CN103006705A - Haemorrhoids paste and preparation method thereof - Google Patents
Haemorrhoids paste and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of medicine, and in particular relates to a haemorrhoids paste and a preparation method thereof. The haemorrhoids paste can be used for shortening the cure course and comprises the following ingredients in parts by weight: 100-200 parts of badger fat, 1.5-4 parts of borneol, 1-3 parts of water, 0.1-0.4 parts of ammonium glycyrrhetate, 0.8-1.5 parts of vitamin B1, 0.8-1.5 parts of vitamin B2, 0.05-0.15 parts of vitamin B6 and 0.05-0.25 parts of anisodamine; the badger fat is molten within 40-60 DEG C; the molten badger fat is filtered; the borneol is added into the filtered badger fat so as to form a first mixture after the borneol is completely molten; ammonium glycyrrhetate, vitamin B1, vitamin B2, vitamin B6, and anisodamine are added into the 1-3 parts of water to be mixed and prepared into a first mixture solution; and the first mixture solution and the first mixture are mixed and uniformly stirred so as to form the haemorrhoids paste provided by the invention.
Description
Technical field
The present invention relates to field of medicaments, particularly ZHICHUANG GAO and preparation method.
Background technology
Hemorrhoid, it is a kind of common anal and intestinal disease, claim again hemorrhoid sick, under the human body rectum end mucosa and anal canal skin under venous plexus the formed soft vein of expansion and flexing group occurs, hemorrhoid comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, are a kind of chronic diseases of the vein group of the venous plexus generation varicose of anal orifice and rectal intestine bottom and anal mucosa and one or more softnesses of forming.
Usually the symptom of performance comprises: pruritus, have blood in stool pain.
The complication of hemorrhoid: 1. cause prolapsus, pause even necrosis, 2. having blood in stool for a long time easily causes anemia, 3. easily causes gynecological inflammation, 4. causes the long-term eczema of crissum.
The sick reason of sending out:
1. occupational relation: the people stands or sitting for a long time, and the long-term long journey of bearing a heavy burden affect venous return, makes in the pelvic cavity in the slow blood flow and abdomen internal organs congested, causes the haemorrhoidal vein over filling, and wall of vein tension force descends, and the easy blood stasis of blood vessel is expanded.Because of hypomotility, enterokinesia minimizing, the descending slow or habitual constipation of feces, can oppress and stimulate vein again, make contrafluxion and blood backflow obstacle, cause that the haemorrhoidal vein internal pressure raises, the wall of vein resistance reduces.
2. local excitation and eating and drinking without temperance: podex is caught a cold, is heated, constipation diarrhoea, excessive consumption of alcohol and eat maror more, all can stimulate anus and rectum, makes hemorrhoidal plexus congested, affect venous backflow, so that the decline of wall of vein resistance.
3. anal veins increased pressure: hard because of liver, become hepatohemia and cardiac function incompensation etc., all can make anal veins congested, increased pressure affects the hemorrhoidal veins blood backflow.
4. intraabdominal pressure increases: cross because of tumor, uterus tumor, ovarian tumor, prostate hyperplasia, the satiety of pregnant diet or Asiatic water closet pan in the abdomen and wait so long.All can make intra-abdominal pressure increase the blood backflow that hinders vein.
5. podex infects: hemorrhoidal plexus is first because of acute and chronic infection, and inflammation wall of vein Elastic tissue is fibrosis and dying down gradually, and resistance is not enough, and causes the expansion varicose, adds that other reason adds gradually varicosis and re-generates the hemorrhoid piece.The hemorrhoid piece mainly is made of matter between expansion of veins, spongy tissue and connective tissue.Venectasia is crooked, its wall attenuation, and adventitia and middle level atrophy, the elastic fibers tissue becomes vein that fibrous tissue also has without change in the wall.Intravenous can have thrombosis, and vein has clot outward.Active chronic inflammation is often arranged, as seen because of cellular infiltration, sometimes form microabscess.Spongy tissue is the rectum spongy body, is comprised of a lot of glomeruluses, and small artery short and small and that energy is crooked is arranged in the ball.Arteriovenous fistula is arranged sometimes, in the hemorrhoid piece, can touch arteriopalmus.The internal hemorrhoid surface is columnar epithelium, and the external hemorrhoid surface is squamous epithelial cancer.
