CN103006628A - Application of formaldehyde in preparation of injection for treating animal and human infectious disease - Google Patents
Application of formaldehyde in preparation of injection for treating animal and human infectious disease Download PDFInfo
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- CN103006628A CN103006628A CN2012105871033A CN201210587103A CN103006628A CN 103006628 A CN103006628 A CN 103006628A CN 2012105871033 A CN2012105871033 A CN 2012105871033A CN 201210587103 A CN201210587103 A CN 201210587103A CN 103006628 A CN103006628 A CN 103006628A
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- injection
- formaldehyde
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- sodium bicarbonate
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Abstract
The invention discloses a new application of formaldehyde in preparation of an injection for treating animal and human infectious diseases. The content of formaldehyde in the injection for treating different animals and human beings and the medication doses are determined. In Tens of thousands of cases of clinical practice, for the animal infectious diseases including swine fever disease, fowl plague disease, tetanus disease, foot and mouth disease, rabies, swine plague, flu, trypanosomosis, brucellosis, viral enteritis and the like, for the acute diseases, in which body temperature cannot drop naturally, and for the chronic diseases, in which a patient is extremely thin and has no denaturation in a certain organ, the diseases can be recovered by the treatment with the injections once, and the curative effect is definite; and the human infectious diseases, including hepatitis B, hepatitis C, chronic phthisis, acquired immunodeficiency syndrome and the like, can be recovered in 2-3 days.
Description
Technical field
The present invention relates to the new purposes of formaldehyde, especially the application in the injection of preparation treatment animal and human class infectious disease.
Background technology
Zoonosis such as hog cholera are acute, pernicious, destructive infectious disease, can't treat.Other zoonosis such as fowl plague disease, Tetanus, influenza, foot and mouth disease, rabies etc. all are infectious disease that infectiousness is strong, harm is large, generally prevent by vaccinate, some medicine that is used for the treatment of is only effective at the animal their early stage, and make loaded down with trivial details, cost is high, lacks determined curative effect, medicine that toxic and side effects is little.Formalin is used in the zoonotic injection of preparation treatment at present, gavages sodium bicarbonate in the time of injection of formaldehyde solution.Once can bring down a fever for swine fever injection, but recurrence is arranged, behind biphasic injection, could fully recover, unlikely repeated infection.
Hepatitis B, hepatitis C, chronic pulmonary tuberculosis, acquired immune deficiency syndrome (AIDS) etc. are that human common transmittable is sick, and it is propagated extensively, harm is large, lack at present the medicine of easy and determined curative effect.
Formaldehyde can be combined with the amino of protein, makes protein coagulating, pharmaceutically can be as antiseptic etc.When concentration and dosage were enough, this characteristic was all had a damage capability to most of microorganism, so also often as a kind of disinfectant.Formaldehyde had not been seen the report for human infectious disease's medicine for treatment so far as the anticorrosion medicine for external use of a kind of sterilization commonly used.
Summary of the invention
The object of the present invention is to provide the new application of formaldehyde in the injection of preparation treatment animal and human class infectious disease.
The present invention relates to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, contain formaldehyde and water for injection in the injection.
The present invention be more particularly directed to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, the weight percentage of formaldehyde is 0.06-0.08% in the injection, is used for intramuscular injection for treating birds infectious disease, is used simultaneously sodium bicarbonate.
The present invention be more particularly directed to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.08-0.2% in the injection, for pig the suffer from infectious disease of intramuscular injection for treating body weight less than 100 kilograms, be used sodium bicarbonate when because of excretory function obstacle being arranged.
The present invention be more particularly directed to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.2-2% in the injection, for pig the suffer from infectious disease of intramuscular injection for treating body weight greater than 100 kilograms, be used sodium bicarbonate when because of excretory function obstacle being arranged.
The present invention be more particularly directed to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 2-4.5% in the injection, be used for intramuscular injection for treating bovine infectious disease, be used sodium bicarbonate when because of excretory function obstacle being arranged.
The present invention be more particularly directed to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.006-0.008% in the injection, is used for intravenous injection treatment infectious disease that the adult suffers from.
