of patient's piles, reduce operative treatment and can accelerate the wound healing of hands postoperative patient, lay good treatment basic guarantee for stopping palindromia.
The preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention is because order by merging and the mixing condition of each material are comparatively reasonable, so that by each component mix homogeneously of preparation method marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention, good stability.
The specific embodiment
Embodiment 1
A kind of marine organisms hemorrhoid antiinflammatory maintenance liquid comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.0 ~ 4.0%;
Sargassum polysaccharides 2.0 ~ 4.0%;
Cecropin 6.0 ~ 8.0%;
N-acetylmuramide lycanohydrlase 2.0 ~ 3.5%;
Borneolum Syntheticum 1.0 ~ 2.5%;
Water 78 ~ 87%.
The marine organisms hemorrhoid antiinflammatory maintenance liquid of present embodiment has following beneficial effect:
1, made from pure-natural marine living-things preparation, nontoxic, tasteless, safe, to mucocutaneous non-stimulated, the sterilization bacteria-eliminating efficacy is remarkable, fast for treatment hemorrhoid antiinflammatory produce effects, after testing under the action time of 2-5min, can effectively kill escherichia coli, staphylococcus aureus, Candida albicans, sterilizing rate is 99.99%; Safety and stability is pollution-free.
2, use easy to carryly, antiinflammatory is quick, can alleviate and remove patient's pain, the symptom such as swell, itch, and makes the faster healing of focus.
3, directly act on anoderm cell and mucous membrane of rectum epithelial cell, effectively sterilization, antibacterial, antiinflammatory.Impel the focus cell to accelerate metabolism, shorten stable treatment maintenance and the maintenance of the course of disease.
4, marine bioactivity material and focus cell organically combine, accelerating the focus cell turnover regenerates, thereby remove abnormality cell and the new healthy cell of hypertrophy, useful and do not injure healthy cell to cell, namely to human body skin, anoderm and mucous membrane of rectum epithelium do not stimulate irritated side effect.
5, the occupation mode of colorless and odorless and safe and convenient can make the patient get timely medical treatment, maintain, with cleaning, and effectively finish the focus cell-targeting is repaired and maintenance, the focus cell is exhaled the old and inhale the new, accelerate metabolism, thereby recover and alleviate the symptom of patient's piles, reduce operative treatment and can accelerate the wound healing of hands postoperative patient, lay good treatment basic guarantee for stopping palindromia.
Preferably, in order to obtain better hemorrhoid antiinflammatory effect, described marine organisms hemorrhoid antiinflammatory maintenance liquid is characterized in that, comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.5 ~ 3.5%;
Sargassum polysaccharides 2.5 ~ 3.5%;
Cecropin 6.5 ~ 7.5%;
N-acetylmuramide lycanohydrlase 2.5 ~ 3.0%;
Borneolum Syntheticum 1.5 ~ 2.0%;
Water 80.5 ~ 84.5%.
Preferably, described Sargassum polysaccharides is one or more the mixture in fucoidin, chlorella polysaccharide, blue algae polysaccharide or the red seaweed polysaccharide.
Preferably, in order to make the marine organisms hemorrhoid antiinflammatory maintenance liquid of cleaner health, described water is pure water.
It is the cecropin described in the CN101104637B that described cecropin can adopt notification number, can certainly adopt other cecropin.
Embodiment 2
Present embodiment provides a kind of preparation method of the marine organisms hemorrhoid antiinflammatory maintenance liquid for embodiment 1, may further comprise the steps:
Step S10: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 30 ~ 35 ℃ the water, mix to get mixed liquor A;
Step S20: add the cecropin of proportional quantity in the mixed liquor A, mix to get mixed liquid B;
Step S30: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix to get described marine organisms hemorrhoid antiinflammatory maintenance liquid.
The preparation method of the marine organisms hemorrhoid antiinflammatory maintenance liquid of present embodiment, because order by merging and the mixing condition of each material are comparatively reasonable, so that the marine organisms tinea unguium that makes by preparation method of the present invention, each component mix homogeneously of paronychia treatment liquid, good stability.
In the present embodiment, more even for what each component can be mixed, preferred, among the described step S10, among the described step S10, the time that mixes is 10 ~ 20 minutes.
In the present embodiment, more even for what each component can be mixed, preferred, among the described step S10, among the described step S20, the time that mixes is 3 ~ 7 minutes.
