CN103041136B - Chinese medicine preparation for treating hypertension - Google Patents

Chinese medicine preparation for treating hypertension Download PDF

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CN103041136B
CN103041136B CN201310040477.8A CN201310040477A CN103041136B CN 103041136 B CN103041136 B CN 103041136B CN 201310040477 A CN201310040477 A CN 201310040477A CN 103041136 B CN103041136 B CN 103041136B
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radix
chinese medicine
medicine preparation
crude drug
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CN103041136A (en
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黄晶晶
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Beijing ward Institute of traditional Chinese Medicine
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黄晶晶
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Abstract

The invention relates to a Chinese medicine preparation for treating hypertension. The Chinese medicine preparation is characterized by being prepared from the following bulk pharmaceutical chemicals in parts by weight: 12-18 parts of radix astragali, 12-18 parts of concha haliotidis, 10-14 parts of apocynum venetum, 10-14 parts of radix scrophulariae, 10-14 parts of semen cassiae, 12-18 parts of roots bark of white mulberry, 12-18 parts of honeysuckle, 12-18 parts of dried rehmannia roots, 5-9 parts of radix puerariae, 2-4 parts of rhizoma coptidis, 5-9 parts of rhubarb, 4-6 parts of radix bupleuri, 2-4 parts of fossil fragments, 12-18 parts of magnetite, 10-14 parts of hawthorn, 12-18 parts of selfheal, 4-6 parts of motherwort, 5-9 parts of fruits of Chinese wolfberry, 4-6 parts of sophora flowers, 5-9 parts of radix cynanchi atrati, 4-6 parts of dried lily bulbs and 5-9 parts of lotus seeds. The Chinese medicine preparation disclosed by the invention has the advantages of distinct curative effect, small side effects, simplicity in preparation and low cost; and through clinical validation, the effective hypertension treatment rate of the Chinese medicine preparation disclosed by the invention is 99%.

