CN102989538B - The clamping device of micro-fluidic chip - Google Patents

The clamping device of micro-fluidic chip Download PDF

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Publication number
CN102989538B
CN102989538B CN201210548787.6A CN201210548787A CN102989538B CN 102989538 B CN102989538 B CN 102989538B CN 201210548787 A CN201210548787 A CN 201210548787A CN 102989538 B CN102989538 B CN 102989538B
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Prior art keywords
slide block
chip
connector
cradling piece
micro
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CN201210548787.6A
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CN102989538A (en
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徐云鹏
燕春晖
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Jiangxi Zhonglan Electronic Manufacturing Co ltd
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JIANGXI CRYSTAL BIOSENSOR TECHNOLOGY Co Ltd
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Abstract

The present invention relates to clamping device, particularly relate to the clamping device of a kind of micro-fluidic chip.The clamping device of a kind of micro-fluidic chip, on described device pedestal, four limits are provided with support guide, and support guide is mounted with stent holder, by stent holder, support guide are hinged with cradling piece;Cradling piece is provided with multiple universal slide block, is installed with pole in universal slide block, and pole one end is provided with bayonet socket, and cradling piece top is provided with spacing granule;Stent holder is provided with fixing bolt, and universal slide block is provided with slide block and fixes bolt;Chip guide rail is provided with a pair and pulls button;Liquid injection port in microfluidic control chip is provided with connector, and connector end is provided with double-deck sucker.The present invention uses the three-dimensional structure design to handing over, pull button pressurizing block to solve the adaptability problem of multiposition interface;The mode that have employed connector bilayer sucker solves sealing joint problem;Spring is used to pull buckle structure to ensure the adaptability to different-thickness chip.

