CN103040906B - Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof Download PDFInfo
- Publication number
- CN103040906B CN103040906B CN201310018999.8A CN201310018999A CN103040906B CN 103040906 B CN103040906 B CN 103040906B CN 201310018999 A CN201310018999 A CN 201310018999A CN 103040906 B CN103040906 B CN 103040906B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- spontaneous perspiration
- disease
- medicine composition
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to traditional Chinese medicine composition for treating spontaneous perspiration disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw traditional Chinese medicine in parts by weight: 20-80 parts of radix pseudostellariae and 20-80 parts of Wahlenbergia marginata. The invention further provides a preferable preparation method of the traditional Chinese medicine composition for treating the spontaneous perspiration disease. The traditional marketed medicine for treating the spontaneous perspiration disease is basically a medicine for treating a sweating disease and has defects that the curative effect is slow, the secretion of regular sweat glands is also sealed when the spontaneous perspiration disease is treated, the certain side effect exist; therefore, under the guidance of traditional Chinese medical theory, a medicine for treating the spontaneous perspiration disease with good effect, convenience in administration, good compliance and good safety is provided by utilizing reasonable compositions and combining with a modern preparation process; and the source of the raw materials is wide, the preparation process is simple, the cost is low and the preparation process is easy to be realized.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition being used for the treatment of disease of spontaneous perspiration, being specifically related to a kind of is Chinese medicine composition prepared by raw material with Chinese herbal medicine, the invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Common antiperspirant disease has hyperhidrosis, night sweat, spontaneous perspiration etc.Cause the main patient groups of antiperspirant disease to have: child, climacteric women, diabetics, tumor patient, tuberculosis patient and other also there will be many situations of perspiring as symptoms such as some rheumatic fever, hyperthyroidism, hypoglycemia.In general, antiperspirant disease is suffered from by current China, comprise sweating due to debility, night sweat, hyperhidrosis, spontaneous perspiration Crowds Distribute comparatively wide, about have 4,695 ten thousand patients, wherein child patient accounts for the ratio of 63%.Overall patient group using above-mentioned PATIENT POPULATION as an antiperspirant disease, the prevalence of China's antiperspirant disease is 3.6395%.In recent years, the Pharmaceutical retail market scale of China treatment sweating due to debility, night sweat and spontaneous perspiration is risen to about 1.75 hundred million yuan of 2002 by 1.2 hundred million yuan in 2000, annual rate of growth is between 14.19% ~ 18.54%.Although market scale is little, growth rate is very fast.2003, estimate that the retail market scale of this kind of medicine will reach to 2.56 hundred million yuan, by 2005 by breakthrough 400,000,000 yuan.
Spontaneous perspiration refers to that human body is because taking the factors such as sweating medicine or aggravating activities, heat, clothing be blocked up and natural sweater easily.Spontaneous perspiration, frequent sweating when waking up, activity more so, is more common in syndrome of deficiency of QI and syndrome of deficiency of blood.Because of yang-energy virtual loss, can not solid protection flesh table, Xuan Fu is not close, and body fluid leaks; Dynamic then consumption impairment of YANG gas, empty yang-energy consumes wound further, therefore movable after sweating more very.In addition, also can there is spontaneous perspiration in the deficiency of YIN, blood deficiency, disharmony of nutrient QI with defensive QI.Because deficiency of YIN-blood, YIN failing to keep YANG well, yang-energy applies outside Zhang Yu, and causing profound mansion can not be airtight, then from sweating.If disharmony of nutrient QI with defensive QI, battalion defends by force weak, folding mistake department, and Xuan Fu mistake is closed and from sweating.
At present, the primary treatment medicine as antiperspirant disease is fewer, China's medical market mainly contains the series of products such as XUHANTING and Yupingfeng, also has the medicine that ZHIBAI DIHUANG WAN, LIUWEI DIHUANG WAN etc. are relevant with treatment antiperspirant disease in addition.Not yet find that specialty is used for safety, the active drug of disease of spontaneous perspiration at present.