Description

A kind ofly treat hypertensive Chinese medicine preparation
Technical field
The present invention relates to technical field of traditional Chinese medicine pharmacy, particularly relate to a kind of hypertensive Chinese medicine preparation for the treatment of.
Background technology
Hypertension is a kind ofly to take arteriotony and continue to raise be the chronic disease of main manifestations, and clinical symptoms shows as dizzy, headache, cardiopalmus, insomnia, irritated etc.; Often cause the pathological changes of the vitals such as the heart, brain, kidney and occur corresponding consequence.The blood pressure standard that World Health Organization's suggestion is used is: all normal adult systolic pressures should be less than or equal to 140mmHg, diastolic pressure is less than or equal to 90mmHg, that is systolic pressure is between 141-159mmHg, diastolic pressure is borderline hypertension between 91-94mmHg, if have the meansigma methods of double diastolic pressure more than 91mmHg, just can be diagnosed as hypertension.Hypertension is modal cardiovascular diseases, has become the great public health problem in global range.
At present, treating hypertensive medicine numerous, is mostly to take blood circulation promoting and blood stasis dispelling, blood vessel dilating as main, can only relief of symptoms, and result is to cure the symptoms, not the disease; As long-term taking, also have very large side effect.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of hypertensive Chinese medicine preparation for the treatment of, the present invention has evident in efficacy, and side effect is little, and preparation is simple, the advantage that cost is low.
Treat a hypertensive Chinese medicine preparation, it is characterized in that: the crude drug by following weight portion is made: Radix Astragali 12-18 part, Concha Haliotidis 12-18 part, Herba Apocyni veneti 10-14 part, Radix Scrophulariae 10-14 part, Semen Cassiae 10-14 part, Cortex Mori 12-18 part, Flos Lonicerae 12-18 part, Radix Rehmanniae 12-18 part, Radix Puerariae 5-9 part, Rhizoma Coptidis 2-4 part, Radix Et Rhizoma Rhei 5-9 part, Radix Bupleuri 4-6 part, Os Draconis 2-4 part, Magnetitum 12-18 part, Fructus Crataegi 10-14 part, Spica Prunellae 12-18 part, Herba Leonuri 4-6 part, Fructus Lycii 5-9 part, Flos Sophorae 4-6 part, Radix Cynanchi Atrati 5-9 part, Bulbus Lilii 4-6 part, Semen Nelumbinis 5-9 part.
The hypertensive Chinese medicine preparation of described treatment, its preferably: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 15 parts of Concha Haliotidis, 12 parts of Herba Apocyni venetis, 12 parts of Radix Scrophulariaes, 12 parts of Semen Cassiaes, 15 parts of Cortex Mori, 15 parts of Flos Loniceraes, 15 parts of Radix Rehmanniae, 7 parts of Radix Puerariaes, 3 parts of Rhizoma Coptidis, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Bupleuri, 3 parts of Os Draconis, 15 parts of Magnetitums, 12 parts of Fructus Crataegis, 15 parts of Spica Prunellaes, 5 parts of Herba Leonuris, 7 parts of Fructus Lycii, 5 parts, Flos Sophorae, 7 parts of Radix Cynanchi Atratis, 5 parts of Bulbus Liliies, 7 parts, Semen Nelumbinis.
The preparation method of the described hypertensive Chinese medicine preparation for the treatment of, comprises the following steps: according to described parts by weight, take each crude drug, pack after each crude drug taking is mixed, sterilized.
Usage and consumption: the Chinese medicine preparation of making is added to 2-3 times of decocting and boil, be heated to boiling point, decoct 30-50 minute, filter to obtain medicinal liquid, by the method, decoct three times continuously, by three times, decoct gained medicinal liquid and merge, be equally divided into two parts, patient every day early, respectively take portion evening; It within 7 days, is a course for the treatment of.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
The Radix Astragali: sweet, tepor; Effect: polishing consolidating superficial resistance, holder skin ulcer granulation promoting.
Concha Haliotidis: salty, flat, enter liver, kidney channel; Effect: suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving.
Herba Apocyni veneti: sweet, micro-hardship, cool in nature, return Liver Channel; Effect: relieve inflammation or internal heat, blood pressure lowering, heart tonifying, diuresis.
Radix Scrophulariae: sweet in the mouth, hardship, salty, cold nature, returns lung, stomach, kidney channel; Effect: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
Semen Cassiae: sweet, bitter, salty, be slightly cold, return liver, large intestine channel; Effect: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.
Cortex Mori: sweet, cold, return lung meridian; Effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.
Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp; Effect: heat-clearing and toxic substances removing, wind-heat dissipating.
Radix Rehmanniae: sweetness and bitterness, cool, enter the heart, liver, kidney channel; Effect:: heat clearing away, the YIN nourishing of promoting the production of body fluid, nourishes blood.
Radix Puerariae: sweet, pungent, cool, return spleen, stomach warp; Effect: expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, yang invigorating antidiarrheal.
Rhizoma Coptidis: hardship, cold, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel; Effect: heat clearing and damp drying, eliminating fire and detoxication.
Radix Et Rhizoma Rhei: hardship, cold, return spleen, stomach, large intestine, liver, pericardium channel; Effect: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.
Radix Bupleuri: hardship, be slightly cold, return liver, gallbladder meridian; Effect: reconciling superficies and interior, soothing the liver, yang invigorating.
Os Draconis: sweet, puckery, flat; Effect: calmness, arresting sweating arresting seminal emission, promoting tissue regeneration and ulcer healing.
Magnetitum: salty, cold, return liver, the heart, kidney channel; Effect: suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, helping inspiration to relieve asthma.
Fructus Crataegi: sour, sweet, tepor, return spleen, stomach, Liver Channel; Effect: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.
Spica Prunellae: pungent, bitter, cold, return liver, gallbladder meridian.Relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence; Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.
Herba Leonuri: bitter, pungent, be slightly cold, return liver, pericardium channel; Effect: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.
Fructus Lycii: sweet, flat, return liver, kidney channel; Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.
Flos Sophorae: hardship, be slightly cold, return liver, large intestine channel; Effect: cooling blood for hemostasis, purging liver-fire.
Radix Cynanchi Atrati: bitter, salty, cold, return stomach, liver, kidney channel; Effect: clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.
Bulbus Lilii: sweet, cold, GUIXIN, lung meridian; Effect: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.
Semen Nelumbinis: sweet, puckery, flat, return spleen, kidney, heart channel; Effect: spleen reinforcing antidiarrheal, kidney tonifying arresting seminal emission, tranquilizing by nourishing the heart.
Above-mentioned each crude drug and the made Chinese medicine preparation of proportioning thereof for the present invention, have that nourishing the kidney and liver, blood pressure lowering relieve dizziness, high fever, infantile convulsions, epilepsy, etc., an effect of circulation of qi promoting intestinal stasis relieving, vessel softening, thereby reach the hypertensive object for the treatment of.