Now common treatment for hemorrhoid mainly comprises: operation and external application.Because its pathological characteristic, caused it repeatedly to show effect, treat very complicatedly, by operation, relatively be not difficult to healing.
The problem that exists is, the operation instant effect, but cost is higher.The ointment of the external application of using now has multiple, is mainly used in timely alleviating pain, but whole curative effect is slow, and the healing cycle is long, and general healing time is between 20 days-30 days.
Summary of the invention
ZHICHUANG GAO provided by the invention and preparation method can shorten the healing cycle.
Technical scheme of the present invention is achieved in that ZHICHUANG GAO, and meter comprises: Adeps melis 100-200 part, Borneolum Syntheticum 1.5-4 part, water 1-3 part, ammonium glycyrrhizinate 0.1-0.4 part, vitamin B by weight
10.8-1.5 part, vitamin B
20.8-1.5 part, vitamin B
60.05-0.15 part and Anisodamine 0.05-0.25 part.
The preparation method of above-mentioned ZHICHUANG GAO comprises:
100-200 part Adeps melis is melted between the 40-60 degree celsius temperature;
Described Adeps melis after the fusing is filtered;
Add 1.5-4 part Borneolum Syntheticum in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
In 1-3 part water, add 0.1-0.4 part ammonium glycyrrhizinate, 0.8-1.5 part vitamin B
1, 0.8-1.5 part vitamin B
2, 0.05-0.15 part vitamin B
6, 0.05-0.25 part Anisodamine, fully stir, mix homogeneously forms the first mixed solution;
Described the first mixture and described the second mixed solution mixed and stir to obtain ZHICHUANG GAO provided by the present invention.
Compared with prior art, in the ZHICHUANG GAO provided by the present invention, mainly be the ointment of making take Adeps melis as guiding drug, writing Adeps melis according to Li Shizhen (1518-1593 A.D.) in Compendium of Material Medica " has the effect of coming back to life ".From observing clinically, Adeps melis has good sterilization, sterilizing function can promote cell regeneration simultaneously.So the present invention uses in ZHICHUANG GAO Adeps melis as main curative effect composition.
Simultaneously, added therein Borneolum Syntheticum, the pharmacology of Borneolum Syntheticum is: have the effect that the pain relieving removing heat from blood reduces cicatrix;
And with 0.1-0.4 part ammonium glycyrrhizinate, 0.8-1.5 part vitamin B
1, 0.8-1.5 part vitamin B
2, 0.05-0.15 part vitamin B
6, 0.05-0.25 part Anisodamine adds in 1-3 part water and makes the first mixed solution, and the first mixed solution and the first mixture of making is mixed together, and stirs, and makes ZHICHUANG GAO provided by the present invention.
Wherein, ammonium glycyrrhizinate has good antiallergic effect, can be used for simultaneously coordinating the actions of various ingredients in a prescription thing composition;
Vitamin B
1Can the nutrition crissum neural, promote the skin growth.
Vitamin B
2Can treat anal skin coarse, so that the new skin that bears is smooth.
Vitamin B
6Can prevent the enteral nutrition Deficiency of Intake, required nutrition when replenishing growth to intestinal;
Anisodamine can relaxing smooth muscle, removes the blood capillary spasm, has good analgesic activity, can accelerate the speed that medicine enters skin inside.
And, clinical trial certificate, the patient is using ZHICHUANG GAO of the present invention after one week, and 98% patient returns to one's perfect health, and without recurrence; The patient of 1%-2% has obvious curative effects.So ZHICHUANG GAO provided by the invention can shorten the healing cycle.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art, below will do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art, apparently, accompanying drawing in below describing only is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain according to these accompanying drawing illustrated embodiments other embodiment and accompanying drawing thereof.