In the present embodiment, more even for what each component can be mixed, preferred, among the described step S10, among the described step S 30, the time that mixes is 3 ~ 7 minutes.
In the present embodiment, preferred, in order to make more portable marine organisms hemorrhoid antiinflammatory maintenance liquid, after step S30, also comprise step S40: packing is but carried out in described marine organisms hemorrhoid antiinflammatory maintenance liquid cooling afterwards.
Embodiment 3
Present embodiment provides a kind of marine organisms hemorrhoid antiinflammatory maintenance liquid, comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.0%;
Fucoidin 2.0%;
Cecropin 6.0%;
N-acetylmuramide lycanohydrlase 2.0%;
Borneolum Syntheticum 1.0%;
Pure water 87%.
Marine organisms hemorrhoid antiinflammatory maintenance liquid and preparation method thereof in the present embodiment is:
Step S301: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 30 ℃ the water, mix 10 minutes mixed liquor A;
Step S302: add the cecropin of proportional quantity in the mixed liquor A, mix 3 minutes mixed liquid B;
Step S303: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 3 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Present embodiment sees Table 1 to the effect of hemorrhoid antiinflammatory maintenance.
Embodiment 4
Present embodiment provides a kind of marine organisms hemorrhoid antiinflammatory maintenance liquid, comprises each component of following percetage by weight:
Carboxymethyl chitosan 4.0%;
Red seaweed polysaccharide 4.0%;
Cecropin 8.0%;
N-acetylmuramide lycanohydrlase 3.5%;
Borneolum Syntheticum 2.5%;
Pure water 78%.
Marine organisms hemorrhoid antiinflammatory maintenance liquid and preparation method thereof in the present embodiment is:
Step S401: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 35 ℃ the water, mix 20 minutes mixed liquor A;
Step S402: add the cecropin of proportional quantity in the mixed liquor A, mix 7 minutes mixed liquid B;
Step S403: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 7 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Present embodiment sees Table 2 to the effect of hemorrhoid antiinflammatory maintenance.
Embodiment 5
Present embodiment provides a kind of marine organisms hemorrhoid antiinflammatory maintenance liquid, comprises each component of following percetage by weight:
Carboxymethyl chitosan 3.5%;
Blue algae polysaccharide 3.5%;
Cecropin 7.5%;
N-acetylmuramide lycanohydrlase 3.0%;
Borneolum Syntheticum 2.0%;
Pure water 80.5%.
Marine organisms hemorrhoid antiinflammatory maintenance liquid and preparation method thereof in the present embodiment is:
Step S501: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 33 ℃ the water, mix 15 minutes mixed liquor A;
Step S502: add the cecropin of proportional quantity in the mixed liquor A, mix 5 minutes mixed liquid B;
Step S503: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 5 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Step S503: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 5 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Present embodiment sees Table 3 to the effect of hemorrhoid antiinflammatory maintenance.
Embodiment 6
Present embodiment provides a kind of marine organisms hemorrhoid antiinflammatory maintenance liquid, comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.5%;
Chlorella polysaccharide 2.5%;
Cecropin 6.5%;
N-acetylmuramide lycanohydrlase 2.5%;
Borneolum Syntheticum 1.5%;
Pure water 84.5%.
Marine organisms hemorrhoid antiinflammatory maintenance liquid and preparation method thereof in the present embodiment is:
Step S501: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 33 ℃ the water, mix 15 minutes mixed liquor A;
Step S502: add the cecropin of proportional quantity in the mixed liquor A, mix 5 minutes mixed liquid B;
Step S503: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 5 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Step S503: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix 5 minutes described marine organisms hemorrhoid antiinflammatory maintenance liquid.
Table 1
Table 2
Table 3
Above clinical trial certificate, marine organisms hemorrhoid antiinflammatory maintenance liquid of the present invention can be high for the treatment cure rate of hemorrhoid, and produce effects is fast.
It should be noted that at last: above embodiment only in order to technical scheme of the present invention to be described, is not intended to limit; Although with reference to previous embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that: it still can be made amendment to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement; And these modifications or replacement do not make the essence of appropriate technical solution break away from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (9)
1. a marine organisms hemorrhoid antiinflammatory maintenance liquid is characterized in that, comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.0 ~ 4.0%;
Sargassum polysaccharides 2.0 ~ 4.0%;
Cecropin 6.0 ~ 8.0%;
N-acetylmuramide lycanohydrlase 2.0 ~ 3.5%;
Borneolum Syntheticum 1.0 ~ 2.5%;
Water 78 ~ 87%.
2. marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 1 is characterized in that, comprises each component of following percetage by weight:
Carboxymethyl chitosan 2.5 ~ 3.5%;
Sargassum polysaccharides 2.5 ~ 3.5%;
Cecropin 6.5 ~ 7.5%;
N-acetylmuramide lycanohydrlase 2.5 ~ 3.0%;
Borneolum Syntheticum 1.5 ~ 2.0%;
Water 80.5 ~ 84.5%.
3. marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 1 and 2 is characterized in that, described Sargassum polysaccharides is one or more the mixture in fucoidin, chlorella polysaccharide, blue algae polysaccharide or the red seaweed polysaccharide.
4. marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 1 and 2 is characterized in that described water is pure water.
5. the preparation method such as each described marine organisms hemorrhoid antiinflammatory maintenance liquid of claim 1-4 is characterized in that, comprises the steps:
Step S10: add carboxymethyl chitosan and the Sargassum polysaccharides of proportional quantity in 30 ~ 35 ℃ the water, mix to get mixed liquor A;
Step S20: add the cecropin of proportional quantity in the mixed liquor A, mix to get mixed liquid B;
Step S30: add N-acetylmuramide lycanohydrlase and the Borneolum Syntheticum of proportional quantity in the mixed liquid B, mix to get described marine organisms hemorrhoid antiinflammatory maintenance liquid.
6. the preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 5 is characterized in that, among the described step S10, the time that mixes is 10 ~ 20 minutes.
7. the preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 5 is characterized in that, among the described step S20, the time that mixes is 3 ~ 7 minutes.
8. the preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 5 is characterized in that, among the described step S 30, the time that mixes is 3 ~ 7 minutes.
9. the preparation method of marine organisms hemorrhoid antiinflammatory maintenance liquid according to claim 5 is characterized in that, also comprises step S40 after step S30: packing is but carried out in described marine organisms hemorrhoid antiinflammatory maintenance liquid cooling afterwards.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105463636A CN103041375A (en) | 2011-12-16 | 2012-12-14 | Marine biological hemorrhoidal anti-inflammatory repairing lotion and preparation method thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110423421.1 | 2011-12-16 | ||
| CN2011104234211A CN102552885A (en) | 2011-12-16 | 2011-12-16 | Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms |
| CN2012105463636A CN103041375A (en) | 2011-12-16 | 2012-12-14 | Marine biological hemorrhoidal anti-inflammatory repairing lotion and preparation method thereof |
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| CN103041375A true CN103041375A (en) | 2013-04-17 |
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| CN2011104234211A Pending CN102552885A (en) | 2011-12-16 | 2011-12-16 | Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms |
| CN2012105463636A Pending CN103041375A (en) | 2011-12-16 | 2012-12-14 | Marine biological hemorrhoidal anti-inflammatory repairing lotion and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102552885A (en) * | 2011-12-16 | 2012-07-11 | 青岛海芬海洋生物科技有限公司 | Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms |
| CN103393713B (en) * | 2013-08-09 | 2016-05-11 | 北京宝润堂生物科技有限公司 | The application in the medicine of preparation treatment constipation of hyaluronic acid and salt thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380064A (en) * | 2001-03-22 | 2002-11-20 | 贺利氏古萨两合有限公司 | Method for producing antibiotic preparation and its application |
| CN102552885A (en) * | 2011-12-16 | 2012-07-11 | 青岛海芬海洋生物科技有限公司 | Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms |
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- 2012-12-14 CN CN2012105463636A patent/CN103041375A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380064A (en) * | 2001-03-22 | 2002-11-20 | 贺利氏古萨两合有限公司 | Method for producing antibiotic preparation and its application |
| CN102552885A (en) * | 2011-12-16 | 2012-07-11 | 青岛海芬海洋生物科技有限公司 | Piles and anus internal epithelium and rectum mucous epithelium cell anti-inflammation celltrex made of marine organisms |
Non-Patent Citations (2)
| Title |
|---|
| 《中国医药指南》 20110731 刘淑鑫等 "溶菌酶医学应用研究概况" 第9卷, 第21期 * |
| 刘淑鑫等: ""溶菌酶医学应用研究概况"", 《中国医药指南》 * |
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Application publication date: 20130417 |