CN103041129B - Traditional Chinese medicine composition for treating pneumonia - Google Patents
Traditional Chinese medicine composition for treating pneumonia Download PDFInfo
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- CN103041129B CN103041129B CN201310040396.8A CN201310040396A CN103041129B CN 103041129 B CN103041129 B CN 103041129B CN 201310040396 A CN201310040396 A CN 201310040396A CN 103041129 B CN103041129 B CN 103041129B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating pneumonia, and relates to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following active ingredients in parts by weight: 20-30 parts of hedyotis diffusa, 20-30 parts of folium isatidis, 12-18 parts of fructus arctii, 12-18 parts of herba taraxaci, 12-18 parts of officinal magnolia bark and 6-10 parts of thunberg fritillary bulb. The traditional Chinese medicine composition disclosed by the invention improves the therapeutic effect on a child suffering partial wind-heat type pneumonia, reduces the pain of the child, shortens the course of treatment, ensures few complications and increases social and economic benefits.
Description
Technical field
The invention belongs to Chinese medicine technical field, be specifically related to a kind of Chinese medicine composition for the treatment of pneumonia.
Background technology
Infantile pneumonia is a kind of disease common in children's's Pulmonary Diseases, take generate heat, harmony in cough, flaring of nares out of breath, sputum, very tears obturation, opening mouth and lifting shoulder due to dyspnea, shake body and pick tripe as its Clinical symptoms.How continue method after ailment said due to cold or exposure flu, children's's vital QI cannot conquer pathogen, supervention primary disease.Children's experiences ailment said due to cold or exposure, or from fur, or enters from mouth and nose, invades lung and defends, and Lung Qi obstraction, clearly respectful makes not all rightly, can occur pneumonia cough, and ailment said due to cold or exposure has the difference of the cold folder of folder heat, can produce cold closed lung or wind heat is closed lung, wherein with wind heat, closes lung the most common.Western medical treatment method only, children's endures the misery of transfusion acupuncture treatment to the fullest extent, and the state of an illness easily repeatedly, and antibiotic application easily produces drug resistance, application Chinese medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, symptomatic treatment assistant is controlled infantile pneumonia can Shorten the Treatment Process, the more effective control state of an illness, mitigation symptoms, prevention and minimizing complication occur, reduce recurrence rate, and letter, just, test, honest and clean, have good Social benefit and economic benefit.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition and application that coordinates western medicine pneumonia.This Chinese medicine composition can improve the treatment curative effect of hemiplegia pattern of fever children pneumonia, alleviates infant misery, Shorten the Treatment Process, and few intercurrent disease, improves Social benefit and economic benefit.
The object of the present invention is achieved like this:
A kind of Chinese medicine composition for the treatment of pneumonia of the present invention, is prepared from by the raw material of following weight portion: Herba Hedyotidis Diffusae 20-30 part, Folium Isatidis 20-30 part, Fructus Arctii 12-18 part, Herba Taraxaci 12-18 part, Cortex Magnoliae Officinalis 12-18 part, Bulbus Fritillariae Thunbergii 6-10 part.
The present invention treats the Chinese medicine composition of pneumonia, and preferably the raw material by following weight portion is prepared from: 25 parts of Herba Hedyotidis Diffusaes, 25 parts of Folium Isatidiss, 15 parts of Fructus Arctiis, 15 parts of Herba Taraxacis, 15 parts of Cortex Magnoliae Officinalis, 8 parts of Bulbus Fritillariae Thunbergiis.
Further preferably, to treat the Chinese medicine composition of pneumonia be oral liquid in the present invention.
The present invention treats the most applicable treatment hemiplegia of the Chinese medicine composition pattern of fever children pneumonia of pneumonia, evident in efficacy.
The preparation method that the present invention treats the Chinese medicine composition oral liquid of pneumonia comprises the steps:
(1) get Herba Hedyotidis Diffusae, Folium Isatidis, Fructus Arctii, Herba Taraxaci, Cortex Magnoliae Officinalis and the Bulbus Fritillariae Thunbergii of recipe quantity, clean roguing, dry, pulverize;
(2) more above-mentioned graininess medical material is added to water and cover powder 2cm, soak 1-1.2h, pull medical material out and put multi-functional extraction and decoct with water secondary in filling with, add up for the first time the water that medical material 8-10 doubly measures, decoct 2h, get decocting liquid, filter, add up for the second time the water that medical material 6-8 doubly measures, decoct 1h, get twice decocting liquid and merge, filter the concentrated solution that while being concentrated into 90 ℃, relative density is 1.15g/mL;
(3) concentrated solution is set to 0 to-5 ℃ of deepfreeze 24h, cold preservation liquid is added to 0.3% filter aid kieselguhr, filter, filtrate reconcentration to every milliliter containing 2-3g crude drug amount, set to 0-5 ℃ of deepfreeze 24h, cold preservation liquid filtered, add or do not add correctives after pack and obtain oral liquid.