Fig. 1 is the preparation method flow chart of the embodiment 1 of ZHICHUANG GAO provided by the invention;
Fig. 2 is the preparation method flow chart of the embodiment 2 of ZHICHUANG GAO provided by the invention;
Fig. 3 is the preparation method flow chart of the embodiment 3 of ZHICHUANG GAO provided by the invention;
Fig. 4 is the preparation method flow chart of the embodiment 4 of ZHICHUANG GAO provided by the invention;
Fig. 5 is the preparation method flow chart of the embodiment 5 of ZHICHUANG GAO provided by the invention;
Fig. 6 is the preparation method flow chart of the embodiment 6 of ZHICHUANG GAO provided by the invention;
Fig. 7 is the preparation method flow chart of the embodiment 7 of ZHICHUANG GAO provided by the invention;
Fig. 8 is the preparation method flow chart of the embodiment 8 of ZHICHUANG GAO provided by the invention.
The specific embodiment
Below with reference to accompanying drawing the technical scheme of various embodiments of the present invention is carried out clear, complete description, obviously, described embodiment only is a part of embodiment of the present invention, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills are resulting all other embodiment under the prerequisite of not making creative work, all belong to the scope that the present invention protects.
Embodiment 1:
ZHICHUANG GAO, meter comprises: 100 parts of Adeps meliss, 1.5 parts of Borneolum Syntheticums, 1 part in water, 0.1 part of ammonium glycyrrhizinate, vitamin B by weight
10.8 part, vitamin B
20.8 part, vitamin B
60.05 0.05 part of part and Anisodamine.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 1,
101. 100 parts of Adeps meliss are melted in 40 degree celsius temperature;
102. the described Adeps melis after will melting filters, and filters out impurity wherein;
103. add 1.5 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
104. in 1 part of water, add 0.1 part of ammonium glycyrrhizinate, 0.8 part of vitamin B
1, 0.8 part of vitamin B
2, 0.05 part of vitamin B
6, 0.05 part of Anisodamine, fully mix and form the first mixed solution.
105. described the first mixture and described the first mixed solution are mixed, and stirring to obtain the ZHICHUANG GAO that the present embodiment provides.
Compared with prior art, in the ZHICHUANG GAO that the present embodiment provides, mainly be the ointment of making take Adeps melis as guiding drug, writing Adeps melis according to Li Shizhen (1518-1593 A.D.) in Compendium of Material Medica " has the effect of coming back to life ".From observing clinically, Adeps melis has good sterilization, sterilizing function can promote cell regeneration simultaneously.So among the present invention Adeps melis is used in ZHICHUANG GAO as main curative effect composition.
Simultaneously, added therein Borneolum Syntheticum, ammonium glycyrrhizinate, vitamin B
1, vitamin B
2, vitamin B
6And Anisodamine.
The pharmacology of above various compositions is:
Borneolum Syntheticum has the effect that the pain relieving removing heat from blood reduces cicatrix;
Ammonium glycyrrhizinate has good antiallergic effect, can be used for simultaneously coordinating the actions of various ingredients in a prescription thing composition;
Vitamin B
1Can the nutrition crissum neural, promote the skin growth.
Vitamin B
2Can treat anal skin coarse, so that the new skin that grows is smooth.
Vitamin B
6Can prevent the enteral nutrition Deficiency of Intake, required nutrition when replenishing growth to intestinal;
Anisodamine can relaxing smooth muscle, removes the blood capillary spasm, has good analgesic activity, can accelerate the speed that medicine enters skin inside.
And, clinical trial certificate, the patient is using ZHICHUANG GAO of the present invention after one week, and the patient more than 90% returns to one's perfect health, without recurrence; 10% patient has obvious curative effects.So ZHICHUANG GAO provided by the invention can shorten the healing cycle, improve curative effect.