The beneficial effect that the present invention compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience guidance, choose each crude drug and proportioning thereof, utilize its mutual collaborative or resistant function, improve curative effect, to adapt to the treatment requirement of the complicated state of an illness; The present invention has evident in efficacy, and side effect is little, and preparation is simple, the advantage that cost is low; Through clinical verification, it is 99% that the present invention treats hypertension effective percentage.
The specific embodiment
Embodiment 1:
Treat a hypertensive Chinese medicine preparation, by the crude drug of following weight portion, made: 15 parts of the Radixs Astragali, 15 parts of Concha Haliotidis, 12 parts of Herba Apocyni venetis, 12 parts of Radix Scrophulariaes, 12 parts of Semen Cassiaes, 15 parts of Cortex Mori, 15 parts of Flos Loniceraes, 15 parts of Radix Rehmanniae, 7 parts of Radix Puerariaes, 3 parts of Rhizoma Coptidis, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Bupleuri, 3 parts of Os Draconis, 15 parts of Magnetitums, 12 parts of Fructus Crataegis, 15 parts of Spica Prunellaes, 5 parts of Herba Leonuris, 7 parts of Fructus Lycii, 5 parts, Flos Sophorae, 7 parts of Radix Cynanchi Atratis, 5 parts of Bulbus Liliies, 7 parts, Semen Nelumbinis.
The preparation method of the described hypertensive Chinese medicine preparation for the treatment of, comprises the following steps: according to described parts by weight, take each crude drug, pack after each crude drug taking is mixed, sterilized.
Embodiment 2:
Treat a hypertensive Chinese medicine preparation, by the crude drug of following weight portion, made: 12 parts of the Radixs Astragali, 12 parts of Concha Haliotidis, 10 parts of Herba Apocyni venetis, 10 parts of Radix Scrophulariaes, 10 parts of Semen Cassiaes, 12 parts of Cortex Mori, 12 parts of Flos Loniceraes, 12 parts of Radix Rehmanniae, 5 parts of Radix Puerariaes, 2 parts of Rhizoma Coptidis, 5 parts of Radix Et Rhizoma Rhei, 4 parts of Radix Bupleuri, 2 parts of Os Draconis, 12 parts of Magnetitums, 10 parts of Fructus Crataegis, 12 parts of Spica Prunellaes, 4 parts of Herba Leonuris, 5 parts of Fructus Lycii, 4 parts, Flos Sophorae, 5 parts of Radix Cynanchi Atratis, 4 parts of Bulbus Liliies, 5 parts, Semen Nelumbinis.
The preparation method of the described hypertensive Chinese medicine preparation for the treatment of, comprises the following steps: according to described parts by weight, take each crude drug, pack after each crude drug taking is mixed, sterilized.
Embodiment 3:
Treat a hypertensive Chinese medicine preparation, by the crude drug of following weight portion, made: 18 parts of the Radixs Astragali, 18 parts of Concha Haliotidis, 14 parts of Herba Apocyni venetis, 14 parts of Radix Scrophulariaes, 14 parts of Semen Cassiaes, 18 parts of Cortex Mori, 18 parts of Flos Loniceraes, 18 parts of Radix Rehmanniae, 9 parts of Radix Puerariaes, 4 parts of Rhizoma Coptidis, 9 parts of Radix Et Rhizoma Rhei, 6 parts of Radix Bupleuri, 4 parts of Os Draconis, 18 parts of Magnetitums, 14 parts of Fructus Crataegis, 18 parts of Spica Prunellaes, 6 parts of Herba Leonuris, 9 parts of Fructus Lycii, 6 parts, Flos Sophorae, 9 parts of Radix Cynanchi Atratis, 6 parts of Bulbus Liliies, 9 parts, Semen Nelumbinis.
The preparation method of the described hypertensive Chinese medicine preparation for the treatment of, comprises the following steps: according to described parts by weight, take each crude drug, pack after each crude drug taking is mixed, sterilized.
Experimental example:
One, clinical data: adopt the present invention to treat hyperpietic's 313 examples, male 168 examples wherein, female's 145 examples, the oldest 75 years old, minimum 26 years old of age.
Two, clinical symptoms: dizzy, headache, cardiopalmus, insomnia, agitation etc.; Systolic pressure is more than or equal to 141mmHg, and diastolic pressure is more than or equal to 91mmHg.
Three, Therapeutic Method: the Chinese medicine preparation of making is added to 2-3 times of decocting and boil, be heated to boiling point, decoct 30-50 minute, filter to obtain medicinal liquid, by the method, decoct three times continuously, by three times, decoct gained medicinal liquid and merge, be equally divided into two parts, patient every day early, respectively take portion evening; It within 7 days, is a course for the treatment of.
Four, the standard of curative effect evaluation:
Cure: transference cure, it is normal that blood pressure recovers;
Take a turn for the better: symptom is obviously improved, and blood pressure has clear improvement;
Do not heal: symptom is not improved or deterioration person, blood pressure does not recover.
Five, model case:
1, Lin, man, 69 years old, retirement, suffered from hypertension 22 years, Symptoms for having a dizzy spell, have palpitation, myasthenia of limbs etc., systolic pressure is at 160-220mmHg, diastolic pressure is at 100-120mmHg; Took multi-medicament and do not cure, and took three of the Chinese medicine preparation of the present invention symptom course for the treatment of and obviously improve, systolic pressure is down to 150mmHg, and diastolic pressure, at 100mmHg, is taken six recoveries from illness courses for the treatment of, and systolic pressure is at 140mmHg, and diastolic pressure is at 90mmHg; Follow up a case by regular visits to 5 years, not recurrence.
2, Cui, man, 33 years old, civil servant, suffered from hypertension 7 years, and Symptoms is headache, and dizzy etc., systolic pressure is at 160-170mmHg, and diastolic pressure is at 100-110mmHg; Took multi-medicament and do not cure, and took two of the Chinese medicine preparation of the present invention symptom course for the treatment of and obviously improve, systolic pressure is down to 140mmHg, and diastolic pressure, at 95mmHg, is taken five recoveries from illness courses for the treatment of, and systolic pressure is at 130mmHg, and diastolic pressure is at 80mmHg; Follow up a case by regular visits to 2 years, not recurrence.
3, Lv, female, 45 years old, office worker, suffered from hypertension 3 years, and Symptoms is dizziness tinnitus, cardiopalmus, insomnia, being irritable and getting angry easily etc., systolic pressure is at 150-160mmHg, and diastolic pressure is at 95-110mmHg; Took multi-medicament and do not cure, and took one of the Chinese medicine preparation of the present invention symptom course for the treatment of and obviously improve, systolic pressure is down to 140mmHg, and diastolic pressure, at 100mmHg, is taken three recoveries from illness courses for the treatment of, and systolic pressure is at 125mmHg, and diastolic pressure is at 80mmHg; Follow up a case by regular visits to 3 years, not recurrence.
4, Shao so-and-so, man, 52 years old, teacher, suffered from hypertension 13 years, Symptoms is headache, order is swollen, irritated irritability etc., systolic pressure is at 160-180mmHg, diastolic pressure is at 100-120mmHg; Took multi-medicament and do not cure, and took two of the Chinese medicine preparation of the present invention symptom course for the treatment of and obviously improve, systolic pressure is down to 150mmHg, and diastolic pressure, at 95mmHg, is taken four recoveries from illness courses for the treatment of, and systolic pressure is at 130mmHg, and diastolic pressure is at 75mmHg; Follow up a case by regular visits to so far, not recurrence.
Six, therapeutic outcome:
Adopt the present invention to treat altogether hyperpietic's 313 examples, through the treatment of 2-6 the course for the treatment of, wherein cure 228 examples, 83 examples that take a turn for the better, 2 examples that do not heal, average effective time is 8.5 days, effective percentage is 99%; Result shows, the present invention has evident in efficacy, and side effect is little.