According to Chinese medicine Historical Data Data About, the pharmacologically active of the traditional Chinese medicinal material raw materials that the present invention adopts and source are as follows:
Herba Hedyotidis Diffusae: latin name Herba Hedyotis Diffusae, has the effect of heat-clearing and toxic substances removing, dampness removing; Cure mainly: dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Cancerous protuberance.Be selected from the dry herb of Maguireothamnus speciosus Herba Hedyotidis Diffusae Hedyotis diffusa Willd..
Fructus Arctii: there is the effect of dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling, cure mainly cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule not thoroughly, rubella pruritus, sore swollen toxin.Be selected from the dry mature fruit of feverfew Fructus Arctii Arctium lappa L..
Folium Isatidis: heat clearing away, removing toxic substances, removing heat from blood, hemostasis.Control epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Select the dried leaves of cruciferae isatis Isatis indigotica Fort..
Herba Taraxaci: there is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effect of inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Be selected from the herb of dry Herba Taraxaci.
Cortex Magnoliae Officinalis: main warming middle-JIAO, QI invigorating, the expectorant therapeutic method to keep the adverse QI flowing downwards, controls cholera and stomachache, distension, cold in the stomach is contrary, and vomiting is more than in the heart, lets out dysentery, drenches dew, and except frightened, going or staying heat, stops stuffy sensation with restlessness, thick the intestines and stomach.Select dry dried bark, root bark and the branch skin of Magnoliacea plant Cortex Magnoliae Officinalis Magnolia officinalis Rehd. et Wils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils..
Bulbus Fritillariae Thunbergii: removing heat-phlegm, powder detoxifcation.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.Select the dry bulb of liliaceous plant Bulbus Fritillariae Thunbergii Fritillaria thunbergii Miq..
By experimental study, show, Chinese medicine composition of the present invention coordinates the evident in efficacy of the western medicine pattern of fever children pneumonia such as antibiotic.Be embodied in: in heating, eliminate the phlegm and cough with asthma regression time, average length of hospitalization each side, test group and matched group all have significant difference.This absolutely proves, add by the curative effect of the therapy of combining Chinese and Western medicine hemiplegia pattern of fever pneumonia of Chinese medicine composition of the present invention and treat good effect compared with simple western medicine, in effective percentage, minimizing antibiotic use, all there is clear superiority, can improve the treatment curative effect of hemiplegia pattern of fever children pneumonia, alleviate infant misery, Shorten the Treatment Process, few intercurrent disease, improves Social benefit and economic benefit.
The specific embodiment
Be below specific embodiments of the invention, technical scheme of the present invention is done to further description, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.
the preparation of embodiment 1 Chinese medicine oral liquid
Crude drug prescription: 250 grams of Herba Hedyotidis Diffusaes, 250 grams of Folium Isatidiss, 150 grams of Fructus Arctiis, 150 grams of Herba Taraxacis, 150 grams of Cortex Magnoliae Officinalis, 80 grams of Bulbus Fritillariae Thunbergiis.
Oral liquor:
(1) get Herba Hedyotidis Diffusae, Folium Isatidis, Fructus Arctii, Herba Taraxaci, Cortex Magnoliae Officinalis and the Bulbus Fritillariae Thunbergii of recipe quantity, clean roguing, dry, pulverize;
(2) more above-mentioned graininess medical material is added to water and cover powder 2cm, soak 1-1.2h, pull medical material out and put multi-functional extraction and decoct with water secondary in filling with, add up for the first time the water of 10 times of amounts of medical material, decoct 2h, get decocting liquid, filter, add up for the second time the water of 8 times of amounts of medical material, decoct 1h, get twice decocting liquid and merge, filter the concentrated solution that while being concentrated into 90 ℃, relative density is 1.15g/mL;
(3) concentrated solution is set to 0 to-5 ℃ of deepfreeze 24h, cold preservation liquid is added to 0.3% filter aid kieselguhr, filter, filtrate reconcentration containing 2.5g crude drug amount, sets to 0-5 ℃ of deepfreeze 24h to every milliliter, and cold preservation liquid is filtered, and packs and obtain oral liquid.
the preparation of embodiment 2 Chinese medicine oral liquid
Crude drug prescription: 200 grams of Herba Hedyotidis Diffusaes, 200 grams of Folium Isatidiss, 180 grams of Fructus Arctiis, 180 grams of Herba Taraxacis, 180 grams of Cortex Magnoliae Officinalis, 100 grams of Bulbus Fritillariae Thunbergiis.