The present invention also is particularly related to the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, and it is characterized in that: the weight percentage of formaldehyde is 0.07-0.08% in the injection, is used for intramuscular injection for treating infectious disease that the adult suffers from.
Formaldehyde is simple to operation with intramuscular injection to be the technical scheme of veterinary's attribute.During injection, produce local myalgia for preventing alone formaldehyde, need allocate 0.1～2% alcohol into, such as glycerol, ethanol, benzyl alcohol, methanol etc. as analgesics.
Some is sick plants sick body and must be used simultaneously sodium bicarbonate because of what excretory function had an obstacle, enter and produce formic acid in the body and savings causes toxic and side effects to eliminate formaldehyde, sodium bicarbonate can in and formaldehyde oxygen with body in be combined the formic acid of generation, so can not produce toxic and side effects.Its chemical equation is as follows: HCOH+O
2→ HCOOH, HCOOH+NaHCO
3→ HCOONa+H
2O+CO
2
The formaldehyde injection must be used simultaneously swine Fever Vaccine and prevent its repeated infection during the treatment swine fever.Using in the time of formaldehyde and swine Fever Vaccine is that a kind for the treatment of means is again a kind of antagonism process, keep the balance of the two to carry out.
The invention provides the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease, determined formaldehyde in treatment different animals and the human injection content and dosage.In tens thousand of routine clinical practices, to comprising the zoonosis of hog cholera, fowl plague disease, Tetanus, foot and mouth disease, rabies, pig lung plague, influenza, trypanosoma guyanense disease, brucellosis and viral enteritis etc., treatment do not have degeneration for sick body temperature certain internal organs naturally that descend, the prolonged illness skeletonize of planting of acute, as long as once can be fully recovered and determined curative effect.To comprising the human infectious disease of hepatitis B, hepatitis C, chronic pulmonary tuberculosis, acquired immune deficiency syndrome (AIDS) etc., all can in 2-3 days, fully recover.
The specific embodiment
Among the present invention the formaldehyde injection for the treatment of animal and human class infectious disease raw materials used be 35%～40% formalin and analytically pure glycerol, ethanol, benzyl alcohol or methanol, all to select to produce in the recent period, formaldehyde with the naked eye visual clarity is qualified, if polymerization can not be made used for intravenous injection.The filter of used for intravenous injection is strict.The injection solvent for use is water for injection.
The formaldehyde injection for the treatment of animal and human class infectious disease is in the application of clinical practice among the present invention, and birds does the chest muscle injection; Pig does the injection of cervical muscle deep; Cattle does the intramuscular injection of any part; The people makes intravenous injection or intragluteal injection.
The formaldehyde injection of the infectious disease such as treatment swine fever, rabies, Tetanus, viral enteritis, influenza, fowl plague disease must be used sodium bicarbonate simultaneously.Brucellosis class infectious disease can exempt to use sodium bicarbonate, so that formaldehyde is kept the time of valid density in blood longer.Animal is gavaged tablet or the powder of sodium bicarbonate, and perhaps the intravenous injection sodium bicarbonate injection also can be penetrated sodium bicarbonate injection in the animal back intramuscular injection.
Treatment during swine fever and the swine Fever Vaccine that is used simultaneously of formaldehyde injection make intragluteal injection.
In order further to understand the present invention, below be explained with embodiment.Need to prove that following examples only as enumerating, should not be considered as the restriction to scope of the present invention.
The application of embodiment 1 formaldehyde injection in the hog cholera pig of the intensive cultivation for the treatment of
The consumption of content, dosage and the sodium bicarbonate solution of formaldehyde or sodium bicarbonate sheet, swine Fever Vaccine is as shown in table 1 below in its formaldehyde injection.Wherein the piglets body weight is 15～20 kilograms; 18～35 kilograms of little feeder pig body weight; 40～60 kilograms of big rack pig body weight; 260～330 kilograms of sow body weight.Wherein the formaldehyde injection is done the injection of cervical muscle deep, and sodium bicarbonate injection is done the dorsal muscles injection, and the sodium bicarbonate sheet gavages, and swine Fever Vaccine is made intragluteal injection; " healing " expression one-time treatment and determined curative effect.