Embodiment 2: ZHICHUANG GAO comprises: count by weight, comprising: 120 parts of Adeps meliss, 2 parts of Borneolum Syntheticums, 1 part in water, 0.2 part of ammonium glycyrrhizinate, 0.1 part of adrenalin hydrochloride, vitamin B
11.0 part, vitamin B
21.0 part, vitamin B
60.08 0.1 part of part and Anisodamine.Above each composition medicament mixed is stirred evenly, can obtain the ZHICHUANG GAO that the present embodiment provides.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 2,
201. 120 parts of Adeps meliss are melted in 50 degree celsius temperature;
202. the described Adeps melis after will melting filters, and filters out impurity wherein;
203. add 2 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
204. in 1 part of water, add 0.2 part of ammonium glycyrrhizinate, 0.1 part of adrenalin hydrochloride, 1 part of vitamin B
11.0 part vitamin B
20.08 part vitamin B
60.1 part Anisodamine fully mixes and forms the second mixed solution;
205. described the first mixture and described the second mixed solution are mixed, stir, namely form ZHICHUANG GAO provided by the present invention.
The present embodiment is added into adrenalin hydrochloride in embodiment 1, when patient's patient part amount of bleeding is too much, in order to prevent that patient from suffering a shock because of severe loss of blood, can use this ointment, because adrenalin hydrochloride wherein is a kind of antishock vasoactive drug, be used for the rescue of sudden cardiac arrest and the rescue of anaphylactic shock.Pharmacology is: the beta receptor of exciting cardiac muscle, conducting system and sinuatrial node, and myocardial contraction is strengthened, cardiac output increases, and conduction is accelerated and increased heart rate.Activate mucocutaneous and beta 2 receptor visceral vessel, especially renal artery obviously shrinks, and skeletal muscle and coronary artery are then expanded.Exciting bronchus beta 2 receptor makes bronchiectasis.Act on liver and fatty beta 2 receptor, promote hepatic glycogen and steatolysis, rising blood glucose.
Embodiment 3: ZHICHUANG GAO, meter comprises: 200 parts of Adeps meliss, 4 parts of Borneolum Syntheticums, 3 parts in water, 0.4 part of ammonium glycyrrhizinate, 0.6 part of glycine, vitamin B by weight
11.5 part, vitamin B
21.5 part, vitamin B
60.15 0.25 part of part and Anisodamine.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 3,
301. 200 parts of Adeps meliss are melted in 60 degree celsius temperature;
302. the described Adeps melis after will melting filters, and filters out impurity wherein;
303. add 4 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
304. in 3 parts of water, add 0.4 part of ammonium glycyrrhizinate, 0.6 part of glycine, vitamin B
11.5 part, vitamin B
21.5 part, vitamin B
60.15 0.25 part of part and Anisodamine fully mix and form the 3rd mixed solution;
305. described the first mixture and described the 3rd mixed solution are mixed, stir, can obtain the ZHICHUANG GAO that the present embodiment provides.
Above each composition medicament mixed is stirred evenly, can obtain the ZHICHUANG GAO that the present embodiment provides.The present embodiment has increased the glycine composition compared to the composition among the embodiment 1, and glycine is generally infused as amino acid nutrient aspect medical, can have additional nutrients for patient's affected part, promotes the affected part rehabilitation.
Embodiment 4: ZHICHUANG GAO, meter comprises: 100 parts of Adeps meliss, 1.5 parts of Borneolum Syntheticums, 1 part in water, 0.1 part of ammonium glycyrrhizinate, 0.3 part of glycine, 0.3 part of cysteine hydrochloride, vitamin B by weight
10.8 part, vitamin B
20.8 part, vitamin B
60.05 0.05 part of part and Anisodamine.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 4,
401. 100 parts of Adeps meliss are melted in 40 degree celsius temperature;
402. the described Adeps melis after will melting filters, and filters out impurity wherein;
403. add 1.5 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
404. in 1 part of water, add 0.1 part of ammonium glycyrrhizinate, 0.3 part of glycine, 0.3 part of cysteine hydrochloride, vitamin B
10.8 part, vitamin B
20.8 part, vitamin B
60.05 0.05 part of part and Anisodamine fully mix and make the 3rd mixed solution;
405. described the first mixture and described the 3rd mixed solution are mixed, and stirring to obtain the ZHICHUANG GAO that the present embodiment provides.