In recent years, the research finding effective disease of spontaneous perspiration medicine is comparatively active, and application number is a kind of decoction medicine and preparation method for the treatment of disease of spontaneous perspiration that to patent document discloses with Unguis Sus domestica, the Radix Astragali, Concha Ostreae, Fructus Tritici Levis, Radix Codonopsis, Fructus Schisandrae Chinensis, Radix Rehmanniae Preparata, Fructus Corni and Radix Glycyrrhizae Preparata be crude drug of 200610121198.4; Application number be 200810197291.2 patent document discloses a kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration made for crude drug with Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, the Radix Astragali, Radix Saposhnikoviae, Fructus Jujubae, Rhizoma Zingiberis Recens etc.; Application number be 201010224961.2 patent document discloses a kind of Chinese medicine preparation for the treatment of spontaneous perspiration, night sweat made for crude drug with the Radix Astragali, Fructus Tritici Levis, Fructus Jujubae, Radix Oryzae Glutinosae and Concha Ostreae (calcined); Application number be 201210136374.7 patent document discloses a kind of Chinese medicine constituent for the treatment of spontaneous perspiration made with 20 multi-flavor crude drug such as the Radix Astragali, Fructus Tritici Levis, Fructus Schisandrae Chinensis, Galla Chinensis, Semen Euryales, Halloysitum Rubrum, Limonitum, Fructus Rosae Laevigatae, Carapax Trionycis, Carapax et Plastrum Testudinis, Radix Trichosanthis.As everyone knows, Chinese medicine is the medical rarity of China, as long as confirm its effectiveness, has the advantage that chemical drugs is incomparable in safety.The Chinese medicine preparation of existing treatment disease of spontaneous perspiration or Chinese medicine composition are all follow drug matching principle by the Chinese herbal medicine more than 4 tastes to research and develop obtained, and part Chinese herbal medicine is expensive, and the Chinese medicine preparation obtained with this or Chinese medicine composition are difficult to obtain extensive popularization.
Therefore, in the face of vast disease of spontaneous perspiration patient, find a kind of effectively, safety and the spontaneous perspiration medicine of reasonable price, just seem extremely important.
Summary of the invention
The invention reside in and a kind of Chinese medicine composition for the treatment of spontaneous perspiration safely and effectively and preparation method thereof is provided.Substantially be antiperspirant disease medicine for the medicine for the treatment of spontaneous perspiration in the market, curative effect is slow, also encloses the secretion of normal sweat gland, have the defect of certain side effect while treatment spontaneous perspiration.The present invention is under the guidance of traditional Chinese medical science traditional theory, and reasonable formula, in conjunction with Modern preparations preparation technology, invents a kind of effective, taking convenience, compliance are good, safety is good treatment spontaneous perspiration medicine.Its raw material sources are extensive, preparation technology is simple, with low cost, be easy to realize.
The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, and described Chinese medicine composition is the medicament be made up of the raw material of Chinese medicine of following weight portion: Radix Pseudostellariae 20 ~ 80 parts, Radix Wahlenbergiae Marginatae 20 ~ 80 parts.
The weight portion preparing the preferred raw material of Chinese medicine of Chinese medicine composition of the present invention is: Radix Pseudostellariae 30 ~ 70 parts, Radix Wahlenbergiae Marginatae 35 ~ 65 parts.
Optimum weight part of Chinese medicine composition of the present invention is: Radix Pseudostellariae 40 parts, Radix Wahlenbergiae Marginatae 60 parts.
Radix Ophiopogonis, the Fructus Tritici Levis of suitable weight portion can also be added in described Chinese medicine composition.Described medicament is add the oral formulations that the acceptable adjuvant of pharmacy is prepared from.
Described oral formulations comprises decoct, tablet, capsule, granule, oral liquid, powder, powder.
Chinese medicine composition of the present invention can adopt the customary preparation methods of Chinese medicine to prepare, and above-mentioned each raw material of Chinese medicine is made the preferred production method of Chinese medicine composition of the present invention is:
(1) accurately take Radix Pseudostellariae and Radix Wahlenbergiae Marginatae, be crushed to 120 order fine powders respectively or separately;
(2) by certain solid-liquid ratio 1/1 ~ 1/8, add water, under room temperature, soak 0.5 ~ 2h;
(3) decoct 0.5 ~ 2h, filter, residue adds water by certain solid-liquid ratio 1/1 ~ 1/8 and again decocts, steaming and decocting 2 ~ 3 times, and merge decoction liquor, residue discards;
(4) the suitable method of decoction liquor concentrates, and adds the acceptable adjuvant granulation of appropriate pharmacy, drying, then is prepared into oral formulations as required.
On highly preferred, institute's step (2) and (3) middle solid-liquid ratio are 1/2.