Oral liquor:
(1) get Herba Hedyotidis Diffusae, Folium Isatidis, Fructus Arctii, Herba Taraxaci, Cortex Magnoliae Officinalis and the Bulbus Fritillariae Thunbergii of recipe quantity, clean roguing, dry, pulverize;
(2) more above-mentioned graininess medical material is added to water and cover powder 2cm, soak 1-1.2h, pull medical material out and put multi-functional extraction and decoct with water secondary in filling with, add up for the first time the water of 8 times of amounts of medical material, decoct 2h, get decocting liquid, filter, add up for the second time the water of 8 times of amounts of medical material, decoct 1h, get twice decocting liquid and merge, filter the concentrated solution that while being concentrated into 90 ℃, relative density is 1.15g/mL;
(3) concentrated solution is set to 0 to-5 ℃ of deepfreeze 24h, cold preservation liquid is added to 0.3% filter aid kieselguhr, filter, filtrate reconcentration containing 3g crude drug amount, sets to 0-5 ℃ of deepfreeze 24h to every milliliter, and cold preservation liquid is filtered, and packs and obtain oral liquid.
the preparation of embodiment 3 Chinese medicine oral liquid
Crude drug prescription: 300 grams of Herba Hedyotidis Diffusaes, 300 grams of Folium Isatidiss, 120 grams of Fructus Arctiis, 120 grams of Herba Taraxacis, 120 grams of Cortex Magnoliae Officinalis, 60 grams of Bulbus Fritillariae Thunbergiis.
Oral liquor:
(1) get Herba Hedyotidis Diffusae, Folium Isatidis, Fructus Arctii, Herba Taraxaci, Cortex Magnoliae Officinalis and the Bulbus Fritillariae Thunbergii of recipe quantity, clean roguing, dry, pulverize;
(2) more above-mentioned graininess medical material is added to water and cover powder 2cm, soak 1-1.2h, pull medical material out and put multi-functional extraction and decoct with water secondary in filling with, add up for the first time the water of 8 times of amounts of medical material, decoct 2h, get decocting liquid, filter, add up for the second time the water of 6 times of amounts of medical material, decoct 1h, get twice decocting liquid and merge, filter the concentrated solution that while being concentrated into 90 ℃, relative density is 1.15g/mL;
(3) concentrated solution is set to 0 to-5 ℃ of deepfreeze 24h, cold preservation liquid is added to 0.3% filter aid kieselguhr, filter, filtrate reconcentration containing 3g crude drug amount, sets to 0-5 ℃ of deepfreeze 24h to every milliliter, and cold preservation liquid is filtered, and packs and obtain oral liquid.
The effectiveness study of embodiment 4 Chinese medicine oral liquid to hemiplegia pattern of fever children pneumonia
Infantile pneumonia hemiplegia pattern of fever infant (3～10 years old) 49 examples, are divided into test group and matched group at random.Test group 25 examples wherein, matched group 24 examples.Two groups of infant sexes, age comparing difference not statistically significant, have comparability.
Matched group is only used western medical treatment, according to results such as routine blood test, antibacterial culturing, drug sensitive experiments, with reference to the < < pediatrics > > of king Mu Di (the 5th edition, Beijing, People's Health Publisher, 2002) content of 277-284 page, gives respectively the antibiotic such as penicillin, cephalo-type, azithromycin in conjunction with clinical sign, the treatments such as ganciclovir atomization suction, oxygen uptake; Test group adds the Chinese medicine oral liquid treatment of embodiment 1 preparation on western medical treatment basis, every day sooner or later each once, each 15mL.
Curative effect determinate standard is:
Effective: treatment 3d interior-heat moves back, cough, expectoration, tachypnea and breathe heavily and suppress transference cure or obviously alleviate;
Effective: treatment 3-7 d, heat is moved back, and cough alleviates, and tachypnea, breathes heavily and suppresses transference cure or alleviate;
Invalid: after treatment 7 d, heating, cough, expectoration, tachypnea, to breathe heavily that the symptom such as to suppress unchanged.