Above each composition medicament mixed is stirred evenly, can obtain the ZHICHUANG GAO that the present embodiment provides.The present embodiment has increased the cysteine hydrochloride composition compared to the composition among the embodiment 3, cysteine hydrochloride is amino acid drug, can be used for treating urethral disease, usually also be intended for one of amino acid whose nutritional labeling, the growth desired nutritional can be provided for patient's affected part.
Embodiment 5: ZHICHUANG GAO comprises: count by weight, comprising: 180 parts of Adeps meliss, 3 parts of Borneolum Syntheticums, 2 parts in water, 0.3 part of ammonium glycyrrhizinate, 0.5 part of chlorphenamine maleate, vitamin B
11.2 part, vitamin B
21.2 part, vitamin B
60.12 0.2 part of part and Anisodamine.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 5,
501. 180 parts of Adeps meliss are melted in 50 degree celsius temperature;
502. the described Adeps melis after will melting filters, and filters out impurity wherein;
503. add 3 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
504. in 2 parts of water, add 0.3 part of ammonium glycyrrhizinate, 0.5 part of chlorphenamine maleate, vitamin B
11.2 part, vitamin B
21.2 part, vitamin B
60.12 part and 0.2 part of Anisodamine fully mix, make the 3rd mixed solution;
505. described the first mixture and described the 3rd mixed solution are mixed, can obtain the ZHICHUANG GAO that the present embodiment provides.
The present embodiment has increased chlorphenamine maleate compared to the composition among the embodiment 4, chlorphenamine maleate has the effect of histamine H1-receptor on the stronger competitiveness blocking-up allergy target cell, play outside the anti-allergic effects by the antagonism to the H1 receptor, also has the effect of anti-M cholinoceptor, therefore can occur the symptoms such as xerostomia, constipation, sputum retrogradation, nasal mucosa drying after taking medicine.This medicine also has the effect of certain inhibition maincenter in addition, the sleepy untoward reaction after therefore can occurring taking medicine.
Embodiment 6: comprising: count by weight, comprising: 120 parts of Adeps meliss, 2 parts of Borneolum Syntheticums, 1 part in water, 0.2 part of ammonium glycyrrhizinate, 0.1 part of chlorphenamine maleate, 0.2 part of riboflavin sodium phosphate, vitamin B
11.0 part, vitamin B
21.0 part, vitamin B
60.08 0.1 part of part and Anisodamine.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 6,
601. 120 parts of Adeps meliss are melted in 40 degree celsius temperature;
602. the described Adeps melis after will melting filters, and filters out impurity wherein;
603. add 2 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
604. in 1 part of water, add 0.2 part of ammonium glycyrrhizinate, 0.1 part of chlorphenamine maleate, 0.2 part of riboflavin sodium phosphate, vitamin B
11 part, vitamin B
21 part, vitamin B
60.08 0.1 part of part and Anisodamine fully stir, mix homogeneously is made the 4th mixed solution;
605. described the first mixture and described the 4th mixed solution are mixed, stir, can obtain the ZHICHUANG GAO that the present embodiment provides.
The present embodiment has increased the riboflavin sodium phosphate composition compared to the composition among the embodiment 5, and riboflavin sodium phosphate has preferably antiinflammation, so use in the affected part, can prevent that the patient affected part from producing inflammation.