Table 1
| Time | Type | Content of formaldehyde in the formaldehyde injection | Formaldehyde injection consumption (milliliter/head) | Sodium bicarbonate injection or sodium bicarbonate consumption/head | Swine Fever Vaccine (head part) | Cure a number |
| 2004.4.10 | Little feeder pig | 0.08% | 10~15 | 60 ~ 80 | 4~6 | 68 |
| 2011.12.14 | Little feeder pig | 0.08% | 8~12 | 40 ~ 60 milliliters | 5~6 | 48 |
| 2011.12.17 | Piglets | 0.08% | 3~6 | 15 ~ 20 milliliters | 4 | 6 |
| 2011.12.17 | The big rack pig | 0.08% | 10~15 | 60 ~ 80 milliliters | 6~8 | 81 |
| 2011.12.17 | Sow | 2% | 20 | 120 milliliters | 12 | 22 |
The application of embodiment 2 formaldehyde injections in treatment hoof-and-mouth disease pig
The consumption of content, dosage and the sodium bicarbonate solution of formaldehyde is as shown in table 2 below in its formaldehyde injection.Wherein the piglets body weight is 15～20 kilograms; 18～35 kilograms of little feeder pig body weight; 40～60 kilograms of big rack pig body weight; 120～200 kilograms of sow body weight.Wherein the formaldehyde injection is done the injection of cervical muscle deep, and sodium bicarbonate injection is done the dorsal muscles injection.
Table 2
| Type | Content of formaldehyde in the formaldehyde injection | Formaldehyde injection consumption (milliliter/head) | Sodium bicarbonate injection consumption/head | Cure a number |
| Little feeder pig | 0.08% | 8~12 | 40 ~ 60 milliliters | 35 |
| Piglets | 0.08% | 3~6 | 15 ~ 20 milliliters | 17 |
| The big rack pig | 0.2% | 5~10 | 60 ~ 80 milliliters | 52 |
| Sow | 0.2% | 15~20 | 100 ~ 120 milliliters | 30 |
The application of embodiment 3 formaldehyde injections in treatment draft cattle infectious disease
Content, dosage and the sodium bicarbonate solution of formaldehyde or sodium bicarbonate sheet consumption are as shown in table 3 below in its formaldehyde injection.Wherein cattle is with the formaldehyde injection of low consumption, and Babalus bubalis L. is with the formaldehyde injection of high consumption.The formaldehyde injection is done intramuscular injection, and sodium bicarbonate injection is done the muscle of back injection, and the sodium bicarbonate sheet gavages.
Table 3
| Case | Content of formaldehyde in the formaldehyde injection | Formaldehyde injection consumption (milliliter/head) | Sodium bicarbonate injection or sodium bicarbonate consumption/head | Cure a number |
| Tetanus | 4.5% | 15~20 | 200 ~ 250 milliliters | 5 |
| African trypanosomiasis | 2% | 18~20 | 200 ~ 250 | 31 |
| Brucellosis | 4% | 15~20 | 0 | 16 |
| The cattle hemorrhagic septicemia | 2% | 10~15 | 200 ~ 300 | 8 |
| Rabies | 2% | 16~20 | 150 ~ 200 milliliters | 2 |
The application of embodiment 4 formaldehyde injections in treatment chicken infectious disease
The content of formaldehyde, dosage and sodium bicarbonate sheet consumption are as shown in table 4 below in its formaldehyde injection.The formaldehyde injection is done the chest muscle injection, and the sodium bicarbonate sheet gavages.
Table 4
The application of embodiment 5 formaldehyde injections in the treatment human infectious disease
Its injection system and dosage are as shown in table 5 below.Wherein intravenous injection contains 0.008% formaldehyde, and solvent is water for injection; The intragluteal injection agent contains 0.08% formaldehyde, and solvent is water for injection, and intravenous filter is strict.Intravenous injection is technical solution unique during the human infectious disease treats, and intramuscular injection is temporary therapeutic scheme.