Beneficial effect:
Radix Pseudostellariae is the dried root of Caryophyllaceae Pseudostellaria Pax plant Radix Ginseng, another name Radix Ginseng, Tong Can, two batches seven, and Radix Codonopsis Lanceolatae or rice ginseng are conventional Chinese medicine.All there is distribution all parts of the country, main product in Jiangsu, Anhui, Shandong, the province such as Fujian." Chinese Pharmacopoeia " records has QI invigorating spleen reinforcing, effect of promoting the production of body fluid for nourishing the lung, is clinically usually used in that insufficiency of the spleen body is tired, inappetence, children's are weak, the disease such as dyspepsia, after being ill weakness, deficiency of both vital energy and Yin, spontaneous perspiration are thirsty, dryness of the lung dry cough.
Radix Wahlenbergiae Marginatae, another name baby grass, Herba Euphorbiae Helioscopiae, bluet, cane ginseng, Isodon adenanthus (Diels) Kudo (Yunnan); Tank tank grass, Serpentis moss, Radix Adenophorae (Radix Glehniae) grass (Sichuan); Money hoist, cold grass (Fujian); Little green Herba Asari (Guizhou); Golden cudgel, hair drumsticks, Radix Adenophorae (Radix Glehniae), fine leaf adenophora (Hunan).Begin to be loaded in " the southern regions of the Yunnan Province book on Chinese herbal medicine ", record in the national standard such as Chinese Pharmacopoeia (version in 1977), " Yunnan Chinese crude drug standard ", " Fujian Province's Chinese crude drug standard " at present; On the south China the Changjiang river, all there is distribution each province to Southern Shaanxi, and its medicine resource is very abundant.Sweet in the mouth, micro-hardship, property is put down.Sweet flavour associating with spleen, Ku Renxin.Tonifying deficiency, only spontaneous perspiration, night sweat, except deficiency-heat.It is here raw that lid bothers then heart man deficiency-heat.With the sweet beneficial vigour of ginseng, and deficiency-heat is from removing also.Night is insomnia more, restless and sleepless, and painstaking effort are indefinite, mental derangement, and vim and vigour are not held back, therefore many spontaneous perspirations, night sweat.And all control it.
The present invention is under the guidance of traditional Chinese medical science traditional theory, in conjunction with the medicinal efficacy of Radix Pseudostellariae and Radix Wahlenbergiae Marginatae, by two taste Chinese herbal medicine organic assembling, dialectical compatibility and mutually assisting a ruler in governing a country, enhance effect of said composition YANG invigorating QI invigorating, strengthening superficial resistance to stop perspiration, provide a kind of Chinese medicine composition being specifically designed to treatment spontaneous perspiration, therapeutic effect is good, and side effect is low; And in conjunction with Modern preparations preparation technology, provide a method simple, cost-effective preparation method; Raw material sources of the present invention are extensive, are suitable for suitability for industrialized production, are beneficial to and apply.
detailed description of the invention:
Following Examples further illustrates the present invention, but should as restriction of the present invention.
Embodiment 1:
(1) accurately take Radix Pseudostellariae 40Kg and Radix Wahlenbergiae Marginatae 60Kg, be crushed to 120 order fine powders separately, merge;
(2) by certain solid-liquid ratio 1/4, add water, under room temperature, soak 0.5h;
(3) decoct 2h, filter, residue adds water by 1/2 solid-liquid ratio again, heated and boiled 1h, and filter, merge 2 filtrates, residue discards;
(4) decoction liquor is evaporated to concentration is 1.2 ~ 1.5g/mL, add the acceptable adjuvant of the pharmacy such as soluble starch, microcrystalline Cellulose to granulate, 60 DEG C of dryings, granulation intermediate every bag carries out subpackage according to Radix Pseudostellariae 10g, Radix Wahlenbergiae Marginatae 15g crude drug amount, obtains the granule that 4000 bags of confessions are oral.