Embodiment 7: ZHICHUANG GAO comprises: 150 parts of Adeps meliss, 2.5 parts of Borneolum Syntheticums, 2 parts in water, 0.25 part of ammonium glycyrrhizinate, 0.4 part of chlorphenamine maleate, 0.4 part of riboflavin sodium phosphate, vitamin B
11.1 part, vitamin B
21.1 part, vitamin B
60.1 part, 0.6 part of 0.15 part of Anisodamine and nicotiamide.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 7,
701. 150 parts of Adeps meliss are melted in 45 degree celsius temperature;
702. the described Adeps melis after will melting filters, and filters out impurity wherein;
703. add 2.5 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
704. in 2 parts of water, add 0.25 part of ammonium glycyrrhizinate, 0.4 part of chlorphenamine maleate, 0.4 part of riboflavin sodium phosphate, vitamin B
11.1 part, vitamin B
21.1 part, vitamin B
60.1 part, 0.6 part of 0.15 part of Anisodamine and nicotiamide, fully mix, make the 4th mixed solution;
705. described the first mixture and described the 4th mixed solution are mixed, can obtain the ZHICHUANG GAO that the present embodiment provides.
The present embodiment has increased the nicotiamide composition compared to the composition among the embodiment 6, and nicotiamide is the amide of nicotinic acid (vitamin B3).Be mainly used in preventing and treating pellagra, stomatitis, glossitis, sick sinus syndrome, the problems such as atrioventricular block.So added the smooth of new flesh that the nicotiamide composition can promote that the disease affected part grows in the present embodiment.
Embodiment 8: ZHICHUANG GAO comprises: 180 parts of Adeps meliss, 3 parts of Borneolum Syntheticums, 3 parts in water, 0.3 part of ammonium glycyrrhizinate, 0.5 part of chlorphenamine maleate, 0.6 part of riboflavin sodium phosphate, vitamin B
11.2 part, vitamin B
21.2 part, vitamin B
60.12 part, 0.2 part of Anisodamine, 0.9 part of nicotiamide, 0.5 part of dextro calcium pantothenate.
The preparation method of above-mentioned ZHICHUANG GAO comprises: as shown in Figure 8,
801. 180 parts of Adeps meliss are melted in 60 degree celsius temperature;
802. the described Adeps melis after will melting filters, and filters out impurity wherein;
803. add 3 parts of Borneolum Syntheticums in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
804. in 3 parts of water, add 0.3 part of ammonium glycyrrhizinate, 0.5 part of chlorphenamine maleate, 0.6 part of riboflavin sodium phosphate, vitamin B
11.2 part, vitamin B
21.2 part, vitamin B
60.12 part, 0.2 part of Anisodamine, 0.9 part of nicotiamide, 0.5 part of dextro calcium pantothenate fully mix, and make the 4th mixed solution;
805. described the first mixture and described the 4th mixed solution are mixed, and stirring to obtain the ZHICHUANG GAO that the present embodiment provides.
The present embodiment has increased the Acidum Pantothenicum calcium component compared to the composition among the embodiment 7.Dextro calcium pantothenate has another name called D-VB5 calcium, vitamin B5, is mainly used in all kinds of preparations such as tablet, capsule, oral liquid, electuary in the pharmaceuticals industry.After dextro calcium pantothenate enters animal or human's body, can participate in vivo the analytic metabolism function, participate in the synthetic of fatty acid, degrade and discharge large energy, promote those synthetic to the resistive antibody of pathogen, promote animal or human's body to absorption and the utilization of various nutrient substance.
The characteristic of the ZHICHUANG GAO of making according to above each embodiment: light yellow, the flavor raw meat has refrigerant sense.
Using method: external with front cleaning anus, is applied to the anus affected part, one day 1-2 time.
Prompting: ointment is applied to after the affected part, is seated at electric blanket or with available heat sources baking 20-40 minute, can helps the skin quickening to the absorption of medicine.Simultaneously, the patient should eat fruit more, drinks water more.
The Rehabilitation case:
Case 1. patients; Mrs Li, 26 years old now, married, gestation 4 months because of dyschizia, was had blood in stool, and in pudendum pendant one week of pain, per anum refers to inspection, and tentative diagnosis is external hemorrhoid, and visible anus has the aubergine tuberosity of 1cmX0.5cm size outward, and matter is hard, and the sense of tenderness is arranged.