Table 5
| Sequence number | Case | Sex | Age | Injection system | The injection consumption | Therapeutic effect |
| 1 | Hepatitis C | The woman | 39 | Intravenous injection | 30ml, injection once | Recovery from illness in 2-3 days |
| 2 | Hepatitis B | The woman | 37 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 3 | Hepatitis B | The man | 39 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 4 | Chronic pulmonary tuberculosis | The woman | 61 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 5 | Acquired immune deficiency syndrome (AIDS) | The woman | 29 | Intravenous injection | 30ml, injection once | Recovery from illness in 2-3 days |
| 6 | Acquired immune deficiency syndrome (AIDS) | The woman | 41 | Intravenous injection | 30ml, injection once | Recovery from illness in 2-3 days |
| 7 | Acquired immune deficiency syndrome (AIDS) | The woman | 40 | Intravenous injection | 30ml, injection once | Recovery from illness in 2-3 days |
| 8 | Acquired immune deficiency syndrome (AIDS) | The woman | 31 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 9 | Acquired immune deficiency syndrome (AIDS) | The man | 38 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 10 | Acquired immune deficiency syndrome (AIDS) | The woman | 36 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
| 11 | Rabies (doing promptly prevention) | The woman | 42 | Buttock injections | , inject twice in one day 5 ml/ time | 2 years without any symptom |
| 12 | Uterus carcinoma | The woman | 42 | Intravenous injection | 30ml, injection once | Recovery from illness in 2-3 days |
| 13 | Osteocarcinoma | The woman | 67 | Buttock injections | 5ml/ time, inject twice in one day | Recovery from illness in 2-3 days |
Claims (7)
1. the application of formaldehyde in the injection of preparation treatment animal and human class infectious disease is characterized in that: contain formaldehyde and water for injection in the injection.
2. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.06-0.08% in the injection, be used for intramuscular injection for treating birds infectious disease, be used simultaneously sodium bicarbonate.
3. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.08-0.2% in the injection, for pig the suffer from infectious disease of intramuscular injection for treating body weight less than 100 kilograms, be used sodium bicarbonate when because of excretory function obstacle being arranged.
4. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.2-2% in the injection, for pig the suffer from infectious disease of intramuscular injection for treating body weight greater than 100 kilograms, be used sodium bicarbonate when because of excretory function obstacle being arranged.
5. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 2-4.5% in the injection, be used for intramuscular injection for treating bovine infectious disease, be used sodium bicarbonate when because of excretory function obstacle being arranged.
6. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.006-0.008% in the injection, is used for intravenous injection treatment infectious disease that the adult suffers from.
7. the application of formaldehyde according to claim 1 in the injection of preparation treatment animal and human class infectious disease, it is characterized in that: the weight percentage of formaldehyde is 0.07-0.08% in the injection, is used for intramuscular injection for treating infectious disease that the adult suffers from.
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| CN2012105871033A CN103006628A (en) | 2012-12-31 | 2012-12-31 | Application of formaldehyde in preparation of injection for treating animal and human infectious disease |
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| CN2012105871033A CN103006628A (en) | 2012-12-31 | 2012-12-31 | Application of formaldehyde in preparation of injection for treating animal and human infectious disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4074310A4 (en) * | 2020-03-26 | 2024-01-10 | Laskavyi Vladislav Nikolaevich | Drug for treating coronaviral and retroviral infections and hepatitis c |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1276208A (en) * | 2000-05-15 | 2000-12-13 | 刘宗山 | Formaldehyde injection for treating infective diseases of animal |
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- 2012-12-31 CN CN2012105871033A patent/CN103006628A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1276208A (en) * | 2000-05-15 | 2000-12-13 | 刘宗山 | Formaldehyde injection for treating infective diseases of animal |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4074310A4 (en) * | 2020-03-26 | 2024-01-10 | Laskavyi Vladislav Nikolaevich | Drug for treating coronaviral and retroviral infections and hepatitis c |
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Application publication date: 20130403 |