Embodiment 2:
(1) accurately take Radix Pseudostellariae 2Kg and Radix Wahlenbergiae Marginatae 4Kg, be crushed to 120 order fine powders respectively;
(2) respectively add water by 1/4 solid-liquid ratio, under room temperature, soak 0.5h;
(3) decoct 2h, filter, residue adds water by 1/2 solid-liquid ratio again, heated and boiled 1h, and filter, merge 2 filtrates, residue discards;
(4) decoction liquor is evaporated to concentration is 1.2 ~ 1.5g/mL, add the acceptable adjuvant of the pharmacy such as soluble starch, microcrystalline Cellulose to granulate, 60 DEG C of dryings, merge Radix Pseudostellariae, Radix Wahlenbergiae Marginatae granulation intermediate, mixing, the purified water adding Sq is dissolved, and according to every bottle containing Radix Pseudostellariae 10g, Radix Wahlenbergiae Marginatae 20g crude drug amount dosage subpackage, obtains 200 bottles of oral liquid formulations that can for orally use.
Embodiment 3:
Connect certain, man, 30 years old, married, professional cadre, medical readme sweating while acting, examine that body of the tongue is light red, white and thin fur, thready pulse, belong to pattern of Spleen Qi deficiency disease of spontaneous perspiration, prescription: blue Semen arachidis hypogaeae radix pseudostellariae particles, take 2 every day, each one bag, be equivalent to Radix Pseudostellariae 10g, Radix Wahlenbergiae Marginatae 15g crude drug amount, take 7 days continuously, pay a return visit result: perspire and obviously reduce, be almost recovered.
Embodiment 4:
Permitted certain, female, 48 years old, married, medical readme nephritis history, hyperhidrosis usually, dynamic then more so, the body of the tongue of examining is light red, white and thin fur, moderate pulse, spontaneous sweating due to deficiency of QI, the blue Semen arachidis hypogaeae Taizi ginsen oral liquid of prescription, takes 2 every day, each one bottle, be equivalent to Radix Pseudostellariae 10g, Radix Wahlenbergiae Marginatae 15g crude drug amount, take 7 days continuously, pay a return visit result: perspire and obviously reduce, quality of life significantly improves.
Embodiment 5:
Composite preparation treatment general medicine deficient disease of spontaneous perspiration 35 example prepared by the present invention: collection study subject is old, weak and long-term chronic is sick, as the person that occurs spontaneous perspiration when primary symptom is treated stable at present such as atrophic gastritis (gastric abscess), slow kidney (lumbago), heart disease (cardiopalmus etc.), asthma, medication is all at one week, obvious improver 14 example of disease feelings, manifest symptom is improved, and spontaneous perspiration phenomenon disappears; Take a turn for the better 18 examples, and disease feelings were improved more in the past; Invalid 3 examples, still, effective percentage is 91% to disease feelings.
Claims (7)
1. treat a Chinese medicine composition for disease of spontaneous perspiration, it is characterized in that described Chinese medicine composition is the medicament be made up of the raw material of Chinese medicine of following weight portion: Radix Pseudostellariae 20 ~ 80 parts, Radix Wahlenbergiae Marginatae 20 ~ 80 parts.
2. the Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 1, wherein the weight portion of each raw material is: Radix Pseudostellariae 30 ~ 70 parts, Radix Wahlenbergiae Marginatae 35 ~ 65 parts.
3. the Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 1, wherein the weight portion of each raw material is: Radix Pseudostellariae 40 parts, Radix Wahlenbergiae Marginatae 60 parts.
4. the Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 3, is characterized in that described medicament is add the oral formulations that the acceptable adjuvant of pharmacy is prepared from.
5. the Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 4, is characterized in that described oral formulations comprises decoct, tablet, capsule, granule, oral liquid, powder, powder.
6., according to the preparation method of the Chinese medicine composition of the arbitrary described treatment disease of spontaneous perspiration of Claims 1 to 5, comprise the following steps:
(1) accurately take Radix Pseudostellariae and Radix Wahlenbergiae Marginatae, be crushed to 120 order fine powders respectively;
(2) by solid-liquid ratio 1/1 ~ 1/8, add water, under room temperature, soak 0.5 ~ 2h;
(3) decoct 0.5 ~ 2h, filter, residue adds water by solid-liquid ratio 1/1 ~ 1/8 and again decocts, and decocts 2 ~ 3 times, and merge decoction liquor, residue discards;
(4) the suitable method of decoction liquor concentrates, and adds the acceptable adjuvant granulation of appropriate pharmacy, drying, then is prepared into oral formulations as required.