By clinical observation, find, test group bringing down a fever, cough-relieving, eliminate the phlegm, breathe heavily aspects such as suppressing extinction time and length of stay and all obviously shorten compared with matched group, have the significance difference opposite sex (
p< 0.05) or utmost point significant difference (
p< 0.01), refer to table 1.Clinical observation on the therapeutic effect is found, effective 21 examples of test group, effective 4 examples, invalid 0 example, total effective rate 100.0%; Effective 13 examples of matched group, effective 6 examples, invalid 5 examples, 79.17%, two group of total effective rate comparing difference of total effective rate has significance, in Table 2.
A table 1 liang group hemiplegia pattern of fever children pneumonia clinical symptoms sign is alleviated situation and hospital stays comparison (d)
With matched group comparison, *
p< 0.05, * *
p< 0.01
The curative effect comparison of table 2 liang group hemiplegia pattern of fever children pneumonia
By above clinical practice experimental study, show, Chinese medicine composition of the present invention coordinates the evident in efficacy of the western medicine pattern of fever children pneumonia such as antibiotic, in heating, eliminate the phlegm and cough with asthma regression time, average length of hospitalization each side, test group and matched group all have significant difference.Add by the curative effect of the therapy of combining Chinese and Western medicine hemiplegia pattern of fever pneumonia of Chinese medicine composition of the present invention and treat good effect compared with simple western medicine, in effective percentage, minimizing antibiotic use, all there is clear superiority, can improve the treatment curative effect of hemiplegia pattern of fever children pneumonia, alleviate infant misery, Shorten the Treatment Process, few intercurrent disease, improves Social benefit and economic benefit.
Claims (2)
1. treat a preparation method for the Chinese medicine composition oral liquid of pneumonia, it is characterized in that described oral liquid is prepared from by the raw material of following weight portion: Herba Hedyotidis Diffusae 20-30 part, Folium Isatidis 20-30 part, Fructus Arctii 12-18 part, Herba Taraxaci 12-18 part, Cortex Magnoliae Officinalis 12-18 part, Bulbus Fritillariae Thunbergii 6-10 part; Described preparation method comprises following processing step:
(1) get Herba Hedyotidis Diffusae, Folium Isatidis, Fructus Arctii, Herba Taraxaci, Cortex Magnoliae Officinalis and the Bulbus Fritillariae Thunbergii of recipe quantity, clean roguing, dry, pulverize;
(2) more above-mentioned graininess medical material is added to water and cover powder 2cm, soak 1-1.2h, pull medical material out and put multi-functional extraction and decoct with water secondary in filling with, add up for the first time the water that medical material 8-10 doubly measures, decoct 2h, get decocting liquid, filter, add up for the second time the water that medical material 6-8 doubly measures, decoct 1h, get twice decocting liquid and merge, filter the concentrated solution that while being concentrated into 90 ℃, relative density is 1.15;
(3) concentrated solution is set to 0 to-5 ℃ of deepfreeze 24h, cold preservation liquid is added to 0.3% filter aid kieselguhr, filter, filtrate reconcentration to every milliliter containing 2-3g crude drug amount, set to 0-5 ℃ of deepfreeze 24h, cold preservation liquid filtered, add or do not add correctives after pack and obtain oral liquid.
2. treat according to claim 1 the preparation method of the Chinese medicine composition oral liquid of pneumonia, it is characterized in that described oral liquid is prepared from by the raw material of following weight portion: 25 parts of Herba Hedyotidis Diffusaes, 25 parts of Folium Isatidiss, 15 parts of Fructus Arctiis, 15 parts of Herba Taraxacis, 15 parts of Cortex Magnoliae Officinalis, 8 parts of Bulbus Fritillariae Thunbergiis.
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| CN105521258A (en) * | 2016-03-09 | 2016-04-27 | 焦栋山 | Chinese herb composition of traditional Chinese internal medicine for pneumonia treatment |
| CN106038959A (en) * | 2016-06-01 | 2016-10-26 | 刘毅 | Traditional Chinese medicine composition for treating pneumonia and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816757A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating antiaditis and preparation method thereof |
| CN102512579A (en) * | 2011-12-27 | 2012-06-27 | 彭建 | Chinese medicine for adjuvant therapy of infant bronchitis or pneumonia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816757A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating antiaditis and preparation method thereof |
| CN102512579A (en) * | 2011-12-27 | 2012-06-27 | 彭建 | Chinese medicine for adjuvant therapy of infant bronchitis or pneumonia |
Non-Patent Citations (2)
| Title |
|---|
| 小儿肺炎中医药研究进展;赵霞等;《中医药研究》;20000831;第16卷(第4期);第57-59段 * |
| 赵霞等.小儿肺炎中医药研究进展.《中医药研究》.2000,第16卷(第4期),第57-59段. |
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