Description

The clamping device of micro-fluidic chip
Technical field
The present invention relates to clamping device, particularly relate to the clamping device of a kind of micro-fluidic chip.
Background technology
Microfluidic chip technology (Microfluidics) is that biological, chemistry, the sample of medical analysis process are prepared, instead Answer, separate, the basic operation unit such as detection is integrated on the chip of one piece of micro-meter scale, is automatically performed analysis overall process.Due to It is in the great potential in the field such as biology, chemistry, medical science, have been developed as a biology, chemistry, medical science, fluid, electronics, The brand-new research field of the subject crossing such as material, machinery.The latest development of the micro fluidic chip technical field world is introduced in report, in conjunction with Reporter's micro-fluidic chip for many years research and development achievement, introduces the chip manufacturing process technology of complete set and uniqueness, and multiple not Microchip with application.
When using micro-fluidic chip to carry out the various operation such as biochemical analysis, detection, sample and reagent are from micro-fluidic chip phase The liquid injection port answered is injected in fluid channel, and while generation detection sample injects, operation produces waste liquid can going out from chip Liquid mouth is constantly got rid of.What clamping device played connects the macroscopic views such as the fluid channel within micro-fluidic chip and common syringe exactly The effect of device.Along with the development of the subject such as biological, chemical, to the functional diversities of micro-fluidic chip and wanting of structure assembly Ask and improve constantly.The complexity of the flow passage structure of micro-fluidic chip carries compared with traditional cross electrophoresis chip the most significantly at present High.Same micro-fluidic chip generally comprises multiple liquid injection port and liquid outlet, is distributed in the diverse location of chip, and mutually away from From closely.This just following to clamping device proposition requirement:
L () clamping device to have suitable motility, to adapt to liquid injection port, liquid outlet be in the micro-fluidic of diverse location Chip.
(2) micro-fluidic chip that the design of clamping device structure is small and exquisite, less to adapt to interface spacing.
(3) there is good sealing, in order to avoid reagent goes out leakage from interface.
Summary of the invention
In order to overcome the shortcoming and defect of existing micro-fluidic chip interface mode, it is an object of the invention to provide and be applicable to There is a kind of microflow control chip clamping device of multiple liquid injection port and liquid outlet.
The present invention solves its technical problem and the technical scheme is that the clamping device of a kind of micro-fluidic chip, its structure Specifically include that liquid injection port, microfluidic control chip, device pedestal, chip guide rail, stent holder, pull button, support guide, fixing Bolt, universal slide block, slide block fix blank pipe, cradling piece in bolt, pole, spacing granule, connector, double-deck sucker, connector,
On described device pedestal, four limits are provided with support guide, support guide is mounted with stent holder, passes through support Holder makes support guide be hinged with cradling piece;Cradling piece is provided with multiple universal slide block, is installed with pole in universal slide block, Pole one end is provided with bayonet socket, and cradling piece top is provided with spacing granule;Stent holder is provided with fixing bolt, universal slide block It is provided with slide block and fixes bolt;Chip guide rail is provided with a pair and pulls button;
Liquid injection port in microfluidic control chip is provided with connector, and connector end is provided with double-deck sucker.
Described device base bottom surface is transparent baffle.
Described button of pulling is pulled for spring and is buckled.
The invention have the advantages that: this device uses the three-dimensional structure design to handing over, pull button pressurizing block to solve The adaptability problem of multiposition interface;The mode that have employed connector bilayer sucker solves sealing joint problem;Use spring Formula pulls buckle structure to ensure the adaptability to different-thickness chip.
Accompanying drawing explanation
Fig. 1 is one of which micro-fluidic chip planar structure schematic diagram of the present invention.
Fig. 2 is that the clamping device of micro-fluidic chip of the present invention is monolithically fabricated schematic diagram.
Fig. 3 is the floor map under many connector states of gripping apparatus grips of micro-fluidic chip of the present invention.
Fig. 4 is the schematic diagram of the connector bilayer sucker of the clamping device of micro-fluidic chip of the present invention.
1-liquid injection port in figure, 2-microfluidic control chip, 3-device pedestal, 4-chip guide rail, 5-stent holder, 6-pulls Button, 7-support guide, 8-fixes bolt, the universal slide block of 9-, and 10-slide block fixes bolt, 11-pole, the spacing granule of 12-, and 13-joins Knot device, 14-bilayer sucker, blank pipe in 15-connector, 16-cradling piece.
Detailed description of the invention
The detailed description of the invention of the present invention is made a detailed explanation by 1-4 below in conjunction with the accompanying drawings.
Embodiment: the clamping device of a kind of micro-fluidic chip, its structure specifically include that liquid injection port 1, microfluidic control chip 2, Device pedestal 3, chip guide rail 4, stent holder 5, pull button 6, support guide 7, fixing bolt 8, universal slide block 9, slide block are fixed Blank pipe 15, cradling piece 16 in bolt 10, pole 11, spacing granule 12, connector 13, double-deck sucker 14, connector,
On described device pedestal 3, four limits are provided with support guide 7, support guide 7 is mounted with stent holder 5, passes through Stent holder 5 makes support guide 7 be hinged with cradling piece 16;Cradling piece 16 is provided with multiple universal slide block 9, universal slide block Being installed with pole 11 in 9, pole 11 1 end is provided with bayonet socket, and cradling piece 16 top is provided with spacing granule 12;On stent holder 5 Being provided with fixing bolt 8, universal slide block 9 is provided with slide block and fixes bolt 10;Chip guide rail 4 is provided with a pair pulls button 6;
Liquid injection port 1 in microfluidic control chip 2 is provided with connector 13, and connector 13 end is provided with double-deck sucker 14.
Described device pedestal 3 bottom surface is transparent baffle.
The described button 6 pulled is pulled for spring and is buckled.
Whole operating process is done the most detailed step below illustrate: because its liquid injection port 1 of microfluidic control chip 2 has Multiple, and every kind of different its aperture position of microfluidic control chip 2 is all uncertain, so its support should be the most Become, and its fixed coordinates can be arbitrary.
Clamping work starts: first takes one piece of microfluidic control chip 2, pulls open button 6, is placed in device pedestal 3, Then will pull button 6 and buckle fixing.It is actually needed according to microfluidic control chip 2 and assigns the quantity of connector 13 to carry out assigning complete, Take a ruler and measure coordinate points, the fixing bolt 8 on stent holder 5 is unscrewed so that corresponding two cradling pieces 16 are permissible Move on support guide 7 according to the coordinate points that ruler determines, can determine that the coordinate of horizontal plane after moving, now tighten and prop up Fixing bolt 8 on frame holder 5.
Then, unscrew the slide block on cradling piece 16 and fix bolt 10 so that can glide on cradling piece 16 to slide block 9 Dynamic, pole 11 can pull and push with all directions.Because possible connector 13 has multiple, therefore pole 11 can be there is at same horizontal plane During upper support, the situation that two bars intersections crash occurs, and slide block 9 can slide up and down and create the multilevel layout of clamping, real Show three-dimensional clamping;After level, vertical two direction Coordinates calibrations, tighten slide block and fix bolt 10, it is achieved clamping purpose.
The effect of chip guide rail 4 is the adaptability size adjusting and disposing microfluidic control chip 2, in order to obtain good fixing Effect;Pull button 6 to pull for spring and to buckle to adapt to the various various thickness of microfluidic control chip 2;The spacing granule 12 on cradling piece 16 top Effect is to prevent universal slide block 9 from skidding off cradling piece 16;Device pedestal 3 bottom surface is that transparent baffle its purpose is to facilitate liquid stream To observation.
Connector 13 end is provided with double-deck sucker 14 effect two: one: seals liquid injection port 1 and connects with connector 13; Its two: position fixation.Its structure is: double-deck sucker 14 has inside and outside two-layer, when double-deck sucker 14 works, inside and outside it in two-layer Between position be in hollow, it is achieved attracting purpose.