The ZHICHUANG GAO that the use embodiment of the invention 1 provides is after one week, and tuberosity disappears, pain obviously disappears, and the anus colour of skin is normal.
Through patient's readme:
For the first time medication has refrigerant sense, pain relief.
For the second time medication, without any sensation, the stool depletion of blood.
For the third time medication, defecation is smooth and easy.The 4th medication, anus pendant pain disappears.
Case 2. patients; Mr. Ma, 40 years old now, Professional drivers, because proctalgia appears in sitting, pain increases the weight of during defecation, defecates hemorrhage.Can touch on inspection the soft tuberosity that the sense of touching a tender spot is arranged of matter of 1cm x0.5cm size, tentative diagnosis is the anus internal hemorrhoid.
The ZHICHUANG GAO that the use embodiment of the invention 3 provides is after one week, and proctalgia disappears, and defecation is smooth and easy, after an action of the bowels without hemorrhage.
Patient's readme:
For the first time medication has refrigerant sense, pain relief.
For the second time medication, pain disappears.
For the third time medication is defecated smooth and easy.
Case 3. patients, Mr. Wang, 70 years old now, the businessman, because of overtired, crissum pain, just before hemorrhage 3 months after an action of the bowels, through the routine of having a blood test, digital rectal examination, tentative diagnosis is anemia, mixed hemorrhoid, hemorrhoid be take pectinate line as the boundary, aubergine, matter is soft, and tenderness is arranged.
The ZHICHUANG GAO that the use embodiment of the invention 2 provides is after one week, and above-mentioned symptom is obviously alleviated.
Patient's readme:
For the first time medication has refrigerant sense, and pain disappears, and especially just pain is obviously alleviated.
For the second time medication, anemia is improved, crissum colour of skin light red, tuberosity disappears, without having blood in stool.
For the third time medication, defecation is smooth and easy, the stool depletion of blood.
Various embodiment provided by the invention can be as required in any way mutually combination, the technical scheme that obtains by this combination, also within the scope of the invention.
Obviously, those skilled in the art can carry out various changes and modification to the present invention and not break away from the spirit and scope of the present invention.Like this, if of the present invention these are revised and modification belongs within the scope of claim of the present invention and equivalent technologies thereof, then the present invention also comprises these changes and modification interior.
Claims (10)
1. ZHICHUANG GAO is characterized in that, meter comprises: Adeps melis 100-200 part, Borneolum Syntheticum 1.5-4 part, water 1-3 part, ammonium glycyrrhizinate 0.1-0.4 part, vitamin B by weight
10.8-1.5 part, vitamin B
20.8-1.5 part, vitamin B
60.05-0.15 part and Anisodamine 0.05-0.25 part.
2. ZHICHUANG GAO according to claim 1 is characterized in that, meter comprises: Adeps melis 120-180 part, Borneolum Syntheticum 2-3 part, water 1.5-2.5 part, ammonium glycyrrhizinate 0.2-0.3 part, vitamin B by weight
11.0-1.2 part, vitamin B
21.0-1.2 part, vitamin B
60.08-0.12 part and Anisodamine 0.1-0.2 part.
3. ZHICHUANG GAO according to claim 1 is characterized in that, meter comprises: 150 parts of Adeps meliss, 2 parts of Borneolum Syntheticums, 2 parts in water, 0.2 part of ammonium glycyrrhizinate, vitamin B by weight
11.0 part, vitamin B
21.0 part, vitamin B
60.1 0.1 part of part and Anisodamine.
4. according to claim 1, the ZHICHUANG GAO described in 2 or 3, it is characterized in that meter by weight also comprises following one or more composition:
Glycine 0.3-0.6 part;
Cysteine hydrochloride 0.3-0.6 part;
Chlorphenamine maleate 0.1-0.5 part.
5. ZHICHUANG GAO according to claim 4 is counted by weight, it is characterized in that, also comprises adrenalin hydrochloride 0.1-0.5 part.