7. the preparation method of the Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 6, is characterized in that in described step (2) and (3), solid-liquid ratio is 1/2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310018999.8A CN103040906B (en) | 2013-01-19 | 2013-01-19 | Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310018999.8A CN103040906B (en) | 2013-01-19 | 2013-01-19 | Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103040906A CN103040906A (en) | 2013-04-17 |
| CN103040906B true CN103040906B (en) | 2015-02-18 |
Family
ID=48053917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310018999.8A Active CN103040906B (en) | 2013-01-19 | 2013-01-19 | Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103040906B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716329A (en) * | 2012-06-23 | 2012-10-10 | 陈慧婷 | Tortoise shell TCM preparation for curing sweat syndromes and preparation method |
| CN102716363A (en) * | 2012-06-23 | 2012-10-10 | 陈慧婷 | Blighted wheat TCM preparation for curing sweat syndromes and preparation method |
-
2013
- 2013-01-19 CN CN201310018999.8A patent/CN103040906B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716329A (en) * | 2012-06-23 | 2012-10-10 | 陈慧婷 | Tortoise shell TCM preparation for curing sweat syndromes and preparation method |
| CN102716363A (en) * | 2012-06-23 | 2012-10-10 | 陈慧婷 | Blighted wheat TCM preparation for curing sweat syndromes and preparation method |
Non-Patent Citations (2)
| Title |
|---|
| 《兰花参止汗》;罗顺洪等;《云南中医杂志》;19811213(第05期);第25页 * |
| 《柘荣太子参的食用和药用价值》;张婕等;《海峡药学》;20111231;第23卷(第5期);第49页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103040906A (en) | 2013-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101549101B (en) | Traditional Chinese medicine for treating pneumoconiosis and drug-tolerant pulmonary tuberculosis and preparation method thereof | |
| CN103316249B (en) | Astragalus taxus chinensis capsule and preparing process thereof | |
| CN104306766B (en) | Prevent and treat Chinese medicinal formulae of patients with radioactive mucositis of oral cavity and preparation method thereof | |
| CN104435567A (en) | Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout | |
| CN103040906B (en) | Traditional Chinese medicine composition for treating spontaneous perspiration disease and preparation method thereof | |
| CN103768480B (en) | A kind of Chinese medicine for the treatment of facial spasm and preparation method thereof | |
| CN106177542A (en) | The Chinese prescription of a kind of summer heat clearing toxin resolving and goods thereof | |
| CN101020002B (en) | Compound Chinese medicine preparation for assisting tumor radiotherapy and its preparation method | |
| CN104800570A (en) | Chinese herbal preparation for treating pneumonia | |
| CN104367711A (en) | Pharmaceutical composition for treatment of mesenteric lymphadenitis in children | |
| CN104547369A (en) | Oral medicine for treating blepharospasm and preparation method thereof | |
| CN102406913A (en) | Chinese medicinal composition for treating melancholia | |
| CN103405723B (en) | Medicine composition for treating recurrent respiratory tract infection of children | |
| CN101843707B (en) | Chinese medicament for treating chronic hepatitis | |
| CN102266537B (en) | Chinese prepared medicine for treating chronic gastritis and gastroduodenal ulcer and preparation method thereof | |
| CN105727243A (en) | Chinese herbal composition for treating myocarditis and preparing method of Chinese herbal composition | |
| CN105169064A (en) | Medicinal preparation for whitening skin | |
| CN105360420A (en) | Dendrobium nobile Lindl grease-clearing tea | |
| CN104825735A (en) | Kidney-tonifying health wine | |
| CN103372121B (en) | Traditional Chinese medicine composition for treating tuberculosis and lung disease, and preparation method thereof | |
| CN105012391B (en) | Medicine for treating viral influenza and preparation method thereof | |
| CN104306457A (en) | Injection liquid for treating epidemic cerebrospinal meningitis and preparation method thereof | |
| CN104547103A (en) | Traditional Chinese medicinal composition for treating cardiac neurosis and preparation method of preparations thereof | |
| CN104127578A (en) | Traditional Chinese medicine composition for treating acute or chronic rhinitis and preparation method thereof | |
| CN101843678B (en) | Chinese medicament for treating climacteric syndromes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 355300 No.1 pharmaceutical industry road, Zherong County, Ningde City, Fujian Province Patentee after: Fujian Mindong lijiexin Pharmaceutical Co.,Ltd. Address before: 352000 Pharmaceutical Industrial Park, Tuorong County, Ningde City, Fujian Province Patentee before: Fujian Mindong Rejuvenation Pharmaceutical Co.,Ltd. |