Claims (1)

1. a preparation method for the treatment of hypertensive Chinese medicine preparation, comprise the following steps: according to parts by weight, take each crude drug: 15 parts of the Radixs Astragali, 15 parts of Concha Haliotidis, 12 parts of Herba Apocyni venetis, 12 parts of Radix Scrophulariaes, 12 parts of Semen Cassiaes, 15 parts of Cortex Mori, 15 parts of Flos Loniceraes, 15 parts of Radix Rehmanniae, 7 parts of Radix Puerariaes, 3 parts of Rhizoma Coptidis, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Bupleuri, 3 parts of Os Draconis, 15 parts of Magnetitums, 12 parts of Fructus Crataegis, 15 parts of Spica Prunellaes, 5 parts of Herba Leonuris, 7 parts of Fructus Lycii, 5 parts, Flos Sophorae, 7 parts of Radix Cynanchi Atratis, 5 parts of Bulbus Liliies, 7 parts, Semen Nelumbinis, pack after each crude drug taking is mixed, sterilized.
CN201310040477.8A 2013-02-02 2013-02-02 Chinese medicine preparation for treating hypertension Expired - Fee Related CN103041136B (en)

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CN103349739B (en) * 2013-06-14 2015-08-19 魏娜 A kind of Blood-pressure-lowerhealth-care health-care oral liquid and preparation method thereof
CN103610866B (en) * 2013-11-25 2015-07-29 济南伟传信息技术有限公司 A kind of Chinese medicine of Hypertension
CN103705596B (en) * 2014-01-10 2015-11-25 浙江科技学院 A kind of Chinese hypotensor and preparation method thereof
CN103860653B (en) * 2014-03-10 2016-05-11 中南大学 The hypertensive compound blood pressure reducing capsule of treatment-refractory and preparation and application
CN104758652A (en) * 2015-03-26 2015-07-08 王浩 Traditional Chinese medicine composition for treating dizziness
CN104815061A (en) * 2015-04-24 2015-08-05 王敬侠 Traditional Chinese medicine composition for treating hypertension and preparation method of traditional Chinese medicine composition

Non-Patent Citations (1)

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