6. ZHICHUANG GAO according to claim 4, meter is characterized in that by weight, also comprises following one or more composition:
Riboflavin sodium phosphate 0.2-0.6 part;
Nicotiamide 0.3-0.9 part;
Dextro calcium pantothenate 0.1-0.5.
7. a preparation method for preparing ZHICHUANG GAO as claimed in claim 1 is characterized in that, concrete steps comprise:
100-200 part Adeps melis is melted between the 40-60 degree celsius temperature;
Described Adeps melis after the fusing is filtered;
Add 1.5-4 part Borneolum Syntheticum in the described Adeps melis after filtration, treat that Borneolum Syntheticum melts formation the first mixture fully;
In 1-3 part water, add 0.1-0.4 part ammonium glycyrrhizinate, 0.8-1.5 part vitamin B
1, 0.8-1.5 part vitamin B
2, 0.05-0.15 part vitamin B
6, 0.05-0.25 part Anisodamine, fully stir, mix homogeneously is made the first mixed solution;
Described the first mixture and described the first mixed solution are mixed and stir.
8. the preparation method of ZHICHUANG GAO according to claim 7 is characterized in that, adds in described the first mixed solution that 0.1-0.5 part adrenalin hydrochloride fully stirs and mix homogeneously is made the second mixed solution again;
Described the first mixture and described the second mixed solution are mixed, and stir.
9. the preparation method of ZHICHUANG GAO according to claim 7, it is characterized in that, in described the first mixed solution, add again, 0.3-0.6 one or more in part glycine, 0.3-0.6 part cysteine hydrochloride, the 0.1-0.5 part chlorphenamine maleate fully mix and make the 3rd mixed solution;
Described the first mixture and described the 3rd mixed solution are mixed, and stir.
10. the preparation method of ZHICHUANG GAO according to claim 9, it is characterized in that, in described the 3rd mixed solution, add again in 0.2-0.6 part riboflavin sodium phosphate, 0.3-0.9 part nicotiamide, the 0.1-0.5 dextro calcium pantothenate one or more, mix and stir and make the 4th mixed solution;
Described the first mixture and described the 4th mixed solution are mixed, and stir.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726808A (en) * | 2016-03-25 | 2016-07-06 | 广西大学 | Preparation method of plaster used for treating haemorrhoids |
| CN110215453A (en) * | 2019-03-26 | 2019-09-10 | 山东省药学科学院 | It is a kind of for promoting the pharmaceutical formulation of skin wound healing |
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| CN1443558A (en) * | 2003-03-07 | 2003-09-24 | 范宝增 | Preparation method of Bingling ointment for curing burn and scald |
| CN1569175A (en) * | 2004-05-13 | 2005-01-26 | 李果 | Chinese medicine for treating burn and frostbite |
| CN1621052A (en) * | 2003-11-29 | 2005-06-01 | 马成明 | Multifunctional ointment for treating trauma |
| CN101361776A (en) * | 2008-09-26 | 2009-02-11 | 王云燕 | Scald ointment |
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2013
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1443558A (en) * | 2003-03-07 | 2003-09-24 | 范宝增 | Preparation method of Bingling ointment for curing burn and scald |
| CN1621052A (en) * | 2003-11-29 | 2005-06-01 | 马成明 | Multifunctional ointment for treating trauma |
| CN1569175A (en) * | 2004-05-13 | 2005-01-26 | 李果 | Chinese medicine for treating burn and frostbite |
| CN101361776A (en) * | 2008-09-26 | 2009-02-11 | 王云燕 | Scald ointment |
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| 史书达: "《消化系统疾病防治奇效方》", 31 December 2010 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726808A (en) * | 2016-03-25 | 2016-07-06 | 广西大学 | Preparation method of plaster used for treating haemorrhoids |
| CN110215453A (en) * | 2019-03-26 | 2019-09-10 | 山东省药学科学院 | It is a kind of for promoting the pharmaceutical formulation of skin wound healing |
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| CN103006705B (en) | 2015-03-18 |
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