Claims (1)

1. a clamping device for micro-fluidic chip, its structure specifically includes that liquid injection port (1), microfluidic control chip (2), device Pedestal (3), chip guide rail (4), stent holder (5), pull button (6), support guide (7), fixing bolt (8), universal slide block (9), slide block is empty in fixing bolt (10), pole (11), spacing granule (12), connector (13), double-deck sucker (14), connector Pipe (15), cradling piece (16),
It is characterized in that: upper four limits of device pedestal (3) are provided with support guide (7), support guide is mounted with stent holder on (7) (5), by stent holder (5), support guide (7) is hinged with cradling piece (16);Cradling piece (16) is provided with multiple ten thousand Being installed with pole (11) in slide block (9), universal slide block (9), pole (11) end is provided with bayonet socket, and cradling piece (16) top is arranged Limited location granule (12);Stent holder (5) is provided with fixing bolt (8), and universal slide block (9) is provided with slide block and fixes bolt (10);Chip guide rail (4) is provided with a pair pulls button (6);
Liquid injection port (1) in microfluidic control chip (2) is provided with connector (13), and connector (13) end is provided with double-deck sucker (14);
Described device pedestal (3) bottom surface is transparent baffle;
Described button (6) of pulling is that spring is pulled and buckled.
CN201210548787.6A 2012-12-17 2012-12-17 The clamping device of micro-fluidic chip Active CN102989538B (en)

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Application Number Priority Date Filing Date Title
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CN102989538B true CN102989538B (en) 2016-08-10

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109991195A (en) * 2019-04-24 2019-07-09 浙江警察学院 A kind of SPR detector single channel micro-fluidic chip clamping system
CN113019490B (en) * 2021-03-05 2024-06-07 苏州工业职业技术学院 Micro-control flow chip fixing clamp capable of being adjusted in micro mode

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323393A (en) * 1998-10-14 2001-11-21 卡钳技术有限公司 Microfluidic controller and detector system with self-calibration
CN101272850A (en) * 2005-09-27 2008-09-24 西门子公司 Modular microfluidic system
CN101303327A (en) * 2008-06-20 2008-11-12 浙江大学 Microflow control chip clamping device
CN101437618A (en) * 2006-05-11 2009-05-20 康宁股份有限公司 Modular mounting and connection or interconnection system for microfluidic devices
CN202962493U (en) * 2012-12-17 2013-06-05 江西恒盛晶微技术有限公司 Clamping device for micro-fluidic chip

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323393A (en) * 1998-10-14 2001-11-21 卡钳技术有限公司 Microfluidic controller and detector system with self-calibration
CN101272850A (en) * 2005-09-27 2008-09-24 西门子公司 Modular microfluidic system
CN101437618A (en) * 2006-05-11 2009-05-20 康宁股份有限公司 Modular mounting and connection or interconnection system for microfluidic devices
CN101303327A (en) * 2008-06-20 2008-11-12 浙江大学 Microflow control chip clamping device
CN202962493U (en) * 2012-12-17 2013-06-05 江西恒盛晶微技术有限公司 Clamping device for micro-fluidic chip

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Effective date of registration: 20200109

Address after: 330000 Nanchang 1, unit 702, Jiangxin District, 24 Jin Ping Road, Xihu District, Nanchang, Jiangxi.

Patentee after: Xu Yunpeng

Address before: 330096 hi tech building, No. 18, two hi tech Road, Nanchang hi tech Zone, Jiangxi, 512

Patentee before: JIANGXI CRYSTAL BIOSENSOR TECHNOLOGY Co.,Ltd.

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Effective date of registration: 20201209

Address after: 330000 south of 5th floor, building 15, No. 346, xiaolanzhong Avenue, Xiaolan economic and Technological Development Zone, Nanchang County, Nanchang City, Jiangxi Province

Patentee after: Jiangxi Zhonglan Electronic Manufacturing Co.,Ltd.

Address before: 330000 Nanchang 1, unit 702, Jiangxin District, 24 Jin Ping Road, Xihu District, Nanchang, Jiangxi.

Patentee before: Xu Yunpeng

CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Xu Yunpeng

Inventor after: Yan Chunhui

Inventor after: Liu Wencao

Inventor after: Zhou Yuxing

Inventor before: Xu Yunpeng

Inventor before: Yan Chunhui